Reactive oxygen species suppress cardiac NaV1.5 expression through Foxo1.

scientific article

Reactive oxygen species suppress cardiac NaV1.5 expression through Foxo1. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...732738M
P356DOI10.1371/JOURNAL.PONE.0032738
P932PMC publication ID3293505
P698PubMed publication ID22400069
P5875ResearchGate publication ID221686457

P50authorHengjiang DongQ73409468
P2093author name stringXiang Li
Joseph A Hill
Tao You
Bo Ye
Haodong Xu
Faqian Li
Henry H Dong
Weike Mao
P2860cites workAFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1Q22254000
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Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologuesQ24532085
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)Q24551018
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Blocking late sodium current reduces hydrogen peroxide-induced arrhythmogenic activity and contractile dysfunction.Q53630608
Abnormal electrical activity induced by free radical generating systems in isolated cardiocytesQ68074350
Alterations of Na+ currents in myocytes from epicardial border zone of the infarcted heart. A possible ionic mechanism for reduced excitability and postrepolarization refractorinessQ73454279
Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequenceQ74299421
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2Q28216784
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasisQ28285131
Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variantsQ28504505
Perinatal loss of Nkx2-5 results in rapid conduction and contraction defectsQ28593447
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stressQ29619436
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interactionQ29619822
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transportQ33292269
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Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization.Q34094624
Silent information regulator 1 protects the heart from ischemia/reperfusionQ34412288
Direct measurement of free radical generation following reperfusion of ischemic myocardiumQ34602572
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Remodeling in cells from different regions of the reentrant circuit during ventricular tachycardiaQ34893485
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The "heartbreak" of older age.Q35679502
Four kinetically distinct depolarization-activated K+ currents in adult mouse ventricular myocytesQ36420431
Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activityQ37074144
FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammationQ37393706
FoxO transcription factors promote autophagy in cardiomyocytesQ37459990
A transcription-independent function of FOXO1 in inhibition of androgen-independent activation of the androgen receptor in prostate cancer cellsQ39905997
Forkhead transcription factors coordinate expression of myocardial KATP channel subunits and energy metabolismQ40023854
CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damageQ40220552
Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.Q40301333
Oxidative mediated lipid peroxidation recapitulates proarrhythmic effects on cardiac sodium channelsQ40352026
The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocationQ40352430
FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.Q40493379
Functional expression of L- and T-type Ca2+ channels in murine HL-1 cellsQ40597543
The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factorsQ42067514
Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.Q42218987
Hydrogen peroxide changes in ischemic and reperfused heart. Cytochemistry and biochemical and X-ray microanalysisQ42274524
Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequenceQ42477315
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signalingQ42500888
Oxidative-stress-induced afterdepolarizations and calmodulin kinase II signalingQ42561090
Reactive oxygen species promote angiogenesis in the infarcted rat heartQ43275808
Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.Q46297094
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectreactive oxygen speciesQ424361
P304page(s)e32738
P577publication date2012-02-29
P1433published inPLOS OneQ564954
P1476titleReactive oxygen species suppress cardiac NaV1.5 expression through Foxo1.
P478volume7

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cites work (P2860)
Q92662040A small-molecule LF3 abrogates β-catenin/TCF4-mediated suppression of NaV1.5 expression in HL-1 cardiomyocytes
Q42158072Activation of Wnt/β-catenin signaling by hydrogen peroxide transcriptionally inhibits NaV1.5 expression
Q34154347Deletion of FoxO1 leads to shortening of QRS by increasing Na(+) channel activity through enhanced expression of both cardiac NaV1.5 and β3 subunit
Q35188267Deletion of PDK1 causes cardiac sodium current reduction in mice
Q104607562Elevated EZH2 in ischemic heart disease epigenetically mediates suppression of NaV1.5 expression
Q30544004Elevated nuclear Foxo1 suppresses excitability of skeletal muscle fibers
Q28304358Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype
Q28292930Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias
Q38369684Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications.
Q38184989Regulation of voltage-gated sodium channel expression in cancer: hormones, growth factors and auto-regulation
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Q28573894TGF-β1, released by myofibroblasts, differentially regulates transcription and function of sodium and potassium channels in adult rat ventricular myocytes
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Q38585131The cardiac sodium channel gene SCN5A and its gene product NaV1.5: Role in physiology and pathophysiology.
Q34152309The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles.

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