| scholarly article | Q13442814 |
| P50 | author | Norbert Weissmann | Q51120582 |
| P2093 | author name string | Nermin Kuzkaya | |
| Sergey Dikalov | |||
| David G Harrison | |||
| P433 | issue | 25 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | endothelium | Q111140 |
| sapropterin | Q419808 | ||
| P304 | page(s) | 22546-22554 | |
| P577 | publication date | 2003-04-10 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase | |
| P478 | volume | 278 |
| Q37279303 | A novel hydrogen sulfide prodrug, SG1002, promotes hydrogen sulfide and nitric oxide bioavailability in heart failure patients |
| Q37682336 | A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance |
| Q43199664 | A weapon of endothelial cells for fighting vascular disease |
| Q55317359 | Acute Hyperbaric Oxygenation, Contrary to Intermittent Hyperbaric Oxygenation, Adversely Affects Vasorelaxation in Healthy Sprague-Dawley Rats due to Increased Oxidative Stress. |
| Q42412241 | Acute inhibition of guanosine triphosphate cyclohydrolase 1 uncouples endothelial nitric oxide synthase and elevates blood pressure |
| Q42207780 | Acute tetrahydrobiopterin supplementation attenuates sympathetic vasoconstrictor responsiveness in resting and contracting skeletal muscle of healthy rats |
| Q28394291 | Aging and the control of human skin blood flow |
| Q34627792 | Alternative splicing impairs soluble guanylyl cyclase function in aortic aneurysm |
| Q41584496 | An Acute Dose of Specific Grape and Apple Polyphenols Improves Endurance Performance: A Randomized, Crossover, Double-Blind versus Placebo Controlled Study. |
| Q38397635 | Antidiabetic agents and endothelial dysfunction - beyond glucose control |
| Q39252696 | Antioxidant therapy for management of oxidative stress induced hypertension |
| Q35457871 | Antioxidant vitamin C prevents decline in endothelial function during sitting |
| Q46653279 | Antioxidants, endothelial dysfunction, and DCS: in vitro and in vivo study |
| Q47211102 | Apocynin combined with drugs as coadjuvant could be employed to prevent and/or treat the chronic kidney disease |
| Q46383874 | Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production. |
| Q50294469 | Ascorbate can reduce the BH3 radical back to BH4 |
| Q36479728 | Ascorbic acid prevents VEGF-induced increases in endothelial barrier permeability |
| Q38742663 | Ascorbic acid repletion: A possible therapy for diabetic macular edema? |
| Q28075206 | Asymmetric Dimethylarginine Is a Well Established Mediating Risk Factor for Cardiovascular Morbidity and Mortality-Should Patients with Elevated Levels Be Supplemented with Citrulline? |
| Q92973619 | Beneficial Effects of Vitamins K and D3 on Redox Balance of Human Osteoblasts Cultured with Hydroxyapatite-Based Biomaterials |
| Q35221390 | Blockade of NADPH oxidase restores vasoreparative function in diabetic CD34+ cells |
| Q41389538 | Brachial artery flow-mediated dilation following exercise with augmented oscillatory and retrograde shear rate |
| Q50045987 | Caloric restriction increases free radicals and inducible nitric oxide synthase expression in mice infected with Salmonella Typhimurium. |
| Q89976543 | Cannabidiol Effects on Phospholipid Metabolism in Keratinocytes from Patients with Psoriasis Vulgaris |
| Q92422872 | Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation |
| Q99629126 | Cannabidiol protects keratinocyte cell membranes following exposure to UVB and hydrogen peroxide |
| Q35073570 | Cardiac-specific overexpression of GTP cyclohydrolase 1 restores ischaemic preconditioning during hyperglycaemia |
| Q26751288 | Cellular and molecular mechanisms of endothelial ischemia/reperfusion injury: perspectives and implications for postischemic myocardial protection |
| Q36687957 | Cellular mechanisms and signalling pathways activated by high glucose and AGE-albumin in the aortic endothelium |
| Q46262615 | Chemical Probes for Redox Signaling and Oxidative Stress. |
| Q36098306 | Chronic ethanol ingestion increases nitric oxide production in the lung |
| Q41966707 | Chronic oral supplementation with sepiapterin prevents endothelial dysfunction and oxidative stress in small mesenteric arteries from diabetic (db/db) mice |
| Q44016035 | Chronic therapy with isosorbide-5-mononitrate causes endothelial dysfunction, oxidative stress, and a marked increase in vascular endothelin-1 expression. |
| Q37875591 | Clinical science review article: understanding the implications of diabetes on the vascular system |
| Q38712571 | Comparison of protective effect of ascorbic acid on redox and endocannabinoid systems interactions in in vitro cultured human skin fibroblasts exposed to UV radiation and hydrogen peroxide |
| Q36011653 | Correlations between Endothelial Functions and ROS Detection in Diabetic Microvascular Wall: Early and Late Ascorbic Acid Supplementation |
| Q37825577 | Critical role for oxidative stress, platelets, and coagulation in capillary blood flow impairment in sepsis |
| Q28391403 | Cross talk between mitochondria and NADPH oxidases |
| Q38667506 | Crosstalk of mitochondria with NADPH oxidase via reactive oxygen and nitrogen species signalling and its role for vascular function. |
| Q36853413 | Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice |
| Q37420916 | Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics |
| Q36196910 | Cytoprotective and antioxidant effects of human lactoferrin against H2O2-induced oxidative stress in human umbilical vein endothelial cells |
| Q42873004 | Cytotoxic dendritic cells generated from cancer patients. |
| Q36109424 | Decreased arteriolar tetrahydrobiopterin is linked to superoxide generation from nitric oxide synthase in mice fed high salt |
| Q35543543 | Decreased tetrahydrobiopterin and disrupted association of Hsp90 with eNOS by hyperglycemia impair myocardial ischemic preconditioning |
| Q45015147 | Detection of intracellular superoxide formation in endothelial cells and intact tissues using dihydroethidium and an HPLC-based assay |
| Q92343929 | Development of calcific aortic valve disease: Do we know enough for new clinical trials? |
| Q43267895 | Dihydrofolate reductase and biopterin recycling in cardiovascular disease |
| Q26800052 | Disturbed Amino Acid Metabolism in HIV: Association with Neuropsychiatric Symptoms |
| Q42451294 | Does Nitric Oxide Mediate the Vasodilator Activity of Nitroglycerin? |
| Q53743021 | Does endothelial tetrahydrobiopterin control the endothelial NO synthase coupling state in arterial resistance arteries? |
| Q33815495 | Dose dependent effects of reactive oxygen and nitrogen species on the function of neuronal nitric oxide synthase |
| Q37357272 | Dysregulation of antioxidant mechanisms contributes to increased oxidative stress in calcific aortic valvular stenosis in humans. |
| Q34409347 | EPR detection of cellular and mitochondrial superoxide using cyclic hydroxylamines. |
| Q35070086 | Early determinants of H2O2-induced endothelial dysfunction |
| Q37662353 | Effect of acute xanthine oxidase inhibition on myocardial energetics during basal and very high cardiac workstates |
| Q54267709 | Effect of ascorbic acid deficiency on catecholamine synthesis in adrenal glands of SMP30/GNL knockout mice. |
| Q39125227 | Effect of novel dinuclear platinum(II) complexes on redox status of MOLT-4 leukemic cells. |
| Q36940593 | Effects of Diabetes on Salivary Gland Protein Expression of Tetrahydrobiopterin and Nitric Oxide Synthesis and Function |
| Q38741534 | Effects of noise on vascular function, oxidative stress, and inflammation: mechanistic insight from studies in mice. |
| Q36132556 | Effects of p67phox on the mitochondrial oxidative state in the kidney of Dahl salt-sensitive rats: optical fluorescence 3-D cryoimaging |
| Q42142797 | Effects of tetrahydrobiopterin oral treatment in hypoxia-induced pulmonary hypertension in rat. |
| Q45096402 | Endostatin uncouples NO and Ca2+ response to bradykinin through enhanced O2*- production in the intact coronary endothelium |
| Q46280838 | Endothelial Cell Reactive Oxygen Species and Ca2+ Signaling in Pulmonary Hypertension |
| Q36593434 | Endothelial Nitric Oxide Synthase-Derived Nitric Oxide Prevents Dihydrofolate Reductase Degradation via Promoting S-Nitrosylation |
| Q35947546 | Endothelial dysfunction and diabetes: effects on angiogenesis, vascular remodeling, and wound healing |
| Q37698976 | Endothelial dysfunction and enhanced contractility in microvessels from ovariectomized rats: roles of oxidative stress and perivascular adipose tissue |
| Q38042870 | Endothelial dysfunction and hypertension in aging |
| Q34535079 | Endothelial dysfunction in the microcirculation of patients with obstructive sleep apnea |
| Q37042021 | Endothelial dysfunction: the early predictor of atherosclerosis. |
| Q35086889 | Endothelial function in obstructive sleep apnea |
| Q37863567 | Endothelial mechanisms of endothelial dysfunction in patients with obstructive sleep apnea |
| Q30351081 | Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation. |
| Q34980336 | Endothelial nitric oxide synthase uncoupling: a novel pathway in OSA induced vascular endothelial dysfunction |
| Q38597218 | Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms |
| Q33812887 | Essential hypertension and oxidative stress: New insights |
| Q36141348 | Evaluating oxidative stress in human cardiovascular disease: methodological aspects and considerations |
| Q37285389 | Evidence of endothelial dysfunction in the development of Alzheimer's disease: Is Alzheimer's a vascular disorder? |
| Q28256495 | Free radical production by dysfunctional eNOS |
| Q37923503 | Free radicals and antioxidants at a glance using EPR spectroscopy |
| Q36050521 | Free radicals and antioxidants in cardiovascular diseases. |
| Q37235626 | GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function |
| Q36057680 | Glutathione in cerebral microvascular endothelial biology and pathobiology: implications for brain homeostasis |
| Q36040759 | HIV-1, reactive oxygen species, and vascular complications |
| Q42576287 | HPLC analysis of tetrahydrobiopterin and its pteridine derivatives using sequential electrochemical and fluorimetric detection: application to tetrahydrobiopterin autoxidation and chemical oxidation |
| Q90255365 | High Vitamin C Status Is Associated with Elevated Mood in Male Tertiary Students |
| Q38537945 | Homocysteine, methylenetetrahydrofolate reductase, folate status and atherothrombosis: A mechanistic and clinical perspective |
| Q36954777 | Honokiol is a potent scavenger of superoxide and peroxyl radicals |
| Q36521250 | Hyperglycemia in acute ischemic stroke: a vascular perspective. |
| Q36617640 | In utero exposure to benzo(a)pyrene predisposes offspring to cardiovascular dysfunction in later-life. |
| Q28391612 | In vitro assessments of nanomaterial toxicity |
| Q44612933 | In vivo expression and function of recombinant GTPCH I in the rabbit carotid artery |
| Q23914693 | Increased oxidant activity mediates vascular dysfunction in vibration injury |
| Q36662476 | Inducible nitric oxide synthase deficiency protects the heart from systolic overload-induced ventricular hypertrophy and congestive heart failure. |
| Q33748662 | Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea |
| Q34283413 | Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II |
| Q34897476 | Is peroxisome proliferator-activated receptor gamma (PPARγ) a therapeutic target for the treatment of pulmonary hypertension? |
| Q36666934 | Janus-faced role of endothelial NO synthase in vascular disease: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal |
| Q92550885 | L-sepiapterin restores SLE serum-induced markers of endothelial function in endothelial cells |
| Q37038944 | Laminar shear stress inhibits lipid peroxidation induced by high glucose plus arachidonic acid in endothelial cells |
| Q43249652 | Lesions and lipids and radicals--O my! |
| Q35085577 | Loss of NRF2 impairs gastric nitrergic stimulation and function |
| Q57033030 | Loss of cAMP-dependent stimulation of isolated cilia motility by alcohol exposure is oxidant dependent |
| Q36012674 | Measurement of reactive oxygen species in cardiovascular studies |
| Q36753476 | Mechanisms and consequences of endothelial nitric oxide synthase dysfunction in hypertension |
| Q39290225 | Mechanisms of ascorbic acid stimulation of norepinephrine synthesis in neuronal cells |
| Q37145667 | Mechanisms of endothelial dysfunction in obstructive sleep apnea |
| Q33929661 | Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus. |
| Q36282826 | Melatonin and nitric oxide: two required antagonists for mitochondrial homeostasis |
| Q57492137 | Metabolomics-Driven Elucidation of Cellular Nitrate Tolerance Reveals Ascorbic Acid Prevents Nitroglycerin-Induced Inactivation of Xanthine Oxidase |
| Q25257578 | Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies |
| Q35944831 | Mitochondria: redox metabolism and dysfunction |
| Q26799985 | Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction |
| Q35252245 | Modeling of biopterin-dependent pathways of eNOS for nitric oxide and superoxide production. |
| Q42964432 | Modeling of the in vivo kinetics of antioxidants delineates suitable parameters for selecting potential antioxidant adjuvants for cancer therapy |
| Q37881801 | Modulating endothelial nitric oxide synthase: a new cardiovascular therapeutic strategy |
| Q26770958 | Modulation of Radiation Response by the Tetrahydrobiopterin Pathway |
| Q38599441 | Multiple therapeutic effect of endothelial progenitor cell regulated by drugs in diabetes and diabetes related disorder. |
| Q39340905 | Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme |
| Q36002621 | Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4. |
| Q34636226 | Myocardial oxidative stress contributes to transgenic β₂-adrenoceptor activation-induced cardiomyopathy and heart failure. |
| Q31145647 | NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy |
| Q46522534 | NADPH Oxidase Plays a Role on Ethanol-Induced Hypertension and Reactive Oxygen Species Generation in the Vasculature. |
| Q30475784 | NO/redox disequilibrium in the failing heart and cardiovascular system |
| Q28077204 | Neuronal nitric oxide synthase in hypertension - an update |
| Q60919681 | New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease |
| Q54344856 | New role for L-arginine in regulation of inducible nitric-oxide-synthase-derived superoxide anion production in raw 264.7 macrophages. |
| Q58863636 | Nitric Oxide, Oxidative Stress, Immune Response and Critical Care |
| Q41127967 | Nitric oxide and cancer |
| Q38605600 | Nitric oxide and cardiovascular risk factors. |
| Q37556067 | Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart |
| Q37715827 | Nitric oxide and oxidative stress in vascular disease |
| Q24645400 | Nitric oxide and peroxynitrite in health and disease |
| Q41584845 | Nitric oxide fails to confer endogenous antiarrhythmic cardioprotection in the primate heart in vitro. |
| Q34085550 | Nitric oxide synthase 3 contributes to ventilator-induced lung injury |
| Q28389655 | Nitric oxide synthase: "enzyme zero" in air pollution-induced vascular toxicity |
| Q36481074 | Nitric oxide/redox-based signalling as a therapeutic target for penile disorders |
| Q37887771 | Nitric oxide: a guardian for vascular grafts? |
| Q42544768 | Nitroglycerin-induced S-nitrosylation and desensitization of soluble guanylyl cyclase contribute to nitrate tolerance |
| Q35746663 | Nitrotyrosine as a marker for peroxynitrite-induced neurotoxicity: the beginning or the end of the end of dopamine neurons? |
| Q35848552 | Novel strategies to ameliorate radiation injury: a possible role for tetrahydrobiopterin |
| Q36684472 | Novel therapies targeting vascular endothelium |
| Q33649858 | Nox5 and the regulation of cellular function |
| Q34762233 | Oral sapropterin acutely augments reflex vasodilation in aged human skin through nitric oxide-dependent mechanisms |
| Q41957529 | Oral tetrahydrobiopterin improves the beneficial effect of adenoviral-mediated eNOS gene transfer after induction of hindlimb ischemia |
| Q26799354 | Organic Nitrate Therapy, Nitrate Tolerance, and Nitrate-Induced Endothelial Dysfunction: Emphasis on Redox Biology and Oxidative Stress |
| Q44575257 | Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion |
| Q33743649 | Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load |
| Q55334091 | Oxidative Stress in Preeclampsia and Placental Diseases. |
| Q37867946 | Oxidative stress and endothelial dysfunction in hypertension |
| Q37834017 | Oxidative stress and endothelial dysfunction: therapeutic implications |
| Q34038044 | Oxidative stress and metabolic pathologies: from an adipocentric point of view. |
| Q35054170 | Oxidative stress contributes to large elastic arterial stiffening across the stages of the menopausal transition |
| Q37003803 | Oxidative stress in diabetic nephropathy |
| Q89094063 | Oxidative stress induces BH4 deficiency in male, but not female, SHR |
| Q26747626 | Oxidative-Nitrosative Stress and Myocardial Dysfunctions in Sepsis: Evidence from the Literature and Postmortem Observations |
| Q38022767 | Oxidized low density lipoprotein, stem cells, and atherosclerosis |
| Q34154030 | Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway |
| Q37166505 | Oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine induces vascular endothelial superoxide production: implication of NADPH oxidase |
| Q37689190 | PPARgamma as a potential therapeutic target in pulmonary hypertension |
| Q34829361 | Pentaerythritol tetranitrate improves angiotensin II-induced vascular dysfunction via induction of heme oxygenase-1. |
| Q37174305 | Peripheral mechanisms of thermoregulatory control of skin blood flow in aged humans |
| Q35888585 | Peroxynitrite and vascular endothelial dysfunction in diabetes mellitus. |
| Q50294466 | Peroxynitrite can oxidise BH4 to the BH3 radical |
| Q37660941 | Peroxynitrite disrupts endothelial caveolae leading to eNOS uncoupling and diminished flow-mediated dilation in coronary arterioles of diabetic patients. |
| Q33775518 | Peroxynitrite induces destruction of the tetrahydrobiopterin and heme in endothelial nitric oxide synthase: transition from reversible to irreversible enzyme inhibition |
| Q36431848 | Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo |
| Q46706026 | Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice |
| Q29615424 | Peroxynitrite: biochemistry, pathophysiology and development of therapeutics |
| Q46184389 | Physiological Levels of Nitric Oxide Diminish Mitochondrial Superoxide. Potential Role of Mitochondrial Dinitrosyl Iron Complexes and Nitrosothiols |
| Q39540776 | Piper Sarmentosum Increases Nitric Oxide Production in Oxidative Stress: A Study on Human Umbilical Vein Endothelial Cells |
| Q36403729 | Prevention of lethal murine pancreas ischemia reperfusion injury is specific for tetrahydrobiopterin |
| Q35792798 | Production of extracellular superoxide by human lymphoblast cell lines: comparison of electron spin resonance techniques and cytochrome C reduction assay |
| Q39916287 | Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression |
| Q34762292 | ROS-responsive microspheres for on demand antioxidant therapy in a model of diabetic peripheral arterial disease. |
| Q42948306 | Rapid aldosterone signaling and vascular reactivity: relax or don't do it. |
| Q37294875 | Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS. |
| Q37342840 | Reactions of peroxynitrite with uric acid: formation of reactive intermediates, alkylated products and triuret, and in vivo production of triuret under conditions of oxidative stress |
| Q33855335 | Reactive oxygen species (ROS) from NADPH and xanthine oxidase modulate the cutaneous local heating response in healthy humans |
| Q37097141 | Reactive oxygen species and glucocorticoid-induced hypertension |
| Q36440894 | Recent advances in understanding endothelial dysfunction in atherosclerosis |
| Q26822833 | Recoupling the cardiac nitric oxide synthases: tetrahydrobiopterin synthesis and recycling |
| Q38202879 | Redox mechanisms in regulation of adipocyte differentiation: beyond a general stress response |
| Q35666358 | Redox processes underlying the vascular repair reaction |
| Q92125180 | Redox regulation of motile cilia in airway disease |
| Q33689229 | Redox signaling, vascular function, and hypertension |
| Q46249417 | Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration. |
| Q38383375 | Redox-sensitive mechanisms underlying vascular dysfunction in heart failure |
| Q37692538 | Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late-stage atherosclerosis |
| Q37719406 | Reversal of SIN-1-induced eNOS dysfunction by the spin trap, DMPO, in bovine aortic endothelial cells via eNOS phosphorylation |
| Q44887381 | Role of tetrahydrobiopterin in adrenocorticotropic hormone-induced hypertension in the rat. |
| Q37406657 | Role of vitamin C in the function of the vascular endothelium |
| Q41994308 | Rutin as a Mediator of Lipid Metabolism and Cellular Signaling Pathways Interactions in Fibroblasts Altered by UVA and UVB Radiation. |
| Q90163923 | S-Nitrosylation: An Emerging Paradigm of Redox Signaling |
| Q35172025 | S-nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats |
| Q33769535 | SOD3 and eNOS genotypes are associated with SOD activity and NOx |
| Q37405010 | Selective recapitulation of conserved and nonconserved regions of putative NOXA1 protein activation domain confers isoform-specific inhibition of Nox1 oxidase and attenuation of endothelial cell migration |
| Q37199274 | Selective up-regulation of arginase-1 in coronary arteries of diabetic patients |
| Q35217368 | Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase |
| Q36948888 | Septic impairment of capillary blood flow requires nicotinamide adenine dinucleotide phosphate oxidase but not nitric oxide synthase and is rapidly reversed by ascorbate through an endothelial nitric oxide synthase-dependent mechanism |
| Q35839144 | Serine 1179 Phosphorylation of Endothelial Nitric Oxide Synthase Increases Superoxide Generation and Alters Cofactor Regulation |
| Q58075704 | Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation |
| Q55154166 | Structural alterations in rat myocardium induced by chronic l-arginine and l-NAME supplementation. |
| Q36122763 | Sympathetic control of reflex cutaneous vasoconstriction in human aging |
| Q34252918 | Systemic and vascular oxidation limits the efficacy of oral tetrahydrobiopterin treatment in patients with coronary artery disease |
| Q92511912 | T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of ·NO/cGMP Signaling |
| Q37968218 | Tackling endothelial dysfunction by modulating NOS uncoupling: new insights into its pathogenesis and therapeutic possibilities |
| Q37416432 | Targeted detoxification of selected reactive oxygen species in the vascular endothelium |
| Q38029695 | Targeted interception of signaling reactive oxygen species in the vascular endothelium |
| Q38808467 | Targeting the NO/superoxide ratio in adipose tissue: relevance to obesity and diabetes management |
| Q36714071 | Tetrahydrobiopterin Supplementation Improves Endothelial Function But Does Not Alter Aortic Stiffness in Patients With Rheumatoid Arthritis |
| Q40536337 | Tetrahydrobiopterin Supplementation Improves Phenylalanine Metabolism in a Murine Model of Severe Malaria. |
| Q33711785 | Tetrahydrobiopterin does not affect end-organ responsiveness to norepinephrine-mediated vasoconstriction in aged skin |
| Q35850060 | Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women |
| Q33687812 | Tetrahydrobiopterin in cardiovascular health and disease |
| Q34495148 | Tetrahydrobiopterin increases NO-dependent vasodilation in hypercholesterolemic human skin through eNOS-coupling mechanisms |
| Q36434380 | Tetrahydrobiopterin, L-arginine and vitamin C act synergistically to decrease oxidant stress and increase nitric oxide that increases blood flow recovery after hindlimb ischemia in the rat. |
| Q36071695 | Tetrahydrobiopterin, L-arginine and vitamin C actsynergistically to decrease oxidative stress, increase nitricoxide and improve blood flow after induction of hindlimbischemia in the rat. |
| Q46716730 | Tetrahydrobiopterin: a novel antihypertensive therapy |
| Q60616987 | The 894G > T (Glu298Asp) Variant in the Endothelial NOS Gene and MTHFR Polymorphisms Influence Homocysteine Levels in Patients with Cognitive Decline |
| Q58710605 | The Effect of Sea Buckthorn ( L.) Seed Oil on UV-Induced Changes in Lipid Metabolism of Human Skin Cells |
| Q60154493 | The Measurement of Nitric Oxide Production by Cultured Endothelial Cells |
| Q35751821 | The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression. |
| Q47643546 | The adverse effects of environmental noise exposure on oxidative stress and cardiovascular risk. |
| Q62078862 | The eNOS cofactor tetrahydrobiopterin improves endothelial dysfunction in livers of rats with CCl4 cirrhosis |
| Q37198569 | The enigma of nitroglycerin bioactivation and nitrate tolerance: news, views and troubles |
| Q36347434 | The inhibitory effect of S-nitrosoglutathione on blood-brain barrier disruption and peroxynitrite formation in a rat model of experimental stroke |
| Q38103265 | The regulation of vascular tetrahydrobiopterin bioavailability |
| Q36202755 | The role of nitric oxide synthase-derived reactive oxygen species in the altered relaxation of pulmonary arteries from lambs with increased pulmonary blood flow. |
| Q62647447 | The role of oxidant stress in angiotensin II-mediated contraction of human resistance arteries in the state of health and the presence of cardiovascular disease |
| Q37828059 | The role of oxidative stress in the pathophysiology of hypertension |
| Q35925357 | The role of peroxisome proliferator-activated receptors in pulmonary vascular disease |
| Q37362748 | The role of the L-arginine-nitric oxide pathway in preeclampsia |
| Q45302714 | The short-term consumption of a moderately high-fat diet alters nitric oxide bioavailability in lean female Zucker rats |
| Q35888589 | The two faces of endothelial nitric oxide synthase in the pathophysiology of atherosclerosis |
| Q35216447 | Therapeutic effect of enhancing endothelial nitric oxide synthase (eNOS) expression and preventing eNOS uncoupling |
| Q44912900 | Three different oxygen-induced radical species in endothelial nitric-oxide synthase oxygenase domain under regulation by L-arginine and tetrahydrobiopterin |
| Q42291320 | Time-dependent effect of rutin on skin fibroblasts membrane disruption following UV radiation. |
| Q50777107 | Tobacco smoke dysregulates endothelial vasoregulatory transcripts in vivo. |
| Q64067785 | Tocomin Restores Endothelium-Dependent Relaxation in the Diabetic Rat Aorta by Increasing NO Bioavailability and Improving the Expression of eNOS |
| Q33693287 | Tryptophan Metabolism in Allergic Disorders |
| Q36519821 | Type 2 diabetes restricts multipotency of mesenchymal stem cells and impairs their capacity to augment postischemic neovascularization in db/db mice |
| Q34150616 | Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling |
| Q46842392 | Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species |
| Q35610656 | Vascular Aging across the Menopause Transition in Healthy Women |
| Q35766136 | Vascular dysfunction and chronic obstructive pulmonary disease: the role of redox balance |
| Q35227188 | Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy |
| Q26779400 | Vascular nitric oxide: Beyond eNOS |
| Q37087728 | Vascular protection by tetrahydrobiopterin: progress and therapeutic prospects |
| Q43943995 | Vitamin C prevents the acute decline of flow-mediated dilation after altered shear rate patterns |
| Q24617202 | Vitamins C and E: beneficial effects from a mechanistic perspective |
| Q83499224 | [Physical activity and endothelial dysfunction in type 2 diabetic patients: the role of nitric oxide and oxidative stress] |
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