| scholarly article | Q13442814 |
| P50 | author | Karen L Mohlke | Q59812940 |
| P2093 | author name string | Marie P Fogarty | |
| Swarooparani Vadlamudi | |||
| Maren E Cannon | |||
| Kyle J Gaulton | |||
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| Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. | Q34657904 | ||
| RNAi screening in primary human hepatocytes of genes implicated in genome-wide association studies for roles in type 2 diabetes identifies roles for CAMK1D and CDKAL1, among others, in hepatic glucose regulation | Q34804320 | ||
| Insights into the molecular mechanism for type 2 diabetes susceptibility at the KCNQ1 locus from temporal changes in imprinting status in human islets. | Q36635375 | ||
| Allele-specific transcriptional activity at type 2 diabetes-associated single nucleotide polymorphisms in regions of pancreatic islet open chromatin at the JAZF1 locus | Q36795945 | ||
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| Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion | Q40871524 | ||
| Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms | Q41729392 | ||
| The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver | Q42096203 | ||
| Using zebrafish transgenesis to test human genomic sequences for specific enhancer activity | Q42436462 | ||
| Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis | Q24609915 | ||
| Five years of GWAS discovery | Q24610574 | ||
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| Histone H3K27ac separates active from poised enhancers and predicts developmental state | Q24628758 | ||
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| Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2). | Q27937302 | ||
| Histone modifications at human enhancers reflect global cell-type-specific gene expression | Q28238467 | ||
| Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants | Q28249275 | ||
| The Human Epigenome Browser at Washington University | Q28254288 | ||
| Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes | Q28272915 | ||
| A statistical framework for joint eQTL analysis in multiple tissues | Q28397927 | ||
| The Genotype-Tissue Expression (GTEx) project | Q28657968 | ||
| Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci | Q29417126 | ||
| Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes | Q29417138 | ||
| Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4 | Q29618736 | ||
| Bridging the gap between genetic associations and molecular mechanisms for type 2 diabetes. | Q30354544 | ||
| Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. | Q30427183 | ||
| Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity | Q33646698 | ||
| A map of open chromatin in human pancreatic islets | Q33687905 | ||
| Identification of new genetic risk variants for type 2 diabetes | Q33700532 | ||
| Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits | Q33954469 | ||
| Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity | Q34027627 | ||
| Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk. | Q34061825 | ||
| Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell | Q34132210 | ||
| Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants | Q34377776 | ||
| Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants | Q34397259 | ||
| Global epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci | Q34518460 | ||
| The initiation of liver development is dependent on Foxa transcription factors | Q34650705 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 9 | |
| P921 | main subject | genome-wide association study | Q1098876 |
| type 2 diabetes | Q3025883 | ||
| P304 | page(s) | e1004633 | |
| P577 | publication date | 2014-09-11 | |
| P1433 | published in | PLOS Genetics | Q1893441 |
| P1476 | title | Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus | |
| P478 | volume | 10 |
| Q52690787 | A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression. |
| Q41974431 | A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a |
| Q38773037 | A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders |
| Q50015658 | A comprehensive review of the genetic and biological evidence supports a role for MicroRNA-137 in the etiology of schizophrenia. |
| Q38448065 | Computational analyses of type 2 diabetes-associated loci identified by genome-wide association studies |
| Q52691439 | DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1. |
| Q92983671 | Early-onset type 2 diabetes is associated with genetic variants of β-cell function in the Chinese Han population |
| Q57295524 | Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps |
| Q50025790 | Functional Variants Identified Efficiently through an Integrated Transcriptome and Epigenome Analysis |
| Q34501150 | Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci |
| Q100395003 | Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D |
| Q30277682 | Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans |
| Q57417302 | Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes |
| Q36084287 | Genomic approaches for understanding the genetics of complex disease |
| Q39155009 | Genomics of Islet (Dys)function and Type 2 Diabetes |
| Q93117380 | Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes |
| Q52690721 | Identification and functional analysis of glycemic trait loci in the China Health and Nutrition Survey. |
| Q96136701 | Identification of type 2 diabetes loci in 433,540 East Asian individuals |
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| Q48089880 | Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci. |
| Q28085471 | KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus |
| Q34044279 | Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort |
| Q38652238 | Mechanisms of Type 2 Diabetes Risk Loci |
| Q26795455 | New insights from monogenic diabetes for "common" type 2 diabetes |
| Q64064136 | Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk |
| Q94600515 | Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure |
| Q38652496 | Prioritising Causal Genes at Type 2 Diabetes Risk Loci |
| Q64972963 | TDG Gene Polymorphisms and Their Possible Association with Colorectal Cancer: A Case Control Study. |
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| Q31029687 | Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors |
| Q36121381 | Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function |
| Q30390388 | Type 2 diabetes: genetic data sharing to advance complex disease research |
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