Initial evidence that GLP-1 receptor blockade fails to suppress postprandial satiety or promote food intake in humans

scientific article

Initial evidence that GLP-1 receptor blockade fails to suppress postprandial satiety or promote food intake in humans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.APPET.2014.07.009
P932PMC publication ID4171349
P698PubMed publication ID25049134

P50authorSusan J MelhornQ96249055
P2093author name stringChristian L Roth
Ellen A Schur
Vidhi Tyagi
Anne Smeraglio
P2860cites workGastrointestinal satiety signals in humans--physiologic roles for GLP-1 and PYY?Q28250913
The anorectic effect of GLP-1 in rats is nutrient dependentQ28484398
Exendin-4 increases blood glucose levels acutely in rats by activation of the sympathetic nervous systemQ33840311
Glucagon-like peptide-1 receptor knockout mice are protected from high-fat diet-induced insulin resistanceQ34157515
No difference in satiety or in subsequent energy intakes between a beverage and a solid foodQ34343143
The biology of incretin hormonesQ34499706
Glucagon-like peptide-1: a potent regulator of food intake in humansQ35565562
The gut hormones PYY 3-36 and GLP-1 7-36 amide reduce food intake and modulate brain activity in appetite centers in humansQ35700651
Glucagon-like peptide 1: evolution of an incretin into a treatment for diabetesQ35772029
GLP-1 receptor antagonist exendin-(9-39) elevates fasting blood glucose levels in congenital hyperinsulinism owing to inactivating mutations in the ATP-sensitive K+ channelQ36249759
Regulation of islet hormone release and gastric emptying by endogenous glucagon-like peptide 1 after glucose ingestionQ37061286
Acute peripheral GLP-1 receptor agonism or antagonism does not alter energy expenditure in rats after Roux-en-Y gastric bypassQ37100802
Exaggerated glucagon-like peptide 1 response is important for improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes.Q37110621
Evidence that intestinal glucagon-like peptide-1 plays a physiological role in satiety.Q37136936
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humansQ37377728
Exendin(9-39)amide is an antagonist of glucagon-like peptide-1(7-36)amide in humansQ39801749
A simplified, colorimetric micromethod for xylose in serum or urine, with phloroglucinolQ41675896
Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive mannerQ42134405
Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteersQ43638669
The effect of acute hyperglycaemia on appetite and food intake in Type 1 diabetes mellitusQ43770070
GLP-1 as a satiety factor in children with eating disordersQ43969390
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitusQ44467072
Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats.Q45271809
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetesQ46458868
Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in ratsQ47283044
GLP-1 antagonism with exendin (9-39) fails to increase spontaneous meal size in ratsQ47442436
Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2.Q48218648
D-glucose suppression of eating after intra-third ventricle infusion in rat.Q48398206
A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humansQ48664995
Time course of effects of preloads high in fat or carbohydrate on food intake and hunger ratings in humansQ48873625
Effect of glucagon-like peptide-1 receptor antagonism on appetite and food intake in healthy men.Q53039133
The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesityQ58448710
Limitations of indirect methods of estimating small bowel transit in manQ70344615
Lipase inhibition and hormonal status, body composition and gastrointestinal processing of a liquid high-fat mixed meal in moderately obese subjectsQ71128936
Reproducibility, power and validity of visual analogue scales in assessment of appetite sensations in single test meal studiesQ73510748
Stimulation of the small intestine by nutrients in relation to phase of the migrating motor complexQ73927840
Effects of glucagon on postprandial carbohydrate metabolism in nondiabetic humansQ74081998
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety--effect of obesity and weight reductionQ74287135
Effects of hyperglycemia and hyperinsulinemia on satiety in humansQ74310151
Glucagon-like peptide 1 has a physiological role in the control of postprandial glucose in humans: studies with the antagonist exendin 9-39Q77804907
Effects of a preload on reduction of food intake by GLP-1 in healthy subjectsQ79394103
P921main subjectsatietyQ1562684
P304page(s)85-90
P577publication date2014-07-15
P1433published inAppetiteQ13430275
P1476titleInitial evidence that GLP-1 receptor blockade fails to suppress postprandial satiety or promote food intake in humans
P478volume82

Reverse relations

cites work (P2860)
Q36240979Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes
Q39047697Ghrelin, CCK, GLP-1, and PYY(3-36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB.
Q42936904Glucagon-like peptide-1 receptors in the brain: controlling food intake and body weight
Q33838133Gut hormones such as amylin and GLP-1 in the control of eating and energy expenditure
Q38575560Intestinal GLP-1 and satiation: from man to rodents and back
Q53589377Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery.

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