Focal adhesion kinase can play unique and opposing roles in regulating the morphology of differentiating oligodendrocytes

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Focal adhesion kinase can play unique and opposing roles in regulating the morphology of differentiating oligodendrocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1471-4159.2010.06926.X
P932PMC publication ID2939935
P698PubMed publication ID20649846
P5875ResearchGate publication ID45280921

P2093author name stringBabette Fuss
Audrey D Lafrenaye
P2860cites workIntegrin-regulated FAK-Src signaling in normal and cancer cellsQ24300271
Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillinQ24301607
pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesionsQ24561464
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelinationQ24657511
Dynamic regulation of integrin activation by intracellular and extracellular signals controls oligodendrocyte morphologyQ24812455
Integrin signalingQ28142010
Focal adhesion kinase signaling activities and their implications in the control of cell survival and motilityQ28191559
Signaling through focal adhesion kinaseQ28198051
WAVE1 and regulation of actin nucleation in myelinationQ28250992
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migrationQ28369093
Microtubule deacetylases, SirT2 and HDAC6, in the nervous systemQ28510189
Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelinationQ28568812
Integrin-linked kinase is required for laminin-2-induced oligodendrocyte cell spreading and CNS myelinationQ28570846
Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelinationQ28577221
Cloning of focal adhesion kinase, pp125FAK, from rat brain reveals multiple transcripts with different patterns of expressionQ28577982
Synthesis of gangliosides by cultured oligodendrocytesQ70978936
Oligodendrocyte progenitors are generated throughout the embryonic mouse brain, but differentiate in restricted fociQ71192818
Differential expression of gangliosides and galactolipids in fetal human oligodendrocytes and astrocytes in cultureQ71525686
Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and FynQ71593826
Focal adhesion kinase in the brain: novel subcellular localization and specific regulation by Fyn tyrosine kinase in mutant miceQ71706890
Progressive remodeling of the oligodendrocyte process arbor during myelinogenesisQ71765636
Rat oligodendroglia express c-met and focal adhesion kinase, protein tyrosine kinases implicated in regulating epithelial cell motilityQ73439485
Characterization of a putative novel type of oligodendrocyte in cultures from rat spinal cordQ74012705
Molecular heterogeneity of oligodendrocytes in chicken white matterQ77988300
Astrocyte-associated fibronectin is critical for axonal regeneration in adult white matterQ80889515
Netrin 1 and Dcc regulate oligodendrocyte process branching and membrane extension via Fyn and RhoAQ57041642
Alteration of the extracellular matrix interferes with raft association of neurofascin in oligodendrocytes. Potential significance for multiple sclerosis?Q57361218
Focal Adhesion Kinase in Rat Central Nervous SystemQ58191988
Phosphodiesterase-Ialpha/autotaxin: a counteradhesive protein expressed by oligodendrocytes during onset of myelinationQ28578944
Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte developmentQ28582937
WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelinationQ28585142
Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activityQ28585169
Control of axonal branching and synapse formation by focal adhesion kinaseQ28587436
EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activationQ28592406
Focal adhesion kinase: the first ten yearsQ28609173
A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and functionQ29547320
Focal adhesion kinase: in command and control of cell motilityQ29615192
Environmental sensing through focal adhesionsQ29615211
Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.Q30194623
Cellular characterization of a novel focal adhesion kinase inhibitorQ30443304
Myosin II has distinct functions in PNS and CNS myelin sheath formationQ30483610
Oligodendrocyte development and myelin biogenesis: parsing out the roles of glycosphingolipidsQ33787612
Single or multiple oligodendroglial lineages: a controversyQ33811069
Biology of oligodendrocyte and myelin in the mammalian central nervous systemQ33939997
The oligodendrocyte and its many cellular processesQ34290907
Selective differentiation of neural progenitor cells by high-epitope density nanofibersQ34291910
beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration.Q34356438
Process extension and myelin sheet formation in maturing oligodendrocytesQ34361140
Cell death and control of cell survival in the oligodendrocyte lineageQ34460930
Functional genomic analysis of oligodendrocyte differentiation.Q34576676
Fibronectin in multiple sclerosis lesionsQ35817604
The interplay between Src and integrins in normal and tumor biologyQ35920891
Integrin-growth factor interactions as regulators of oligodendroglial development and functionQ35971762
Human diseases reveal novel roles for neural lamininsQ36206877
Emergence of three myelin proteins in oligodendrocytes cultured without neuronsQ36214316
Morphological differentiation of oligodendrocytes requires activation of Fyn tyrosine kinaseQ36256520
PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motilityQ36404901
Phosphodiesterase-Ialpha/autotaxin's MORFO domain regulates oligodendroglial process network formation and focal adhesion organizationQ36494535
Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.Q36527182
New concepts regarding focal adhesion kinase promotion of cell migration and proliferationQ36528648
Cell-matrix adhesionQ36902965
The extracellular matrix in multiple sclerosis pathologyQ36940050
The cytoskeleton in oligodendrocytes. Microtubule dynamics in health and diseaseQ37023835
Focal adhesion kinase versus p53: apoptosis or survival?Q37168898
Adhesion molecules in the regulation of CNS myelination.Q37218958
FERM control of FAK function: implications for cancer therapy.Q37234240
Integrin-mediated axoglial interactions initiate myelination in the central nervous systemQ37263985
Angiopoietin-1 induces neurite outgrowth of PC12 cells in a Tie2-independent, beta1-integrin-dependent mannerQ37314658
Focal adhesion kinase (FAK): A regulator of CNS myelinationQ37384287
Autophosphorylation-independent and -dependent functions of focal adhesion kinase during developmentQ37454238
Laminin alters fyn regulatory mechanisms and promotes oligodendrocyte developmentQ37461843
Role of the oligodendroglial cytoskeleton in differentiation and myelinationQ37489705
Cellular functions of FAK kinases: insight into molecular mechanisms and novel functionsQ37717830
Molecular biology of myelin proteins from the central nervous systemQ38189000
A role for the MAPK/ERK pathway in oligodendroglial differentiation in vitro: stage specific effects on cell branchingQ39803937
Morphological changes do not reflect biochemical and functional differentiation in OLN-93 oligodendroglial cellsQ39826085
SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signalingQ39961268
Focal adhesion kinase regulates laminin-induced oligodendroglial process outgrowthQ40055734
N-WASP regulates extension of filopodia and processes by oligodendrocyte progenitors, oligodendrocytes, and Schwann cells-implications for axon ensheathment at myelinationQ40150333
Fibronectin impedes "myelin" sheet-directed flow in oligodendrocytes: a role for a beta 1 integrin-mediated PKC signaling pathway in vesicular traffickingQ40239220
Distinct FAK-Src activation events promote alpha5beta1 and alpha4beta1 integrin-stimulated neuroblastoma cell motility.Q41342957
Signaling through focal adhesion kinaseQ41359146
Beta1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth.Q42136039
Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous systemQ42799087
Up-regulation of oligodendrocyte precursor cell alphaV integrin and its extracellular ligands during central nervous system remyelination.Q43279305
Cytoskeletal reorganization during the formation of oligodendrocyte processes and branchesQ43581929
Expression of dominant-negative and chimeric subunits reveals an essential role for beta1 integrin during myelinationQ43686017
CNS integrins switch growth factor signalling to promote target-dependent survivalQ44179357
Localization of focal adhesion kinase isoforms in cells of the central nervous systemQ44341097
Multiple and novel specificities of monoclonal antibodies O1, O4, and R-mAb used in the analysis of oligodendrocyte developmentQ44623340
Signaling from integrins to Fyn to Rho family GTPases regulates morphologic differentiation of oligodendrocytes.Q44684981
Phosphodiesterase-I alpha/autotaxin controls cytoskeletal organization and FAK phosphorylation during myelination.Q44905812
Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activityQ45023686
Molecular network of the comprehensive multiple sclerosis brain-lesion proteome.Q46038884
Alternatively spliced focal adhesion kinase in rat brain with increased autophosphorylation activityQ48043166
Compartmentation of Fyn kinase with glycosylphosphatidylinositol-anchored molecules in oligodendrocytes facilitates kinase activation during myelinationQ48101123
The proneural gene Mash1 specifies an early population of telencephalic oligodendrocytes.Q48197899
Mapping regions of the beta1 integrin cytoplasmic domain involved in migration and survival in primary oligodendrocyte precursors using cell-permeable homeopeptidesQ48206576
The timely expression of myelin basic protein gene in cultured rat brain oligodendrocytes is independent of continuous neuronal influences.Q48444004
Integrins mediate a neuronal survival signal for oligodendrocytesQ48564652
Dominant-negative beta1 integrin mice have region-specific myelin defects accompanied by alterations in MAPK activityQ48598079
Biochemical subtypes of oligodendrocyte in the anterior medullary velum of the rat as revealed by the monoclonal antibody ripQ48790068
CNS neuronal focal adhesion kinase forms clusters that co-localize with vinculinQ48860220
Transcription factor co-expression patterns indicate heterogeneity of oligodendroglial subpopulations in adult spinal cord.Q52018890
Laminin-2/integrin interactions enhance myelin membrane formation by oligodendrocytes.Q52172922
Expression of alpha vbeta3 and alpha vbeta8 integrins during oligodendrocyte precursor differentiation in the presence and absence of axons.Q52191560
A developmental analysis of oligodendroglial integrins in primary cells: changes in alpha v-associated beta subunits during differentiation.Q52212750
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectoligodendrocyteQ916698
P1104number of pages14
P304page(s)269-282
P577publication date2010-08-19
P1433published inJournal of NeurochemistryQ6295643
P1476titleFocal adhesion kinase can play unique and opposing roles in regulating the morphology of differentiating oligodendrocytes
P478volume115

Reverse relations

cites work (P2860)
Q33934115Activation of sodium-dependent glutamate transporters regulates the morphological aspects of oligodendrocyte maturation via signaling through calcium/calmodulin-dependent kinase IIβ's actin-binding/-stabilizing domain
Q64110856Astrocyte Mechano-Activation by High-Rate Overpressure Involves Alterations in Structural and Junctional Proteins
Q39233765Axonal Regulation of Central Nervous System Myelination: Structure and Function
Q28565839CaMKIIβ regulates oligodendrocyte maturation and CNS myelination
Q50507092Dystroglycan promotes filopodial formation and process branching in differentiating oligodendroglia.
Q38789322Extracellular cues influencing oligodendrocyte differentiation and (re)myelination
Q47814848GD1a Overcomes Inhibition of Myelination by Fibronectin via Activation of Protein Kinase A: Implications for Multiple Sclerosis
Q37915435Glia unglued: how signals from the extracellular matrix regulate the development of myelinating glia
Q28727258Identification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approach
Q37475066In Vitro Evaluation of Biocompatibility of Uncoated Thermally Reduced Graphene and Carbon Nanotube-Loaded PVDF Membranes with Adult Neural Stem Cell-Derived Neurons and Glia
Q37884392Integrin signaling in oligodendrocytes and its importance in CNS myelination
Q92288556Laminin α2, α4, and α5 Chains Positively Regulate Migration and Survival of Oligodendrocyte Precursor Cells
Q28568115P2Y12 receptor expression is a critical determinant of functional responsiveness to ATX's MORFO domain
Q38096247Signaling mechanisms regulating myelination in the central nervous system.
Q28505398Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS
Q30360840The Autotaxin-Lysophosphatidic Acid Axis Modulates Histone Acetylation and Gene Expression during Oligodendrocyte Differentiation
Q38255120The diverse roles and multiple forms of focal adhesion kinase in brain.
Q91161084The oligodendrocyte growth cone and its actin cytoskeleton: A fundamental element for progenitor cell migration and CNS myelination
Q47317704The protein tyrosine phosphatase Shp2 regulates oligodendrocyte differentiation and early myelination and contributes to timely remyelination.
Q36697506mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development

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