Ligand-directed targeting of genes to the site of disease

scientific article

Ligand-directed targeting of genes to the site of disease is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1008155992
P356DOI10.1038/NM0103-135
P698PubMed publication ID12514727

P2093author name stringThomas J Wickham
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Targeting avian leukosis virus subgroup A vectors by using a TVA-VEGF bridge proteinQ33837118
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"Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lungQ33841039
Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactionsQ33849565
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Pulmonary collectins and innate host defense of the lungQ34184446
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Retroviral vectors preloaded with a viral receptor-ligand bridge protein are targeted to specific cell typesQ36437996
Selective gene delivery toward gastric and esophageal adenocarcinoma cells via EpCAM-targeted adenoviral vectorsQ38298395
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Single-chain antibody displayed on a recombinant measles virus confers entry through the tumor-associated carcinoembryonic antigenQ39605575
Targeting adenoviral vectors by using the extracellular domain of the coxsackie-adenovirus receptor: improved potency via trimerizationQ39682554
Adenovirus binding to the coxsackievirus and adenovirus receptor or integrins is not required to elicit brain inflammation but is necessary to transduce specific neural cell typesQ39682986
Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.Q39882081
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Collectins and viral infectionQ40466999
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Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivoQ40782543
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Transferrin-liposome-mediated systemic p53 gene therapy in combination with radiation results in regression of human head and neck cancer xenograftsQ40910125
PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene deliveryQ40931003
Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab'gamma)2 antibodyQ40969562
Antiviral activity of bovine collectins against rotaviruses.Q41007198
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Retroviral display of functional binding domains fused to the amino terminus of influenza hemagglutinin.Q41482419
Genetic capsid modifications allow efficient re-targeting of adeno-associated virus type 2.Q42609041
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Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.Q43583253
Tumor regression by targeted gene delivery to the neovasculatureQ44044889
Cell-specific targeting of Sindbis virus vectors displaying IgG-binding domains of protein A.Q45761208
Selective transduction of protease-rich tumors by matrix-metalloproteinase-targeted retroviral vectorsQ45862326
Targeting an adenoviral gene vector to cytokine-activated vascular endothelium via E-selectinQ45862541
A blood-tumor barrier limits gene transfer to experimental liver cancer: the effect of vasoactive compounds.Q45872992
Systemic administration of a matrix-targeted retroviral vector is efficacious for cancer gene therapy in miceQ45874393
Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic applicationQ45877889
Targeting endothelium for gene therapy via receptors up-regulated during angiogenesis and inflammationQ45885138
Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicityQ45888026
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)135-139
P577publication date2003-01-01
P1433published inNature MedicineQ1633234
P1476titleLigand-directed targeting of genes to the site of disease
P478volume9

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