Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants

scientific journal article

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00644.2001
P698PubMed publication ID11834499

P50authorChristian BollensdorffQ47147700
P2093author name stringKlaus Benndorf
Thomas Zimmer
Eckhard Birch-Hirschfeld
Volker Haufe
P2860cites workImproved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patchesQ22337395
Molecular cloning of an atypical voltage-gated sodium channel expressed in human heart and uterus: evidence for a distinct gene familyQ24336511
Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channelQ24563388
Primary structure of the adult human skeletal muscle voltage‐dependent sodium channelQ28210170
On/off regulation of gene expression at the level of splicingQ28281812
Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytesQ28580912
Inactivation of sodium channels in isolated myocardial mouse cells.Q30321569
Modulation of cardiac Na+ current phenotype by beta1-subunit expressionQ32031304
Alterations of sodium channel kinetics and gene expression in the postinfarction remodeled myocardiumQ32090022
Cellular and molecular biology of voltage-gated sodium channelsQ34238906
Molecular cloning of a putative tetrodotoxin-resistant rat heart Na+ channel isoformQ34314458
Alternative splicing of the sodium channel SCN8A predicts a truncated two-domain protein in fetal brain and non-neuronal cells.Q34439038
Expression of diverse Na+ channel messenger RNAs in rat myocardium. Evidence for a cardiac-specific Na+ channelQ34577727
Functional association of the beta 1 subunit with human cardiac (hH1) and rat skeletal muscle (mu 1) sodium channel alpha subunits expressed in Xenopus oocytesQ36435670
Structure and function of voltage-sensitive ion channelsQ38193558
Alternative splicing in the control of gene expressionQ38763422
Inactivation of single cardiac Na+ channels in three different gating modesQ40129475
Developmentally regulated alternative RNA splicing of rat brain sodium channel mRNAsQ40507940
Electrophysiological characteristics of cloned skeletal and cardiac muscle sodium channelsQ41180157
Splicing together the unfolded-protein responseQ41397066
Effect of tetrodotoxin on action potentials of the conducting system in the dog heartQ41533455
Properties of single cardiac Na channels at 35 degrees CQ41937368
Primary structure and functional expression of a mammalian skeletal muscle sodium channelQ42189395
Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.Q42604432
Characterization of the sodium current in single human atrial myocytesQ44230496
A persistent sodium current in rat ventricular myocytesQ46623765
Calcium channel splicing: mind your Ps and Qs.Q48213744
The cloned cardiac Na channel alpha-subunit expressed in Xenopus oocytes show gating and blocking properties of native channelsQ48428161
A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive propertiesQ48479782
Sodium current in single myocardial mouse cells.Q51828035
Sodium Currents in Segments of Human Heart CellsQ51854329
Sodium current in single rat heart muscle cells.Q51865832
Multiple levels of native cardiac Na+ channels at elevated temperature measured with high-bandwidth/low-noise patch clamp.Q54052489
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectSodium channel, voltage-gated, type IV, alphaQ14905713
Sodium channel, voltage-gated, type V, alphaQ14905733
P304page(s)H1007–1017
P577publication date2002-03-01
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleMouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants
P478volume282

Reverse relations

cites work (P2860)
Q48651379A slowly inactivating sodium current (INa2) in the plateau range in canine cardiac Purkinje single cells
Q33796526Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T.
Q33892566Alternative splicing of the cardiac sodium channel creates multiple variants of mutant T1620K channels
Q37936683Biology of cardiac sodium channel Nav1.5 expression
Q36989039Cardiac expression of skeletal muscle sodium channels increases longitudinal conduction velocity in the canine 1-week myocardial infarction.
Q38201409Cardiac potassium channel subtypes: new roles in repolarization and arrhythmia
Q38115058Cardiac sodium transport and excitation-contraction coupling
Q37670013Characterization of a novel BmαTX47 toxin modulating sodium channels: the crucial role of expression vectors in toxin pharmacological activity
Q37187840DIFFERENCES IN IONIC CURRENTS BETWEEN CANINE MYOCARDIAL AND PURKINJE CELLS.
Q34435132Distribution and functional characterization of human Nav1.3 splice variants
Q46601491Electrophysiological and molecular identification of voltage-gated sodium channels in murine vascular myocytes
Q42782031Electrophysiological properties of mouse and epitope-tagged human cardiac sodium channel Na v1.5 expressed in HEK293 cells.
Q42857299Expression of skeletal muscle Na(V)1.4 Na channel isoform in canine cardiac Purkinje myocytes.
Q28588673Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart
Q51938135Gene duplications and evolution of vertebrate voltage-gated sodium channels.
Q36787316Increased late sodium current contributes to long QT-related arrhythmia susceptibility in female mice
Q26829681Ion Channels in the Heart
Q33290470Molecular cloning and analysis of zebrafish voltage-gated sodium channel beta subunit genes: implications for the evolution of electrical signaling in vertebrates
Q47932254Molecular expression of multiple Nav1.5 splice variants in the frontal lobe of the human brain.
Q33828302Multiple Nav1.5 isoforms are functionally expressed in the brain and present distinct expression patterns compared with cardiac Nav1.5.
Q34536165Neuronal differentiation of human mesenchymal stem cells: changes in the expression of the Alzheimer's disease-related gene seladin-1.
Q37304434Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.
Q82029865Periodic paralysis
Q37101362Post-partum variation in the expression of paternal care is unrelated to urinary steroid metabolites in marmoset fathers
Q38694637Predicting QRS and PR interval prolongations in humans using nonclinical data.
Q45930155Pyramidal cells of rodent presubiculum express a tetrodotoxin-insensitive Na+ current.
Q34188064Reactive oxygen species suppress cardiac NaV1.5 expression through Foxo1.
Q37687456Repolarization of the cardiac action potential. Does an increase in repolarization capacity constitute a new anti-arrhythmic principle?
Q44978747Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking
Q24294528Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals
Q34469251Sodium current properties of primary skeletal myocytes and cardiomyocytes derived from different mouse strains.
Q28279905Structure and function of splice variants of the cardiac voltage-gated sodium channel Na(v)1.5
Q28214636Structure of the sodium channel gene SCN11A: evidence for intron-to-exon conversion model and implications for gene evolution
Q42152097The intracellular domain of the beta 2 subunit modulates the gating of cardiac Na v 1.5 channels
Q37303962The sodium channel Nav1.5a is the predominant isoform expressed in adult mouse dorsal root ganglia and exhibits distinct inactivation properties from the full-length Nav1.5 channel.
Q38972172Transmural gradients in ion channel and auxiliary subunit expression
Q35667228Voltage-gated Na+ channels: multiplicity of expression, plasticity, functional implications and pathophysiological aspects
Q38381248Voltage-gated sodium channels in the mammalian heart

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