Topical interleukin 1 receptor antagonist for treatment of dry eye disease: a randomized clinical trial.

scientific article

Topical interleukin 1 receptor antagonist for treatment of dry eye disease: a randomized clinical trial. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1001/JAMAOPHTHALMOL.2013.195
P932PMC publication ID4167802
P698PubMed publication ID23599118

P50authorPedram HamrahQ7159371
Reza DanaQ16206939
Giulio FerrariQ42391130
Ula V JurkunasQ59817045
Mohammad H DastjerdiQ89228119
Debra A SchaumbergQ114406893
Andre OkanoboQ114572926
P2093author name stringFrancisco Amparo
Leila Smaga
P2860cites workInterleukin-1 in the pathogenesis and treatment of inflammatory diseasesQ24606766
Prevalence of dry eye syndrome among US womenQ28196875
Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye.Q30813799
Doxycycline inhibition of interleukin-1 in the corneal epithelium.Q30900518
Prevalence of dry eye disease among US men: estimates from the Physicians' Health StudiesQ33720070
Desiccating stress promotion of Th17 differentiation by ocular surface tissues through a dendritic cell-mediated pathwayQ33938235
Characterization of effector T cells in dry eye diseaseQ34065949
The economic burden of dry eye disease in the United States: a decision tree analysisQ34147677
Corneal epithelial wound healingQ34302886
Phase III safety evaluation of cyclosporine 0.1% ophthalmic emulsion administered twice daily to dry eye disease patients for up to 3 yearsQ34443357
Impact of dry eye syndrome on vision-related quality of lifeQ35741609
Neural basis of sensation in intact and injured corneasQ35755185
Efficacy of topical blockade of interleukin-1 in experimental dry eye diseaseQ36044544
JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cellsQ36380244
Meibomian gland dysfunction: a clinical scheme for description, diagnosis, classification, and grading.Q36639890
IL-17 disrupts corneal barrier following desiccating stress.Q36676135
Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndromeQ36676823
Dry eye disease: an immune-mediated ocular surface disorderQ36916372
Focus on molecules: interleukin-1: a master regulator of the corneal response to injury.Q37401805
The international workshop on meibomian gland dysfunction: executive summaryQ37859542
Interleukin-1beta-induced disruption of barrier function in cultured human corneal epithelial cellsQ39890559
Two multicenter, randomized studies of the efficacy and safety of cyclosporine ophthalmic emulsion in moderate to severe dry eye disease. CsA Phase 3 Study GroupQ41730611
A role of IL-1R1 signaling in the differentiation of Th17 cells and the development of autoimmune diseasesQ41787535
Impaired functional visual acuity of dry eye patientsQ42668504
Estimating the prevalence of dry eye among Indian patients attending a tertiary ophthalmology clinicQ43052456
Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye diseaseQ43723395
Local suppression of IL-1 by receptor antagonist in the rat model of corneal alkali injuryQ44301453
Evaluation of topical cyclosporine for the treatment of dry eye diseaseQ44443222
Amelioration of murine dry eye disease by topical antagonist to chemokine receptor 2.Q45930063
Anion binding and controlled aggregation of human interleukin-1 receptor antagonistQ46104923
Effect of anakinra on functional status in patients with active rheumatoid arthritis receiving concomitant therapy with traditional disease modifying antirheumatic drugs: evidence from the OMEGA Trial.Q46478756
Utility assessment among patients with dry eye disease.Q53379868
Unpreserved carboxymethylcellulose artificial tears evaluated in patients with keratoconjunctivitis siccaQ67574582
Binding sites for human interleukin 1 alpha, gamma interferon and tumor necrosis factor on cultured fibroblasts of normal cornea and keratoconusQ68005187
Expression of collagenolytic/gelatinolytic metalloproteinases by normal corneaQ68479664
Detection of mRNA for the cytokines, interleukin-1 alpha and interleukin-8, in corneas from patients with pseudophakic bullous keratopathyQ72016880
Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis siccaQ72993423
Prevention of allergic eye disease by treatment with IL-1 receptor antagonistQ73152150
Interleukin-1 receptor antagonist therapy and induction of anterior chamber-associated immune deviation-type tolerance after corneal transplantationQ73234836
Reliability and validity of the Ocular Surface Disease IndexQ73801624
Wavefront analysis of higher order aberrations in dry eye patientsQ80182881
The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007)Q80347907
Chronic blockade of interleukin-1 (IL-1) prevents and attenuates neuropathic pain behavior and spontaneous ectopic neuronal activity following nerve injuryQ84963644
P433issue6
P407language of work or nameEnglishQ1860
P921main subjecteye diseaseQ3041498
P304page(s)715-723
P577publication date2013-06-01
P1433published inJAMA OphthalmologyQ4787301
P1476titleTopical interleukin 1 receptor antagonist for treatment of dry eye disease: a randomized clinical trial
P478volume131

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cites work (P2860)
Q64072411A Phase I/II Placebo-Controlled Randomized Pilot Clinical Trial of Recombinant Deoxyribonuclease (DNase) Eye Drops Use in Patients With Dry Eye Disease
Q37417825A randomized controlled trial of omega-3 fatty acids in dry eye syndrome
Q35220614Aberrant interleukin-1 signalling does not increase susceptibility of mice to NOD2-dependent uveitis
Q38460976Advances in pharmacotherapy for allergic conjunctivitis
Q38886086Ageing and ocular surface immunity.
Q59136398Anakinra Therapy for Non-cancer Inflammatory Diseases
Q35863016Anti-inflammatory effects of hinokitiol on human corneal epithelial cells: an in vitro study
Q37278726Bilateral corneal ulceration in ocular graft-versus-host disease
Q35678783Corneal sensitivity following lacrimal gland excision in the rat.
Q27676526Design of a superior cytokine antagonist for topical ophthalmic use
Q37242107Do Cyclosporine A, an IL-1 Receptor Antagonist, Uridine Triphosphate, Rebamipide, and/or Bimatoprost Regulate Human Meibomian Gland Epithelial Cells?
Q36250852Dry Eye Signs and Symptoms Persist During Systemic Neutralization of IL-1β by Canakinumab or IL-17A by Secukinumab
Q34473772Establishing PAX6 as a biomarker to detect early loss of ocular phenotype in human patients with Sjögren's syndrome
Q37359850Evaluation of patients with dry eye disease for conjunctival Chlamydia trachomatis and Ureaplasma urealyticum
Q33748628High Frequency of Latent Conjunctival C. trachomatis, M. hominis, and U. urealyticum Infections in Young Adults with Dry Eye Disease
Q26740643Immunomodulation on the ocular surface: a review
Q50599398Intense pulsed light treatment and meibomian gland expression for moderate to advanced meibomian gland dysfunction.
Q35133812Interleukin-1 as a common denominator from autoinflammatory to autoimmune disorders: premises, perils, and perspectives
Q38197286Macrophages: important players in primary Sjögren's syndrome?
Q34028408Managing Sjögren's Syndrome and non-Sjögren Syndrome dry eye with anti-inflammatory therapy.
Q43075719Neuropathic Corneal Pain: Approaches for Management
Q93341813Ocular Graft-versus-Host Disease after Hematopoietic Cell Transplantation: Expert Review from the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and Transplant Complications Wo
Q38904210Ocular Manifestations of Inherited Phospholipase-Cγ2-Associated Antibody Deficiency and Immune Dysregulation
Q90371647Ocular graft-versus-host disease after hematopoietic cell transplantation: Expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and Transplant Complications Working Party of the EBMT
Q36990254Targeting Imbalance between IL-1β and IL-1 Receptor Antagonist Ameliorates Delayed Epithelium Wound Healing in Diabetic Mouse Corneas
Q52768652The emerging role of interleukin (IL)-1 in the pathogenesis and treatment of inflammatory and degenerative eye diseases.
Q38219053The eye: a window of opportunity in rheumatoid arthritis?
Q90586597The immunoregulatory role of corneal epithelium-derived thrombospondin-1 in dry eye disease
Q47563654The levels of 12 cytokines and growth factors in tears: hyperthyreosis vs euthyreosis.
Q50110517Therapeutic inhibitors for the treatment of dry eye syndrome.
Q47132797Therapies for Meibomian Gland Dysfunction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Q37195776Topical administration of interleukin-1 receptor antagonist as a therapy for aqueous-deficient dry eye in autoimmune disease.
Q37636664Treating inflammation by blocking interleukin-1 in humans
Q26799747Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies
Q38766815Understanding Neuropathic Corneal Pain--Gaps and Current Therapeutic Approaches

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