Hepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytes

scientific article

Hepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/JVI.00900-10
P932PMC publication ID2953153
P698PubMed publication ID20810735

P50authorSrikanta DashQ96901165
Shubham ShrivastavaQ55190822
Tatsuo KandaQ61112129
Ratna B RayQ90724777
Ranjit RayQ91328963
P2093author name stringRobert Steele
Amit Raychoudhuri
P2860cites workHCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell linesQ24295166
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunityQ24296473
Hepatitis C virus expression suppresses interferon signaling by degrading STAT1Q24300002
PKR protein kinase is activated by hepatitis C virus and inhibits viral replication through translational controlQ24336050
Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanismsQ24548483
Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-IQ24556673
DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infectionQ27469850
Human MxA protein confers resistance to Semliki Forest virus and inhibits the amplification of a Semliki Forest virus-based replicon in the absence of viral structural proteinsQ27472518
Viral and immunological determinants of hepatitis C virus clearance, persistence, and diseaseQ27473001
Generation of Infectious Hepatitis C Virus in Immortalized Human HepatocytesQ27473215
Replication of Hepatitis C Virus (HCV) RNA in Mouse Embryonic Fibroblasts: Protein Kinase R (PKR)-Dependent and PKR-Independent Mechanisms for Controlling HCV RNA Replication and Mediating Interferon ActivitiesQ27477459
Hepatitis C Virus Infection Induces the Beta Interferon Signaling Pathway in Immortalized Human HepatocytesQ27485023
Interferon signaling and treatment outcome in chronic hepatitis CQ27486083
Toll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma CellsQ27489687
Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathwayQ27491011
The prevalence of hepatitis C virus infection in the United States, 1999 through 2002Q29619974
Viruses and interferonsQ29620788
Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylationQ34000124
Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytesQ34398825
Mechanism of interferon action: Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated kinase processing site specificity similar to hemin-regulated rabbit reticulocyte kinaseQ34555781
Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinaseQ36039597
Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expressionQ36351976
Unphosphorylated STAT1 prolongs the expression of interferon-induced immune regulatory genesQ37206449
Intrahepatic gene expression during chronic hepatitis C virus infection in chimpanzeesQ37683158
Interferon-Induced Antiviral Actions and Their RegulationQ40484830
IFN-alpha antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling-3.Q40674809
Hepatitis C virus (HCV) core protein-induced, monocyte-mediated mechanisms of reduced IFN-alpha and plasmacytoid dendritic cell loss in chronic HCV infection.Q43033205
Upregulation of endogenous intrahepatic interferon stimulated genes during chronic hepatitis C virus infectionQ43048844
Intrahepatic MxA and PKR protein expression in chronic hepatitis C virus infectionQ43527754
Interferon-alpha therapy does not modulate hepatic expression of classical type I interferon inducible genesQ43692671
Mx proteins: mediators of innate resistance to RNA virusesQ47932415
P433issue21
P407language of work or nameEnglishQ1860
P921main subjecthepatitis CQ154869
Hepatitis C virusQ708693
P304page(s)10991-10998
P577publication date2010-09-01
P1433published inJournal of VirologyQ1251128
P1476titleHepatitis C virus infection impairs IRF-7 translocation and Alpha interferon synthesis in immortalized human hepatocytes
P478volume84