| scholarly article | Q13442814 |
| P50 | author | Jean-Luc Puel | Q63442217 |
| P2093 | author name string | C Bonny | |
| J Wang | |||
| F de Ribaupierre | |||
| A Zine | |||
| T R Van De Water | |||
| P2860 | cites work | JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 |
| Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction | Q25938986 | ||
| Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation | Q28131755 | ||
| Signal transduction by the JNK group of MAP kinases | Q28142592 | ||
| Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development | Q28268881 | ||
| c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities | Q28291350 | ||
| Transcription factor ATF2 regulation by the JNK signal transduction pathway | Q28305631 | ||
| Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation | Q28378559 | ||
| POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. | Q28567147 | ||
| A cytoplasmic inhibitor of the JNK signal transduction pathway | Q28586970 | ||
| Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway | Q29616436 | ||
| The stress-activated protein kinase subfamily of c-Jun kinases | Q29620001 | ||
| Intense noise-induced apoptosis in hair cells of guinea pig cochleae | Q33180225 | ||
| Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death | Q33930576 | ||
| Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats | Q36895149 | ||
| Dose-dependent response of vestibular hair cells of guinea pigs following streptomycin ototoxiation | Q36898325 | ||
| Cellular pattern and nerve supply of the human organ of Corti | Q38587929 | ||
| Inhibition of the c-Jun N-terminal kinase signaling pathway influences neurite outgrowth of spiral ganglion neurons in vitro | Q40621038 | ||
| Tissue-specific levels and cellular distribution of epidermal growth factor receptors within control and neomycin-damaged neonatal rat Organ of Corti | Q40823953 | ||
| L- and D- methionine provide equivalent long term protection against CDDP-induced ototoxicity in vivo, with partial in vitro and in vivo retention of antineoplastic activity | Q40913217 | ||
| Oxygen radicals and signaling | Q41750986 | ||
| Activity profile of calpains I and II in chronically infarcted rat myocardium--influence of the calpain inhibitor CAL 9961. | Q41981503 | ||
| Involvement of apoptosis in progression of cochlear lesion following exposure to intense noise | Q42522327 | ||
| Rescue of auditory hair cells from aminoglycoside toxicity by Clostridium difficile toxin B, an inhibitor of the small GTPases Rho/Rac/Cdc42. | Q42526586 | ||
| CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo. | Q42536543 | ||
| Identification of the critical features of a small peptide inhibitor of JNK activity | Q42667595 | ||
| Periods of sensitivity to antibiotic treatment | Q43414662 | ||
| Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family. | Q43590657 | ||
| Round window membrane delivery of L-methionine provides protection from cisplatin ototoxicity without compromising chemotherapeutic efficacy | Q43639242 | ||
| Inhibition of the c-Jun N-terminal kinase signaling pathway by the mixed lineage kinase inhibitor CEP-1347 (KT7515) preserves metabolism and growth of trophic factor-deprived neurons. | Q43833728 | ||
| Riluzole rescues cochlear sensory cells from acoustic trauma in the guinea-pig. | Q44006429 | ||
| Reactive oxygen species in chick hair cells after gentamicin exposure in vitro | Q45104194 | ||
| Attenuation of aminoglycoside-induced cochlear damage with the metabolic antioxidant alpha-lipoic acid | Q46142273 | ||
| Outer hair cell loss and supporting cell expansion following chronic gentamicin treatment | Q46242957 | ||
| Electrophysiological and morphological correlates in the guinea pig cochlea after exposure to 'impulsive' noise. | Q46352081 | ||
| Replacement of mammalian auditory hair cells. | Q50506403 | ||
| Formation of free radicals by gentamicin and iron and evidence for an iron/gentamicin complex. | Q50517643 | ||
| Sulfhydryl compounds and antioxidants inhibit cytotoxicity to outer hair cells of a gentamicin metabolite in vitro. | Q50524541 | ||
| Apoptosis of guinea pig cochlear hair cells following chronic aminoglycoside treatment. | Q52530430 | ||
| Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals | Q58415331 | ||
| A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus | Q63343005 | ||
| Biphasic and synergistic activation of p44mapk (ERK1) by growth factors: correlation between late phase activation and mitogenicity | Q68149927 | ||
| Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants | Q71703824 | ||
| Development of the inner ear of the mouse: a radioautographic study of terminal mitoses | Q72334432 | ||
| EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor | Q72787935 | ||
| Apoptotic death of hair cells in mammalian vestibular sensory epithelia | Q73280956 | ||
| Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway | Q73977274 | ||
| Blockade of c-Jun N-terminal kinase pathway attenuates gentamicin-induced cochlear and vestibular hair cell death | Q74293270 | ||
| Amikacin intoxication induces apoptosis and cell proliferation in rat organ of Corti | Q74344658 | ||
| P433 | issue | 24 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell death | Q2383867 |
| hearing loss | Q16035842 | ||
| P304 | page(s) | 8596-8607 | |
| P577 | publication date | 2003-09-01 | |
| P1433 | published in | Journal of Neuroscience | Q1709864 |
| P1476 | title | A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss | |
| P478 | volume | 23 |
| Q30417680 | A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity |
| Q42492730 | A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance. |
| Q89723888 | ASK1 inhibition: a therapeutic strategy with multi-system benefits |
| Q30472512 | Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure |
| Q30498939 | Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy |
| Q30482911 | Adenosine and the auditory system. |
| Q30419038 | Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway |
| Q91811018 | Advances and Challenges in Pharmaceutical Therapies to Prevent and Repair Cochlear Injuries From Noise |
| Q92958757 | Adverse outcome pathway for aminoglycoside ototoxicity in drug-resistant tuberculosis treatment |
| Q26797403 | Age-related hearing impairment and the triad of acquired hearing loss |
| Q90595610 | Aminoglycoside- and Cisplatin-Induced Ototoxicity: Mechanisms and Otoprotective Strategies |
| Q30499378 | Aminoglycoside-induced degeneration of adult spiral ganglion neurons involves differential modulation of tyrosine kinase B and p75 neurotrophin receptor signaling. |
| Q30482886 | Apoptosis-related genes change their expression with age and hearing loss in the mouse cochlea |
| Q30447104 | Assessment of the risk factors for hearing loss in adult Nigerian population |
| Q38611496 | Bioinformatics analysis of gene expression profiling for identification of potential key genes among ischemic stroke |
| Q30473659 | Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32. |
| Q30437957 | Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain |
| Q30447637 | Cisplatin and aminoglycoside antibiotics: hearing loss and its prevention |
| Q30406115 | Comparative analysis of combination kanamycin-furosemide versus kanamycin alone in the mouse cochlea |
| Q29304409 | Compounds for the prevention and treatment of noise-induced hearing loss |
| Q30473044 | Current aspects of hearing loss from occupational and leisure noise |
| Q89565336 | D-Galactose-induced oxidative stress and mitochondrial dysfunction in the cochlear basilar membrane: an in vitro aging model |
| Q46607400 | Damage-induced activation of ERK1/2 in cochlear supporting cells is a hair cell death-promoting signal that depends on extracellular ATP and calcium. |
| Q57456573 | Decreased Expression of TRPV4 Channels in HEI-OC1 Cells Induced by High Glucose Is Associated with Hearing Impairment |
| Q30450204 | Development of an intracellularly acting inhibitory peptide selective for PKN. |
| Q30402748 | Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding |
| Q30480619 | Differential expression of apoptosis-related genes in the cochlea of noise-exposed rats |
| Q33847686 | Early investigational drugs for hearing loss |
| Q115406968 | Ectopic expression of ROR1 prevents cochlear hair cell loss in guinea pigs with noise‐induced hearing loss |
| Q64113323 | Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice |
| Q91979131 | Efficacy and Safety of AM-111 in the Treatment of Acute Unilateral Sudden Deafness-A Double-blind, Randomized, Placebo-controlled Phase 3 Study |
| Q30452815 | Efficacy of three drugs for protecting against gentamicin-induced hair cell and hearing losses |
| Q30480487 | Elucidation of separate, but collaborative functions of the rRNA methyltransferase-related human mitochondrial transcription factors B1 and B2 in mitochondrial biogenesis reveals new insight into maternally inherited deafness |
| Q38850515 | Emerging Therapies for Sensorineural Hearing Loss. |
| Q30240239 | Emerging therapeutic interventions against noise-induced hearing loss |
| Q24630807 | Emerging treatments for noise-induced hearing loss |
| Q30368370 | Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line |
| Q30474951 | Future approaches for inner ear protection and repair |
| Q30488706 | Genetic analysis of interactions with eukaryotic rRNA identify the mitoribosome as target in aminoglycoside ototoxicity |
| Q30492550 | Heat shock inhibits both aminoglycoside- and cisplatin-induced sensory hair cell death |
| Q50354400 | Histopathological and audiological effects of mechanical trauma associated with the placement of an intracochlear electrode, and the benefit of corticosteroid infusion: prospective animal study |
| Q30481278 | Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (Danio rerio) lateral line and mouse (Mus musculus) utricle |
| Q30362202 | Immune defense is the primary function associated with the differentially expressed genes in the cochlea following acoustic trauma |
| Q30382377 | Increased Sensitivity to Noise-Induced Hearing Loss by Blockade of Endogenous PI3K/Akt Signaling. |
| Q46595284 | Induction of proapoptotic Daxx following ischemic acute kidney injury |
| Q92423959 | Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside- and cisplatin-induced hair cell death |
| Q41827137 | Inhibitors of Histone Deacetylases Attenuate Noise-Induced Hearing Loss |
| Q33304105 | Inhibitors of c-Jun N-terminal kinases: JuNK no more? |
| Q30484636 | Inner ear drug delivery for auditory applications |
| Q30454411 | Intracellular mechanisms of aminoglycoside-induced cytotoxicity. |
| Q50098907 | Is there a close relationship between changes in amplitudes of distortion product otoacoustic emissions and hair cell damage after exposure to realistic industrial noise in guinea pigs? |
| Q27320018 | JNK Inhibition Inhibits Lateral Line Neuromast Hair Cell Development |
| Q30489783 | JNK signaling in neomycin-induced vestibular hair cell death |
| Q36281565 | Keynote review: The auditory system, hearing loss and potential targets for drug development. |
| Q30489671 | Local inner-ear drug delivery and pharmacokinetics. |
| Q30392973 | Loss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors |
| Q28393038 | Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection |
| Q30500834 | Mechanisms of noise-induced hearing loss indicate multiple methods of prevention |
| Q30412447 | Mechanisms of sensorineural cell damage, death and survival in the cochlea. |
| Q28296128 | Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale |
| Q30414386 | Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma |
| Q30409983 | Nanoparticle mediated drug delivery of rolipram to tyrosine kinase B positive cells in the inner ear with targeting peptides and agonistic antibodies. |
| Q64225613 | Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity |
| Q24599985 | New developments in aminoglycoside therapy and ototoxicity |
| Q38384722 | New treatment options for hearing loss. |
| Q30466128 | Noise-induced changes in gene expression in the cochleae of mice differing in their susceptibility to noise damage |
| Q41526695 | Non-autonomous Cellular Responses to Ototoxic Drug-Induced Stress and Death |
| Q30368888 | On the Horizon: Cochlear Implant Technology. |
| Q91625325 | Otoprotectants: From Research to Clinical Application |
| Q36281577 | Ototoxicity: therapeutic opportunities |
| Q42482496 | Overexpression of X-linked inhibitor of apoptosis protein protects against noise-induced hearing loss in mice |
| Q45908531 | PI3K and Inhibitor of Apoptosis Proteins Modulate Gentamicin- Induced Hair Cell Death in the Zebrafish Lateral Line. |
| Q38736119 | Pharmacological agents used for treatment and prevention in noise-induced hearing loss |
| Q45069589 | Phenotypic Optimization of Urea-Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss |
| Q30476336 | Pivotal role of Harakiri in the induction and prevention of gentamicin-induced hearing loss |
| Q44920105 | Progression of hair cell ejection and molecular markers of apoptosis in the avian cochlea following gentamicin treatment |
| Q30460365 | Protection from impulse noise-induced hearing loss with novel Src-protein tyrosine kinase inhibitors |
| Q64965227 | Purinergic Signaling and Aminoglycoside Ototoxicity: The Opposing Roles of P1 (Adenosine) and P2 (ATP) Receptors on Cochlear Hair Cell Survival. |
| Q85822839 | Quantitative proteomics reveals dynamic interaction of c-Jun N-terminal kinase (JNK) with RNA transport granule proteins splicing factor proline- and glutamine-rich (Sfpq) and non-POU domain-containing octamer-binding protein (Nono) during neuronal |
| Q30446590 | Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line |
| Q88968384 | Resistance to neomycin ototoxicity in the extreme basal (hook) region of the mouse cochlea |
| Q30474223 | Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways |
| Q30366115 | Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy |
| Q30420217 | Round window membrane intracochlear drug delivery enhanced by induced advection. |
| Q90258361 | Screening Mammalian Cochlear Hair Cells to Identify Critical Processes in Aminoglycoside-Mediated Damage |
| Q30454013 | Screening for chemicals that affect hair cell death and survival in the zebrafish lateral line |
| Q30459150 | Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. |
| Q30367228 | Sound-Induced Intracellular Ca2+ Dynamics in the Adult Hearing Cochlea |
| Q37271376 | State-of-the-art mechanisms of intracochlear drug delivery. |
| Q21129270 | Strategies for developing novel therapeutics for sensorineural hearing loss |
| Q38676720 | The Role of MicroRNAs in Environmental Risk Factors, Noise-Induced Hearing Loss, and Mental Stress. |
| Q30487015 | The adult mouse utricle as an in vitro preparation for studies of ototoxic-drug-induced sensory hair cell death |
| Q30500831 | The c-jun kinase/stress-activated pathway: regulation, function and role in human disease |
| Q30465748 | The design and screening of drugs to prevent acquired sensorineural hearing loss |
| Q30454726 | The impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium |
| Q30457564 | The miR-183/Taok1 target pair is implicated in cochlear responses to acoustic trauma |
| Q59793891 | Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency |
| Q30473039 | Therapy of hearing disorders - conservative procedures. |
| Q28505223 | Tmprss3, a transmembrane serine protease deficient in human DFNB8/10 deafness, is critical for cochlear hair cell survival at the onset of hearing |
| Q50458358 | Ultrastructural analysis of aminoglycoside-induced hair cell death in the zebrafish lateral line reveals an early mitochondrial response. |
| Q30423728 | XG-102 administered to healthy male volunteers as a single intravenous infusion: a randomized, double-blind, placebo-controlled, dose-escalating study |
| Q50453643 | [Protection and regeneration of sensory epithelia of the inner ear]. |
| Q89621699 | c-Jun N-Terminal Kinase Signaling Inhibitors Under Development |
| Q30382124 | c-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea. |
| Q30394383 | β-Catenin is central to DUX4-driven network rewiring in facioscapulohumeral muscular dystrophy. |
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