Two serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells

scientific article published on 9 June 2017

Two serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OL.2017.6363
P932PMC publication ID5530184
P698PubMed publication ID28781685

P2093author name stringZhihao Wu
Qinghua Zhou
Huijun Wei
Lili Guo
Zhijian Zhang
Jiangnan Ge
P2860cites workGlobal cancer statisticsQ22241238
Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1Q24635316
A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potentialQ28256649
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PIAS3 expression in squamous cell lung cancer is low and predicts overall survivalQ30405870
A phosphopeptide mimetic prodrug targeting the SH2 domain of Stat3 inhibits tumor growth and angiogenesis.Q33661939
PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status.Q34352295
Nm23/nucleoside diphosphate kinase in human cancersQ34478573
STAT3 signaling: anticancer strategies and challenges.Q34715455
Histidine kinases and histidine phosphorylated proteins in mammalian cell biology, signal transduction and cancerQ35048896
Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.Q35081777
Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3.Q35869426
Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic functionQ36662693
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.Q36691086
SOCS regulation of the JAK/STAT signalling pathwayQ37003892
Signal transducer and activator of transcription 3 (STAT3): a promising target for anticancer therapyQ37869903
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesisQ38290076
Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanismQ38316383
Mitochondrial reactive oxygen species mediates nicotine-induced hypoxia-inducible factor-1α expression in human non-small cell lung cancer cellsQ39393739
Fra-1 and Stat3 synergistically regulate activation of human MMP-9 geneQ40119235
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathwaysQ40399370
Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasisQ47677996
Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formationQ47745076
Activation of stat3 in human melanoma promotes brain metastasisQ48616814
Roles of EGFR-Stat3 signal pathway in carcinogenesis of experimental hepatoma in rats.Q53341202
[Construction and expression of nm23-H1 gene with different enzyme activities and resistant specific shRNA in eukaryotic expression vector].Q55426895
Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasisQ64379437
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasisQ78836958
P433issue2
P304page(s)2475-2482
P577publication date2017-06-09
P1433published inOncology LettersQ20640514
P1476titleTwo serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells
P478volume14

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cites work (P2860)
Q50105737Systematic analysis of gene expression alterations and clinical outcomes of STAT3 in cancer
Q47336124The actions of NME1/NDPK-A and NME2/NDPK-B as protein kinases

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