Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma

scientific article published on 12 February 2019

Anti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CANLET.2019.02.006
P932PMC publication ID6411448
P698PubMed publication ID30768955

P2093author name stringXiaoqun Dong
Jack R Wands
Rolf I Carlson
Michael S Lebowitz
Zhi-Gang Jiang
Hossein Ghanbari
Yanmei Zhou
Xuewei Bai
Kosuke Ogawa
Katsuya Nagaoka
Songhua Zhang
Steve Fuller
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Notch signaling: cell fate control and signal integration in developmentQ27861061
Overexpression of human aspartyl (asparaginyl) beta-hydroxylase is associated with malignant transformationQ28139424
Antisense oligodeoxynucleotides directed against aspartyl (asparaginyl) β-hydroxylase suppress migration of cholangiocarcinoma cellsQ28201030
Role of the aspartyl-asparaginyl-beta-hydroxylase gene in neuroblastoma cell motilityQ28214662
Prognostic value of humbug gene overexpression in stage II colon cancerQ33259349
Isolation and characterization of human antibodies targeting human aspartyl (asparaginyl) beta-hydroxylaseQ33323345
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Aspartate β-Hydroxylase expression promotes a malignant pancreatic cellular phenotypeQ35176052
Immunization with aspartate-β-hydroxylase-loaded dendritic cells produces antitumor effects in a rat model of intrahepatic cholangiocarcinomaQ35624314
Tumor progression-related transmembrane protein aspartate-β-hydroxylase is a target for immunotherapy of hepatocellular carcinomaQ35894880
Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression.Q35949450
Activation of signal transduction pathways during hepatic oncogenesisQ36386273
Aspartate β-hydroxylase modulates cellular senescence through glycogen synthase kinase 3β in hepatocellular carcinomaQ36723189
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Overexpression of aspartyl-(asparaginyl)-beta-hydroxylase in hepatocellular carcinoma is associated with worse surgical outcomeQ43005656
Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer.Q45928785
Overexpression of HER2/neu oncogene in human pancreatic carcinomaQ46060370
Determination of subcutaneous tumor size in athymic (nude) miceQ46296687
Phase II study of the antibody-drug conjugate TAK-264 (MLN0264) in patients with metastatic or recurrent adenocarcinoma of the stomach or gastroesophageal junction expressing guanylyl cyclase C.Q51141565
A phase II study of antibody-drug conjugate, TAK-264 (MLN0264) in previously treated patients with advanced or metastatic pancreatic adenocarcinoma expressing guanylyl cyclase C.Q53280066
Overexpression of the HER-2/neu oncogene in pancreatic adenocarcinoma.Q54398738
Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms.Q54590341
Pancreatic AdenocarcinomaQ55880513
Quantification of histochemical staining by color deconvolutionQ74448733
Clinicopathological correlates of aspartyl (asparaginyl) beta-hydroxylase over-expression in cholangiocarcinomaQ80998517
Copy number of chromosome 17 but not HER2 amplification predicts clinical outcome of patients with pancreatic ductal adenocarcinomaQ81073375
Pancreatic ductal adenocarcinoma: is there a survival difference for R1 resections versus locally advanced unresectable tumors? What is a "true" R0 resection?Q84961795
P4510describes a project that usesImageJQ1659584
P921main subjectinvasive ductal carcinomaQ1671685
pancreatic ductal carcinomaQ8263002
pancreatic ductal adenocarcinomaQ18555956
P304page(s)87-98
P577publication date2019-02-12
P1433published inCancer LettersQ326372
P1476titleAnti-tumor activity of antibody drug conjugate targeting aspartate-β-hydroxylase in pancreatic ductal adenocarcinoma
P478volume449