Pharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review

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Pharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review is …
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review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1041373421
P356DOI10.2165/00003088-200140030-00004
P698PubMed publication ID11327198

P2093author name stringCutler NR
Crawford AW
Jhee SS
Shiovitz T
P2860cites workPotential drug interactions with the novel antimigraine compound zolmitriptan (Zomig, 311C90)Q28256565
Headache recurrence after subcutaneous sumatriptan and early treatmentQ28327716
Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptorsQ28373188
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Sumatriptan nasal spray in the acute treatment of migraine: a review of clinical studiesQ33792830
Cardiovascular safety of 5HT1B/1D agonists--is there a cause for concern?Q34481198
The pharmacokinetics and effects on blood pressure of multiple doses of the novel anti-migraine drug zolmitriptan (311C90) in healthy volunteersQ34738942
The absolute bioavailability and metabolic disposition of the novel antimigraine compound zolmitriptan (311C90).Q34741307
Selective 5-HT1D alpha serotonin receptor gene expression in trigeminal ganglia: implications for antimigraine drug developmentQ35189866
The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteersQ35802614
Pharmacokinetics and tolerability of oral rizatriptan in healthy male and female volunteersQ36053366
The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteersQ36053563
The interaction between propranolol and the novel antimigraine agent zolmitriptan (311C90)Q36094218
Mode of action of the anti-migraine drug sumatriptanQ36465525
Joint 1994 Wolff Award Presentation. Peripheral and central trigeminovascular activation in cat is blocked by the serotonin (5HT)-1D receptor agonist 311C90.Q36723711
The efficacy of subcutaneous sumatriptan in the treatment of recurrence of migraine headacheQ36905403
Pharmacokinetics of rizatriptan tablets during and between migraine attacksQ39372579
Oral almotriptan vs. oral sumatriptan in the abortive treatment of migraine: a double-blind, randomized, parallel-group, optimum-dose comparisonQ39417816
Oral rizatriptan versus oral sumatriptan: a direct comparative study in the acute treatment of migraine. Rizatriptan 030 Study GroupQ39420231
Crossover comparison of rizatriptan 5 mg and 10 mg versus sumatriptan 25 mg and 50 mg in migraine. Rizatriptan Protocol 046 Study GroupQ39420238
A comparative trial of zolmitriptan and sumatriptan for the acute oral treatment of migraineQ39431252
Patient preference for oral sumatriptan 25 mg, 50 mg, or 100 mg in the acute treatment of migraine: a double-blind, randomized, crossover study. Sumatriptan Tablets S2CM11 Study Group.Q39432404
Comparison of rizatriptan 10 mg vs. naratriptan 2.5 mg in migraineQ39435550
Early clinical experience with subcutaneous naratriptan in the acute treatment of migraine: a dose-ranging studyQ39439890
Efficacy and adverse events of subcutaneous, oral, and intranasal sumatriptan used for migraine treatment: a systematic review based on number needed to treatQ39443442
Tolerability and efficacy of naratriptan tablets with long-term treatment (6 months). Naratriptan Long-term Study GroupQ39447979
Rizatriptan (MAXALT) for the acute treatment of migraine and migraine recurrence. A placebo-controlled, outpatient study. Rizatriptan 022 Study GroupQ39448143
Efficacy and safety of sumatriptan tablets (25 mg, 50 mg, and 100 mg) in the acute treatment of migraine: defining the optimum doses of oral sumatriptanQ39448906
Naratriptan is effective and well tolerated in the acute treatment of migraine. Results of a double-blind, placebo-controlled, parallel-group study. Naratriptan S2WA3001 Study GroupQ39451379
Naratriptan is effective and well tolerated in the acute treatment of migraine. Results of a double-blind, placebo-controlled, crossover study. The Naratriptan S2WA3003 Study GroupQ39451910
Sumatriptan nasal spray for the acute treatment of migraine. Results of two clinical studiesQ39452003
Optimizing the dose of zolmitriptan (Zomig, 311C90) for the acute treatment of migraine. A multicenter, double-blind, placebo-controlled, dose range-finding study. The 017 Clinical Trial Study GroupQ39452008
Rizatriptan vs sumatriptan in the acute treatment of migraine. A placebo-controlled, dose-ranging study. Dutch/US Rizatriptan Study GroupQ39461354
Oral sumatriptan in the acute treatment of migraine and migraine recurrence in general practiceQ39463122
A comparison of subcutaneous sumatriptan and dihydroergotamine nasal spray in the acute treatment of migraineQ39463497
Migraine and cluster headache--their management with sumatriptan: a critical review of the current clinical experienceQ39471681
The safety of concomitant use of sumatriptan and antidepressant treatmentsQ39475958
Sumatriptan clinical pharmacokineticsQ40589845
Serotonin (5-HT) and migraineQ40633746
Clinical and experimental effects of sumatriptan in humansQ40855384
Side effects of ergotamineQ41126543
Chest symptoms after sumatriptan: a two-year clinical practice review in 735 consecutive migraine patientsQ41289268
Sumatriptan contraindications and the serotonin syndrome.Q41707189
Lack of an interaction between propranolol and sumatriptanQ42129047
Naratriptan: biological profile in animal models relevant to migraineQ42549327
Permeation of sumatriptan through human vaginal and buccal mucosaQ46652580
Effects of the novel high-affinity 5-HT(1B/1D)-receptor ligand frovatriptan in human isolated basilar and coronary arteriesQ47698318
Migraine polypharmacy and the tolerability of sumatriptan: a large-scale, prospective studyQ48089043
Inhibition of trigeminal neurons by intravenous administration of the serotonin (5HT)1B/D receptor agonist zolmitriptan (311C90): are brain stem sites therapeutic target in migraine?Q48896233
Pharmacokinetics and pharmacodynamics of zolmitriptan in patients with mild to moderate hypertension: a double-blind, placebo-controlled study.Q50868159
The pharmacodynamics and pharmacokinetics of the 5HT1B/1D-agonist zolmitriptan in healthy young and elderly men and women.Q50896559
No need to adjust the dose of 311C90 (zolmitriptan), a novel anti-migraine treatment, in patients with renal failure not requiring dialysis.Q50918652
Eletriptan in acute migraine: a double-blind, placebo-controlled comparison to sumatriptan. Eletriptan Steering Committee.Q53339904
Effect of subcutaneous naratriptan on forearm blood flow.Q53350815
Effect of hepatic impairment on the pharmacokinetics of zolmitriptan.Q53946789
The clinical pharmacokinetics of zolmitriptan.Q54394241
Comparison of the Efficacy of Zolmitriptan and Sumatriptan: Issues in Migraine Trial DesignQ57024741
Oral sumatriptan in acute migraineQ58619528
Treatment of migraine attacks with sumatriptan. The Subcutaneous Sumatriptan International Study GroupQ68241898
The Clinical Pharmacology, Pharmacokinetics and Metabolism of SumatriptanQ68252114
Sumatriptan--an oral dose-defining study. The Oral Sumatriptan Dose-Defining Study GroupQ68252118
Evaluation of a multiple-dose regimen of oral sumatriptan for the acute treatment of migraine. The Oral Sumatriptan International Multiple-Dose Study GroupQ68252122
Cephalic hyperemia during migraine headaches. A prospective studyQ69642768
How does sumatriptan perform in clinical practice?Q71372255
Distribution and excretion of sumatriptan in human milkQ71675382
Pharmacokinetics and food interaction of MK-462 in healthy malesQ71964042
Oral sumatriptan in preventing headache recurrence after treatment of migraine attacks with subcutaneous sumatriptanQ71980834
Lack of Pharmacokinetic Interaction Between Butorphanol Tartrate Nasal Spray and Sumatriptan SuccinateQ71997318
Single dose pharmacokinetics of sumatriptan in healthy volunteersQ72281602
Characterization of the enzyme responsible for the metabolism of sumatriptan in human liverQ72371152
Disposition and pharmacokinetics of the antimigraine drug, rizatriptan, in humansQ73302256
Lack of pharmacokinetic interaction between sumatriptan and naproxenQ73345826
Eletriptan and coronary arteryQ73604680
Pharmacokinetic interaction between verapamil and almotriptan in healthy volunteersQ73820770
Clinical efficacy and tolerability of 2.5 mg zolmitriptan for the acute treatment of migraine. The 042 Clinical Trial Study GroupQ73884479
A placebo-controlled crossover study of rizatriptan in the treatment of multiple migraine attacks. Rizatriptan Multiple Attack Study GroupQ77332487
Effects of subcutaneous naratriptan on systemic and pulmonary haemodynamics and coronary artery diameter in humansQ78020306
Determination of the human cytochrome P450 isoforms involved in the metabolism of zolmitriptanQ93927625
P433issue3
P921main subjectpharmacokineticsQ323936
pharmacodynamicsQ725307
P304page(s)189-205
P577publication date2001-01-01
P1433published inClinical PharmacokineticsQ5133788
P1476titlePharmacokinetics and pharmacodynamics of the triptan antimigraine agents: a comparative review
P478volume40

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cites work (P2860)
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