| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1045029496 |
| P356 | DOI | 10.1186/BCR2622 |
| P8608 | Fatcat ID | release_3fvzbsud4vh2jescmisg7iz64y |
| P932 | PMC publication ID | 2949652 |
| P698 | PubMed publication ID | 20687930 |
| P5875 | ResearchGate publication ID | 45507329 |
| P50 | author | Carol A Lange | Q101563783 |
| P2093 | author name string | Nancy E Castro | |
| P2860 | cites work | Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability | Q22254678 |
| Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6 | Q24300274 | ||
| BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest | Q24310412 | ||
| Identification of STAT3 as a specific substrate of breast tumor kinase | Q24311267 | ||
| Regulated association of protein kinase B/Akt with breast tumor kinase | Q24314300 | ||
| Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours | Q24314895 | ||
| Erk5 participates in neuregulin signal transduction and is constitutively active in breast cancer cells overexpressing ErbB2 | Q24538180 | ||
| Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK. | Q24540541 | ||
| A novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRK | Q28138242 | ||
| MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway | Q28139990 | ||
| Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation | Q28140199 | ||
| BRK/Sik expression in the gastrointestinal tract and in colon tumors | Q28140957 | ||
| MEKK2 associates with the adapter protein Lad/RIBP and regulates the MEK5-BMK1/ERK5 pathway | Q28143630 | ||
| MEK5 overexpression is associated with metastatic prostate cancer, and stimulates proliferation, MMP-9 expression and invasion | Q28180881 | ||
| Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells | Q28183216 | ||
| Role of the Brk SH3 domain in substrate recognition | Q28191632 | ||
| Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases | Q28202022 | ||
| Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor | Q28286729 | ||
| Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor | Q28298083 | ||
| Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine | Q28509681 | ||
| Interaction between Brk kinase and insulin receptor substrate-4. | Q30160247 | ||
| A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract | Q30193721 | ||
| Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells | Q33283847 | ||
| MET and MYC cooperate in mammary tumorigenesis | Q33926873 | ||
| Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation | Q34097397 | ||
| Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes. | Q35088231 | ||
| The c-met/HGF receptor in human tumours. | Q35608704 | ||
| Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells | Q36090650 | ||
| MAPK signalling: ERK5 versus ERK1/2. | Q36553050 | ||
| A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation | Q36821163 | ||
| Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival | Q37015135 | ||
| The RON receptor tyrosine kinase promotes MSP-independent cell spreading and survival in breast epithelial cells | Q37066428 | ||
| Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis | Q37399415 | ||
| Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development. | Q37467189 | ||
| Role of breast tumour kinase in the in vitro differentiation of HaCaT cells. | Q38441536 | ||
| Simultaneous over-expression of the Her2/neu and PTK6 tyrosine kinases in archival invasive ductal breast carcinomas | Q38444122 | ||
| MDA-MB-435 and M14 cell lines: identical but not M14 melanoma? | Q39834203 | ||
| Oncogenic functions of PTK6 are enhanced by its targeting to plasma membrane but abolished by its targeting to nucleus | Q39869787 | ||
| Inducing effects of hepatocyte growth factor on the expression of vascular endothelial growth factor in human colorectal carcinoma cells through MEK and PI3K signaling pathways. | Q40127506 | ||
| Forced expression of RDH10 gene retards growth of HepG2 cells. | Q40183970 | ||
| The BRK tyrosine kinase is expressed in high-grade serous carcinoma of the ovary | Q40253367 | ||
| Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration | Q40368400 | ||
| The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis | Q40388197 | ||
| The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2. | Q40506613 | ||
| The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells | Q41563732 | ||
| The tyrosine kinase receptor met and its ligand HGF are co-expressed and functionally active in HHV-8 positive primary effusion lymphoma. | Q42619075 | ||
| Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway | Q43691664 | ||
| Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation | Q44539661 | ||
| Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration | Q45345934 | ||
| Overexpression of PTK6 (breast tumor kinase) protein--a prognostic factor for long-term breast cancer survival--is not due to gene amplification. | Q45924298 | ||
| ERK activation propagates in epithelial cell sheets and regulates their migration during wound healing. | Q47765558 | ||
| Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma | Q73420821 | ||
| BRK tyrosine kinase expression in a high proportion of human breast carcinomas | Q73615071 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | breast cancer | Q128581 |
| cell migration | Q189092 | ||
| breast neoplasm | Q23929670 | ||
| P304 | page(s) | R60 | |
| P577 | publication date | 2010-08-05 | |
| P1433 | published in | Breast Cancer Research | Q2208481 |
| P1476 | title | Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells | |
| P478 | volume | 12 |
| Q36678367 | A comparison of epithelial-to-mesenchymal transition and re-epithelialization |
| Q36080701 | A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis |
| Q36693131 | Breast Tumor Kinase (Brk/PTK6) Is Induced by HIF, Glucocorticoid Receptor, and PELP1-Mediated Stress Signaling in Triple-Negative Breast Cancer |
| Q34912116 | Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression. |
| Q30009178 | Cancer-Associated Mutations in Breast Tumor Kinase/PTK6 Differentially Affect Enzyme Activity and Substrate Recognition |
| Q38080556 | Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer |
| Q34659926 | Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells |
| Q45318098 | ERBB2 Activates PTK6 Signaling |
| Q98771160 | ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer |
| Q37977186 | ERK5 and its role in tumour development |
| Q34212935 | Expression of the phosphorylated MEK5 protein is associated with TNM staging of colorectal cancer |
| Q34036107 | HIF-1α-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion |
| Q64065870 | Impact of ERK5 on the Hallmarks of Cancer |
| Q33917578 | Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer |
| Q35560430 | MAPK7 Regulates EMT Features and Modulates the Generation of CTCs |
| Q35683544 | Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK. |
| Q34085432 | Mechanisms of HGF/Met signaling to Brk and Sam68 in breast cancer progression |
| Q27318931 | Met receptor acts uniquely for survival and morphogenesis of EGFR-dependent normal mammary epithelial and cancer cells |
| Q24606871 | Met receptors induce Sam68-dependent cell migration by activation of alternate extracellular signal-regulated kinase family members |
| Q39514016 | Microenvironment induced spheroid to sheeting transition of immortalized human keratinocytes (HaCaT) cultured in microbubbles formed in polydimethylsiloxane |
| Q33645135 | Olive phenolics as c-Met inhibitors: (-)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models |
| Q50133871 | PD2/PAF1 at the Crossroads of the Cancer Network |
| Q39125642 | PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer |
| Q35834635 | PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim. |
| Q35161670 | PTK6 promotes cancer migration and invasion in pancreatic cancer cells dependent on ERK signaling |
| Q34781357 | Pathways driving the endocytosis of mutant and wild-type EGFR in cancer |
| Q36940726 | Protein tyrosine kinase 6 is associated with nasopharyngeal carcinoma poor prognosis and metastasis |
| Q39268132 | Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT. |
| Q28115210 | Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate |
| Q45318326 | Signaling by PTK6 |
| Q90630036 | Steroid Receptors as MAPK Signaling Sensors in Breast Cancer: Let the Fates Decide |
| Q42357549 | Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage |
| Q41905885 | Targeting the BMK1 MAP kinase pathway in cancer therapy. |
| Q89507021 | Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis |
| Q28821187 | The oleocanthal-based homovanillyl sinapate as a novel c-Met inhibitor |
| Q54231260 | miR-143 suppresses epithelial-mesenchymal transition and inhibits tumor growth of breast cancer through down-regulation of ERK5. |
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