| Q33615730 | 100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future |
| Q50074758 | A Calmodulin C-Lobe Ca2+-Dependent Switch Governs Kv7 Channel Function |
| Q37151699 | A KCNQ channel opener for experimental neonatal seizures and status epilepticus |
| Q51738464 | A Kv7.2 mutation associated with early onset epileptic encephalopathy with suppression-burst enhances Kv7/M channel activity. |
| Q36339749 | A New Regulatory Mechanism for Kv7.2 Protein During Neuropathy: Enhanced Transport from the Soma to Axonal Terminals of Injured Sensory Neurons |
| Q50869237 | A Schizophrenia-Related Deletion Leads to KCNQ2-Dependent Abnormal Dopaminergic Modulation of Prefrontal Cortical Interneuron Activity. |
| Q41476818 | A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂. |
| Q24534565 | A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly |
| Q36843204 | A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels. |
| Q35070168 | A change in configuration of the calmodulin-KCNQ channel complex underlies Ca2+-dependent modulation of KCNQ channel activity |
| Q44831415 | A conserved threonine in the S1-S2 loop of KV7.2 and K V7.3 channels regulates voltage-dependent activation |
| Q30475696 | A corticotropin-releasing factor system expressed in the cochlea modulates hearing sensitivity and protects against noise-induced hearing loss |
| Q34139587 | A genetic approach to understanding auditory function |
| Q47315471 | A new method to characterize function of the Drosophila heart by means of optical flow. |
| Q33781672 | A novel KCNQ1 nonsense variant in the isoform-specific first exon causes both jervell and Lange-Nielsen syndrome 1 and long QT syndrome 1: a case report |
| Q42820343 | A novel KCNQ4 pore-region mutation (p.G296S) causes deafness by impairing cell-surface channel expression. |
| Q92803732 | A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy |
| Q28239316 | A novel splicing mutation in KCNQ2 in a multigenerational family with BFNC followed for 25 years |
| Q39683080 | A pore residue of the KCNQ3 potassium M-channel subunit controls surface expression |
| Q47606893 | A possible link between KCNQ2- and STXBP1-related encephalopathies: STXBP1 reduces the inhibitory impact of syntaxin-1A on M current. |
| Q33312365 | A tale of switched functions: from cyclooxygenase inhibition to M-channel modulation in new diphenylamine derivatives |
| Q28574598 | AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists |
| Q37160148 | Action potential initiation and propagation: upstream influences on neurotransmission |
| Q50959625 | Activation of KCNQ Channels Suppresses Spontaneous Activity in Dorsal Root Ganglion Neurons and Reduces Chronic Pain after Spinal Cord Injury. |
| Q40745093 | Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352. |
| Q79896585 | Activation of epidermal growth factor receptor inhibits KCNQ2/3 current through two distinct pathways: membrane PtdIns(4,5)P2 hydrolysis and channel phosphorylation |
| Q43683699 | Activation of expressed KCNQ potassium currents and native neuronal M-type potassium currents by the anti-convulsant drug retigabine. |
| Q30369892 | Activation of m1 muscarinic acetylcholine receptor induces surface transport of KCNQ channels through a CRMP-2-mediated pathway. |
| Q41943120 | Activation of peripheral KCNQ channels attenuates inflammatory pain |
| Q38065150 | Activity-dependent callosal axon projections in neonatal mouse cerebral cortex |
| Q30480012 | Advances in Auditory and Vestibular Medicine |
| Q37402286 | Affinity for phosphatidylinositol 4,5-bisphosphate determines muscarinic agonist sensitivity of Kv7 K+ channels |
| Q35056777 | Amazing chloride channels: an overview |
| Q46459127 | An M-like potassium current in the guinea pig cochlea. |
| Q36175957 | An inactivation gate in the selectivity filter of KCNQ1 potassium channels |
| Q42594497 | Ancillary subunits and stimulation frequency determine the potency of chromanol 293B block of the KCNQ1 potassium channel. |
| Q43263581 | Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K+ channels |
| Q53832064 | Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid. |
| Q37726585 | Axon initial segment dysfunction in epilepsy |
| Q34311824 | BK channel activators and their therapeutic perspectives |
| Q28217424 | BMS-204352: a potassium channel opener developed for the treatment of stroke |
| Q28209314 | Barttin is a Cl- channel beta-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion |
| Q48826894 | Benign neonatal convulsions and spontaneous network activity in the developing brain: is there a link? |
| Q42424886 | Bimodal effects of the Kv7 channel activator retigabine on vascular K+ currents |
| Q48831806 | C-terminal interaction of KCNQ2 and KCNQ3 K+ channels |
| Q42694899 | Ca(2+)-Calmodulin and PIP2 interactions at the proximal C-terminus of Kv7 channels |
| Q28283065 | Ca(2+)-activated K+ channels: molecular determinants and function of the SK family |
| Q36786260 | Ca2+ signaling in the inner ear. |
| Q37344005 | Calmodulin activation limits the rate of KCNQ2 K+ channel exit from the endoplasmic reticulum. |
| Q44697458 | Calmodulin binding to M-type K+ channels assayed by TIRF/FRET in living cells |
| Q36447189 | Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels |
| Q90322241 | Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions |
| Q28566084 | Catalytic mechanism and substrate specificity of the beta-subunit of the voltage-gated potassium channel |
| Q78033790 | Cause for excite-M-ent in adrenal chromaffin cells |
| Q30497891 | Cellular and Molecular Mechanisms of Autosomal Dominant Form of Progressive Hearing Loss, DFNA2 |
| Q47650641 | Centipedes subdue giant prey by blocking KCNQ channels |
| Q39441418 | Chansporter complexes in cell signaling |
| Q35593089 | Characteristics and molecular basis of celecoxib modulation on K(v)7 potassium channels |
| Q24674102 | Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cells |
| Q36216300 | Chloride channel diseases resulting from impaired transepithelial transport or vesicular function |
| Q47918022 | Cholinergic control of ventral surface chemoreceptors involves Gq/inositol 1,4,5-trisphosphate-mediated inhibition of KCNQ channels |
| Q46644376 | Cholinergic suppression of KCNQ channel currents enhances excitability of striatal medium spiny neurons. |
| Q39480524 | Clinical and genetic features of 13 Spanish patients with KCNQ2 mutations. |
| Q36144410 | Clinical utility, safety, and tolerability of ezogabine (retigabine) in the treatment of epilepsy |
| Q34343185 | Clustered K+ channel complexes in axons |
| Q38371584 | Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel |
| Q61798984 | Cold acclimation via the KQT-2 potassium channel is modulated by oxygen in |
| Q27015827 | Comparative approaches to the study of physiology: Drosophila as a physiological tool. |
| Q24813729 | Computational identification of residues that modulate voltage sensitivity of voltage-gated potassium channels |
| Q37698178 | Conditional deletions of epilepsy-associated KCNQ2 and KCNQ3 channels from cerebral cortex cause differential effects on neuronal excitability |
| Q45194025 | Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior. |
| Q100558897 | Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR |
| Q44259602 | Congenital hearing loss. |
| Q40114576 | Contribution of KCNQ1 to the regulatory volume decrease in the human mammary epithelial cell line MCF-7. |
| Q35326586 | Contributions of Kv7-mediated potassium current to sub- and suprathreshold responses of rat layer II/III neocortical pyramidal neurons. |
| Q30465622 | Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase |
| Q28580624 | Coordinated signal integration at the M-type potassium channel upon muscarinic stimulation |
| Q36957011 | Coupling of L-type Ca2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity. |
| Q27657087 | Crystal structure of a trimeric form of the KV7.1 (KCNQ1) A-domain tail coiled-coil reveals structural plasticity and context dependent changes in a putative coiled-coil trimerization motif |
| Q96303145 | Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy in vivo |
| Q97644328 | Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels |
| Q38973882 | DNA methylation and expression of KCNQ3 in bipolar disorder. |
| Q29994691 | DV21 decreases excitability of cortical pyramidal neurons and acts in epilepsy |
| Q34125574 | Deafness and renal tubular acidosis in mice lacking the K-Cl co-transporter Kcc4. |
| Q44489167 | Degeneration of sensory outer hair cells following pharmacological blockade of cochlear KCNQ channels in the adult guinea pig. |
| Q38784550 | Differential Regulation of PI(4,5)P2 Sensitivity of Kv7.2 and Kv7.3 Channels by Calmodulin. |
| Q35633367 | Differential effects of Kv7 (M-) channels on synaptic integration in distinct subcellular compartments of rat hippocampal pyramidal neurons |
| Q37415814 | Differential effects of selective cyclooxygenase-2 inhibitors on vascular smooth muscle ion channels may account for differences in cardiovascular risk profiles. |
| Q42484960 | Differential expression of KCNQ4 in inner hair cells and sensory neurons is the basis of progressive high-frequency hearing loss. |
| Q46551024 | Direct in vivo imaging of essential bioinorganics in Caenorhabditis elegans |
| Q33401229 | Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes |
| Q42027335 | Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels. |
| Q38295716 | Distribution of M-channel subunits KCNQ2 and KCNQ3 in rat hippocampus |
| Q24675330 | Diverse mechanisms of antiepileptic drugs in the development pipeline |
| Q48342074 | Dorsoventral differences in Kv7/M-current and its impact on resonance, temporal summation and excitability in rat hippocampal pyramidal cells |
| Q36421000 | Drosophila aging 2006/2007 |
| Q34819187 | Drosophila as a model to study cardiac aging |
| Q44196345 | Drosophila ortholog of succinyl-CoA synthetase {beta} subunit: a novel modulator of Drosophila KCNQ channels |
| Q26765022 | Drosophila tools and assays for the study of human diseases |
| Q36507791 | Dynamics of Phosphoinositide-Dependent Signaling in Sympathetic Neurons. |
| Q41294377 | Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7.2 and Kv7.3 potassium channel subunits. |
| Q34726613 | Effect of the new antiepileptic drug retigabine in a rodent model of mania |
| Q34972352 | Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents |
| Q46857416 | Effects of retigabine on the neurodegeneration and extracellular glutamate changes induced by 4-aminopyridine in rat hippocampus in vivo |
| Q37302567 | Efficacy of retigabine in adjunctive treatment of partial onset seizures in adults |
| Q26771354 | Electrical resonance with voltage-gated ion channels: perspectives from biophysical mechanisms and neural electrophysiology |
| Q24634301 | Electrogenic tuning of the axon initial segment |
| Q35545042 | Electrophysiological and functional effects of the KCNQ channel blocker XE991 on murine portal vein smooth muscle cells |
| Q46903826 | Electrophysiological and molecular analysis of Kv7/KCNQ potassium channels in the inferior colliculus of adult guinea pig. |
| Q33622097 | Electrostatic tuning of cellular excitability |
| Q51074041 | Endoplasmic reticulum retention of KCNQ2 potassium channel mutants following temperature elevation. |
| Q43071251 | Enhancing m currents: a way out for neuropathic pain? |
| Q90711493 | Epilepsy-associated mutations in the voltage sensor of KCNQ3 affect voltage dependence of channel opening |
| Q36377765 | Epilepsy: a review of selected clinical syndromes and advances in basic science |
| Q46897469 | Epileptiform activity induced by pharmacologic reduction of M-current in the developing hippocampus in vitro |
| Q89081838 | Evaluating the pathogenic potential of genes with de novo variants in epileptic encephalopathies |
| Q46208968 | Expression and function of KCNQ channels in larval zebrafish |
| Q34449702 | Expression and function of the K+ channel KCNQ genes in human arteries. |
| Q30498039 | Expression and localization of K channels KCNQ2 and KCNQ3 in the mammalian cochlea |
| Q34132184 | Expression of a calmodulin-binding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability |
| Q30555468 | Extending the KCNQ2 encephalopathy spectrum: clinical and neuroimaging findings in 17 patients |
| Q36436699 | External barium affects the gating of KCNQ1 potassium channels and produces a pore block via two discrete sites |
| Q34996454 | Facilitating an understanding of integrative physiology: emphasis on the composition of body fluid compartments. |
| Q104496505 | Familial neonatal seizures caused by the Kv7.3 selectivity filter mutation T313I |
| Q36428969 | From molecule to malady |
| Q28539924 | From pan-reactive KV7 channel opener to subtype selective opener/inhibitor by addition of a methyl group |
| Q35145708 | Fruit flies in biomedical research. |
| Q30466258 | Function and mechanism of axonal targeting of voltage-sensitive potassium channels |
| Q44492027 | Functional coupling between heterologously expressed dopamine D(2) receptors and KCNQ channels |
| Q37101703 | Functional expression of KCNQ (Kv7) channels in guinea pig bladder smooth muscle and their contribution to spontaneous activity |
| Q28238047 | Functional significance of K+ channel β-subunit KCNE3 in auditory neurons |
| Q36691221 | Functional significance of axonal Kv7 channels in hippocampal pyramidal neurons |
| Q28545940 | Genetic Polymorphisms Associated with Hearing Threshold Shift in Subjects during First Encounter with Occupational Impulse Noise |
| Q35945999 | Genetic control of heart function and aging in Drosophila |
| Q55645201 | Genetic etiologies of the electrical status epilepticus during slow wave sleep: systematic review. |
| Q30453431 | Genetics of hearing loss: focus on DFNA2. |
| Q92995749 | Genome wide association study of incomplete hippocampal inversion in adolescents |
| Q104079518 | Genome-wide DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia in the Chinese Han population |
| Q93197571 | Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss |
| Q37996815 | HCN and KV7 (M-) channels as targets for epilepsy treatment |
| Q37171671 | HCN hyperpolarization-activated cation channels inhibit EPSPs by interactions with M-type K(+) channels |
| Q42618413 | Hair Cell Transduction, Tuning, and Synaptic Transmission in the Mammalian Cochlea |
| Q36506405 | Hair cells--beyond the transducer |
| Q35102994 | Heartburn: cardiac potassium channels involved in parietal cell acid secretion |
| Q41813389 | Hepatic encephalopathy: An approach to its multiple pathophysiological features |
| Q37617404 | Heteromeric Kv7.2/7.3 channels differentially regulate action potential initiation and conduction in neocortical myelinated axons. |
| Q36476692 | Hippocalcin and KCNQ channels contribute to the kinetics of the slow afterhyperpolarization |
| Q37710852 | Homeostatic regulation of neuronal excitability by K(+) channels in normal and diseased brains |
| Q30485406 | Homomeric and heteromeric assembly of KCNQ (Kv7) K+ channels assayed by total internal reflection fluorescence/fluorescence resonance energy transfer and patch clamp analysis |
| Q41836911 | Human induced pluripotent stem cell derived neurons as a model for Williams-Beuren syndrome |
| Q37286419 | Hyperpolarization activated cyclic-nucleotide gated (HCN) channels in developing neuronal networks |
| Q38968792 | Hysteresis in voltage-gated channels |
| Q45183609 | Impaired permeability to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafness |
| Q37060221 | Impaired surface expression and conductance of the KCNQ4 channel lead to sensorineural hearing loss |
| Q37223721 | In silico investigations on functional and haplotype tag SNPs associated with congenital long QT syndromes (LQTSs) |
| Q28066803 | In-Depth Study of the Interaction, Sensitivity, and Gating Modulation by PUFAs on K+ Channels; Interaction and New Targets |
| Q24676507 | Inactivation as a new regulatory mechanism for neuronal Kv7 channels |
| Q97545711 | Inactivation in the potassium channel KcsA |
| Q46985574 | Infantile spasms as an epileptic feature of DEND syndrome associated with an activating mutation in the potassium adenosine triphosphate (ATP) channel, Kir6.2. |
| Q44193330 | Inhibition of K+ currents of outer hair cells in guinea pig cochlea by fluoxetine |
| Q97644176 | Inhibition of M/Kv7 Currents Contributes to Chloroquine-Induced Itch in Mice |
| Q37084254 | Interaction of P2 purinergic receptors with cellular macromolecules. |
| Q27307787 | Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3. |
| Q48201175 | Involvement of KCNQ2 subunits in [3H]dopamine release triggered by depolarization and pre-synaptic muscarinic receptor activation from rat striatal synaptosomes. |
| Q38795017 | Ion Channel Genes and Epilepsy: Functional Alteration, Pathogenic Potential, and Mechanism of Epilepsy |
| Q64099966 | Ion Channels Involved in Substance P-Mediated Nociception and Antinociception |
| Q21145023 | Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordates |
| Q37562039 | Ion channel-transporter interactions |
| Q28189601 | Ion channels and epilepsy |
| Q47852103 | Ionic mechanisms of autorhythmic firing in rat cerebellar Golgi cells |
| Q28564958 | K(V)7/KCNQ channels are functionally expressed in oligodendrocyte progenitor cells |
| Q42637406 | K(v) 7 (KCNQ) channel openers normalize central 2-deoxyglucose uptake in a mouse model of mania and increase prefrontal cortical and hippocampal serine-9 phosphorylation levels of GSK3β. |
| Q92045666 | K+ Accumulation and Clearance in the Calyx Synaptic Cleft of Type I Mouse Vestibular Hair Cells |
| Q33327366 | KCNE1 constrains the voltage sensor of Kv7.1 K+ channels |
| Q24642042 | KCNE4 is an inhibitory subunit to the KCNQ1 channel |
| Q37629298 | KCNQ (Kv7) potassium channel activators as bronchodilators: combination with a β2-adrenergic agonist enhances relaxation of rat airways |
| Q38915867 | KCNQ Potassium Channels Modulate Sensitivity of Skin Down-hair (D-hair) Mechanoreceptors |
| Q46983632 | KCNQ channels mediate IKs, a slow K+ current regulating excitability in the rat node of Ranvier |
| Q24681227 | KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging |
| Q26774667 | KCNQ potassium channels in sensory system and neural circuits |
| Q34305841 | KCNQ potassium channels: physiology, pathophysiology, and pharmacology |
| Q39956328 | KCNQ-encoded channels regulate Na+ transport across H441 lung epithelial cells |
| Q31157254 | KCNQ-like potassium channels in Caenorhabditis elegans. Conserved properties and modulation |
| Q44894502 | KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons. |
| Q44540560 | KCNQ/M currents in sensory neurons: significance for pain therapy. |
| Q79733814 | KCNQ/M-currents contribute to the resting membrane potential in rat visceral sensory neurons |
| Q42520564 | KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein |
| Q48830157 | KCNQ1 channels sense small changes in cell volume |
| Q35503231 | KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue. |
| Q44755361 | KCNQ2 is a nodal K+ channel. |
| Q50459046 | KCNQ2/3 channel agonist flupirtine reduces cocaine place preference in rats |
| Q50432426 | KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man. |
| Q48345552 | KCNQ5 K(+) channels control hippocampal synaptic inhibition and fast network oscillations |
| Q35543305 | KCNQ5/K(v)7.5 potassium channel expression and subcellular localization in primate retinal pigment epithelium and neural retina |
| Q37733383 | KV7 channelopathies |
| Q30438624 | Kcnq1-5 (Kv7.1-5) potassium channel expression in the adult zebrafish |
| Q51532244 | Kv7 (KCNQ) channel openers induce hypothermia in the mouse |
| Q80994885 | Kv7 (KCNQ) potassium channels that are mutated in human diseases |
| Q57921518 | Kv7 channels are upregulated during striatal neuron development and promote maturation of human iPSC-derived neurons |
| Q51090363 | Kv7 channels regulate pairwise spiking covariability in health and disease. |
| Q37049822 | Kv7 channels: interaction with dopaminergic and serotonergic neurotransmission in the CNS. |
| Q35950205 | Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy. |
| Q34251255 | Kv7-type channel currents in spiral ganglion neurons: involvement in sensorineural hearing loss |
| Q35597965 | Kv7.2 regulates the function of peripheral sensory neurons |
| Q92535242 | Kv7.4 Channel Contribute to Projection-Specific Auto-Inhibition of Dopamine Neurons in the Ventral Tegmental Area |
| Q36618785 | Kv7.5 Potassium Channel Subunits Are the Primary Targets for PKA-Dependent Enhancement of Vascular Smooth Muscle Kv7 Currents. |
| Q35629778 | Kv7.5 is the primary Kv7 subunit expressed in C-fibers |
| Q46487845 | Kv7/KCNQ/M and HCN/h, but not KCa2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells. |
| Q58694694 | Lack of correlation between surface expression and currents in epileptogenic AB-calmodulin binding domain Kv7.2 potassium channel mutants |
| Q44765967 | Linkage of bipolar affective disorder on chromosome 8q24: follow-up and parametric analysis |
| Q28190825 | Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation |
| Q46359359 | Low expression of Kv7/M channels facilitates intrinsic and network bursting in the developing rat hippocampus |
| Q44737230 | M channels containing KCNQ2 subunits modulate norepinephrine, aspartate, and GABA release from hippocampal nerve terminals. |
| Q34775744 | M current mystery messenger revealed? |
| Q96304623 | M-Current Suppression, Seizures and Lipid Metabolism: A Potential Link Between Neuronal Kv7 Channel Regulation and Dietary Therapies for Epilepsy |
| Q42508623 | M-channels (Kv7/KCNQ channels) that regulate synaptic integration, excitability, and spike pattern of CA1 pyramidal cells are located in the perisomatic region. |
| Q47433940 | M-current inhibition rapidly induces a unique CK2-dependent plasticity of the axon initial segment |
| Q27332374 | M-current preservation contributes to anticonvulsant effects of valproic acid. |
| Q38628600 | M-type K(+) channels in peripheral nociceptive pathways. |
| Q30455624 | M-type potassium channels modulate Schaffer collateral-CA1 glutamatergic synaptic transmission |
| Q34762259 | Made for “anchorin”: Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons |
| Q28290639 | Major channels involved in neuropsychiatric disorders and therapeutic perspectives |
| Q36442698 | Maternal immune activation produces neonatal excitability defects in offspring hippocampal neurons from pregnant rats treated with poly I:C |
| Q38044382 | Mechanism of electromechanical coupling in voltage-gated potassium channels |
| Q38647500 | Mechanisms of Persistent Activity in Cortical Circuits: Possible Neural Substrates for Working Memory |
| Q64079484 | Mechanisms of cannabinoid CB receptor-mediated reduction of dopamine neuronal excitability in mouse ventral tegmental area |
| Q41939192 | Mechanisms underlying modulation of neuronal KCNQ2/KCNQ3 potassium channels by extracellular protons |
| Q28594332 | Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness |
| Q36164522 | Migration of PIP2 lipids on voltage-gated potassium channel surface influences channel deactivation |
| Q35120756 | Mitochondrial potassium channels and uncoupling proteins in synaptic plasticity and neuronal cell death |
| Q36760412 | Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction |
| Q36395041 | Mixed-mode oscillations in pyramidal neurons under antiepileptic drug conditions |
| Q37039299 | Modification of K+ channel-drug interactions by ancillary subunits. |
| Q40143169 | Modulation of ERG channels by XE991. |
| Q97420308 | Modulation of KV7 Channel Deactivation by PI(4,5)P2 |
| Q38958968 | Modulation of Kv7 channels and excitability in the brain |
| Q90318650 | Molecular Mechanisms and Structural Basis of Retigabine Analogues in Regulating KCNQ2 Channel |
| Q46906697 | Molecular analyses of KCNQ1-5 potassium channel mRNAs in rat and guinea pig inner ears: expression, cloning, and alternative splicing. |
| Q37264515 | Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles |
| Q98945191 | Molecular basis for ligand activation of the human KCNQ2 channel |
| Q44161111 | Molecular correlates of the M-current in cultured rat hippocampal neurons |
| Q46497180 | Molecular determinants of KCNQ (Kv7) K+ channel sensitivity to the anticonvulsant retigabine. |
| Q41590646 | Molecular expression and pharmacological identification of a role for K(v)7 channels in murine vascular reactivity |
| Q28081514 | Molecular underpinnings of ventral surface chemoreceptor function: focus on KCNQ channels |
| Q36243931 | Motoneurones "learn" and "forget" physical activity |
| Q57023903 | Mutations in KCNK4 that Affect Gating Cause a Recognizable Neurodevelopmental Syndrome |
| Q24555140 | Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel |
| Q36667893 | NGF inhibits M/KCNQ currents and selectively alters neuronal excitability in subsets of sympathetic neurons depending on their M/KCNQ current background |
| Q35096118 | Natural patterns of neural activity: how physiological mechanisms are orchestrated to cope with real life. |
| Q36344256 | Neonatal epilepsy syndromes and GEFS+: mechanistic considerations |
| Q37073177 | Nervous system KV7 disorders: breakdown of a subthreshold brake |
| Q24644947 | Neural KCNQ (Kv7) channels |
| Q26798018 | Neuronal and Cardiovascular Potassium Channels as Therapeutic Drug Targets: Promise and Pitfalls |
| Q57816640 | Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system |
| Q47654383 | Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes |
| Q48772580 | Neutralization of a negative charge in the S1-S2 region of the KV7.2 (KCNQ2) channel affects voltage-dependent activation in neonatal epilepsy |
| Q35759329 | New and emerging pharmacological targets for neuropathic pain |
| Q37596531 | New tricks for old dogs: KCNQ expression and role in smooth muscle |
| Q44898858 | Newly developed blockers of the M-current do not reduce spike frequency adaptation in cultured mouse sympathetic neurons. |
| Q64912185 | Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability. |
| Q41910842 | Novel role of KCNQ2/3 channels in regulating neuronal cell viability |
| Q33975038 | Oxidative modulation of voltage-gated potassium channels |
| Q37135466 | P2Y receptors and pain transmission |
| Q44386912 | PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents |
| Q51798057 | PIP(2)-dependent inhibition of M-type (Kv7.2/7.3) potassium channels: direct on-line assessment of PIP(2) depletion by Gq-coupled receptors in single living neurons. |
| Q51102140 | PKC-dependent regulation of Kv7.5 channels by the bronchoconstrictor histamine in human airway smooth muscle cells. |
| Q33245065 | PP2A-Bgamma subunit and KCNQ2 K+ channels in bipolar disorder |
| Q42972474 | Participation of KCNQ (Kv7) potassium channels in myogenic control of cerebral arterial diameter |
| Q33691804 | Pathogenetic role of the deafness-related M34T mutation of Cx26. |
| Q30445995 | Pathogenic plasticity of Kv7.2/3 channel activity is essential for the induction of tinnitus |
| Q34464180 | Pathways modulating neural KCNQ/M (Kv7) potassium channels |
| Q33757330 | Peripheral KV7 channels regulate visceral sensory function in mouse and human colon. |
| Q34151496 | Persistent currents and discharge patterns in rat hindlimb motoneurons |
| Q97420402 | Pharmacological Manipulation of K v 7 Channels as a New Therapeutic Tool for Multiple Brain Disorders |
| Q41988993 | Pharmacology of currents underlying the different firing patterns of spinal sensory neurons and interneurons identified in vivo using multivariate analysis |
| Q57803432 | Phosphatidylinositol 4,5-bisphosphate (PIP2) regulates KCNQ3 K+ channels by interacting with four cytoplasmic channel domains |
| Q90049726 | Phosphoinositides: Regulators of Nervous System Function in Health and Disease |
| Q38824986 | Plasticity of the Axon Initial Segment: Fast and Slow Processes with Multiple Functional Roles |
| Q24545908 | Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains |
| Q36010897 | Pore determinants of KCNQ3 K+ current expression |
| Q36010857 | Pore helix-S6 interactions are critical in governing current amplitudes of KCNQ3 K+ channels |
| Q37311277 | Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. |
| Q38824328 | Potassium Channels in Epilepsy. |
| Q38966111 | Potassium channel gene associations with joint processing speed and white matter impairments in schizophrenia. |
| Q35911129 | Potassium channel subtypes as molecular targets for overactive bladder and other urological disorders |
| Q38062581 | Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives |
| Q38059092 | Potassium channels: a review of broadening therapeutic possibilities for neurological diseases |
| Q38151974 | Potassium channels: structures, diseases, and modulators |
| Q28205333 | Potassium leak channels and the KCNK family of two-P-domain subunits |
| Q30396439 | Potent KCNQ2/3-specific channel activator suppresses in vivo epileptic activity and prevents the development of tinnitus |
| Q28283022 | Potential mechanisms of sudden unexpected death in epilepsy |
| Q35000482 | Potential role of KCNQ/M-channels in regulating neuronal differentiation in mouse hippocampal and embryonic stem cell-derived neuronal cultures |
| Q51802961 | Pre- and postsynaptic activation of M-channels by a novel opener dampens neuronal firing and transmitter release. |
| Q27316607 | Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice |
| Q91867447 | Presynaptic Mechanisms and KCNQ Potassium Channels Modulate Opioid Depression of Respiratory Drive |
| Q35916542 | Probing the polygenic basis of cardiomyopathies in Drosophila |
| Q30445781 | Protein Phosphatase 2a and glycogen synthase kinase 3 signaling modulate prepulse inhibition of the acoustic startle response by altering cortical M-Type potassium channel activity |
| Q37201261 | Protein arginine methylation facilitates KCNQ channel-PIP2 interaction leading to seizure suppression |
| Q46716619 | Protein kinase C shifts the voltage dependence of KCNQ/M channels expressed in Xenopus oocytes |
| Q36777523 | Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1 |
| Q25257466 | Pulmonary vasoconstrictor action of KCNQ potassium channel blockers. |
| Q30492676 | Purinergic modulation of cochlear partition resistance and its effect on the endocochlear potential in the Guinea pig. |
| Q28215456 | Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel |
| Q42104441 | Rapid and efficient CRISPR/Cas9 gene inactivation in human neurons during human pluripotent stem cell differentiation and direct reprogramming |
| Q92756961 | Rare KCNQ4 variants found in public databases underlie impaired channel activity that may contribute to hearing impairment |
| Q90217319 | Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy |
| Q53070307 | Reduced excitability of gp130-deficient nociceptors is associated with increased voltage-gated potassium currents and Kcna4 channel upregulation. |
| Q30394930 | Regulation of KCNQ/Kv7 family voltage-gated K+ channels by lipids. |
| Q80065013 | Regulation of M(Kv7.2/7.3) channels in neurons by PIP(2) and products of PIP(2) hydrolysis: significance for receptor-mediated inhibition |
| Q48663756 | Regulation of neuronal M-channel gating in an isoform-specific manner: functional interplay between calmodulin and syntaxin 1A. |
| Q46412703 | Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels. |
| Q30622772 | Rescue of homeostatic regulation of striatal excitability and locomotor activity in a mouse model of Huntington's disease. |
| Q38154412 | Research advances in basic mechanisms of seizures and antiepileptic drug action |
| Q44376554 | Resting potential and submembrane calcium concentration of inner hair cells in the isolated mouse cochlea are set by KCNQ-type potassium channels. |
| Q42265492 | Restoration of ion channel function in deafness-causing KCNQ4 mutants by synthetic channel openers |
| Q36634324 | Retigabine holds KV7 channels open and stabilizes the resting potential |
| Q28550367 | Retigabine, a Kv7.2/Kv7.3-Channel Opener, Attenuates Drug-Induced Seizures in Knock-In Mice Harboring Kcnq2 Mutations |
| Q34333196 | Retigabine/Ezogabine, a KCNQ/K(V)7 channel opener: pharmacological and clinical data |
| Q34415600 | Retigabine: chemical synthesis to clinical application. |
| Q91940224 | Role of KCNQ potassium channels in stress-induced deficit of working memory |
| Q61764891 | Role of KCNQ2 and KCNQ3 genes in juvenile idiopathic epilepsy in Arabian foals |
| Q36688976 | Role of genetics in the diagnosis and treatment of epilepsy |
| Q46398878 | Roles of alternative splicing in the functional properties of inner ear-specific KCNQ4 channels |
| Q44213055 | Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks. |
| Q51455230 | Selective activation of vascular Kv 7.4/Kv 7.5 K+ channels by fasudil contributes to its vasorelaxant effect. |
| Q48171841 | Selective cochlear degeneration in mice lacking the F-box protein, Fbx2, a glycoprotein-specific ubiquitin ligase subunit. |
| Q33493069 | Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity |
| Q47704907 | Selective targeting of M-type potassium Kv 7.4 channels demonstrates their key role in the regulation of dopaminergic neuronal excitability and depression-like behaviour. |
| Q36405047 | Signaling protein complexes associated with neuronal ion channels |
| Q40205198 | Somatodendritic Kv7/KCNQ/M channels control interspike interval in hippocampal interneurons. |
| Q28579627 | Stoichiometry of expressed KCNQ2/KCNQ3 potassium channels and subunit composition of native ganglionic M channels deduced from block by tetraethylammonium |
| Q49790725 | Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel |
| Q50650720 | Structural determinants of M-type KCNQ (Kv7) K+ channel assembly. |
| Q40275976 | Structural effects of an LQT-3 mutation on heart Na+ channel gating |
| Q24619681 | Structural insight into KCNQ (Kv7) channel assembly and channelopathy |
| Q33911083 | Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin |
| Q27675217 | Structure of a Ca2+/CaM:Kv7.4 (KCNQ4) B-Helix Complex Provides Insight into M Current Modulation |
| Q44270181 | Subunit-specific modulation of KCNQ potassium channels by Src tyrosine kinase. |
| Q34463498 | Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker |
| Q51738570 | Synthesis and Evaluation of Potent KCNQ2/3-Specific Channel Activators. |
| Q35006192 | Tamoxifen inhibition of kv7.2/kv7.3 channels |
| Q28076907 | Targeting Prefrontal Cortical Systems for Drug Development: Potential Therapies for Cognitive Disorders |
| Q39424199 | Targeting of Kv7.5 (KCNQ5)/KCNE channels to surface microdomains of cell membranes. |
| Q34100500 | Targeting the voltage sensor of Kv7.2 voltage-gated K+ channels with a new gating-modifier |
| Q48664983 | Temperature and pharmacological rescue of a folding-defective, dominant-negative KV 7.2 mutation associated with neonatal seizures |
| Q42594000 | Thalamic Kv 7 channels: pharmacological properties and activity control during noxious signal processing |
| Q37064702 | The C-terminus of Kv7 channels: a multifunctional module. |
| Q30497430 | The KATP Channel Activator Diazoxide Ameliorates Amyloid-β and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer's Disease |
| Q24305236 | The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction |
| Q33933223 | The KCNQ5 potassium channel mediates a component of the afterhyperpolarization current in mouse hippocampus |
| Q47098209 | The Kv7 Channel and Cardiovascular Risk Factors |
| Q39396477 | The Kv7.2/Kv7.3 heterotetramer assembles with a random subunit arrangement |
| Q48404998 | The M-current inhibitor XE991 decreases the stimulation threshold for long-term synaptic plasticity in healthy mice and in models of cognitive disease. |
| Q37445738 | The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes |
| Q35874979 | The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K+ Current Amplitudes by Controlling Channel Trafficking |
| Q36548403 | The Sensorless Pore Module of Voltage-gated K+ Channel Family 7 Embodies the Target Site for the Anticonvulsant Retigabine |
| Q34359558 | The Specific Slow Afterhyperpolarization Inhibitor UCL2077 Is a Subtype-Selective Blocker of the Epilepsy Associated KCNQ Channels |
| Q36678567 | The Voltage Activation of Cortical KCNQ Channels Depends on Global PIP2 Levels |
| Q28472214 | The acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytes |
| Q44297459 | The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic pain |
| Q35550542 | The biology of epilepsy genes |
| Q36933248 | The cellular building blocks of breathing |
| Q30460358 | The cochlear CRF signaling systems and their mechanisms of action in modulating cochlear sensitivity and protection against trauma |
| Q37813146 | The evolving understanding of the analgesic mechanism of action of flupirtine |
| Q35198044 | The genetics of human epilepsy |
| Q91576416 | The impact of hyperpolarization-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium KCNQ/Kv7 channels on primary microglia function |
| Q34768788 | The interface of preclinical evaluation with clinical testing of antiepileptic drugs: role of pharmacogenomics and pharmacogenetics |
| Q37973378 | The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy |
| Q34649239 | The neuronal channelopathies |
| Q48630808 | The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current |
| Q36675813 | The new KCNQ2 activator 4-Chlor-N-(6-chlor-pyridin-3-yl)-benzamid displays anticonvulsant potential. |
| Q39632547 | The pan-Kv7 (KCNQ) Channel Opener Retigabine Inhibits Striatal Excitability by Direct Action on Striatal Neurons In Vivo |
| Q51566365 | The pharmacological effect of positive KCNQ (Kv7) modulators on dopamine release from striatal slices. |
| Q46969546 | The potassium channel KCNQ5/Kv7.5 is localized in synaptic endings of auditory brainstem nuclei of the rat. |
| Q36299677 | The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes |
| Q40379431 | The role of genetics and ethnicity in epilepsy management |
| Q64084428 | The subthreshold-active K7 current regulates neurotransmission by limiting spike-induced Ca influx in hippocampal mossy fiber synaptic terminals |
| Q35593939 | The therapeutic potential of neuronal KCNQ channel modulators |
| Q37994720 | The urinary safety profile and secondary renal effects of retigabine (ezogabine): a first-in-class antiepileptic drug that targets KCNQ (K(v)7) potassium channels |
| Q40279082 | Theoretical investigation of the neuronal Na+ channel SCN1A: abnormal gating and epilepsy |
| Q48810175 | Three mechanisms underlie KCNQ2/3 heteromeric potassium M-channel potentiation. |
| Q39647545 | Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability |
| Q38646018 | Transmembrane allosteric energetics characterization for strong coupling between proton and potassium ion binding in the KcsA channel. |
| Q37346548 | Treatment with the Kv7 potassium channel activator flupirtine is beneficial in two independent mouse models of pulmonary hypertension |
| Q44249830 | Two forms of electrical resonance at theta frequencies, generated by M-current, h-current and persistent Na+ current in rat hippocampal pyramidal cells |
| Q28364994 | Two open states and rate-limiting gating steps revealed by intracellular Na+ block of human KCNQ1 and KCNQ1/KCNE1 K+ channels |
| Q33905030 | Unraveling monogenic channelopathies and their implications for complex polygenic disease |
| Q50453648 | Update on physiology and pathophysiology of the inner ear: pathomechanisms of sensorineural hearing loss |
| Q36514114 | Vascular KCNQ (Kv7) potassium channels as common signaling intermediates and therapeutic targets in cerebral vasospasm. |
| Q41538933 | Vascular KCNQ channels in humans: the sub-threshold brake that regulates vascular tone? |
| Q37001792 | Vascular KCNQ potassium channels as novel targets for the control of mesenteric artery constriction by vasopressin, based on studies in single cells, pressurized arteries, and in vivo measurements of mesenteric vascular resistance. |
| Q40501013 | Ventral otic cell lines as developmental models of auditory epithelial and neural precursors |
| Q36725074 | Vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models |
| Q34390785 | Voltage-gated potassium channels at the crossroads of neuronal function, ischemic tolerance, and neurodegeneration |
| Q37108106 | Water and ion channels: crucial in the initiation and progression of apoptosis in central nervous system? |
| Q44400605 | XE991 and Linopirdine Are State-Dependent Inhibitors for Kv7/KCNQ Channels that Favor Activated Single Subunits |
| Q40145551 | Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants |
| Q33824948 | [EXPRESS] Ion channels and neuronal hyperexcitability in chemotherapy-induced peripheral neuropathy; cause and effect? |
| Q84594452 | [New developments in epileptogenesis and therapeutic perspectives] |
| Q27008078 | hERG channel function: beyond long QT |
| Q90131522 | β-Secretase BACE1 Is Required for Normal Cochlear Function |
| Q48221664 | β-Secretase BACE1 regulates hippocampal and reconstituted M-currents in a β-subunit-like fashion. |