Metastasis suppression by adiponectin: LKB1 rises up to the challenge

scientific article

Metastasis suppression by adiponectin: LKB1 rises up to the challenge is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4161/CAM.4.3.11541
P932PMC publication ID2958609
P698PubMed publication ID20418665
P5875ResearchGate publication ID43343061

P2093author name stringDipali Sharma
Neeraj K Saxena
P2860cites workAdiponectin in relation to malignancies: a review of existing basic research and clinical evidenceQ37081272
LKB1; linking cell structure and tumor suppressionQ37333592
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosisQ38361016
Adiponectin mediates an antiproliferative response in human MDA-MB 231 breast cancer cellsQ39936443
Antiproliferative effect of adiponectin on MCF7 breast cancer cells: a potential hormonal link between obesity and cancerQ40182792
Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice.Q40200727
Adiponectin mediates antiproliferative and apoptotic responses in human MCF7 breast cancer cellsQ40283150
Adiponectin inhibits cell proliferation by interacting with several growth factors in an oligomerization-dependent manner.Q40453964
Mature adipocytes, but not preadipocytes, promote the growth of breast carcinoma cells in collagen gel matrix culture through cancer–stromal cell interactionsQ40630211
Capacity of adipose tissue to promote growth and metastasis of a murine mammary carcinoma: Effect of estrogen and progesteroneQ41623563
AdipoQ is a novel adipose-specific gene dysregulated in obesityQ42813232
Preadipocytes stimulate breast cancer cell growthQ42820435
Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilizationQ42835415
Adiponectin and protection against type 2 diabetes mellitusQ44290932
Impaired activation of AMP-kinase and fatty acid oxidation by globular adiponectin in cultured human skeletal muscle of obese type 2 diabeticsQ46381308
Serum adiponectin and leptin levels in Taiwanese breast cancer patients.Q46600194
Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasmaQ71842674
Association of serum adiponectin levels with breast cancer riskQ79342715
LKB1 protein expression in human breast cancerQ79755572
Adiponectin and leptin expression in primary ductal breast cancer and in adjacent healthy epithelial and myoepithelial tissueQ79786571
Low plasma adiponectin levels predict progression of coronary artery calcificationQ81378144
MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasmQ24296287
Cloning of adiponectin receptors that mediate antidiabetic metabolic effectsQ24304889
Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRADQ24305094
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectinQ24564272
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowthQ28211693
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinaseQ28258611
Analysis of the LKB1-STRAD-MO25 complexQ28294900
The adipocyte-secreted protein Acrp30 enhances hepatic insulin actionQ28505765
The tumor suppressor gene LKB1 is associated with prognosis in human breast carcinomaQ28573021
Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndromeQ28586196
A Novel Serum Protein Similar to C1q, Produced Exclusively in AdipocytesQ28590335
Cancer metastasis: building a frameworkQ29616783
Adipose tissue as an endocrine organQ29620407
Demonstration of adiponectin receptors 1 and 2 mRNA expression in human breast cancer cellsQ33264493
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in miceQ34118282
LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cellsQ34155989
Adiponectin and Metabolic SyndromeQ34269072
Adiponectin and breast cancer riskQ34303243
cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1).Q34377772
Adiponectin and cancer: a systematic reviewQ34506490
Molecular links between obesity and breast cancerQ34530905
Adiponectin: a link between obesity and cancerQ34549919
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in miceQ35108391
Breast cancer and obesity: an updateQ35147502
Adiponectin: A novel adipokine linking adipocytes and vascular functionQ35794441
The AMP-activated protein kinase pathway--new players upstream and downstream.Q35930365
New roles for the LKB1-->AMPK pathway.Q36076064
Adipose tissue, adipokines, and inflammationQ36114223
Effects of adiponectin on breast cancer cell growth and signalingQ36614699
Mechanisms of disease: adipokines and breast cancer - endocrine and paracrine mechanisms that connect adiposity and breast cancerQ36766440
Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progressionQ36885845
P433issue3
P304page(s)358-362
P577publication date2010-07-17
P1433published inCell Adhesion and MigrationQ15817193
P1476titleMetastasis suppression by adiponectin: LKB1 rises up to the challenge
P478volume4

Reverse relations

cites work (P2860)
Q38684517ADIPOQ/adiponectin induces cytotoxic autophagy in breast cancer cells through STK11/LKB1-mediated activation of the AMPK-ULK1 axis
Q64945853Adiponectin, Obesity, and Cancer: Clash of the Bigwigs in Health and Disease.
Q92854261Adipose Tissue, Obesity and Adiponectin: Role in Endocrine Cancer Risk
Q26799865Cross-Talk between Adiponectin and IGF-IR in Breast Cancer
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Q64075830Early and late endothelial response in breast cancer metastasis in mice: simultaneous quantification of endothelial biomarkers using a mass spectrometry-based method
Q36849638Evolving role of adiponectin in cancer-controversies and update
Q38217467Gene of the month. AMP kinase (PRKAA1).
Q90392625Glitazone loaded fat enhances adiponectin production and inhibits breast cancer cell proliferation
Q40509533Hypoxia-Induced Upregulation of miR-132 Promotes Schwann Cell Migration After Sciatic Nerve Injury by Targeting PRKAG3.
Q37868986LKB1 signaling in advancing cell differentiation
Q38153628Leptin and adiponectin: emerging therapeutic targets in breast cancer
Q89598674Leptin, Adiponectin, and Sam68 in Bone Metastasis from Breast Cancer
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Q35154969Persistent organic pollutants and obesity: are they potential mechanisms for breast cancer promotion?
Q38597253Signals from the Adipose Microenvironment and the Obesity-Cancer Link-A Systematic Review.

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