The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling

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The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1023978105
P356DOI10.1007/S11011-012-9283-0
P932PMC publication ID4739736
P698PubMed publication ID22354752
P5875ResearchGate publication ID221851576

P2093author name stringStanley A Benkovic
Aaron A Hall
Alison E Willing
Hilary A Seifert
Keith R Pennypacker
Lisa A Collier
Christopher C Leonardo
Derrick D Rowe
P2860cites workReversible middle cerebral artery occlusion without craniectomy in ratsQ28268048
Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissueQ29615225
Cellular responses to interferon-gammaQ29618567
The spleen contributes to stroke-induced neurodegenerationQ33326528
Human umbilical cord blood cell therapy blocks the morphological change and recruitment of CD11b-expressing, isolectin-binding proinflammatory cells after middle cerebral artery occlusionQ33695510
Role of IL-1alpha and IL-1beta in ischemic brain damage.Q34084693
Cord blood administration induces oligodendrocyte survival through alterations in gene expressionQ34361392
Temporary focal ischemia in the mouse: technical aspects and patterns of Fluoro-Jade evident neurodegeneration.Q34410559
Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degenerationQ34421291
CD4+FoxP3+ regulatory T-cells in cerebral ischemic strokeQ34762334
Autoimmune responses to the brain after stroke are associated with worse outcomeQ35243961
The role of inflammation in CNS injury and diseaseQ36364424
T- and B-cell-deficient mice with experimental stroke have reduced lesion size and inflammationQ36992998
Human umbilical cord blood cells directly suppress ischemic oligodendrocyte cell deathQ37118662
Delayed treatments for stroke influence neuronal death in rat organotypic slice cultures subjected to oxygen glucose deprivationQ37387630
Sensitization to brain antigens after stroke is augmented by lipopolysaccharide.Q40384276
The hypothalamic-pituitary-adrenal axis and immune-mediated inflammationQ40506162
Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity.Q43715908
Splenectomy attenuates intestinal ischemia-reperfusion-induced acute lung injuryQ44630929
MEK-ERK signaling is involved in interferon-gamma-induced death of oligodendroglial progenitor cellsQ46736419
Sigma receptor activation reduces infarct size at 24 hours after permanent middle cerebral artery occlusion in ratsQ47336412
The spectrum of systemic immune alterations after murine focal ischemia: immunodepression versus immunomodulation.Q47796044
Impaired function of innate T lymphocytes and NK cells in the acute phase of ischemic strokeQ48459492
Timing of cord blood treatment after experimental stroke determines therapeutic efficacyQ48526513
Role of T lymphocytes and interferon-gamma in ischemic strokeQ48569519
Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke.Q48788015
Optimization of oligodendrocyte progenitor cell culture method for enhanced survivalQ48837649
IL-17 and IFN-gamma mRNA expression is increased in the brain and systemically after permanent middle cerebral artery occlusion in the rat.Q48910020
Immediate splenectomy decreases mortality and improves cognitive function of rats after severe traumatic brain injury.Q51023071
A Role for Interferon-Gamma in Focal Cerebral Ischemia in MiceQ58331894
Splenectomy ameliorates acute multiple organ damage induced by liver warm ischemia reperfusion in ratsQ63859559
Increased production of gelatinase B (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in cultureQ70956379
Splenectomy-reduced hepatic injury induced by ischemia/reperfusion in the ratQ71690337
Multiple extracellular signals are required for long-term oligodendrocyte survivalQ72930271
Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic strokeQ80399919
Experimental stroke induces massive, rapid activation of the peripheral immune systemQ81112631
Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after strokeQ83483859
P4510describes a project that usesImageJQ1659584
P433issue2
P921main subjectneurodegenerationQ1755122
P304page(s)131-141
P577publication date2012-02-22
P1433published inMetabolic Brain DiseaseQ15764352
P1476titleThe spleen contributes to stroke induced neurodegeneration through interferon gamma signaling
P478volume27