CD8+ lymphocyte intratumoral infiltration as a stage-independent predictor of Merkel cell carcinoma survival: a population-based study.

scientific article

CD8+ lymphocyte intratumoral infiltration as a stage-independent predictor of Merkel cell carcinoma survival: a population-based study. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1309/AJCPIKDZM39CRPNC
P932PMC publication ID4174450
P698PubMed publication ID25239411

P50authorKelly G PaulsonQ40526856
P2093author name stringJayasri G Iyer
Paul Nghiem
E Margaret Warton
Maryam M Asgari
Miranda Schmidt
Astrid Blom
William T Simonson
Monica Sokil
Stephanie Pietromonaco
Renee M Thibodeau
P2860cites workClonal integration of a polyomavirus in human Merkel cell carcinomaQ24657675
Type, density, and location of immune cells within human colorectal tumors predict clinical outcomeQ28131662
Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigensQ33966574
Effector memory T cells, early metastasis, and survival in colorectal cancerQ33992461
Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging systemQ34208807
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancerQ34210036
Antibodies to Merkel Cell Polyomavirus T Antigen Oncoproteins Reflect Tumor Burden in Merkel Cell Carcinoma PatientsQ34267871
Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature reviewQ34551974
Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancerQ34681333
Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.Q34866209
Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors.Q34985137
Markers of T cell infiltration and function associate with favorable outcome in vascularized high-grade serous ovarian carcinoma.Q35077586
Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.Q35510910
Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.Q36585604
Merkel cell carcinoma: histologic features and prognosisQ37271863
Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancerQ37323046
Prognostic and predictive impact of intra- and peritumoral immune infiltratesQ37918676
Merkel's cell carcinoma in organ recipients: report of 41 casesQ41710517
The immune score as a new possible approach for the classification of cancerQ42539190
Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based studyQ44461515
The prognostic role of tumor-infiltrating CD4 and CD8 T lymphocytes in breast cancer.Q45930148
Presence of tumor-infiltrating lymphocytes is an independent prognostic factor in type I and II endometrial cancerQ47894638
Histopathologic-based prognostic factors of colorectal cancers are associated with the state of the local immune reaction.Q51023201
Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.Q52907227
Prognostic significance of activated CD8(+) T cell infiltrations within esophageal carcinomas.Q52964416
Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection.Q53332082
Merkel cell carcinoma and HIV infection.Q55035696
Tumor Infiltrating Immune Cells and Outcome of Merkel Cell Carcinoma: A Population-Based StudyQ62268141
Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapyQ84776409
Circulating levels of transforming growth factor-βeta (TGF-β) and chemokine (C-X-C motif) ligand-1 (CXCL1) as predictors of distant seeding of circulating tumor cells in patients with metastatic breast cancerQ95527490
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectMerkel cell carcinomaQ1711744
P304page(s)452-458
P577publication date2014-10-01
P1433published inAmerican Journal of Clinical PathologyQ15750224
P1476titleCD8+ lymphocyte intratumoral infiltration as a stage-independent predictor of Merkel cell carcinoma survival: a population-based study
P478volume142

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cites work (P2860)
Q31104346Adjuvant Radiation Therapy and Chemotherapy in Merkel Cell Carcinoma: Survival Analyses of 6908 Cases From the National Cancer Data Base
Q58761272Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness
Q38946809Complete spontaneous regression of Merkel cell carcinoma (1986-2016): a 30 year perspective
Q38868829Density, Distribution, and Composition of Immune Infiltrates Correlate with Survival in Merkel Cell Carcinoma
Q33720183Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma
Q47114351Evaluation of real-world treatment outcomes in patients with distant metastatic Merkel cell carcinoma following second-line chemotherapy in Europe
Q92576163Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain
Q47584286Immune evasion mechanisms and immune checkpoint inhibition in advanced merkel cell carcinoma
Q96127021Inhibition of PI3K by copanlisib exerts potent antitumor effects on Merkel cell carcinoma cell lines and mouse xenografts
Q38855025Merkel Cell Carcinoma Therapeutic Update
Q40100093Merkel Cell Carcinoma of the Head and Neck: Recommendations for Diagnostics and Treatment
Q54252123Merkel Cell Carcinoma: An Update and Immunotherapy.
Q61810298Merkel Cell Polyoma Viral Load and Intratumoral CD8+ Lymphocyte Infiltration Predict Overall Survival in Patients With Merkel Cell Carcinoma
Q89738686Merkel cell carcinoma
Q47658993Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics
Q57057523Multidimensional, quantitative assessment of PD-1/PD-L1 expression in patients with Merkel cell carcinoma and association with response to pembrolizumab
Q39926027Mutational landscape of MCPyV-positive and MCPyV-negative Merkel cell carcinomas with implications for immunotherapy.
Q38887303Rationale for immune-based therapies in Merkel polyomavirus-positive and -negative Merkel cell carcinomas
Q38671851Real-world treatment outcomes in patients with metastatic Merkel cell carcinoma treated with chemotherapy in the USA.
Q37321033Response rates and durability of chemotherapy among 62 patients with metastatic Merkel cell carcinoma
Q38738614Systematic literature review of efficacy, safety and tolerability outcomes of chemotherapy regimens in patients with metastatic Merkel cell carcinoma
Q57030149The biology and treatment of Merkel cell carcinoma: current understanding and research priorities
Q38721030Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival

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