scholarly article | Q13442814 |
P819 | ADS bibcode | 2012PLoSO...735513B |
P356 | DOI | 10.1371/JOURNAL.PONE.0035513 |
P932 | PMC publication ID | 3328460 |
P698 | PubMed publication ID | 22530037 |
P5875 | ResearchGate publication ID | 224822180 |
P50 | author | Peter J. Houghton | Q112045947 |
P2093 | author name string | Chenglong Li | |
Cheryl A London | |||
Jiayuh Lin | |||
Hemant K Bid | |||
Duane Oswald | |||
P2860 | cites work | Cardiac-specific activation of signal transducer and activator of transcription 3 promotes vascular formation in the heart. | Q54435115 |
STAT3 is activated in a subset of the Ewing sarcoma family of tumours. | Q54619002 | ||
Development and characterization of pediatric osteosarcoma xenografts | Q68759338 | ||
Inhibition of angiogenic differentiation of human umbilical vein endothelial cells by curcumin | Q74490421 | ||
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis | Q78836958 | ||
Stat3 promotes directional cell migration by regulating Rac1 activity via its activator betaPIX | Q84793774 | ||
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells | Q30492764 | ||
Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells | Q30493841 | ||
Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells | Q33289241 | ||
Characterization of STAT3 activation and expression in canine and human osteosarcoma | Q33417870 | ||
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors | Q33613105 | ||
The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells | Q33883721 | ||
A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells | Q33935165 | ||
Molecular characterization of the pediatric preclinical testing panel | Q34406965 | ||
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention | Q34595904 | ||
STAT3: a critical transcription activator in angiogenesis. | Q36801186 | ||
Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C. | Q36986233 | ||
The role of Ephs, Ephrins, and growth factors in Kaposi sarcoma and implications of EphrinB2 blockade | Q37039134 | ||
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis | Q38290076 | ||
Inhibition of growth and metastasis of human hepatocellular carcinoma by antisense oligonucleotide targeting signal transducer and activator of transcription 3. | Q38307015 | ||
STAT3-stathmin interactions control microtubule dynamics in migrating T-cells | Q39878474 | ||
Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program | Q40009993 | ||
Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program | Q40141410 | ||
VEGF differentially activates STAT3 in microvascular endothelial cells | Q44489900 | ||
Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation | Q47745076 | ||
The pediatric preclinical testing program: description of models and early testing results. | Q48387109 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | angiogenesis inhibitor | Q574834 |
P304 | page(s) | e35513 | |
P577 | publication date | 2012-04-17 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Anti-angiogenic activity of a small molecule STAT3 inhibitor LLL12. | |
P478 | volume | 7 |
Q58800840 | A novel small inhibitor, LLL12, targets STAT3 in non-small cell lung cancer and |
Q39225305 | Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines |
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Q33861173 | Development, characterization, and reversal of acquired resistance to the MEK1 inhibitor selumetinib (AZD6244) in an in vivo model of childhood astrocytoma |
Q36069142 | Gastric tumour-derived ANGPT2 regulation by DARPP-32 promotes angiogenesis |
Q34361391 | Initial solid tumor testing (stage 1) of AZD1480, an inhibitor of Janus kinases 1 and 2 by the pediatric preclinical testing program |
Q35977309 | Intravitreal dobesilate in the treatment of choroidal neovascularisation associated with age-related macular degeneration: report of two cases |
Q36626455 | Melittin derived peptides for nanoparticle based siRNA transfection |
Q38686229 | Monocytic microRNA profile associated with coronary collateral artery function in chronic total occlusion patients. |
Q41660975 | Myeloperoxidase oxidized LDL interferes with endothelial cell motility through miR-22 and heme oxygenase 1 induction: possible involvement in reendothelialization of vascular injuries |
Q35835942 | Novel Etoposide Analogue Modulates Expression of Angiogenesis Associated microRNAs and Regulates Cell Proliferation by Targeting STAT3 in Breast Cancer. |
Q90480455 | Overexpression of miR-206 in osteosarcoma and its associated molecular mechanisms as assessed through TCGA and GEO databases |
Q35540652 | Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration |
Q40471161 | Protective effect of suppressing STAT3 activity in LPS-induced acute lung injury |
Q35130808 | RECK controls breast cancer metastasis by modulating a convergent, STAT3-dependent neoangiogenic switch |
Q38265472 | STAT3 as a possible therapeutic target in human malignancies: lessons from acute myeloid leukemia |
Q28538093 | Synthesis and mechanistic studies of a novel homoisoflavanone inhibitor of endothelial cell growth |
Q38657451 | Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. |
Q27014674 | Targeting SH2 domains in breast cancer |
Q91565659 | Targeting Tumor Microenvironment by Small-Molecule Inhibitors |
Q36918007 | The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma |
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