The TLX1 oncogene drives aneuploidy in T cell transformation

scientific article

The TLX1 oncogene drives aneuploidy in T cell transformation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NM.2246
P932PMC publication ID2974790
P698PubMed publication ID20972433
P5875ResearchGate publication ID47535213

P50authorPier Paolo PandolfiQ7191735
Carlos Cordon-CardoQ11912384
Dietmar J KappesQ90650327
Peter H. WiernikQ100309276
Teresa PalomeroQ114336626
Adolfo A FerrandoQ114336627
Michael HadlerQ125259915
Joni Van der MeulenQ125259998
Andrea CalifanoQ29053203
Hélène CavéQ30170076
Pieter Van VlierbergheQ40204929
Pedro RealQ43160105
Kim De KeersmaeckerQ43188771
Valeria ToselloQ47504357
Xavier SoléQ56285828
Jules P MeijerinkQ57006177
Elisabeth PaiettaQ69071275
Frank SpelemanQ86988048
Peter AplanQ89272233
P2093author name stringJacob M Rowe
Janis Racevskis
Barbara L Kee
Giusy Della Gatta
Susana Raimondi
Kelly Barnes
Fotini Gounari
Nicole Dastugue
Jean Soulier
Maria Luisa Sulis
Mireia Castillo
Jack Lenz
Michelle Kelliher
David Avran
Howard Petrie
P2860cites workModel-based analysis of oligonucleotide arrays: expression index computation and outlier detectionQ27860727
Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell LeukemiaQ28245189
Dysregulated expression of mitotic regulators is associated with B-cell lymphomagenesis in HOX11-transgenic miceQ28291301
HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpointQ28302213
BCL11B is required for positive selection and survival of double-positive thymocytesQ28590236
Bcl11b is required for differentiation and survival of αβ T lymphocytesQ28592191
PHF6 mutations in T-cell acute lymphoblastic leukemiaQ29394463
GenePattern 2.0Q29614171
Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemiaQ29614269
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemiaQ29614324
A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.Q33182502
t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Français de Cytogénétique Hématologique (GFCH).Q34230063
Developmental regulation of lck gene expression in T lymphocytesQ36229919
The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemiaQ36591345
Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survivalQ36776853
NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL.Q36787487
A model for spontaneous B-lineage lymphomas in IgHmu-HOX11 transgenic mice.Q36802885
Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemiaQ37009642
ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenesQ37034832
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancersQ37272977
WT1 mutations in T-ALLQ37291631
A little CIN may cost a lot: revisiting aneuploidy and cancerQ37386176
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemiaQ38287709
Haploinsufficiency of Bcl11b for suppression of lymphomagenesis and thymocyte developmentQ38304625
Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase.Q38338088
Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.Q40195204
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemiaQ40516555
Alterations of the p53, p21, p16, p15 and RAS genes in childhood T-cell acute lymphoblastic leukemiaQ40968306
Comparative gene marker selection suiteQ48446590
Prognostic importance of TLX1 (HOX11) oncogene expression in adults with T-cell acute lymphoblastic leukaemia.Q51027367
Expression of HOX11 in childhood T-lineage acute lymphoblastic leukaemia can occur in the absence of cytogenetic aberration at 10q24: a study from the Children's Cancer Group (CCG)Q54773234
VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasiaQ56963014
Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemiasQ72891582
Prognostic and oncogenic relevance of TLX1/HOX11 expression level in T-ALLsQ80564186
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1321-1327
P577publication date2010-10-24
P1433published inNature MedicineQ1633234
P1476titleThe TLX1 oncogene drives aneuploidy in T cell transformation
P478volume16