A cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma

scientific article

A cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.27275
P932PMC publication ID4176525
P698PubMed publication ID24954865
P5875ResearchGate publication ID263323861

P50authorMark J. OlsenQ73035272
P2093author name stringXiaoqun Dong
Qi Tang
Jack R Wands
Qiushi Lin
Arihiro Aihara
Chiung-Kuei Huang
Waihong Chung
P2860cites workCloning and increased expression of an insulin receptor substrate - 1-like gene in human hepatocellular carcinomaQ24328787
Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinomaQ24562001
Sorafenib in advanced hepatocellular carcinomaQ27861075
Overexpression of human aspartyl (asparaginyl) beta-hydroxylase is associated with malignant transformationQ28139424
Antisense oligodeoxynucleotides directed against aspartyl (asparaginyl) β-hydroxylase suppress migration of cholangiocarcinoma cellsQ28201030
Role of the aspartyl-asparaginyl-beta-hydroxylase gene in neuroblastoma cell motilityQ28214662
Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liverQ28246572
Partial purification and characterization of bovine liver aspartyl beta-hydroxylaseQ28246732
Aspartyl-(asparaginyl)-beta-hydroxylase regulates hepatocellular carcinoma invasivenessQ28303764
The canonical Notch signaling pathway: unfolding the activation mechanismQ29547725
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trialQ29547903
Notch signalling: a simple pathway becomes complexQ29555851
Prognostic value of humbug gene overexpression in stage II colon cancerQ33259349
Ethanol inhibition of aspartyl-asparaginyl-beta-hydroxylase in fetal alcohol spectrum disorder: potential link to the impairments in central nervous system neuronal migrationQ33944605
cDNA cloning and expression of bovine aspartyl (asparaginyl) beta-hydroxylaseQ34249628
An analysis of 412 cases of hepatocellular carcinoma at a Western centerQ34503813
EGF-like domains in extracellular matrix proteins: localized signals for growth and differentiation?Q34504931
The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinomaQ34612059
Notch signaling, gamma-secretase inhibitors, and cancer therapyQ34653560
Tumor progression-related transmembrane protein aspartate-β-hydroxylase is a target for immunotherapy of hepatocellular carcinomaQ35894880
Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in miceQ36421780
Signal transduction cascades and hepatitis B and C related hepatocellular carcinomaQ36455499
Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinomaQ36881080
Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinomaQ36997259
siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growthQ37023897
Generation and regeneration of cells of the liver and pancreasQ37341344
The role of signaling pathways in the development and treatment of hepatocellular carcinomaQ37773788
Deregulation of signalling pathways in prognostic subtypes of hepatocellular carcinoma: novel insights from interspecies comparisonQ38080061
The selective Aurora B kinase inhibitor AZD1152 as a novel treatment for hepatocellular carcinoma.Q39774631
Overexpression of aspartyl-(asparaginyl)-beta-hydroxylase in hepatocellular carcinoma is associated with worse surgical outcomeQ43005656
Notch signaling in hepatocellular carcinoma: guilty in association!Q43239248
Constitutive Notch2 signaling induces hepatic tumors in miceQ44601154
A critical role for notch signaling in the formation of cholangiocellular carcinomas.Q50945875
Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms.Q54590341
Bovine liver aspartyl beta-hydroxylase. Purification and characterizationQ67920946
Activation of mitogen-activated protein kinases/extracellular signal-regulated kinases in human hepatocellular carcinomaQ74428408
WNT/β-catenin signaling and hepatocellular carcinomaQ87469831
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
hepatocellular carcinomaQ1148337
P304page(s)1302-1313
P577publication date2014-08-25
P1433published inHepatologyQ15724398
P1476titleA cell-surface β-hydroxylase is a biomarker and therapeutic target for hepatocellular carcinoma
P478volume60

Reverse relations

cites work (P2860)
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Q92332826Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway
Q37485171Aspartate-β-hydroxylase (ASPH): A potential therapeutic target in human malignant gliomas
Q35091441Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma
Q95840325Aspartate/asparagine-β-hydroxylase: a high-throughput mass spectrometric assay for discovery of small molecule inhibitors
Q59354375Construction and Characterization of Adenovirus Vectors Encoding Aspartate--Hydroxylase to Preliminary Application in Immunotherapy of Hepatocellular Carcinoma
Q47331366Ethanol-Induced White Matter Atrophy Is Associated with Impaired Expression of Aspartyl-Asparaginyl-β-Hydroxylase (ASPH) and Notch Signaling in an Experimental Rat Model
Q35767923High level of intercellular adhesion molecule-1 affects prognosis of patients with hepatocellular carcinoma
Q55378664Hydroxylase Activity of ASPH Promotes Hepatocellular Carcinoma Metastasis Through Epithelial-to-Mesenchymal Transition Pathway.
Q89926103Kinetic parameters of human aspartate/asparagine-β-hydroxylase suggest that it has a possible function in oxygen sensing
Q42366399Lambda phage-based vaccine induces antitumor immunity in hepatocellular carcinoma
Q54111731MiR-200a inhibits cell proliferation and EMT by down-regulating the ASPH expression levels and affecting ERK and PI3K/Akt pathways in human hepatoma cells.
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Q90127696Prometastatic Secretome Trafficking via Exosomes Initiates Pancreatic Cancer Pulmonary Metastasis
Q34599527Proteomic profile and in silico analysis in metastatic melanoma with and without BRAF mutation
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Q36853891Upregulation of colonic and hepatic tumor overexpressed gene is significantly associated with the unfavorable prognosis marker of human hepatocellular carcinoma

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