Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease

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Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease is …
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scholarly articleQ13442814

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P356DOI10.1016/J.NEUROBIOLAGING.2014.05.019
P932PMC publication ID4170854
P698PubMed publication ID24952994

P50authorKaj BlennowQ28321550
Henrik ZetterbergQ6252048
Ulf AndreassonQ97016159
Cynthia M CarlssonQ114270827
Mark A SagerQ114336826
Carey E. GleasonQ117234552
Hanna M. BlazelQ117234582
Sterling C. JohnsonQ51007286
Michelle M MielkeQ60909929
Luigi PuglielliQ92689767
P2093author name stringSanjay Asthana
Norman J Haughey
Veera V R Bandaru
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Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control studyQ34274231
Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A.Q34317415
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Plasma sphingomyelins are associated with cognitive progression in Alzheimer's diseaseQ35555867
Serum ceramides increase the risk of Alzheimer disease: the Women's Health and Aging Study II.Q36149981
Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathwayQ36321788
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Could plasma sphingolipids be diagnostic or prognostic biomarkers for Alzheimer's disease?Q36768801
Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signalingQ37123974
The liquid-ordered phase in membranesQ37262381
Amyloid-first and neurodegeneration-first profiles characterize incident amyloid PET positivityQ37291586
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Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblastsQ41922039
Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acidQ42474499
Middle-aged children of persons with Alzheimer's disease: APOE genotypes and cognitive function in the Wisconsin Registry for Alzheimer's PreventionQ42673976
Ceramide stabilizes beta-site amyloid precursor protein-cleaving enzyme 1 and promotes amyloid beta-peptide biogenesisQ44370232
Perturbation of sphingolipid metabolism and ceramide production in HIV-dementiaQ44750872
Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitroQ46663698
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Alzheimer peptides perturb lipid-regulating enzymesQ46873173
Ceramide activates heterotrimeric protein phosphatase 2A.Q48246807
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Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicityQ49155965
Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology.Q51576488
Molecular recognition of a single sphingolipid species by a protein's transmembrane domain.Q51762180
Automatic detection vs controlled search: a paper-and-pencil approach.Q52262016
Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.Q53270598
Sphingomyelin suppresses the binding and utilization of low density lipoproteins by skin fibroblastsQ71160092
Protein Phosphatase 2A Is the Major Enzyme in Brain that Dephosphorylates τ Protein Phosphorylated by Proline‐Directed Protein Kinases or Cyclic AMP‐Dependent Protein KinaseQ71832645
P433issue11
P921main subjectcerebrospinal fluidQ54196
Alzheimer's diseaseQ11081
sphingolipidsQ410395
P304page(s)2486-2494
P577publication date2014-05-27
P1433published inNeurobiology of AgingQ7002141
P1476titleCerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease
P478volume35

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cites work (P2860)
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