| review article | Q7318358 |
| scholarly article | Q13442814 |
| P5530 | Altmetric DOI | 10.1111/BPH.13978 |
| P6179 | Dimensions Publication ID | 1091163898 |
| P356 | DOI | 10.1111/BPH.13978 |
| P953 | full work available at URL | http://eprints.whiterose.ac.uk/120525/ |
| P932 | PMC publication ID | 5980636 |
| P698 | PubMed publication ID | 28800673 |
| P1154 | Scopus EID | 2-s2.0-85029504102 |
| P50 | author | Hailin Zhang | Q88757399 |
| Nikita Gamper | Q41275613 | ||
| P2093 | author name string | David Jaffe | |
| Haixia Gao | |||
| Xiaona Du | |||
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| KCNQ/M currents in sensory neurons: significance for pain therapy. | Q44540560 | ||
| KCNQ2 is a nodal K+ channel. | Q44755361 | ||
| (S)-N-[1-(4-cyclopropylmethyl-3,4-dihydro-2H-benzo[1,4]oxazin-6-yl)-ethyl]-3-(2-fluoro-phenyl)-acrylamide is a potent and efficacious KCNQ2 opener which inhibits induced hyperexcitability of rat hippocampal neurons | Q44819241 | ||
| Synthesis and structure-activity relationship of acrylamides as KCNQ2 potassium channel openers | Q44893627 | ||
| Suppression of KCNQ/M (Kv7) potassium channels in dorsal root ganglion neurons contributes to the development of bone cancer pain in a rat model | Q44974884 | ||
| Meclofenamic acid and diclofenac, novel templates of KCNQ2/Q3 potassium channel openers, depress cortical neuron activity and exhibit anticonvulsant properties | Q45187314 | ||
| The new anticonvulsant retigabine favors voltage-dependent opening of the Kv7.2 (KCNQ2) channel by binding to its activation gate | Q45232112 | ||
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| Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine. | Q46497180 | ||
| Retigabine, the specific KCNQ channel opener, blocks ectopic discharges in axotomized sensory fibres | Q46709221 | ||
| Regulation of Kv7 (KCNQ) K+ channel open probability by phosphatidylinositol 4,5-bisphosphate. | Q46776132 | ||
| The KCNQ/M-current modulates arterial baroreceptor function at the sensory terminal in rats | Q46874608 | ||
| Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes | Q46907217 | ||
| Inositol triphosphate-mediated Ca2+ signals direct purinergic P2Y receptor regulation of neuronal ion channels | Q47838293 | ||
| M-channels modulate network excitatory activity induced by 4-aminopyridine in immature rat substantia gelatinosa in vitro | Q48091732 | ||
| Characterization of a novel high-potency positive modulator of K(v)7 channels | Q48094129 | ||
| Intracellular zinc activates KCNQ channels by reducing their dependence on phosphatidylinositol 4,5-bisphosphate | Q48112896 | ||
| Sequence determinants of subtype-specific actions of KCNQ channel openers | Q48120496 | ||
| Flupirtine enhances the anti-hyperalgesic effects of morphine in a rat model of prostate bone metastasis | Q48122660 | ||
| Observations on the morphology of axons and somata of slowly conducting dorsal root ganglion cells in the cat. | Q48194528 | ||
| Action potential propagation through embryonic dorsal root ganglion cells in culture. I. Influence of the cell morphology on propagation properties | Q72865038 | ||
| Spike-evoked suppression and burst patterning in dorsal root ganglion neurons of the rat | Q73397068 | ||
| Tactile allodynia in the absence of C-fiber activation: altered firing properties of DRG neurons following spinal nerve injury | Q73713513 | ||
| P2Y receptor linked to phospholipase C: stimulation of neuro 2A cells by UTP and ATP and possible regulation by protein kinase C subtype epsilon | Q73774889 | ||
| Mechanisms of neuropathic pain | Q79173262 | ||
| Kv7.2-7.5 voltage-gated potassium channel (KCNQ2-5) opener, retigabine, reduces capsaicin-induced visceral pain in mice | Q79447473 | ||
| The therapeutic potential of neuronal K V 7 (KCNQ) channel modulators: an update | Q81077718 | ||
| Ezogabine (retigabine) | Q85016585 | ||
| Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain | Q86044957 | ||
| Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research | Q89351448 | ||
| Axonal bifurcation in the dorsal root ganglion of the cat: a light and electron microscopic study | Q93691248 | ||
| Transcriptional repression of the M channel subunit Kv7.2 in chronic nerve injury | Q42119342 | ||
| The chemistry of pain production | Q42155638 | ||
| Effects of cold temperatures on the excitability of rat trigeminal ganglion neurons that are not for cold sensing | Q42528819 | ||
| G proteins of the Gq family couple the H2 histamine receptor to phospholipase C. | Q42551889 | ||
| KCNQ2/3 openers show differential selectivity and site of action across multiple KCNQ channels | Q42731239 | ||
| AKAP79/150 signal complexes in G-protein modulation of neuronal ion channels | Q42756534 | ||
| Enhancing m currents: a way out for neuropathic pain? | Q43071251 | ||
| Epigenetic gene silencing underlies C-fiber dysfunctions in neuropathic pain. | Q43112962 | ||
| Spike propagation through the dorsal root ganglia in an unmyelinated sensory neuron: a modeling study | Q43121407 | ||
| Novel KCNQ2/Q3 agonists as potential therapeutics for epilepsy and neuropathic pain | Q43216058 | ||
| Retigabine reduces the excitability of unmyelinated peripheral human axons | Q43556539 | ||
| Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine. | Q43683699 | ||
| Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis | Q44092262 | ||
| PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents | Q44386912 | ||
| KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man. | Q50432426 | ||
| The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels. | Q50646082 | ||
| Selective activation of vascular Kv 7.4/Kv 7.5 K+ channels by fasudil contributes to its vasorelaxant effect. | Q51455230 | ||
| Tannic acid modulates excitability of sensory neurons and nociceptive behavior and the Ionic mechanism. | Q51616423 | ||
| Synthesis and Evaluation of Potent KCNQ2/3-Specific Channel Activators. | Q51738570 | ||
| Activation of KCNQ2/3 potassium channels by novel pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives. | Q51767898 | ||
| Design, synthesis and biological activity of pyrazolo[1,5-a]pyrimidin-7(4H)-ones as novel Kv7/KCNQ potassium channel activators. | Q51769725 | ||
| Inhibition of M current in sensory neurons by exogenous proteases: a signaling pathway mediating inflammatory nociception. | Q51785375 | ||
| Pre- and postsynaptic activation of M-channels by a novel opener dampens neuronal firing and transmitter release. | Q51802961 | ||
| Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels. | Q51806762 | ||
| Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats. | Q51850252 | ||
| Suppression of KCNQ/M (Kv7) potassium channels in the spinal cord contributes to the sensitization of dorsal horn WDR neurons and pain hypersensitivity in a rat model of bone cancer pain. | Q53643135 | ||
| Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone | Q59066538 | ||
| Spontaneous activity in C-fibres after partial damage to the saphenous nerve in mice: Effects of retigabine | Q59889567 | ||
| Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition | Q60678441 | ||
| Retigabine-induced population primary afferent hyperpolarisation in vitro | Q60713099 | ||
| Failure of action potential propagation in sensory neurons: mechanisms and loss of afferent filtering in C-type units after painful nerve injury | Q61894795 | ||
| Peripheral nerve regeneration | Q68504287 | ||
| Unequal branch point filtering action in different types of dorsal root ganglion neurons of frogs | Q69873724 | ||
| A study of axonal diameters and areas in lumbosacral roots and nerves in the rat | Q71276215 | ||
| Angiotensin II inhibits calcium and M current channels in rat sympathetic neurons via G proteins | Q71629123 | ||
| Resolution of inflammation: the beginning programs the end | Q29615695 | ||
| Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin | Q29616107 | ||
| KCNQ5 channels control resting properties and release probability of a synapse | Q30471821 | ||
| The Concise Guide to PHARMACOLOGY 2015/16: Ligand-gated ion channels. | Q30488643 | ||
| The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels. | Q30488645 | ||
| The acute nociceptive signals induced by bradykinin in rat sensory neurons are mediated by inhibition of M-type K+ channels and activation of Ca2+-activated Cl- channels | Q30493890 | ||
| Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons | Q30519202 | ||
| Unexplained peculiarities of the dorsal root ganglion | Q33735038 | ||
| Peripheral KV7 channels regulate visceral sensory function in mouse and human colon. | Q33757330 | ||
| Activation of the Cl- channel ANO1 by localized calcium signals in nociceptive sensory neurons requires coupling with the IP3 receptor | Q34055806 | ||
| Targeting the voltage sensor of Kv7.2 voltage-gated K+ channels with a new gating-modifier | Q34100500 | ||
| Kinin receptors in pain and inflammation | Q34100735 | ||
| Isoform-specific prolongation of Kv7 (KCNQ) potassium channel opening mediated by new molecular determinants for drug-channel interactions | Q34107486 | ||
| Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats | Q34114419 | ||
| Flupirtine in pain management: pharmacological properties and clinical use. | Q34137890 | ||
| Neuronal KCNQ potassium channels: physiology and role in disease. | Q34185467 | ||
| Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels | Q34317893 | ||
| Pathways modulating neural KCNQ/M (Kv7) potassium channels | Q34464180 | ||
| Control of somatic membrane potential in nociceptive neurons and its implications for peripheral nociceptive transmission. | Q34585723 | ||
| Treatment of neuropathic pain: an overview of recent guidelines | Q35006269 | ||
| Augmentation of M-type (KCNQ) potassium channels as a novel strategy to reduce stroke-induced brain injury | Q35044810 | ||
| A change in configuration of the calmodulin-KCNQ channel complex underlies Ca2+-dependent modulation of KCNQ channel activity | Q35070168 | ||
| The individual and societal burden of chronic pain in Europe: the case for strategic prioritisation and action to improve knowledge and availability of appropriate care | Q35074737 | ||
| Oxidative modification of M-type K(+) channels as a mechanism of cytoprotective neuronal silencing | Q35102221 | ||
| Phosphoinositides regulate ion channels. | Q35192402 | ||
| Kv7.2 regulates the function of peripheral sensory neurons | Q35597965 | ||
| Kv7.5 is the primary Kv7 subunit expressed in C-fibers | Q35629778 | ||
| Information processing in the axon | Q35701106 | ||
| KCNQ channels in nociceptive cold-sensing trigeminal ganglion neurons as therapeutic targets for treating orofacial cold hyperalgesia | Q35906226 | ||
| G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition. | Q36322506 | ||
| A New Regulatory Mechanism for Kv7.2 Protein During Neuropathy: Enhanced Transport from the Soma to Axonal Terminals of Injured Sensory Neurons | Q36339749 | ||
| Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels | Q36447189 | ||
| Bradykinin inhibits M current via phospholipase C and Ca2+ release from IP3-sensitive Ca2+ stores in rat sympathetic neurons | Q36513808 | ||
| Modulation of K(v)7 potassium channels by a novel opener pyrazolo[1,5-a]pyrimidin-7(4H)-one compound QO-58 | Q36781082 | ||
| Kv7 (KCNQ) channel modulators and neuropathic pain | Q36815886 | ||
| Inflammatory mediator bradykinin increases population of sensory neurons expressing functional T-type Ca(2+) channels | Q36823117 | ||
| Triple cysteine module within M-type K+ channels mediates reciprocal channel modulation by nitric oxide and reactive oxygen species | Q36876339 | ||
| Regulation of ion transport proteins by membrane phosphoinositides | Q36986504 | ||
| Molecular pharmacology and therapeutic potential of neuronal Kv7-modulating drugs | Q37025352 | ||
| Regulation of neural KCNQ channels: signalling pathways, structural motifs and functional implications | Q37073174 | ||
| Activation of neuronal Kv7/KCNQ/M-channels by the opener QO58-lysine and its anti-nociceptive effects on inflammatory pain in rodents | Q37151594 | ||
| Potassium channels in peripheral pain pathways: expression, function and therapeutic potential | Q37362041 | ||
| Differential effects of selective cyclooxygenase-2 inhibitors on vascular smooth muscle ion channels may account for differences in cardiovascular risk profiles. | Q37415814 | ||
| Kv7 channels as targets for the treatment of pain | Q37482024 | ||
| Understanding inflammatory pain: ion channels contributing to acute and chronic nociception | Q37693805 | ||
| Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors | Q38052823 | ||
| Neuromodulation of cancer pain. | Q38084541 | ||
| K(V)7 potassium channels: a new therapeutic target in smooth muscle disorders. | Q38170911 | ||
| Kv7 channels as targets for anti-epileptic and psychiatric drug-development | Q38181290 | ||
| Accumulation of Kv7.2 channels in putative ectopic transduction zones of mice nerve-end neuromas | Q38267815 | ||
| Transient receptor potential vanilloid type 1 antagonists: a patent review (2011 - 2014). | Q38349917 | ||
| Selective repression of gene expression in neuropathic pain by the neuron-restrictive silencing factor/repressor element-1 silencing transcription (NRSF/REST). | Q38672415 | ||
| Discovery of a novel Kv7 channel opener as a treatment for epilepsy. | Q38873331 | ||
| Survey of Physicians' Understanding of Specific Risks Associated with Retigabine | Q38891897 | ||
| KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors | Q38915867 | ||
| Modulation of Kv7 channels and excitability in the brain | Q38958968 | ||
| Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability | Q39647545 | ||
| N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): a novel, selective KCNQ2/Q3 potassium channel activator. | Q40033485 | ||
| MrgD activation inhibits KCNQ/M-currents and contributes to enhanced neuronal excitability. | Q40144001 | ||
| Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants | Q40145551 | ||
| Ongoing activity in severed nerves: source and variation with time | Q40196570 | ||
| (S,E)-N-[1-(3-heteroarylphenyl)ethyl]-3-(2-fluorophenyl)acrylamides: synthesis and KCNQ2 potassium channel opener activity. | Q40480051 | ||
| Bradykinin and inflammatory pain | Q40485688 | ||
| Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1H-indol-5-yl)-ethyl acrylamides | Q40517409 | ||
| Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. | Q40721410 | ||
| Functional and molecular aspects of renal prostaglandin receptors | Q41113120 | ||
| Activation of peripheral KCNQ channels attenuates inflammatory pain | Q41943120 | ||
| Activation of P2Y1 nucleotide receptors induces inhibition of the M-type K+ current in rat hippocampal pyramidal neurons | Q41961727 | ||
| Functional significance of M-type potassium channels in nociceptive cutaneous sensory endings | Q41983600 | ||
| The Role of Kv7/M Potassium Channels in Controlling Ectopic Firing in Nociceptors | Q42061272 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | membrane protein | Q423042 |
| transport protein | Q2111029 | ||
| P304 | page(s) | 2158-2172 | |
| P577 | publication date | 2017-09-17 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | M-type K+ channels in peripheral nociceptive pathways | |
| P478 | volume | 175 |
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