| scholarly article | Q13442814 |
| P50 | author | William C Hahn | Q88192808 |
| Robert Weinberg | Q701506 | ||
| David M. Sabatini | Q16231524 | ||
| P2093 | author name string | James A DeCaprio | |
| Scott K Dessain | |||
| Jessie E King | |||
| Brian Elenbaas | |||
| Mary W Brooks | |||
| P2860 | cites work | Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span | Q74311298 |
| Functional expression of human PP2Ac in yeast permits the identification of novel C-terminal and dominant-negative mutant forms | Q78122298 | ||
| Identification of structural elements involved in the interaction of simian virus 40 small tumor antigen with protein phosphatase 2A | Q22008557 | ||
| Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a | Q24324559 | ||
| Extension of life-span by introduction of telomerase into normal human cells | Q24336088 | ||
| Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling | Q24532278 | ||
| Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
| p53, the cellular gatekeeper for growth and division | Q27860990 | ||
| Creation of human tumour cells with defined genetic elements | Q28141602 | ||
| Alterations of the PPP2R1B Gene in Human Lung and Colon Cancer | Q28284845 | ||
| The complexity of p53 modulation: emerging patterns from divergent signals | Q28284854 | ||
| A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma | Q28296086 | ||
| Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha | Q28506401 | ||
| A role for both RB and p53 in the regulation of human cellular senescence | Q64378339 | ||
| Cellular proteins that are targetted by DNA tumor viruses for transformation | Q64379411 | ||
| The SV40 small t antigen is essential for the morphological transformation of human fibroblasts | Q69515235 | ||
| In vitro mutagenesis of a putative DNA binding domain of SV40 large-T | Q72399727 | ||
| Low frequency of alterations of the alpha (PPP2R1A) and beta (PPP2R1B) isoforms of the subunit A of the serine-threonine phosphatase 2A in human neoplasms | Q73540311 | ||
| Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line | Q29547239 | ||
| Regulation of retinoblastoma protein functions by ectopic expression of human cyclins | Q29618320 | ||
| Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF | Q29619663 | ||
| The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens | Q31167810 | ||
| Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene | Q33557109 | ||
| Regulation of protein kinase cascades by protein phosphatase 2A. | Q33632946 | ||
| The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins. | Q33772346 | ||
| Simian virus 40 small tumor antigen and an amino-terminal domain of large tumor antigen share a common transforming function | Q33812137 | ||
| Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death | Q33876302 | ||
| Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology | Q33912829 | ||
| Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics | Q33962085 | ||
| The role of the SV40 ST antigen in cell growth promotion and transformation | Q34177954 | ||
| Cellular transformation by SV40 large T antigen: interaction with host proteins | Q34177960 | ||
| Role of T antigen interactions with p53 in tumorigenesis | Q34177970 | ||
| Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. | Q34181194 | ||
| Hypervariable ultra-long telomeres in mice | Q34195724 | ||
| Monoclonal antibodies specific for simian virus 40 tumor antigens | Q34249232 | ||
| Developmental and tissue-specific regulation of mouse telomerase and telomere length | Q34265760 | ||
| The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation. | Q34345750 | ||
| Senescence as a mode of tumor suppression | Q35034137 | ||
| Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. | Q35076272 | ||
| Interactions of HPV E6 and E7 oncoproteins with tumour suppressor gene products | Q35230893 | ||
| Structure and function of simian virus 40 large tumor antigen | Q35231378 | ||
| Can ends justify the means?: Telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells | Q36070936 | ||
| Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening | Q36449812 | ||
| Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation | Q36555544 | ||
| The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain. | Q36570729 | ||
| Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. | Q36571152 | ||
| Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations | Q36685815 | ||
| Transformation of a continuous rat embryo fibroblast cell line requires three separate domains of simian virus 40 large T antigen | Q36697268 | ||
| Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding | Q36706865 | ||
| Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization | Q36754020 | ||
| Requirement for the simian virus 40 small tumor antigen in tumorigenesis in transgenic mice | Q36793491 | ||
| The large tumor antigen of simian virus 40 encodes at least two distinct transforming functions | Q36832483 | ||
| Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens | Q36912292 | ||
| Activated Ha-ras can cooperate with defective simian virus 40 in the transformation of nonestablished rat embryo fibroblasts | Q36917280 | ||
| Mutational Analysis of Simian Virus 40 T Antigen: Isolation and Characterization of Mutants with Deletions in the T-Antigen Gene | Q36936356 | ||
| Defining the molecular mechanisms of human cell immortalization | Q37173111 | ||
| Human mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicity. | Q37432550 | ||
| Construction and analysis of viable deletion mutants of simian virus 40 | Q37502779 | ||
| Resistance of human cells to tumorigenesis induced by cloned transforming genes | Q37690837 | ||
| The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses | Q37855772 | ||
| Malignant transformation of human fibroblasts by oncogene transfection or carcinogen treatment | Q37941619 | ||
| Telomerase activity is sufficient to allow transformed cells to escape from crisis | Q39444785 | ||
| pRB-dependent, J domain-independent function of simian virus 40 large T antigen in override of p53 growth suppression | Q39589009 | ||
| p16INK4A Participates in a G1 Arrest Checkpoint in Response to DNA Damage | Q39631343 | ||
| Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP). | Q39720480 | ||
| Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation | Q40039575 | ||
| The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest. | Q40041446 | ||
| Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells | Q40158462 | ||
| The roles of the simian virus 40 tumor antigens in transformation of chinese hamster lung cells | Q40251500 | ||
| Nucleotide sequence deletions within the coding region for small-t antigen of simian virus 40 | Q40254367 | ||
| Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene | Q40273505 | ||
| Derivation of human tumor cells in vitro without widespread genomic instability | Q40762000 | ||
| Independent expression of the transforming amino-terminal domain of SV40 large I antigen from an alternatively spliced third SV40 early mRNA. | Q40875168 | ||
| Expression of catalytically active telomerase does not prevent premature senescence caused by overexpression of oncogenic Ha-Ras in normal human fibroblasts | Q40961777 | ||
| Absence of cancer-associated changes in human fibroblasts immortalized with telomerase | Q40978424 | ||
| Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells | Q41154447 | ||
| The three transforming regions of SV40 T antigen are required for immortalization of primary mouse embryo fibroblasts | Q41260491 | ||
| Mechanism of HPV E6 proteins in cellular transformation | Q41585225 | ||
| Role of the retinoblastoma protein in the pathogenesis of human cancer | Q41639462 | ||
| p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts | Q41654913 | ||
| Human endothelial cell life extension by telomerase expression | Q41688544 | ||
| Viral transactivating proteins | Q41689449 | ||
| Dissociation of Rb-binding and anchorage-independent growth from immortalization and tumorigenicity using SV40 mutants producing N-terminally truncated large T antigens | Q41723309 | ||
| Control of protein phosphatase 2A by simian virus 40 small-t antigen | Q41814391 | ||
| SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen | Q42809173 | ||
| Mutants with changes within or near a hydrophobic region of simian virus 40 large tumor antigen are defective for binding cellular protein p53. | Q44625528 | ||
| Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells. | Q44816904 | ||
| New HPV E6 binding proteins: dangerous liaisons? | Q48009241 | ||
| A genetically tractable model of human glioma formation. | Q52542891 | ||
| Induction of immortality is an early event in malignant transformation of mammalian cells by carcinogens | Q53563956 | ||
| Role of small t antigen in the acute transforming activity of SV40 | Q53564452 | ||
| Escape from premature senescence is not sufficient for oncogenic transformation by Ras. | Q54021692 | ||
| Signaling by integrins: implications for tumorigenesis | Q57446989 | ||
| P4510 | describes a project that uses | HEK-TERST | Q54882321 |
| HEK-TERST110 | Q54882322 | ||
| HEK-TERV | Q54882323 | ||
| P433 | issue | 7 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | virus | Q808 |
| SV40 | Q734305 | ||
| cell line | Q21014462 | ||
| P304 | page(s) | 2111-2123 | |
| P577 | publication date | 2002-04-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Enumeration of the simian virus 40 early region elements necessary for human cell transformation | |
| P478 | volume | 22 |
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