scholarly article | Q13442814 |
P50 | author | Tamás Freund | Q1003857 |
István Katona | Q38320341 | ||
P2860 | cites work | Homer Binds TRPC Family Channels and Is Required for Gating of TRPC1 by IP3 Receptors | Q24295021 |
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain | Q24299523 | ||
Brain monoglyceride lipase participating in endocannabinoid inactivation | Q24533828 | ||
Cannabinoid receptor localization in brain | Q24558751 | ||
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects | Q24569799 | ||
Activity-dependent regulation of synapses by retrograde messengers | Q24614596 | ||
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors | Q24617322 | ||
Arachidonic acid and the brain | Q24620380 | ||
DAG lipase activity is necessary for TRP channel regulation in Drosophila photoreceptors | Q24644031 | ||
TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons | Q24644177 | ||
Novel endogenous peptide agonists of cannabinoid receptors | Q24644673 | ||
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol | Q24649418 | ||
Differential sensitivity and mechanism of inhibition of COX-2 oxygenation of arachidonic acid and 2-arachidonoylglycerol by ibuprofen and mefenamic acid | Q24657423 | ||
A biosynthetic pathway for anandamide | Q24671032 | ||
[18F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor | Q24680848 | ||
Hemopressin is an inverse agonist of CB1 cannabinoid receptors | Q24683759 | ||
Understanding synapses: past, present, and future | Q26269897 | ||
Endocannabinoid signaling and long-term synaptic plasticity. | Q35679432 | ||
Persistently active cannabinoid receptors mute a subpopulation of hippocampal interneurons | Q36018163 | ||
Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice | Q36020820 | ||
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors | Q36447081 | ||
Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area. | Q36452302 | ||
Opposing actions of endothelin-1 on glutamatergic transmission onto vasopressin and oxytocin neurons in the supraoptic nucleus | Q36601711 | ||
COX-2 oxidative metabolism of endocannabinoids augments hippocampal synaptic plasticity | Q36677473 | ||
Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain | Q36727266 | ||
Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity | Q36734402 | ||
Homeostatic signaling: the positive side of negative feedback | Q36798818 | ||
Identification of novel endogenous cytochrome p450 arachidonate metabolites with high affinity for cannabinoid receptors | Q36861457 | ||
Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons | Q28144567 | ||
Molecular characterization of a phospholipase D generating anandamide and its congeners | Q28186509 | ||
CB1 cannabinoid receptors and on-demand defense against excitotoxicity | Q28207143 | ||
Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells | Q28212245 | ||
Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor | Q28218654 | ||
Structure of a cannabinoid receptor and functional expression of the cloned cDNA | Q28240076 | ||
A second endogenous cannabinoid that modulates long-term potentiation | Q28248073 | ||
Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling | Q28253698 | ||
Identification and functional characterization of brainstem cannabinoid CB2 receptors | Q28276972 | ||
Presynaptic monoacylglycerol lipase activity determines basal endocannabinoid tone and terminates retrograde endocannabinoid signaling in the hippocampus | Q28286042 | ||
2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain | Q28290395 | ||
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors | Q28292914 | ||
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides | Q28295481 | ||
Molecular characterization of a peripheral receptor for cannabinoids | Q28298338 | ||
International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂ | Q28298445 | ||
Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice | Q28469322 | ||
Neuronal protease-activated receptor 1 drives synaptic retrograde signaling mediated by the endocannabinoid 2-arachidonoylglycerol | Q28511266 | ||
Serotonin 5-HT(2A) receptor activation induces 2-arachidonoylglycerol release through a phospholipase c-dependent mechanism | Q28571959 | ||
Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D | Q28581971 | ||
Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1 | Q28582069 | ||
The CB1 cannabinoid receptor is the major cannabinoid receptor at excitatory presynaptic sites in the hippocampus and cerebellum | Q28587112 | ||
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system | Q28590486 | ||
Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice | Q28591248 | ||
mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis | Q28591542 | ||
Phospholipase C isozymes selectively couple to specific neurotransmitter receptors | Q28593039 | ||
The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission | Q28594648 | ||
Isolation and structure of a brain constituent that binds to the cannabinoid receptor | Q29547476 | ||
Determination and characterization of a cannabinoid receptor in rat brain | Q29618888 | ||
Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation | Q30478061 | ||
Altered surface trafficking of presynaptic cannabinoid type 1 receptor in and out synaptic terminals parallels receptor desensitization | Q30484615 | ||
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. | Q30492114 | ||
Endocannabinoid-dependent homeostatic regulation of inhibitory synapses by miniature excitatory synaptic activities. | Q30492857 | ||
Postsynaptic TRPV1 triggers cell type–specific long-term depression in the nucleus accumbens | Q30500199 | ||
Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging | Q30502227 | ||
Complementary synaptic distribution of enzymes responsible for synthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in the human hippocampus | Q36917918 | ||
Activation of GABAA receptors: views from outside the synaptic cleft. | Q37022454 | ||
TRPC3 channels are required for synaptic transmission and motor coordination | Q37099115 | ||
Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia. | Q37216017 | ||
Endocannabinoid signaling as a synaptic circuit breaker in neurological disease | Q37262759 | ||
Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress | Q37276946 | ||
Transmembrane helical domain of the cannabinoid CB1 receptor | Q37282203 | ||
Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors | Q37285069 | ||
Serotonin evokes endocannabinoid release and retrogradely suppresses excitatory synapses | Q37288785 | ||
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain | Q37312874 | ||
Diglyceride lipase: a pathway for arachidonate release from human platelets | Q37336055 | ||
Should peripheral CB(1) cannabinoid receptors be selectively targeted for therapeutic gain? | Q37337607 | ||
Natural products as tools for neuroscience: discovery and development of novel agents to treat drug abuse | Q37355904 | ||
Endocannabinoid-mediated control of synaptic transmission | Q37363621 | ||
Spine microdomains for postsynaptic signaling and plasticity | Q37425885 | ||
Molecular reconstruction of mGluR5a-mediated endocannabinoid signaling cascade in single rat sympathetic neurons. | Q37436040 | ||
Preferential localization of muscarinic M1 receptor on dendritic shaft and spine of cortical pyramidal cells and its anatomical evidence for volume transmission. | Q39753711 | ||
Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus | Q39757955 | ||
Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals. | Q39831177 | ||
Multiple pathways involved in the biosynthesis of anandamide | Q40106992 | ||
A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. | Q40116679 | ||
A molecular basis of analgesic tolerance to cannabinoids. | Q40146609 | ||
Orexin-1 receptor-cannabinoid CB1 receptor heterodimerization results in both ligand-dependent and -independent coordinated alterations of receptor localization and function | Q40224903 | ||
Activation of PAF receptors results in enhanced synthesis of 2-arachidonoylglycerol (2-AG) in immune cells | Q40773784 | ||
Agonist-induced internalization and trafficking of cannabinoid CB1 receptors in hippocampal neurons. | Q40818985 | ||
Synthesis of prostaglandin E2 ethanolamide from anandamide by cyclooxygenase-2. | Q41093128 | ||
Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway | Q41791622 | ||
Postsynaptic spike firing reduces synaptic GABAA responses in hippocampal pyramidal cells | Q41808335 | ||
The endocannabinoid system controls key epileptogenic circuits in the hippocampus | Q42065383 | ||
The endocannabinoid 2-arachidonoylglycerol is responsible for the slow self-inhibition in neocortical interneurons | Q42110966 | ||
Cannabinoid receptors and modulation of cyclic AMP accumulation in the rat brain | Q42479973 | ||
Activation of muscarinic acetylcholine receptors enhances the release of endogenous cannabinoids in the hippocampus. | Q42528169 | ||
Endocannabinoids Potentiate Synaptic Transmission through Stimulation of Astrocytes | Q42870301 | ||
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system | Q42882543 | ||
Good news for CB1 receptors: endogenous agonists are in the right place | Q42986826 | ||
Bimodal control of stimulated food intake by the endocannabinoid system. | Q43169799 | ||
Activation conditions for the induction of metabotropic glutamate receptor-dependent long-term depression in hippocampal CA1 pyramidal cells | Q43182541 | ||
Synaptic activation of kainate receptors gates presynaptic CB(1) signaling at GABAergic synapses | Q43191478 | ||
Spinal antinociceptive effects of cyclooxygenase inhibition during inflammation: Involvement of prostaglandins and endocannabinoids | Q43251476 | ||
Blockade of effects of smoked marijuana by the CB1-selective cannabinoid receptor antagonist SR141716. | Q43570628 | ||
Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals | Q43574291 | ||
Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors | Q43715218 | ||
Oxygenation of the endocannabinoid, 2-arachidonylglycerol, to glyceryl prostaglandins by cyclooxygenase-2. | Q30606134 | ||
Drug discovery and natural products: end of an era or an endless frontier? | Q30866998 | ||
Concurrent stimulation of cannabinoid CB1 and dopamine D2 receptors enhances heterodimer formation: a mechanism for receptor cross-talk? | Q33211909 | ||
Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex | Q33293523 | ||
The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system | Q33323392 | ||
Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization. | Q33716248 | ||
Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors | Q33717685 | ||
Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticity | Q33744346 | ||
AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitoxicity | Q33784846 | ||
Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses | Q33814760 | ||
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses | Q33940688 | ||
Distinct endocannabinoid control of GABA release at perisomatic and dendritic synapses in the hippocampus | Q33996513 | ||
Nutritional omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions. | Q34025536 | ||
Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens | Q34032832 | ||
Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes | Q34048105 | ||
An endogenous cannabinoid (2-AG) is neuroprotective after brain injury | Q34093755 | ||
Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers | Q34199610 | ||
Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice | Q34203193 | ||
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis | Q34234907 | ||
An endocannabinoid mechanism for stress-induced analgesia. | Q34428429 | ||
Chemical constituents of marijuana: the complex mixture of natural cannabinoids | Q34455944 | ||
Spine Ca2+ signaling in spike-timing-dependent plasticity. | Q34576681 | ||
Unique inhibitory synapse with particularly rich endocannabinoid signaling machinery on pyramidal neurons in basal amygdaloid nucleus | Q34582789 | ||
Neuronal localization of cannabinoid receptors in the basal ganglia of the rat. | Q34602111 | ||
TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus. | Q34684362 | ||
Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. | Q34691517 | ||
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system | Q34745063 | ||
Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver | Q34794697 | ||
Diacylglycerol lipase-alpha and -beta control neurite outgrowth in neuro-2a cells through distinct molecular mechanisms | Q35080503 | ||
Cell-type-specific CCK2 receptor signaling underlies the cholecystokinin-mediated selective excitation of hippocampal parvalbumin-positive fast-spiking basket cells | Q35172234 | ||
Molecular composition of the endocannabinoid system at glutamatergic synapses. | Q35220762 | ||
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes | Q35592076 | ||
COX-2 and fatty acid amide hydrolase can regulate the time course of depolarization-induced suppression of excitation | Q35593070 | ||
Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism. | Q35678770 | ||
Evidence for presynaptic cannabinoid CB(1) receptor-mediated inhibition of noradrenaline release in the guinea pig lung | Q43812206 | ||
Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus. | Q43816494 | ||
Postsynaptic endocannabinoid release is critical to long-term depression in the striatum | Q43971441 | ||
2-Arachidonoyl-sn-glycero-3-phosphate, an arachidonic acid-containing lysophosphatidic acid: occurrence and rapid enzymatic conversion to 2-arachidonoyl-sn-glycerol, a cannabinoid receptor ligand, in rat brain | Q44018878 | ||
The endogenous cannabinoid system controls extinction of aversive memories | Q44085607 | ||
Heterosynaptic LTD of hippocampal GABAergic synapses: a novel role of endocannabinoids in regulating excitability | Q44437517 | ||
n-3 Polyunsaturated fatty acid (PUFA) deficiency elevates and n-3 PUFA enrichment reduces brain 2-arachidonoylglycerol level in mice | Q44524041 | ||
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels | Q44524443 | ||
Neocortical LTD via coincident activation of presynaptic NMDA and cannabinoid receptors | Q44553567 | ||
Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents | Q44758240 | ||
Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus | Q44927481 | ||
Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala. | Q44963304 | ||
The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice | Q45087565 | ||
The wake-promoting peptide orexin-B inhibits glutamatergic transmission to dorsal raphe nucleus serotonin neurons through retrograde endocannabinoid signaling. | Q45240196 | ||
U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevance. | Q45253911 | ||
Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo | Q45299326 | ||
Postsynaptic origin of CB1-dependent tonic inhibition of GABA release at cholecystokinin-positive basket cell to pyramidal cell synapses in the CA1 region of the rat hippocampus. | Q46055962 | ||
Predominant expression of phospholipase Cbeta1 in telencephalic principal neurons and cerebellar interneurons, and its close association with related signaling molecules in somatodendritic neuronal elements | Q46273270 | ||
Requirement for CB1 but not GABAB receptors in the cholecystokinin mediated inhibition of GABA release from cholecystokinin expressing basket cells | Q46366299 | ||
Presynaptic, activity-dependent modulation of cannabinoid type 1 receptor-mediated inhibition of GABA release. | Q46366644 | ||
Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. | Q46624652 | ||
Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus. | Q46691853 | ||
Differential regulation of synaptic inputs by constitutively released endocannabinoids and exogenous cannabinoids. | Q46764070 | ||
Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells | Q47681459 | ||
Lysophosphoinositide-specific phospholipase C in rat brain synaptic plasma membranes | Q48146427 | ||
Subcellular arrangement of molecules for 2-arachidonoyl-glycerol-mediated retrograde signaling and its physiological contribution to synaptic modulation in the striatum. | Q48217036 | ||
Afferent-specific innervation of two distinct AMPA receptor subtypes on single hippocampal interneurons | Q48240092 | ||
Retrograde regulation of GABA transmission by the tonic release of oxytocin and endocannabinoids governs postsynaptic firing. | Q48279730 | ||
Localization of diacylglycerol lipase-alpha around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonoyl-glycerol, and presynaptic cannabinoid CB1 receptor. | Q48556515 | ||
Distinct domains of the CB1 cannabinoid receptor mediate desensitization and internalization | Q48918978 | ||
Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex | Q48971057 | ||
Phospholipase Cbeta serves as a coincidence detector through its Ca2+ dependency for triggering retrograde endocannabinoid signal | Q49124925 | ||
GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus. | Q52023779 | ||
Blockade of central cyclooxygenase (COX) pathways enhances the cannabinoid-induced antinociceptive effects on inflammatory temporomandibular joint (TMJ) nociception. | Q53577374 | ||
Glycine potentiates the NMDA response in cultured mouse brain neurons | Q59050531 | ||
Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus | Q59081310 | ||
Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells | Q61479730 | ||
A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain | Q64212085 | ||
The absolute configuration of δ1-tetrahydrocannabinol, the major active constituent of hashish | Q72255583 | ||
In vivo activation of endocannabinoid system in temporal lobe epilepsy with hippocampal sclerosis | Q83389390 | ||
Endogenously generated 2-arachidonoylglycerol plays an inhibitory role in bombesin-induced activation of central adrenomedullary outflow in rats | Q83523096 | ||
Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus | Q84197041 | ||
Chemical basis of hashish activity | Q93803717 | ||
P921 | main subject | endocannabinoids | Q10483908 |
P304 | page(s) | 529-558 | |
P577 | publication date | 2012-04-17 | |
P1433 | published in | Annual Review of Neuroscience | Q15753632 |
P1476 | title | Multiple functions of endocannabinoid signaling in the brain | |
P478 | volume | 35 |