scholarly article | Q13442814 |
P2093 | author name string | Francesco Beguinot | |
Alessandra Trencia | |||
Angela Cassese | |||
Anna Perfetti | |||
Claudia Miele | |||
Francesco Oriente | |||
Giovanni Vigliotta | |||
Pietro Formisano | |||
Stefania Santopietro | |||
Chiara Romano | |||
Giancarlo Troncone | |||
Cecilia Tiveron | |||
Giuseppe Portella | |||
Francesca Fiory | |||
Laura Tatangelo | |||
Maria Alessandra Maitan | |||
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PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus | Q24316231 | ||
Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action | Q24683017 | ||
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 | Q25938983 | ||
Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them | Q28142706 | ||
PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase | Q28204643 | ||
Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA-15 anti-apoptotic function | Q28215522 | ||
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells | Q28215810 | ||
Failure of insulin-regulated recruitment of the glucose transporter GLUT4 in cardiac muscle of obese Zucker rats is associated with alterations of small-molecular-mass GTP-binding proteins | Q28577351 | ||
The phosphoprotein protein PEA-15 inhibits Fas- but increases TNF-R1-mediated caspase-8 activity and apoptosis | Q28587650 | ||
Knockout of PKC alpha enhances insulin signaling through PI3K | Q28590618 | ||
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Global and societal implications of the diabetes epidemic | Q29614551 | ||
Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetes | Q33853693 | ||
Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase | Q33958737 | ||
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Diabetes mellitus and genetically programmed defects in beta-cell function | Q34462316 | ||
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Function and dysfunction of aPKC isoforms for glucose transport in insulin-sensitive and insulin-resistant states | Q34688703 | ||
IRS proteins and the common path to diabetes | Q34778267 | ||
Insulin action and the regulation of hexose transport | Q40284376 | ||
Protein kinase C (PKC)-alpha activation inhibits PKC-zeta and mediates the action of PED/PEA-15 on glucose transport in the L6 skeletal muscle cells | Q40803281 | ||
Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms | Q41729392 | ||
The IR1152 mutant insulin receptor selectively impairs insulin action in skeletal muscle but not in liver. | Q42491060 | ||
Photoaffinity labelling of cardiac membrane GTP-binding proteins in response to insulin | Q42505170 | ||
Rosiglitazone, insulin treatment, and fasting correct defective activation of protein kinase C-zeta/lambda by insulin in vastus lateralis muscles and adipocytes of diabetic rats | Q43543575 | ||
Quantitative measurement of sn-1,2-diacylglycerols | Q45205999 | ||
Tissue and isoform-selective activation of protein kinase C in insulin-resistant obese Zucker rats - effects of feeding. | Q51562050 | ||
Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance. | Q52540333 | ||
Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells. | Q54018179 | ||
1,2-Diacylglycerol and ceramide levels in rat skeletal muscle and liver in vivo. Studies with insulin, exercise, muscle denervation, and vasopressin. | Q54324021 | ||
Thiazolidinedione treatment enhances insulin effects on protein kinase C-zeta /lambda activation and glucose transport in adipocytes of nondiabetic and Goto-Kakizaki type II diabetic rats | Q73631016 | ||
METABOLISM OF ISOLATED FAT CELLS. I. EFFECTS OF HORMONES ON GLUCOSE METABOLISM AND LIPOLYSIS | Q76853134 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | preproinsulin | Q7240673 |
overexpression | Q61643320 | ||
P304 | page(s) | 5005-5015 | |
P577 | publication date | 2004-06-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action | |
P478 | volume | 24 |
Q42700870 | A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells. |
Q34667784 | Adenoviral gene transfer of PLD1-D4 enhances insulin sensitivity in mice by disrupting phospholipase D1 interaction with PED/PEA-15. |
Q34252924 | Age-related impairment in insulin release: the essential role of β(2)-adrenergic receptor |
Q43565613 | Biomechanical insult switches PEA-15 activity to uncouple its anti-apoptotic function and promote erk mediated tissue remodeling |
Q35001275 | Characterization of a MAPK scaffolding protein logic gate in gonadotropes. |
Q35837406 | Clozapine impairs insulin action by up-regulating Akt phosphorylation and Ped/Pea-15 protein abundance |
Q39541782 | Comparison between fibroblast wound healing and cell random migration assays in vitro |
Q48206002 | Expression of phosphoprotein enriched in astrocytes 15 kDa (PEA-15) in astrocytic tumors: a novel approach of correlating malignancy grade and prognosis |
Q43097133 | Hepatocyte nuclear factor (HNF)-4alpha-driven epigenetic silencing of the human PED gene. |
Q43154745 | Molecular cloning and characterization of the human PED/PEA-15 gene promoter reveal antagonistic regulation by hepatocyte nuclear factor 4alpha and chicken ovalbumin upstream promoter transcription factor II. |
Q42913727 | NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites |
Q28476047 | Negative regulators of insulin signaling revealed in a genome-wide functional screen |
Q26799216 | On the Quest of Cellular Functions of PEA-15 and the Therapeutic Opportunities |
Q43269412 | Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-beta activity and TGF-beta1 expression. |
Q42272320 | PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms |
Q36028460 | PED/PEA-15 induces autophagy and mediates TGF-beta1 effect on muscle cell differentiation |
Q34663501 | PED/PEA-15 inhibits hydrogen peroxide-induced apoptosis in Ins-1E pancreatic beta-cells via PLD-1 |
Q54408005 | PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice. |
Q42416060 | Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice |
Q36466778 | Peroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1 |
Q53337896 | Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation. |
Q34024181 | Phosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states |
Q35190978 | Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase C delta-dependent mechanism |
Q39652158 | Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase |
Q36898758 | Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism. |
Q40393314 | Raised expression of the antiapoptotic protein ped/pea-15 increases susceptibility to chemically induced skin tumor development. |
Q46549512 | Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells. |
Q39232367 | Targetting PED/PEA-15 for diabetes treatment. |
Q40093567 | The PEA-15/PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK/MAP kinase pathway. |
Q51488380 | The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes. |
Q37112520 | The roles of MAPKs in disease |
Q28564173 | Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling |
Q38405367 | Understanding type 2 diabetes: from genetics to epigenetics |
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