Opposing effects of bacitracin on human papillomavirus type 16 infection: enhancement of binding and entry and inhibition of endosomal penetration

scientific article published on 15 February 2012

Opposing effects of bacitracin on human papillomavirus type 16 infection: enhancement of binding and entry and inhibition of endosomal penetration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.05493-11
P932PMC publication ID3318660
P698PubMed publication ID22345461

P50authorMatthew P. BronnimannQ123571690
Janice A ChapmanQ123571698
Samuel K CamposQ56991195
Michelle A OzbunQ59453176
P2093author name stringMartin J Deymier
P2860cites workTwo highly conserved cysteine residues in HPV16 L2 form an intramolecular disulfide bond and are critical for infectivity in human keratinocytesQ21143868
Atomic model of the papillomavirus capsidQ24534499
The human protein disulphide isomerase family: substrate interactions and functional propertiesQ24537186
Cleavage of the papillomavirus minor capsid protein, L2, at a furin consensus site is necessary for infectionQ24537437
A membrane-destabilizing peptide in capsid protein L2 is required for egress of papillomavirus genomes from endosomesQ24537580
Bacitracin: substantiation and elimination of contaminating proteolytic activity and use as an affinity chromatography ligand to purify a siderophore-degrading enzymeQ77301710
Effect of divalent cations on the porcine kidney cortex membrane-bound form of dipeptidyl peptidase IVQ82535337
Identification of the dynein light chains required for human papillomavirus infectionQ82935198
Potentiation of the reductase activity of protein disulphide isomerase (PDI) by 19-nortestosterone, bacitracin, fluoxetine, and ammonium sulphateQ83245618
A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteinsQ24541564
Establishment of papillomavirus infection is enhanced by promyelocytic leukemia protein (PML) expressionQ24564089
Current understanding of the mechanism of HPV infectionQ24616134
Tissue-spanning redox gradient-dependent assembly of native human papillomavirus type 16 virionsQ24646183
Murine polyomavirus requires the endoplasmic reticulum protein Derlin-2 to initiate infectionQ24674111
Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interactionQ28369689
Target cell cyclophilins facilitate human papillomavirus type 16 infectionQ28475787
Differential cooperative enzymatic activities of protein disulfide isomerase family in protein foldingQ28570569
Presenilin/gamma-secretase cleaves CD46 in response to Neisseria infectionQ28817811
A guided tour into subcellular colocalization analysis in light microscopyQ29547199
Human papillomavirus is a necessary cause of invasive cervical cancer worldwideQ29617514
Role of endosomes in simian virus 40 entry and infectionQ30501717
Integrin activation and structural rearrangementQ30848202
A high-throughput turbidometric assay for screening inhibitors of protein disulfide isomerase activityQ31119993
Mutational analysis of human papillomavirus type 16 major capsid protein L1: the cysteines affecting the intermolecular bonding and structure of L1-capsidsQ31139631
Clathrin- and caveolin-independent entry of human papillomavirus type 16--involvement of tetraspanin-enriched microdomains (TEMs)Q33374009
Attachment and entry of Chlamydia have distinct requirements for host protein disulfide isomeraseQ33426342
The role of furin in papillomavirus infectionQ33693739
Intercapsomeric disulfide bonds in papillomavirus assembly and disassembly.Q33782413
Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteinesQ33785870
Maturation of papillomavirus capsidsQ33834872
Production of infectious human papillomavirus independently of viral replication and epithelial cell differentiationQ33879132
A presenilin-1 mutation identified in familial Alzheimer disease with cotton wool plaques causes a nearly complete loss of gamma-secretase activityQ33991052
Genital transmission of HPV in a mouse model is potentiated by nonoxynol-9 and inhibited by carrageenanQ34004909
Bacitracin is not a specific inhibitor of protein disulfide isomeraseQ34115847
Analysis of the infectious entry pathway of human papillomavirus type 33 pseudovirions.Q34146670
Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections.Q34162277
Papillomavirus infection requires gamma secretaseQ34178325
Papillomaviruses infect cells via a clathrin-dependent pathwayQ34187267
Inhibition of gamma secretase blocks HPV infectionQ34188410
Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiationQ34236875
ERp29 triggers a conformational change in polyomavirus to stimulate membrane bindingQ34462488
Mechanism of action of bacitracin: complexation with metal ion and C 55 -isoprenyl pyrophosphateQ34698463
Metal binding and structure-activity relationship of the metalloantibiotic peptide bacitracinQ34744785
Proteins of the PDI family: unpredicted non-ER locations and functionsQ34972858
Downregulation of protein disulfide isomerase inhibits infection by the mouse polyomavirusQ35139173
Virus activated filopodia promote human papillomavirus type 31 uptake from the extracellular matrixQ35659629
From road rash to top allergen in a flash: bacitracinQ35728904
Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substratesQ35756661
Neutralization of human papillomavirus with monoclonal antibodies reveals different mechanisms of inhibitionQ35947703
Human papillomavirus type 31 uses a caveolin 1- and dynamin 2-mediated entry pathway for infection of human keratinocytesQ36098845
Inhibition of transfer to secondary receptors by heparan sulfate-binding drug or antibody induces noninfectious uptake of human papillomavirusQ36099326
Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomeraseQ36281651
Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1.Q36285957
A protective and broadly cross-neutralizing epitope of human papillomavirus L2.Q36315086
A chemical method for fast and sensitive detection of DNA synthesis in vivoQ36497275
Mechanisms of human papillomavirus type 16 neutralization by l2 cross-neutralizing and l1 type-specific antibodiesQ36540127
Identification of a human papillomavirus type 16-specific epitope on the C-terminal arm of the major capsid protein L1Q36541188
Arrangement of L2 within the papillomavirus capsidQ36673336
Caveolin-1-dependent infectious entry of human papillomavirus type 31 in human keratinocytes proceeds to the endosomal pathway for pH-dependent uncoatingQ36898793
Role of heparan sulfate in attachment to and infection of the murine female genital tract by human papillomavirusQ37099713
Structure, attachment and entry of polyoma- and papillomavirusesQ37373696
Role of L2 cysteines in papillomavirus infection and neutralizationQ37410946
The initial steps leading to papillomavirus infection occur on the basement membrane prior to cell surface bindingQ37453403
Viral entry mechanisms: human papillomavirus and a long journey from extracellular matrix to the nucleusQ37480444
Come in and take your coat off - how host cells provide endocytosis for virus entryQ37777194
Regulation of matrix metalloproteinase activity in health and diseaseQ37810644
Thiol isomerases negatively regulate the cellular shedding activity of ADAM17.Q39722344
Functions of ERp57 in the folding and assembly of major histocompatibility complex class I moleculesQ40299278
Multi-chaperone complexes regulate the folding of interferon-gamma in the endoplasmic reticulum.Q40482547
Nuclear translocation of papillomavirus minor capsid protein L2 requires Hsc70.Q40556496
Surface conformational and linear epitopes on HPV-16 and HPV-18 L1 virus-like particles as defined by monoclonal antibodiesQ41172103
Identification of a dynein interacting domain in the papillomavirus minor capsid protein l2.Q41496726
Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cellsQ41623826
A PDI family network acts distinctly and coordinately with ERp29 to facilitate polyomavirus infectionQ42707006
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signalingQ44136286
An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell culturesQ44564031
Heparan sulfate proteoglycans interact exclusively with conformationally intact HPV L1 assemblies: basis for a virus-like particle ELISA.Q45551271
Analysis of type-restricted and cross-reactive epitopes on virus-like particles of human papillomavirus type 33 and in infected tissues using monoclonal antibodies to the major capsid proteinQ45781792
Redox Control of Exofacial Protein Thiols/Disulfides by Protein Disulfide IsomeraseQ61718588
Antagonists of bacitracinQ72274089
Enzyme destruction by a protease contaminant in bacitracinQ73983865
P4510describes a project that usesImageJQ1659584
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)4169-4181
P577publication date2012-02-15
P1433published inJournal of VirologyQ1251128
P1476titleOpposing effects of bacitracin on human papillomavirus type 16 infection: enhancement of binding and entry and inhibition of endosomal penetration
P478volume86

Reverse relations

cites work (P2860)
Q28087358A bacterial toxin and a nonenveloped virus hijack ER-to-cytosol membrane translocation pathways to cause disease
Q39253672A transmembrane domain and GxxxG motifs within L2 are essential for papillomavirus infection
Q59354292Cell-Penetrating Peptide Mediates Intracellular Membrane Passage of Human Papillomavirus L2 Protein to Trigger Retrograde Trafficking
Q38233232Coat as a dagger: the use of capsid proteins to perforate membranes during non-enveloped DNA viruses trafficking.
Q27677276Crystal structure of glycoprotein E2 from bovine viral diarrhea virus
Q36246390Cyclophilins facilitate dissociation of the human papillomavirus type 16 capsid protein L1 from the L2/DNA complex following virus entry
Q38366470DNA virus uncoating.
Q64887908Diverse Papillomavirus Types Induce Endosomal Tubulation.
Q37073350Furin Cleavage of L2 during Papillomavirus Infection: Minimal Dependence on Cyclophilins
Q36819964Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus.
Q39320596HPV entry into cells
Q38042837Host-cell factors involved in papillomavirus entry
Q27468807How Polyomaviruses Exploit the ERAD Machinery to Cause Infection
Q24307707Human papillomavirus infection is inhibited by host autophagy in primary human keratinocytes
Q36759798Identification of a role for the trans-Golgi network in human papillomavirus 16 pseudovirus infection
Q37712999Inhibition by cellular vacuolar ATPase impairs human papillomavirus uncoating and infection
Q36376623Interaction of human papillomavirus type 16 particles with heparan sulfate and syndecan-1 molecules in the keratinocyte extracellular matrix plays an active role in infection
Q35758680Kallikrein-8 Proteolytically Processes Human Papillomaviruses in the Extracellular Space To Facilitate Entry into Host Cells
Q59359263Molecular chaperones: from proteostasis to pathogenesis
Q37252724Multiple heparan sulfate binding site engagements are required for the infectious entry of human papillomavirus type 16.
Q37610842Opportunistic intruders: how viruses orchestrate ER functions to infect cells.
Q26801497Papillomavirus Infectious Pathways: A Comparison of Systems
Q38045782Principles of polyoma- and papillomavirus uncoating
Q38911523Protein disulfide isomerase mediates dengue virus entry in association with lipid rafts.
Q37198519The papillomavirus major capsid protein L1.
Q33626389Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis
Q34229884Vesicular trafficking of incoming human papillomavirus 16 to the Golgi apparatus and endoplasmic reticulum requires γ-secretase activity

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