The impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium

scientific article

The impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/JIR.S40092
P8608Fatcat IDrelease_mfj2iyxfdffullkbpybjg3tzim
P932PMC publication ID3650567
P698PubMed publication ID23667316
P5875ResearchGate publication ID236693087

P50authorIngo StrickerQ115686185
P2093author name stringWaldemar Uhl
Thomas Herdegen
Ansgar M Chromik
Christoph Hilgert
Jonas Kersting
Kirstin Reinecke
Monika S Janot
Sabine Kersting
Volker Behrendt
P2860cites workSignal transduction by the JNK group of MAP kinasesQ28142592
Anti-interleukin-12 antibody for active Crohn's diseaseQ28292686
Signalling pathways and molecular interactions of NOD1 and NOD2Q28298636
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinaseQ28364720
The JNK inhibitor XG-102 protects against TNBS-induced colitisQ28481470
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responsesQ28588300
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammationQ29614227
Cytokine therapy for Crohn's disease: advances in translational researchQ30442580
Infliximab for the treatment of fistulas in patients with Crohn's diseaseQ33860666
Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study GroupQ33927770
Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell deathQ33930576
Inhibition of stress-activated MAP kinases induces clinical improvement in moderate to severe Crohn's diseaseQ33956768
Therapeutic and prophylactic thalidomide in TNBS-induced colitis: synergistic effects on TNF-alpha, IL-12 and VEGF productionQ34098863
Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium.Q50517017
Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.Q53540951
A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell NucleusQ63343005
Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)Q70823350
Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependencyQ73169545
Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitisQ73675999
Preliminary evaluation of safety and activity of recombinant human interleukin 11 in patients with active Crohn's diseaseQ77921868
p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel diseaseQ78058025
Genetic deletion of JNK1 and JNK2 aggravates the DSS-induced colitis in miceQ79965155
The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitisQ83185411
A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss.Q34247022
MAP kinases in the immune responseQ34542231
The immunology of mucosal models of inflammationQ34542265
Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets.Q35023644
Update in inflammatory bowel disease pathogenesisQ36036554
Role of MAP kinase-dependent apoptotic pathway in innate immune responses and viral infectionQ36501681
Critical appraisal of the current practice in murine TNBS-induced colitisQ36609213
Knockout of the c-Jun N-terminal Kinase 2 aggravates the development of mild chronic dextran sulfate sodium colitis independently of expression of intestinal cytokines TNFα, TGFB1, and IL-6.Q36620448
Role of the JNK signal transduction pathway in inflammatory bowel diseaseQ37054358
Distinct cytokine patterns identified from multiplex profiles of murine DSS and TNBS-induced colitisQ37098695
Mitogen activated protein kinases: a role in inflammatory bowel disease?Q37605958
The JNK inhibitor XG-102 protects from ischemic damage with delayed intravenous administration also in the presence of recombinant tissue plasminogen activatorQ40055054
Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.Q40448426
Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel diseaseQ40491913
Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice.Q41418413
Reduced susceptibility of mice overexpressing transforming growth factor alpha to dextran sodium sulphate induced colitisQ41820837
Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokinesQ42464997
A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance.Q42492730
Clinicopathologic study of dextran sulfate sodium experimental murine colitis.Q42506472
Chemically induced mouse models of intestinal inflammationQ42510602
Inflammatory signal transduction in Crohn's disease and novel therapeutic approachesQ42525644
c-Jun NH(2)-terminal kinase (JNK)1 and JNK2 have distinct roles in CD8(+) T cell activationQ42944720
A peptide inhibitor of c-Jun N-terminal kinase for the treatment of endotoxin-induced uveitisQ43099140
JNK inhibition and inflammation after cerebral ischemiaQ43244845
Randomized, controlled trial of recombinant human interleukin-11 in patients with active Crohn's diseaseQ43904258
A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemiaQ44560865
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in miceQ44753508
The incidence of inflammatory bowel disease in a rural region of Southern Germany: a prospective population-based studyQ46206143
Oral administration of taurolidine ameliorates chronic DSS colitis in miceQ46922561
A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivoQ47310567
Involvement of CD4+ T cells in the development of dextran sulfate sodium-induced experimental colitis and suppressive effect of IgG on their actionQ47691185
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectmurine modelQ122890741
P304page(s)71-81
P577publication date2013-05-03
P1433published inJournal of Inflammation ResearchQ6295349
P1476titleThe impact of JNK inhibitor D-JNKI-1 in a murine model of chronic colitis induced by dextran sulfate sodium
P478volume6

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cites work (P2860)
Q60915735Anti-Inflammatory Effect of IL-37-Producing T-Cell Population in DSS-Induced Chronic Inflammatory Bowel Disease in Mice
Q48259906Impaired resolution of DSS-induced colitis in mice lacking the glucocorticoid receptor in myeloid cells.
Q27023869JNK signalling in cancer: in need of new, smarter therapeutic targets
Q34719329Molecular mechanism of protopanaxadiol saponin fraction-mediated anti-inflammatory actions
Q39578562Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation
Q28543472Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach
Q51653926Role of C-Jun N-terminal Kinase in Hepatocellular Carcinoma Development.
Q46474665Role of pregnane X-receptor in regulating bacterial translocation in chronic liver diseases
Q93028197Selective inhibitors for JNK signalling: a potential targeted therapy in cancer
Q38399146Therapeutic potential of tonsil-derived mesenchymal stem cells in dextran sulfate sodium-induced experimental murine colitis
Q55005402c-Jun N-terminal kinase 2 promotes enterocyte survival and goblet cell differentiation in the inflamed intestine.

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