review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0531-5565(00)00231-X |
P698 | PubMed publication ID | 11295504 |
P2093 | author name string | West M | |
Floyd RA | |||
Hensley K | |||
P2860 | cites work | Crystal structure of the truncated cubic core component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex | Q27764861 |
Aging: a theory based on free radical and radiation chemistry | Q27860549 | ||
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids | Q28138849 | ||
The biologic clock: the mitochondria? | Q28249363 | ||
The retardation of aging by caloric restriction: studies in rodents and primates | Q28301086 | ||
Inactivation of aconitase and oxoglutarate dehydrogenase in skeletal muscle in vitro by superoxide anions and/or nitric oxide | Q28570945 | ||
Causes, effects, and constraints in the genetics of human longevity | Q28768489 | ||
The p66shc adaptor protein controls oxidative stress response and life span in mammals | Q29614553 | ||
Mitochondrial control of cell death | Q29617739 | ||
Oxidative stress, caloric restriction, and aging | Q29618229 | ||
Protein oxidation in aging, disease, and oxidative stress | Q29619442 | ||
Protein modification in aging | Q30403466 | ||
Degradation of oxidized proteins in mammalian cells. | Q30427697 | ||
Neuroinflammatory processes are important in neurodegenerative diseases: an hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development | Q33669393 | ||
Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria | Q33735271 | ||
Antioxidants, oxidative stress, and degenerative neurological disorders | Q33796840 | ||
Measurement of 3-nitrotyrosine and 5-nitro-gamma-tocopherol by high-performance liquid chromatography with electrochemical detection | Q33864171 | ||
Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication | Q33877846 | ||
Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. | Q33914401 | ||
Oxygen poisoning and x-irradiation: a mechanism in common | Q34235248 | ||
High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys | Q70919163 | ||
The spin-trap N-tert-alpha-phenyl-butylnitrone prolongs the life span of the senescence accelerated mouse | Q71840061 | ||
Apoptosis: a two-edged sword in aging | Q73432785 | ||
Apoptosis. Mitochondria--the death signal integrators | Q74257381 | ||
Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle | Q74270238 | ||
A spin trap, N-tert-butyl-alpha-phenylnitrone extends the life span of mice | Q74616935 | ||
Metabolic impairment induces oxidative stress, compromises inflammatory responses, and inactivates a key mitochondrial enzyme in microglia | Q77366399 | ||
Selective inactivation of alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal | Q77648460 | ||
Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria | Q77917891 | ||
Role of free radicals in mutation, cancer, aging, and the maintenance of life | Q79405506 | ||
Protein oxidation and aging | Q34243989 | ||
Oxidative damage and mitochondrial decay in aging | Q34326443 | ||
Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species | Q34338013 | ||
The rate of free radical production as a determinant of the rate of aging: evidence from the comparative approach | Q34468457 | ||
Somatic mutations of the mitochondrial genome in human colorectal tumours | Q34478926 | ||
Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone. | Q34532399 | ||
Mitochondrial DNA sequence variation in human evolution and disease. | Q35744723 | ||
Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase | Q36077271 | ||
Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity | Q36266822 | ||
Action of food restriction in delaying the aging process | Q36303200 | ||
Declines in mitochondrial respiration during cardiac reperfusion: age-dependent inactivation of alpha-ketoglutarate dehydrogenase | Q36378813 | ||
Oxidative damage during aging targets mitochondrial aconitase | Q36588831 | ||
Mitochondrial adenine nucleotide translocase is modified oxidatively during aging | Q36625101 | ||
Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy | Q37311405 | ||
A role of mixed-function oxidation reactions in the accumulation of altered enzyme forms during aging | Q39670223 | ||
Protein oxidation and loss of protease activity may lead to cataract formation in the aged lens | Q39690266 | ||
Selective inactivation of the transacylase components of the 2-oxo acid dehydrogenase multienzyme complexes of Escherichia coli | Q40000315 | ||
Mitochondrial genetics: a paradigm for aging and degenerative diseases? | Q41112226 | ||
Reactive oxygen species, mitochondria, apoptosis and aging. | Q41601406 | ||
Genetics of aging | Q41614200 | ||
Aging and proteolysis of oxidized proteins | Q41660859 | ||
Tricarboxylic acid cycle flux and enzyme activities in the isolated working rat heart | Q42051952 | ||
Comparative resistance of the 20S and 26S proteasome to oxidative stress. | Q42159087 | ||
Low mitochondrial free radical production per unit O2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds. | Q42488705 | ||
Age-related activation of microglia and astrocytes: in vitro studies show persistent phenotypes of aging, increased proliferation, and resistance to down-regulation | Q43478741 | ||
Aging in rodent brain: alteration in astrocyte population | Q47709449 | ||
Biological tyrosine nitration: a pathophysiological function of nitric oxide and reactive oxygen species | Q47774945 | ||
Relationship between enzymatic activity loss and post-translational protein modification in aging | Q47981163 | ||
Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial Alzheimer's disease | Q48163763 | ||
Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site. | Q48340769 | ||
Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. | Q48380256 | ||
Localization at complex I and mechanism of the higher free radical production of brain nonsynaptic mitochondria in the short-lived rat than in the longevous pigeon | Q48398051 | ||
Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction | Q48491092 | ||
ADP-regulation of mitochondrial free radical production is different with complex I- or complex II-linked substrates: implications for the exercise paradox and brain hypermetabolism | Q48686324 | ||
Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of the mouse | Q48934444 | ||
Antioxidant treatment with phenyl-alpha-tert-butyl nitrone (PBN) improves the cognitive performance and survival of aging rats | Q49074614 | ||
Modification of mitochondrial respiration by aging and dietary restriction | Q49160418 | ||
Effect of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone on protein oxidation and life span. | Q52546796 | ||
Reduced Activities of Thiamine-Dependent Enzymes in the Brains and Peripheral Tissues of Patients With Alzheimer's Disease | Q53192901 | ||
Activation of the Cell Death Program by Nitric Oxide Involves Inhibition of the Proteasome | Q58376437 | ||
Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics | Q62472542 | ||
Gene-expression profile of the ageing brain in mice | Q64779230 | ||
An age-dependent release of matrix proteins from rat liver mitochondria | Q67377451 | ||
Increase of plasma IL-6 concentration with age in healthy subjects | Q67595411 | ||
P433 | issue | 4-6 | |
P304 | page(s) | 619-640 | |
P577 | publication date | 2001-04-01 | |
P1433 | published in | Experimental Gerontology | Q15766996 |
P1476 | title | Oxidative biochemical markers; clues to understanding aging in long-lived species | |
P478 | volume | 36 |
Q58648633 | Q58648633 |
Q44126725 | Ageing is reversed, and metabolism is reset to young levels in recovering dauer larvae of C. elegans |
Q35621362 | Ageing, repetitive genomes and DNA damage |
Q37214317 | Aging impairs skeletal muscle mitochondrial bioenergetic function |
Q35801569 | Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production-DNA damage mechanism? |
Q36338129 | An overview of chagasic cardiomyopathy: pathogenic importance of oxidative stress |
Q34031476 | Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3. |
Q44209550 | Cocaine treatment increases expression of a 40 kDa catecholamine-regulated protein in discrete brain regions |
Q44164170 | Comparative mutagenicities of bleomycin and ferric-nitrilotriacetate in lacZ mice. |
Q40078756 | Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes |
Q53287325 | Effects of potential dietary inhibitors of endogenous DNA damage on mutagenesis and lipid peroxidation in lacZ mice. |
Q34835930 | Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein |
Q35857188 | Genome integrity, stem cells and hyaluronan |
Q34310382 | Impact of lifelong sedentary behavior on mitochondrial function of mice skeletal muscle |
Q39318607 | Metabolic Alterations at the Crossroad of Aging and Oncogenesis |
Q38936614 | Metabolic activation of pyrrolizidine alkaloids leading to phototoxicity and photogenotoxicity in human HaCaT keratinocytes. |
Q74394247 | Mitochondrial DNA mutations, oxidative stress, and aging |
Q28388306 | Mitochondrial Metabolism in Aging Heart |
Q35966058 | Mitochondrial dysfunction measured in vivo |
Q33743900 | Modulatory Effects of Decalepis hamiltonii Extract and Its Compounds on the Antioxidant Status of the Aging Rat Brain |
Q46235032 | Neuronal mitochondrial toxicity of malondialdehyde: inhibitory effects on respiratory function and enzyme activities in rat brain mitochondria |
Q46585759 | New anti-RNS and -RCS products for cosmetic treatment |
Q44068708 | Oxidative damage increases with age in a canine model of human brain aging |
Q37253210 | Photoirradiation of retinyl palmitate in ethanol with ultraviolet light--formation of photodecomposition products, reactive oxygen species, and lipid peroxides |
Q34264357 | Phototoxicity and environmental transformation of polycyclic aromatic hydrocarbons (PAHs)-light-induced reactive oxygen species, lipid peroxidation, and DNA damage |
Q38136247 | Phototoxicity of herbal plants and herbal products |
Q37407189 | Prophylaxis with alpha-lipoic acid against lipopolysaccharide-induced brain injury in rats |
Q41885023 | Protective effect of hyaluronate on oxidative DNA damage in WI-38 and A549 cells |
Q44505373 | Pyridoindole antioxidant stobadine protected bovine serum albumin against the hydroxyl radical mediated cross-linking in vitro. |
Q35891551 | Tocopherol (vitamin E) in Alzheimer's disease and other neurodegenerative disorders |
Q46418938 | UVA photoirradiation of anhydroretinol--formation of singlet oxygen and superoxide |
Q53255903 | UVA photoirradiation of benzo[a]pyrene metabolites: induction of cytotoxicity, reactive oxygen species, and lipid peroxidation. |
Q41742028 | Ultrasensitive UPLC-MS/MS method for analysis of etheno-DNA adducts in human white blood cells |
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