MEK-ERK signaling is involved in interferon-gamma-induced death of oligodendroglial progenitor cells

scientific article

MEK-ERK signaling is involved in interferon-gamma-induced death of oligodendroglial progenitor cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M603179200
P698PubMed publication ID16728393
P5875ResearchGate publication ID7055160

P2093author name stringDavid Pleasure
Takayuki Itoh
Aki Itoh
Makoto Horiuchi
P2860cites workThe role of p27Kip1 in gamma interferon-mediated growth arrest of mammary epithelial cells and related defects in mammary carcinoma cellsQ73359252
Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytesQ74244362
CDK inhibitors: positive and negative regulators of G1-phase progressionQ27860983
Mammalian MAP kinase signalling cascadesQ28204140
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 geneQ28507982
Bcl-2-related protein family gene expression during oligodendroglial differentiationQ28580229
IL-23 drives a pathogenic T cell population that induces autoimmune inflammationQ29547525
Stats: transcriptional control and biological impactQ29547776
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinasesQ29614338
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitisQ29620481
Histone H1 phosphorylation by Cdk2 selectively modulates mouse mammary tumor virus transcription through chromatin remodelingQ33969180
Mixed-lineage kinase control of JNK and p38 MAPK pathwaysQ34810173
Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitisQ35788671
Emerging concepts in periventricular white matter injuryQ36031255
The ERK cascade: a prototype of MAPK signalingQ36260506
Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblastsQ37256512
Primary demyelination in transgenic mice expressing interferon-gammaQ37660490
Cytokine-induced cell death in human oligodendroglial cell lines. II: Alterations in gene expression induced by interferon-gamma and tumor necrosis factor-alphaQ40552611
Histone H1(S)-3 phosphorylation in Ha-ras oncogene-transformed mouse fibroblastsQ40685497
Decreased growth inhibitory responses of squamous carcinoma cells to interferon-gamma involve failure to recruit cki proteins into cdk2 complexesQ40768296
Exacerbations of multiple sclerosis in patients treated with gamma interferonQ40797798
Cytokine induction of inducible nitric oxide synthase in an oligodendrocyte cell line: role of p38 mitogen-activated protein kinase activationQ40975847
Hydrogen peroxide activation of multiple mitogen-activated protein kinases in an oligodendrocyte cell line: role of extracellular signal-regulated kinase in hydrogen peroxide-induced cell deathQ40981560
IFNgamma inhibition of cell growth in glioblastomas correlates with increased levels of the cyclin dependent kinase inhibitor p21WAF1/CIP1.Q40982408
Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expressionQ41103827
Mechanisms of immune injury in multiple sclerosisQ41157659
Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1.Q41199732
Monoclonal anti-gamma interferon antibodies enhance experimental allergic encephalomyelitisQ41588487
Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivoQ42173194
Cyclin E-CDK2 is a regulator of p27Kip1.Q42800258
AMPA glutamate receptor-mediated calcium signaling is transiently enhanced during development of oligodendrocytes.Q44027716
Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicityQ44263018
IFN-gamma induces apoptosis in developing mast cellsQ44913107
Developmental differences in HO-induced oligodendrocyte cell death: role of glutathione, mitogen-activated protein kinases and caspase 3.Q44959839
Alternative activation of STAT1 and STAT3 in response to interferon-gammaQ45000443
Interferon-gamma inhibits cell cycle exit in differentiating oligodendrocyte progenitor cellsQ46514033
Cytokine-induced cell death in human oligodendroglial cell lines: I. Synergistic effects of IFN-gamma and TNF-alpha on apoptosisQ47436363
Multiple sclerosis: cytokine receptors on oligodendrocytes predict innate regulationQ48101693
Caspase-3 expression by cerebellar granule neurons is regulated by calcium and cyclic AMP.Q48149085
Synergistic stimulation of MHC class I and IRF-1 gene expression by IFN-gamma and TNF-alpha in oligodendrocytes.Q48383146
LPS/IFN-gamma cytotoxicity in oligodendroglial cells: role of nitric oxide and protection by the anti-inflammatory cytokine IL-10.Q49043684
Interferon-gamma confers resistance to experimental allergic encephalomyelitis.Q52520772
Interleukin-1 beta converting enzyme.Q55065365
Cell cycle arrest induced by ectopic expression of p27 is not sufficient to promote oligodendrocyte differentiationQ64381071
Reversible inhibitory effects of interferon-gamma and tumour necrosis factor-alpha on oligodendroglial lineage cell proliferation and differentiation in vitroQ71383297
Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar developmentQ71543637
Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated: up-regulation of p27(Kip1)Q73076685
P433issue29
P407language of work or nameEnglishQ1860
P921main subjectoligodendrocyteQ916698
P304page(s)20095-20106
P577publication date2006-05-25
P1433published inJournal of Biological ChemistryQ867727
P1476titleMEK-ERK signaling is involved in interferon-gamma-induced death of oligodendroglial progenitor cells
P478volume281

Reverse relations

cites work (P2860)
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