VEGF-mediated STAT3 activation inhibits retinal vascularization by down-regulating local erythropoietin expression

scientific article

VEGF-mediated STAT3 activation inhibits retinal vascularization by down-regulating local erythropoietin expression is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.AJPATH.2011.11.031
P932PMC publication ID3349887
P698PubMed publication ID22230249
P5875ResearchGate publication ID221733879

P2093author name stringHaibo Wang
M Elizabeth Hartnett
Yanchao Jiang
Grace Byfield
George Wesley Smith
Manabu McCloskey
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Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathwaysQ40399370
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Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neurogliaQ41677354
Neutralizing antibody to VEGF reduces intravitreous neovascularization and may not interfere with ongoing intraretinal vascularization in a rat model of retinopathy of prematurity.Q41829449
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Reduction in endothelial tip cell filopodia corresponds to reduced intravitreous but not intraretinal vascularization in a model of ROP.Q42577163
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VEGF differentially activates STAT3 in microvascular endothelial cellsQ44489900
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Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formationQ47745076
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Brain structure and neurocognitive and behavioural function in adolescents who were born very pretermQ48206315
Higher cumulative doses of erythropoietin and developmental outcomes in preterm infantsQ48447815
Predictors of short-term visual outcome after anti-VEGF therapy of macular edema due to central retinal vein occlusion.Q53260323
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Effects of intraocular or systemic administration of neutralizing antibody against vascular endothelial growth factor on the murine experimental model of retinopathyQ58207697
Prognostic factors in the natural course of retinopathy of prematurity. The Cryotherapy for Retinopathy of Prematurity Cooperative GroupQ70571517
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Oxygen-induced retinopathy in the rat: relationship of retinal nonperfusion to subsequent neovascularizationQ72120451
The effect of oxygen on vasoformative cell division. Evidence that 'physiological hypoxia' is the stimulus for normal retinal vasculogenesisQ72298016
Exposure to alternating hypoxia and hyperoxia causes severe proliferative retinopathy in the newborn ratQ72650581
Therapeutic effect of liposomal superoxide dismutase in an animal model of retinopathy of prematurityQ73298393
Genetic susceptibility to retinopathy of prematurityQ79322970
Retinopathy of prematurityQ79858093
Differential role of Jak-STAT signaling in retinal degenerationsQ80243609
Angiostatic effect of penetrating ocular injury: role of pigment epithelium-derived factorQ82129963
[Retinopathy of prematurity and oxidative stress]Q82776670
Association between higher cumulative doses of recombinant erythropoietin and risk for retinopathy of prematurityQ83296386
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecterythropoietinQ218706
P304page(s)1243-1253
P577publication date2012-01-09
P1433published inThe American Journal of PathologyQ4744259
P1476titleVEGF-mediated STAT3 activation inhibits retinal vascularization by down-regulating local erythropoietin expression
P478volume180

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cites work (P2860)
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Q38560836VEGFA activates erythropoietin receptor and enhances VEGFR2-mediated pathological angiogenesis

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