Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands

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Control of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1359-6101(00)00030-7
P698PubMed publication ID11312114

P2093author name stringWilson K
Horowitz MC
Xi Y
Kacena MA
P2860cites workThe receptor for the cytotoxic ligand TRAILQ24310481
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activationQ24311588
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cellsQ24315251
Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cellsQ24321566
Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesisQ24324701
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell functionQ24336057
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligandQ24653311
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motifQ28138697
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient miceQ28140546
Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysisQ28141482
Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survivalQ28142897
Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complexQ28145172
Genetic linkage of familial expansile osteolysis to chromosome 18qQ28237649
Osf2/Cbfa1: a transcriptional activator of osteoblast differentiationQ28240596
An antagonist decoy receptor and a death domain-containing receptor for TRAILQ28245153
Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinaseQ28278061
The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptorQ28285539
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesisQ28293009
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signalingQ28513445
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and deathQ28609905
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblastsQ29547605
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligandQ29619331
Mesenchymal stem cellsQ29619804
Characterization of structural domains of human osteoclastogenesis inhibitory factorQ34457751
Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitroQ34459310
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.Q34469691
Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infectionQ35008871
Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repressionQ35169193
Modulation of osteoclast differentiationQ35957509
Regulation of peripheral lymph node genesis by the tumor necrosis factor family member TRANCEQ36368551
Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptorsQ36375584
Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgeneQ37265676
Estrogen deficiency induces bone loss by enhancing T-cell production of TNF-alphaQ37271202
Regulation of osteoprotegerin mRNA levels by prostaglandin E2 in human bone marrow stroma cellsQ38336153
Cytokines and estrogen in bone: anti-osteoporotic effectsQ40900427
Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosisQ40926683
Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cellsQ40927574
Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokinesQ41000781
Transforming growth factor-beta stimulates the production of osteoprotegerin/osteoclastogenesis inhibitory factor by bone marrow stromal cellsQ41004339
Osteoprotegerin mRNA is increased by interleukin-1 alpha in the human osteosarcoma cell line MG-63 and in human osteoblast-like cellsQ41016610
Tumor necrosis factor-alpha and -beta upregulate the levels of osteoprotegerin mRNA in human osteosarcoma MG-63 cellsQ41016675
TR1, a new member of the tumor necrosis factor receptor superfamily, induces fibroblast proliferation and inhibits osteoclastogenesis and bone resorptionQ41027241
Regulation of osteoclast functionQ41486748
Osteoblastic gene expression during adipogenesis in hematopoietic supporting murine bone marrow stromal cellsQ41575889
Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formationQ42475736
The cell-surface form of colony-stimulating factor-1 is regulated by osteotropic agents and supports formation of multinucleated osteoclast-like cells.Q42831612
Macrophage colony stimulating factor restores in vivo bone resorption in the op/op osteopetrotic mouseQ43681246
Lipid oxidation products have opposite effects on calcifying vascular cell and bone cell differentiation. A possible explanation for the paradox of arterial calcification in osteoporotic patients.Q45946808
cAMP stimulates osteoblast-like differentiation of calcifying vascular cells. Potential signaling pathway for vascular calcification.Q45996887
Osteoblastic cells are involved in osteoclast formation.Q54374668
Promoter structure of mouse RANKL/TRANCE/OPGL/ODF geneQ58008649
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γQ59064307
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
Osteoprotegerin mRNA is expressed in primary human osteoblast-like cells: down-regulation by glucocorticoidsQ61480394
The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cellsQ69541163
Osteoprotegerin blocks bone cancer-induced skeletal destruction, skeletal pain and pain-related neurochemical reorganization of the spinal cordQ73766127
Osteoclastogenesis inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclastQ77350563
Osteotropic agents regulate the expression of osteoclast differentiation factor and osteoprotegerin in osteoblastic stromal cellsQ77484251
Potential role of cbfa1, an essential transcriptional factor for osteoblast differentiation, in osteoclastogenesis: regulation of mRNA expression of osteoclast differentiation factor (ODF)Q77630526
Transforming growth factor-beta1 increases mRNA levels of osteoclastogenesis inhibitory factor in osteoblastic/stromal cells and inhibits the survival of murine osteoclast-like cellsQ77630549
P433issue1
P921main subjectTNFQ18032037
P304page(s)9-18
P577publication date2001-03-01
P1433published inCytokine and Growth Factor ReviewsQ15763303
P1476titleControl of osteoclastogenesis and bone resorption by members of the TNF family of receptors and ligands
P478volume12

Reverse relations

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