Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections.

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Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1002519
P932PMC publication ID3276557
P698PubMed publication ID22346752
P5875ResearchGate publication ID221844154

P50authorMichelle A OzbunQ59453176
P2093author name stringZurab Surviladze
Agnieszka Dziduszko
P2860cites workThe nature of large noncovalent complexes containing glycosyl-phosphatidylinositol-anchored membrane glycoproteins and protein tyrosine kinasesQ41601365
Signal transduction through MAP kinase cascadesQ41750250
The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cellsQ41867971
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Common and distinct elements in cellular signaling via EGF and FGF receptorsQ45165242
Herpes simplex virus targeting to the EGF receptor by a gD-specific soluble bridging moleculeQ45496884
Assembled baculovirus-expressed human papillomavirus type 11 L1 capsid protein virus-like particles are recognized by neutralizing monoclonal antibodies and induce high titres of neutralizing antibodiesQ45789709
Syndecan-1 Shedding Is Enhanced by LasA, a Secreted Virulence Factor ofPseudomonas aeruginosaQ60148130
31 Quantification of matrix metalloproteinases in tissue samplesQ72059246
A sensitive method to monitor ectodomain shedding of ligands of the epidermal growth factor receptorQ79740236
Surface-exposed amino acid residues of HPV16 L1 protein mediating interaction with cell surface heparan sulfateQ80641249
Carrageenan is a potent inhibitor of papillomavirus infectionQ21089628
Two highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytesQ21143868
HIV enters cells via endocytosis and dynamin-dependent fusion with endosomesQ22252313
The soluble serum protein Gas6 bridges virion envelope phosphatidylserine to the TAM receptor tyrosine kinase Axl to mediate viral entryQ24299966
Human papillomavirus infection requires cell surface heparan sulfateQ24529079
Atomic model of the papillomavirus capsidQ24534499
Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infectionQ24537437
A membrane-destabilizing peptide in capsid protein L2 is required for egress of papillomavirus genomes from endosomesQ24537580
Current understanding of the mechanism of HPV infectionQ24616134
Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healingQ24677883
Identification of the alpha6 integrin as a candidate receptor for papillomavirusesQ24678291
Adenovirus Binding to Blood Factors Results in Liver Cell Infection and HepatotoxicityQ27469833
Structural Basis of Oligosaccharide Receptor Recognition by Human PapillomavirusQ27666101
The emerging roles of serine protease cascades in the epidermisQ28257226
Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2Q28273441
Function of the syndecans--a family of cell surface proteoglycansQ28298962
Animal cell mutants defective in glycosaminoglycan biosynthesisQ28305815
Establishment of human papillomavirus infection requires cell cycle progressionQ28474811
Four year efficacy of prophylactic human papillomavirus quadrivalent vaccine against low grade cervical, vulvar, and vaginal intraepithelial neoplasia and anogenital warts: randomised controlled trialQ28750269
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell lineQ29547520
Papillomaviruses and cancer: from basic studies to clinical applicationQ29614745
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsQ29615216
Human papillomavirus is a necessary cause of invasive cervical cancer worldwideQ29617514
Functions of cell surface heparan sulfate proteoglycansQ29618521
Matrix metalloproteinases and the regulation of tissue remodellingQ29618747
Virus entry by endocytosisQ29619724
Vaccinia virus strains use distinct forms of macropinocytosis for host-cell entryQ30435768
Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infectionQ31036531
Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migrationQ33188043
Clathrin- and caveolin-independent entry of human papillomavirus type 16--involvement of tetraspanin-enriched microdomains (TEMs)Q33374009
Activation of EGFR on monocytes is required for human cytomegalovirus entry and mediates cellular motilityQ33563932
Rapid dissociation of HIV-1 from cultured cells severely limits infectivity assays, causes the inactivation ascribed to entry inhibitors, and masks the inherently high level of infectivity of virionsQ33676520
The role of furin in papillomavirus infectionQ33693739
Maturation of papillomavirus capsidsQ33834872
Human papillomavirus type 6b virus-like particles are able to activate the Ras-MAP kinase pathway and induce cell proliferationQ33839349
Human papillomavirus type 16 minor capsid protein l2 N-terminal region containing a common neutralization epitope binds to the cell surface and enters the cytoplasmQ33850734
The L1 major capsid protein of human papillomavirus type 11 recombinant virus-like particles interacts with heparin and cell-surface glycosaminoglycans on human keratinocytesQ33852592
Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activationQ33859710
Usage of heparan sulfate, integrins, and FAK in HPV16 infectionQ33905761
The EGF receptor - an essential regulator of multiple epidermal functionsQ33923625
Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenanQ34004909
A new type of membrane raft-like microdomains and their possible involvement in TCR signaling.Q34102524
In Vivo Mechanisms of Vaccine-Induced Protection against HPV InfectionQ34125906
Analysis of the infectious entry pathway of human papillomavirus type 33 pseudovirions.Q34146670
Papillomaviruses infect cells via a clathrin-dependent pathwayQ34187267
Different heparan sulfate proteoglycans serve as cellular receptors for human papillomavirusesQ34227402
Cell surface heparan sulfate and its roles in assisting viral infectionsQ34464575
Epidermal growth factor receptor is a cellular receptor for human cytomegalovirusQ34535736
Cell surface-binding motifs of L2 that facilitate papillomavirus infectionQ34743921
Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17.Q34781580
Animal models of papillomavirus pathogenesisQ35006173
Keratinocyte-secreted laminin 5 can function as a transient receptor for human papillomaviruses by binding virions and transferring them to adjacent cellsQ35024219
Virus activated filopodia promote human papillomavirus type 31 uptake from the extracellular matrixQ35659629
Binding and internalization of human papillomavirus type 33 virus-like particles by eukaryotic cellsQ35839345
Human papillomavirus type 31 uses a caveolin 1- and dynamin 2-mediated entry pathway for infection of human keratinocytesQ36098845
Inhibition of transfer to secondary receptors by heparan sulfate-binding drug or antibody induces noninfectious uptake of human papillomavirusQ36099326
MMPs and ADAMTSs: functional studiesQ36251025
Shedding of syndecan-1 and -4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinaseQ36316404
Insights into the role of heparan sulphate in fibroblast growth factor signallingQ36482135
Mechanisms of human papillomavirus type 16 neutralization by l2 cross-neutralizing and l1 type-specific antibodiesQ36540127
Interactions between heparan sulfate and proteins: the concept of specificityQ36552851
The role of syndecans in disease and wound healingQ36578144
Arrangement of L2 within the papillomavirus capsidQ36673336
Two AP1 sites binding JunB are essential for human papillomavirus type 18 transcription in keratinocytesQ36698234
Tumour microenvironment: laminin 332 in squamous-cell carcinomaQ36800958
Caveolin-1-dependent infectious entry of human papillomavirus type 31 in human keratinocytes proceeds to the endosomal pathway for pH-dependent uncoatingQ36898793
Keratinocyte growth factor receptorsQ36954792
Heparan sulfate-independent cell binding and infection with furin-precleaved papillomavirus capsidsQ36994627
Role of heparan sulfate in attachment to and infection of the murine female genital tract by human papillomavirusQ37099713
The biological properties of cetuximabQ37233886
Growth factors and cytokines in wound healingQ37364066
Heparanase: busy at the cell surfaceQ37371146
Signal co-operation between integrins and other receptor systemsQ37396456
Uterine cervical carcinoma: role of matrix metalloproteinases (review).Q37415383
The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface bindingQ37453403
Autocrine extracellular signal-regulated kinase (ERK) activation in normal human keratinocytes: metalloproteinase-mediated release of amphiregulin triggers signaling from ErbB1 to ERK.Q37497430
The signaling mechanisms of syndecan heparan sulfate proteoglycansQ37522781
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapyQ37609988
Shedding; towards a new paradigm of syndecan function in cancerQ37761400
Proteoglycans in health and disease: the multiple roles of syndecan sheddingQ37788814
Syndecans as cell surface receptors: Unique structure equates with functional diversityQ37808303
Papillomavirus particles assembled in 293TT cells are infectious in vivoQ39304696
Mechanism of HSV infection through soluble adapter-mediated virus bridging to the EGF receptor.Q39580061
Human papillomavirus type 31b infection of human keratinocytes and the onset of early transcription.Q39685873
An in vitro analysis of mechanical wounding-induced ligand-independent KGFR activationQ39901167
KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin.Q39976467
Papillomavirus virus-like particles activate the PI3-kinase pathway via alpha-6 beta-4 integrin upon binding.Q40266285
Generation of HPV pseudovirions using transfection and their use in neutralization assays.Q40340652
Further evidence that papillomavirus capsids exist in two distinct conformationsQ40344553
Tumor-targeted, systemic delivery of therapeutic viral vectors using hitchhiking on antigen-specific T cellsQ40371833
Human papillomavirus type 31b infection of human keratinocytes does not require heparan sulfateQ40423280
Shuttle of lentiviral vectors via transplanted cells in vivo.Q40512306
Kinetics of in vitro adsorption and entry of papillomavirus virionsQ40589262
Infectious human papillomavirus type 31b: purification and infection of an immortalized human keratinocyte cell lineQ40695908
The human papillomavirus type 16 E5-protein modulates ligand-dependent activation of the EGF receptor family in the human epithelial cell line HaCaT.Q41032558
Expression of AP1 during cellular differentiation determines human papillomavirus E6/E7 expression in stratified epithelial cellsQ41131505
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P921main subjectvirionQ1757347
P304page(s)e1002519
P577publication date2012-02-09
P1433published inPLOS PathogensQ283209
P1476titleEssential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections
P478volume8

Reverse relations

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