Adipose-tissue and intestinal inflammation - visceral obesity and creeping fat

scientific article

Adipose-tissue and intestinal inflammation - visceral obesity and creeping fat is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3389/FIMMU.2014.00462
P932PMC publication ID4174117
P698PubMed publication ID25309544
P5875ResearchGate publication ID266947569

P50authorBritta SiegmundQ52911890
P2093author name stringLea I Kredel
P2860cites workHigh-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouseQ21136177
Inflammation and insulin resistanceQ22241893
Dietary Intake and Risk of Developing Inflammatory Bowel Disease: A Systematic Review of the LiteratureQ22251115
Obesity: Genetic, molecular, and environmental aspectsQ22252954
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistanceQ24617743
Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasisQ24629044
Role of a critical visceral adipose tissue threshold (CVATT) in metabolic syndrome: implications for controlling dietary carbohydrates: a reviewQ24801508
The origin and definition of brite versus white and classical brown adipocytesQ27013733
Adipose-derived stromal/stem cells: a primerQ27021721
Obesity is associated with macrophage accumulation in adipose tissueQ27860976
Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart StudyQ28219755
ObesityQ28275029
Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese miceQ28730963
Obesity induces a phenotypic switch in adipose tissue macrophage polarizationQ29547686
Macrophages, inflammation, and insulin resistanceQ29614351
Macrophage activation and polarizationQ29616353
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parametersQ29617381
Innate lymphoid cells--a proposal for uniform nomenclatureQ29617431
Inflammatory mechanisms in obesityQ29617932
National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participantsQ29619930
Monocytes and macrophages: developmental pathways and tissue homeostasisQ38214042
Increased intestinal permeability in obese mice: new evidence in the pathogenesis of nonalcoholic steatohepatitisQ38308819
Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight lossQ38323163
A survey of genes differentially expressed in subcutaneous and visceral adipose tissue in men.Q38337189
CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in miceQ39003107
Profiling adipocytokine secretion from creeping fat in Crohn's diseaseQ40316140
The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolyticQ40597320
Inflamed fat: what starts the fire?Q40899161
Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammationQ41838863
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.Q41912120
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cellsQ42183814
Obesity and IBD: are we tipping the scales toward an epidemic?Q42257916
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production.Q42514705
Mesenteric adipose tissue alterations resulting from experimental reactivated colitisQ42515062
Toll-like receptor ligands cause proinflammatory and prodiabetic activation of adipocytes via phosphorylation of extracellular signal-regulated kinase and c-Jun N-terminal kinase but not interferon regulatory factor-3.Q42829836
Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight lossQ43259519
Adiponectin downregulates galectin-3 whose cellular form is elevated whereas its soluble form is reduced in type 2 diabetic monocytesQ43264211
Obesity has minimal impact on clinical outcomes in children with inflammatory bowel diseaseQ43962815
Body weight, gender and response to TNF-α blockers in axial spondyloarthritisQ44115144
Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazoneQ44238663
Adipokines from local fat cells shape the macrophage compartment of the creeping fat in Crohn's diseaseQ44652242
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humansQ44730563
Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease.Q44784148
Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): implication of macrophages resident in the AT.Q45238657
Shades of grey--the blurring view of innate and adaptive immunityQ45333657
Severe and morbid obesity in Crohn's disease patients: prevalence and disease associations.Q45808148
Methotrexate is effective in reactivated colitis and reduces inflammatory alterations in mesenteric adipose tissue during intestinal inflammation.Q46007130
Does weight-adjusted anti-tumour necrosis factor treatment favour obese patients with Crohn's disease?Q46379767
Eosinophils in fat: pink is the new brownQ46615563
Inflammation correlates with markers of T-cell subsets including regulatory T cells in adipose tissue from obese patientsQ46981453
Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parametersQ46988914
Relationship between adipocyte size and adipokine expression and secretionQ47310274
Weight loss regulates inflammation-related genes in white adipose tissue of obese subjectsQ47402001
Unexpected trafficking of immune cells within the adipose tissue during the onset of obesityQ47861318
Increased body mass index is associated with earlier time to loss of response to infliximab in patients with inflammatory bowel diseaseQ47990338
Group 2 innate lymphoid cells show up in the skin.Q50898097
Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity.Q51497448
Interplay between human adipocytes and T lymphocytes in obesity: CCL20 as an adipochemokine and T lymphocytes as lipogenic modulators.Q51891435
Mesenteric fat - control site for bacterial translocation in colitis?Q52888386
CCR2 modulates inflammatory and metabolic effects of high-fat feedingQ29622869
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humansQ29622900
Adipose tissue macrophages promote myelopoiesis and monocytosis in obesityQ33724394
Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbersQ33813607
Release of inflammatory mediators by human adipose tissue is enhanced in obesity and primarily by the nonfat cells: a reviewQ33870787
Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesityQ33930230
Human uterine NK cells interact with uterine macrophages via NKG2D upon stimulation with PAMPsQ33985305
Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob miceQ34006674
Subcutaneous and visceral adipose tissue: their relation to the metabolic syndromeQ34116177
Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophagesQ34150591
Development and function of invariant natural killer T cells producing T(h)2- and T(h)17-cytokinesQ34162198
Invariant natural killer T cells: an innate activation scheme linked to diverse effector functionsQ34323476
Adipose tissue and the immune systemQ34425206
Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation.Q34426034
Role of adipose tissue as an inflammatory organ in human diseasesQ34523574
Evidence for a role of developmental genes in the origin of obesity and body fat distributionQ34597959
Notch signaling pathway activation in normal and hyperglycemic rats differs in the stem cells of visceral and subcutaneous adipose tissueQ34712757
High fat diet accelerates pathogenesis of murine Crohn's disease-like ileitis independently of obesityQ34971829
Normalization of obesity-associated insulin resistance through immunotherapyQ34994222
Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel diseaseQ35001872
Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel diseaseQ35048180
Inflammatory cytokine gene expression in mesenteric adipose tissue during acute experimental colitisQ35080569
Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammationQ35083309
Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissueQ35147250
Inflammatory concepts of obesityQ35151595
Mesenteric fat as a source of C reactive protein and as a target for bacterial translocation in Crohn's diseaseQ35593129
Activation of natural killer T cells promotes M2 Macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesityQ35922180
Adipose tissue and inflammatory bowel disease pathogenesisQ36030894
CCR5 plays a critical role in obesity-induced adipose tissue inflammation and insulin resistance by regulating both macrophage recruitment and M1/M2 statusQ36047622
Macrophage-mediated inflammation in metabolic diseaseQ36060408
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- miceQ36087089
Short term high fat diet challenge promotes alternative macrophage polarization in adipose tissue via natural killer T cells and interleukin-4.Q36097975
Natural killer T cells in adipose tissue prevent insulin resistanceQ36190718
Human fat cell lipolysis: biochemistry, regulation and clinical roleQ36324036
Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastaseQ36377312
Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease.Q52938162
Local proliferation of macrophages in adipose tissue during obesity-induced inflammation.Q53078046
Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.Q53556065
Modifications of mesenteric adipose tissue during moderate experimental colitis in mice.Q54236253
Visceral adipocytes: old actors in obesity and new protagonists in Crohn's disease?Q54348276
Is Crohn's creeping fat an adipose tissue?Q54416901
Orchestration of macrophage polarizationQ56942610
Body fat distribution and insulin resistanceQ60533965
Fat-wrapping in Crohn's disease: pathological basis and relevance to surgical practiceQ67573165
Differences in mRNA expression of the proteins secreted by the adipocytes in human subcutaneous and visceral adipose tissuesQ73189940
TNFalpha release by the nonfat cells of human adipose tissueQ75447940
Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin IIQ77549336
Crohn's disease clinical course and severity in obese patientsQ77742629
T-cell accumulation and regulated on activation, normal T cell expressed and secreted upregulation in adipose tissue in obesityQ79765934
Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depotsQ80596917
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistanceQ81108550
The impact of increased body mass index on the clinical course of Crohn's diseaseQ83157629
Is obesity a risk factor for Crohn's disease?Q83164329
The obese healthy paradox: is inflammation the answer?Q84350474
Does obesity complicate inflammatory bowel diseases?Q84456243
Expression of CD4+ forkhead box P3 (FOXP3)+ regulatory T cells in inflammatory bowel diseaseQ84595874
Comparison of cell proliferation and epigenetic modification of gene expression patterns in canine foetal fibroblasts and adipose tissue-derived mesenchymal stem cellsQ84878398
Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states.Q36402697
Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complicationsQ36546700
Consensus conference statement bariatric surgery for morbid obesity: health implications for patients, health professionals, and third-party payersQ36573719
Mesenteric fat in Crohn's disease: a pathogenetic hallmark or an innocent bystander?Q36587155
Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophagesQ36694157
Adipose tissue macrophages.Q36918994
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypesQ36975445
Relation of abdominal fat depots to systemic markers of inflammation in type 2 diabetesQ37163809
Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production.Q37191048
Adipose tissue NK cells manifest an activated phenotype in human obesityQ37258197
Differences in visceral fat and fat bacterial colonization between ulcerative colitis and Crohn's disease. An in vivo and in vitro studyQ37269026
Blood spotlight on leukocytes and obesity.Q37291602
Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice.Q37358129
Obesity, inflammation, and atherosclerosisQ37462172
Adipokine signaling in inflammatory bowel diseaseQ37466469
Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feedingQ37495662
Developmental plasticity of Th17 and Treg cells.Q37518502
Foxp3+ regulatory T cells: differentiation, specification, subphenotypesQ37523266
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognitionQ37544531
Subcutaneous and visceral adipose tissue: structural and functional differencesQ37572907
What we talk about when we talk about fat.Q37601812
Human adipose tissue macrophages are enhanced but changed to an anti-inflammatory profile in obesity.Q37704756
Defining macrophage phenotype and function in adipose tissueQ37880478
Tissular T(regs): a unique population of adipose-tissue-resident Foxp3+CD4+ T cells that impacts organismal metabolismQ37897011
The impact of obesity on outcomes following major surgery for Crohn's disease: an American College of Surgeons National Surgical Quality Improvement Program assessmentQ37953988
Visceral fat and gut inflammationQ37972334
Adipose tissue-resident immune cells: key players in immunometabolism.Q38026316
Innate lymphoid cells--how did we miss them?Q38071916
Hypoxia and adipose tissue function and dysfunction in obesity.Q38072900
Th1- and Th2-like subsets of innate lymphoid cellsQ38081172
The GH/IGF-1 axis in obesity: pathophysiology and therapeutic considerationsQ38097351
Innate and adaptive immunity in inflammatory bowel disease.Q38115075
White, brown and pink adipocytes: the extraordinary plasticity of the adipose organQ38182351
Adipose tissue-resident regulatory T cells: phenotypic specialization, functions and therapeutic potentialQ38183920
Distinction of white, beige and brown adipocytes derived from mesenchymal stem cellsQ38190952
Adipose invariant natural killer T cells.Q38199760
P921main subjectobesityQ12174
P304page(s)462
P577publication date2014-09-24
P1433published inFrontiers in ImmunologyQ27723748
P1476titleAdipose-tissue and intestinal inflammation - visceral obesity and creeping fat
P478volume5

Reverse relations

cites work (P2860)
Q92447007Adipocyte Specific HO-1 Gene Therapy is Effective in Antioxidant Treatment of Insulin Resistance and Vascular Function in an Obese Mice Model
Q58122569Adipokines and Their Role in Intestinal Inflammation
Q41107429Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice
Q50103146Anatomical, Physiological, and Functional Diversity of Adipose Tissue.
Q42370720Are adipocytokines inflammatory or metabolic mediators in patients with inflammatory bowel disease?
Q36676379Body Composition Changes After Initiation of Raltegravir or Protease Inhibitors: ACTG A5260s
Q59340042Changes in Waist Circumference in HIV-Infected Individuals Initiating a Raltegravir or Protease Inhibitor Regimen: Effects of Sex and Race
Q42376230Crohn's Disease Disturbs the Immune Properties of Human Adipose-Derived Stem Cells Related to Inflammasome Activation.
Q46617053Effects of Food Additives on Immune Cells As Contributors to Body Weight Gain and Immune-Mediated Metabolic Dysregulation
Q42121075Exogenous citrate impairs glucose tolerance and promotes visceral adipose tissue inflammation in mice
Q36840159High-Fat Diet-Induced Obesity Enhances Allograft Rejection
Q37054133Increased Gustatory Response Score in Obesity and Association Levels with IL-6 and Leptin
Q30378828Inflammatory insults and mental health consequences: does timing matter when it comes to depression?
Q46256007Intestinal Ralstonia pickettii augments glucose intolerance in obesity
Q91854278Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease
Q92051810Mechanisms Underlying Bone Loss Associated with Gut Inflammation
Q49966077Obesity and Pancreatic Cancer: Overview of Epidemiology and Potential Prevention by Weight Loss
Q30239737Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes
Q93075393Pathogenesis of fibrostenosing Crohn's disease
Q47272488Postoperative excessive gain in visceral adipose tissue as well as body mass index are associated with adverse outcomes of an ileal pouch
Q36862870Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer
Q33588974The effects of Spirulina Platensis on anthropometric indices, appetite, lipid profile and serum vascular endothelial growth factor (VEGF) in obese individuals: a randomized double blinded placebo controlled trial
Q28121155The mesentery: structure, function, and role in disease
Q36305141The utility of apoptosis inhibitor of macrophages as a possible diagnostic marker in patients with Crohn's disease

Search more.