Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE

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Malignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1028003925
P356DOI10.1186/1476-4598-9-254
P932PMC publication ID2955615
P698PubMed publication ID20860785
P5875ResearchGate publication ID46402829

P50authorThorsten StieweQ56528724
Albert SickmannQ28211405
P2093author name stringStephanie M Pütz
Fotini Vogiatzi
P2860cites workHuman breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.Q35076272
Heat shock protein 90 as a molecular target for cancer therapeuticsQ35099516
Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth controlQ35539933
The urokinase plasminogen activator system: role in malignancyQ35644332
The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2.Q36263571
Protein detection methods in proteomics researchQ36285054
Redox regulation of precursor cell function: insights and paradoxesQ36342622
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengtheningQ36449812
Identification of the functional role of peroxiredoxin 6 in the progression of breast cancerQ36465265
Two-dimensional electrophoresis of membrane proteins.Q36902896
p73 poses a barrier to malignant transformation by limiting anchorage-independent growthQ38294005
Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network.Q40063505
Biological and clinical aspects of plasminogen activator inhibitor type 2.Q40378014
Proteomic analysis of selected prognostic factors of breast cancer.Q40527843
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cellsQ40572608
Immortalization and transformation of primary human airway epithelial cells by gene transfer.Q40722115
Critical role for SV40 small-t antigen in human cell transformationQ40746221
Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytomaQ46338106
Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras.Q52118219
Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.Q52165691
A genetically tractable model of human glioma formation.Q52542891
Ruthenium (II) tris-bathophenanthroline disulfonate is well suitable for Tris-Glycine PAGE but not for Bis-Tris gelsQ55884760
The tumor-suppressive functions of the human INK4A locusQ57187959
A simple assay for quantification of protein in tissue sections, cell cultures, and cell homogenates, and of protein immobilized on solid surfacesQ73094316
Immunohistochemical detection of uroplakin III, cytokeratin 7, and cytokeratin 20 in canine urothelial tumorsQ73103242
Opinion: Comparative biology of mouse versus human cells: modelling human cancer in miceQ75312804
Current two-dimensional electrophoresis technology for proteomicsQ22252855
Proteomic analysis of p16ink4a-binding proteinsQ24298437
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4aQ24324559
Extension of life-span by introduction of telomerase into normal human cellsQ24336088
High resolution two-dimensional electrophoresis of proteinsQ24608190
Cluster analysis and display of genome-wide expression patternsQ24644463
A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shockQ24648784
Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motifQ24682801
Specific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
Creation of human tumour cells with defined genetic elementsQ28141602
Protein mapping by combined isoelectric focusing and electrophoresis of mouse tissues. A novel approach to testing for induced point mutations in mammalsQ28143353
A comparison between Sypro Ruby and ruthenium II tris (bathophenanthroline disulfonate) as fluorescent stains for protein detection in gelsQ28202225
Improved Ruthenium II tris (bathophenantroline disulfonate) staining and destaining protocol for a better signal-to-background ratio and improved baseline resolutionQ28248103
Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolismQ28250381
SV40 large T antigen targets multiple cellular pathways to elicit cellular transformationQ28282761
Annexin 2 binding to phosphatidylinositol 4,5-bisphosphate on endocytic vesicles is regulated by the stress response pathwayQ28583310
Towards a high resolution separation of human cerebrospinal fluid.Q30708834
About the mechanism of interference of silver staining with peptide mass spectrometry.Q33200410
Proteomics-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinomaQ33262742
Protein profiling by the combination of two independent mass spectrometry techniques.Q33280961
Silver- and Coomassie-staining protocols: detection limits and compatibility with ESI MS.Q33285278
Proteomics analysis of H-RAS-mediated oncogenic transformation in a genetically defined human ovarian cancer modelQ33947451
Enumeration of the simian virus 40 early region elements necessary for human cell transformationQ34117528
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation.Q34345750
Cancer modeling in the modern era: progress and challengesQ34520417
P304page(s)254
P577publication date2010-09-22
P1433published inMolecular CancerQ15724585
P1476titleMalignant transformation in a defined genetic background: proteome changes displayed by 2D-PAGE
P478volume9

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cites work (P2860)
Q36798968Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model
Q39357652Proteomic investigation of anti‐tumor activities exerted by sinularin against A2058 melanoma cells
Q37979012TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 inhibitors

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