Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation

scientific article

Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M301866200
P698PubMed publication ID12874294

P50authorMichael DetmarQ64867609
P2093author name stringYasushi Hanakawa
Koji Hashimoto
Koji Sayama
Yuji Shirakata
Kenshi Yamasaki
Yoko Yahata
Sho Tokumaru
P2860cites workSignal transducer and activator of transcription 3 is required for glycoprotein 130-mediated induction of vascular endothelial growth factor in cardiac myocytesQ22253414
Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factorQ24294262
Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1Q24310533
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesisQ24313372
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formationQ24316945
The fms-like tyrosine kinase, a receptor for vascular endothelial growth factorQ24328901
Ectodomain shedding of epidermal growth factor receptor ligands is required for keratinocyte migration in cutaneous wound healingQ24677883
Recent developments in the cell biology of basic fibroblast growth factorQ24679568
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethalityQ24685515
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteinsQ27860890
Induction of epithelial tubules by growth factor HGF depends on the STAT pathwayQ28259695
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesisQ28300359
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryoQ28586040
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endotheliumQ28587604
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3Q28588628
Failure of blood-island formation and vasculogenesis in Flk-1-deficient miceQ28593600
Heterozygous embryonic lethality induced by targeted inactivation of the VEGF geneQ29547732
Abnormal blood vessel development and lethality in embryos lacking a single VEGF alleleQ29547733
STATs and gene regulationQ29547796
The biology of vascular endothelial growth factorQ29615946
Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genomeQ33557797
Role of vascular endothelial growth factor in the regulation of angiogenesisQ33723796
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cellsQ34047111
A novel role for STAT3 in cardiac remodelingQ34245507
A requirement for Flk1 in primitive and definitive hematopoiesis and vasculogenesisQ34430479
Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factorQ37368189
STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell lineQ37625031
STATs: signal transducers and activators of transcriptionQ40974978
Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesisQ42679964
Signaling vascular morphogenesis and maintenanceQ45058276
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cellsQ50336697
Signal relays in the VEGF system.Q52180099
Cytokine-receptor complexes as chaperones for nuclear translocation of signal transducers.Q53988117
P433issue41
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
microvascular endothelial cellQ107137234
phosphorylationQ242736
microvesselQ6840468
P304page(s)40026-40031
P577publication date2003-07-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleNuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation
P478volume278

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