scholarly article | Q13442814 |
P356 | DOI | 10.1038/NI927 |
P953 | full work available at URL | http://www.nature.com/articles/ni927 |
http://www.nature.com/articles/ni927.pdf | ||
P3181 | OpenCitations bibliographic resource ID | 3702373 |
P698 | PubMed publication ID | 12717433 |
P5875 | ResearchGate publication ID | 10786008 |
P50 | author | Yukio Mishima | Q109286683 |
P2093 | author name string | Shinichi Aizawa | |
Takashi Yamamoto | |||
Hisami Watanabe | |||
Jiro Hitomi | |||
Jun Inoue | |||
Naoki Takeda | |||
Masanori Utsuyama | |||
Jun Sakata | |||
Ohtsura Niwa | |||
Ryo Kominami | |||
Yuichi Wakabayashi | |||
P2860 | cites work | Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 | Q22010683 |
Profound block in thymocyte development in mice lacking p56lck | Q24298882 | ||
COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein | Q24534913 | ||
Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product | Q24554237 | ||
Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors | Q24650527 | ||
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
Cell kinetic study of normal human bone marrow hematopoiesis and acute leukemia using 7AAD/PY | Q28145070 | ||
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis | Q28189945 | ||
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes | Q28203083 | ||
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest | Q28258615 | ||
Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas | Q28508746 | ||
Bcl11a is essential for normal lymphoid development | Q28511014 | ||
Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice | Q28513839 | ||
Defective T cell development and function in calcineurin A beta -deficient mice | Q28592115 | ||
RB-dependent S-phase response to DNA damage | Q28609381 | ||
Induction of apoptosis in fibroblasts by c-myc protein | Q29614346 | ||
Effects of an Rb mutation in the mouse | Q29619196 | ||
A nonredundant role for the adapter protein Shc in thymic T cell development | Q30309610 | ||
Pleiotropic changes controlled by the pre-T-cell receptor | Q33632421 | ||
The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages | Q33888549 | ||
Homologous recombination at c-fyn locus of mouse embryonic stem cells with use of diphtheria toxin A-fragment gene in negative selection | Q33927120 | ||
Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck | Q33938602 | ||
The BCL11 gene family: involvement of BCL11A in lymphoid malignancies | Q34102839 | ||
Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. | Q34223352 | ||
Bclx regulates the survival of double-positive thymocytes | Q34261390 | ||
WNT signaling and lymphocyte development | Q34619783 | ||
T cell-specific FADD-deficient mice: FADD is required for early T cell development | Q35940897 | ||
p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement. | Q36366527 | ||
c-kit+ stem cells and thymocyte precursors in the livers of adult mice | Q36367212 | ||
FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor | Q40387215 | ||
Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements | Q41039729 | ||
Natural and engineered disorders of lymphocyte development | Q41735894 | ||
Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene. | Q41767340 | ||
Early thymocyte development is regulated by modulation of E2A protein activity | Q41828914 | ||
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages | Q44151375 | ||
Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development. | Q52130337 | ||
A role for histone acetylation in the developmental regulation of VDJ recombination. | Q52171595 | ||
An activated lck transgene promotes thymocyte development in RAG-1 mutant mice. | Q52511681 | ||
Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells | Q59070257 | ||
Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT | Q73808221 | ||
The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival | Q74286666 | ||
A matter of life and cell death | Q77164675 | ||
Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells | Q78093548 | ||
Allelic loss mapping and physical delineation of a region harboring a putative thymic lymphoma suppressor gene on mouse chromosome 12 | Q78093588 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | immunology | Q101929 |
lymphocyte | Q715347 | ||
B cell leukemia/lymphoma 11B | Q21982776 | ||
P304 | page(s) | 533–539 | |
P577 | publication date | 2003-04-28 | |
2003-06-01 | |||
P1433 | published in | Nature Immunology | Q1071725 |
P1476 | title | Bcl11b is required for differentiation and survival of alphabeta T lymphocytes | |
Bcl11b is required for differentiation and survival of αβ T lymphocytes | |||
P478 | volume | 4 |
Q58478657 | A Guardian of T Cell Fate |
Q34187231 | A New Avenue to Cure Cancer by Turning Adaptive Immune T Cells to Innate Immune NK Cells via Reprogramming |
Q91853918 | A de novo substitution in BCL11B leads to loss of interaction with transcriptional complexes and craniosynostosis |
Q30465746 | A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis |
Q46215182 | AML1/RUNX1 gene point mutations in childhood myeloid malignancies |
Q43207231 | ATM deficiency: revealing the pathways to cancer. |
Q39150709 | Aberrant expression of BCL11B in mycosis fungoides and its potential role in interferon-induced apoptosis |
Q58481810 | Acute Lymphoblastic Leukemia |
Q33855540 | Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses |
Q58481759 | Acute lymphoblastic leukemia |
Q42227980 | An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b |
Q51905187 | An essential developmental checkpoint for production of the T cell lineage. |
Q30787663 | Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment |
Q24650585 | BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression |
Q37091336 | BCL11B enhances TCR/CD28-triggered NF-kappaB activation through up-regulation of Cot kinase gene expression in T-lymphocytes |
Q42018674 | BCL11B expression in intramembranous osteogenesis during murine craniofacial suture development |
Q34441819 | BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter |
Q47244851 | BCL11B gene heterozygosity causes weight loss accompanied by increased energy consumption, but not defective adipogenesis, in mice |
Q37088793 | BCL11B is a general transcriptional repressor of the HIV-1 long terminal repeat in T lymphocytes through recruitment of the NuRD complex |
Q28590236 | BCL11B is required for positive selection and survival of double-positive thymocytes |
Q34635079 | BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma |
Q60709804 | BCL11B mutations in patients affected by a neurodevelopmental disorder with reduced type 2 innate lymphoid cells |
Q24294962 | BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes |
Q41788445 | BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor |
Q39241720 | BCL11B suppression does not influence CD34(+) cell differentiation and proliferation |
Q73451255 | Bcl11: sibling rivalry in lymphoid development |
Q64907256 | Bcl11b Regulates IL-17 Through the TGF-β/Smad Pathway in HDM-Induced Asthma. |
Q38892480 | Bcl11b SWI/SNF-complex subunit modulates intestinal adenoma and regeneration after γ-irradiation through Wnt/β-catenin pathway |
Q30855603 | Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network |
Q35671246 | Bcl11b is essential for group 2 innate lymphoid cell development |
Q52560201 | Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma. |
Q33302970 | Bcl11b mutations identified in murine lymphomas increase the proliferation rate of hematopoietic progenitor cells |
Q92924396 | Bcl11b prevents fatal autoimmunity by promoting Treg cell program and constraining innate lineages in Treg cells |
Q48447959 | Bcl11b prevents the intrathymic development of innate CD8 T cells in a cell intrinsic manner. |
Q41763674 | Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes |
Q58097749 | Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16 |
Q52364066 | Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation. |
Q28512050 | Bcl11b/Ctip2 controls the differentiation of vomeronasal sensory neurons in mice |
Q42494508 | Bcl11b/Ctip2 is required for development of lingual papillae in mice |
Q34144149 | CD1d-unrestricted NKT cells are endowed with a hybrid function far superior than that of iNKT cells |
Q39468008 | CTCF and cohesin cooperatively mediate the cell-type specific interchromatin interaction between Bcl11b and Arhgap6 loci |
Q33642286 | CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis |
Q24646255 | CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene |
Q30862469 | CTIP2 expression in human head and neck squamous cell carcinoma is linked to poorly differentiated tumor status |
Q26851400 | CTIP2, a multifunctional protein: cellular physiopathology and therapeutic implications |
Q34148512 | Cancer biology and NuRD: a multifaceted chromatin remodelling complex |
Q45334161 | Cell of origin in radiation-induced premalignant thymocytes with differentiation capability in mice conditionally losing one Bcl11b allele |
Q35085275 | Cell type-specific DNA methylation at intragenic CpG islands in the immune system. |
Q39717449 | Complex interplays in immune T-cell differentiation and developmental fate determination |
Q59354829 | Comprehensive Transcriptome Analysis Reveals Competing Endogenous RNA Networks During Avian Leukosis Virus, Subgroup J-Induced Tumorigenesis in Chickens |
Q30417770 | Coordinated regulation of transcription factor Bcl11b activity in thymocytes by the mitogen-activated protein kinase (MAPK) pathways and protein sumoylation |
Q47290416 | Corrected and Republished from: BCL11A Is a Critical Component of a Transcriptional Network That Activates RAG Expression and V(D)J Recombination |
Q35237502 | Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease |
Q27319539 | Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers |
Q28593246 | Ctip2 controls the differentiation of medium spiny neurons and the establishment of the cellular architecture of the striatum |
Q24656528 | Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis |
Q36073436 | Decision checkpoints in the thymus |
Q38253721 | Demystifying the secret mission of enhancers: linking distal regulatory elements to target genes |
Q48117209 | Depletion of B cell CLL/Lymphoma 11B Gene Expression Represses Glioma Cell Growth |
Q48221433 | Development and differentiation of early innate lymphoid progenitors |
Q38233767 | Developmental gene networks: a triathlon on the course to T cell identity |
Q52690497 | Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch. |
Q34387780 | Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL. |
Q37410601 | Diverting T helper cell trafficking through increased plasticity attenuates autoimmune encephalomyelitis. |
Q28510729 | Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes |
Q33960952 | Down regulation of BCL11B expression inhibits proliferation and induces apoptosis in malignant T cells by BCL11B-935-siRNA. |
Q37271878 | Dual nature of the adaptive immune system in lampreys |
Q28593436 | Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation |
Q37772343 | Eliciting the T cell fate with Notch |
Q39946860 | Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus |
Q41827741 | Evolution of two prototypic T cell lineages. |
Q37439106 | Expression of COUP-TF-interacting protein 2 (CTIP2) in human atopic dermatitis and allergic contact dermatitis skin |
Q36117822 | Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood |
Q47162339 | Expression of Master Regulators of T-cell, Helper T-cell and Follicular Helper T-cell Differentiation in Angioimmunoblastic T-cell Lymphoma |
Q30582103 | Fgd5 identifies hematopoietic stem cells in the murine bone marrow |
Q37210735 | Flow Cytometry Analysis of Transcription Factors in T Lymphocytes |
Q38320682 | Forging T-Lymphocyte Identity: Intersecting Networks of Transcriptional Control |
Q37999788 | From murine to human nude/SCID: the thymus, T-cell development and the missing link |
Q21093284 | Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells |
Q33985141 | Gene enrichment profiles reveal T-cell development, differentiation, and lineage-specific transcription factors including ZBTB25 as a novel NF-AT repressor |
Q45952956 | Gene expression profiles during human CD4+ T cell differentiation. |
Q35041552 | Gene expression profiles in BCL11B-siRNA treated malignant T cells |
Q28590221 | Gene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte development |
Q33620074 | Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus infections. |
Q33835336 | Gga-miR-219b targeting BCL11B suppresses proliferation, migration and invasion of Marek's disease tumor cell MSB1 |
Q33687971 | Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection |
Q26822390 | HEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticity |
Q37734357 | HMGA1 recruits CTIP2-repressed P-TEFb to the HIV-1 and cellular target promoters |
Q42403664 | Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas |
Q38810887 | Hematopoiesis and T-cell specification as a model developmental system |
Q90290778 | Human NK Cell Development: One Road or Many? |
Q35538474 | Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells |
Q41007322 | Identification of BCL11B as a regulator of adipogenesis |
Q35881724 | Illegitimate V(D)J recombination involving nonantigen receptor loci in lymphoid malignancy |
Q33821742 | Illegitimate V(D)J recombination-mediated deletions in Notch1 and Bcl11b are not sufficient for extensive clonal expansion and show minimal age or sex bias in frequency or junctional processing |
Q33686984 | Increased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation |
Q47409193 | Induction of Bcl11b during T cell commitment through a tripartite mechanism |
Q40195158 | Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells |
Q39163676 | Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations |
Q37689391 | Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential. |
Q24650557 | Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression |
Q34609906 | Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication stress and damages |
Q37039580 | Launching the T-cell-lineage developmental programme |
Q33569852 | Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function |
Q41816582 | Lineage determination in the immune system |
Q35282150 | Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function. |
Q24648543 | MicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery components |
Q37299851 | Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development |
Q79838758 | Multi-step lymphomagenesis deduced from DNA changes in thymic lymphomas and atrophic thymuses at various times after gamma-irradiation |
Q37802424 | Multilayered specification of the T-cell lineage fate |
Q30414780 | Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain |
Q35808496 | PHF6 Degrees of Separation: The Multifaceted Roles of a Chromatin Adaptor Protein |
Q40097972 | PTPN2 regulates T cell lineage commitment and αβ versus γδ specification. |
Q51031021 | Persistence of effector memory Th1 cells is regulated by Hopx. |
Q38334842 | Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1). |
Q41676561 | Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes. |
Q40821576 | Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria |
Q93085956 | Programming for T-lymphocyte fates: modularity and mechanisms |
Q50194892 | Promoter hypermethylation of BCL11B gene correlates with downregulation of gene transcription in ankylosing spondylitis patients. |
Q37015302 | Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4+ T-Cell Activation |
Q36759660 | RETRACTED: The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination |
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Q39552928 | RasGRP1 and RasGRP3 Are Required for Efficient Generation of Early Thymic Progenitors |
Q36382766 | Recent insights into the signals that control alphabeta/gammadelta-lineage fate. |
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Q36772386 | Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion |
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Q37374977 | Splicing factor TRA2B is required for neural progenitor survival |
Q30385529 | Structure-function integrity of the adult hippocampus depends on the transcription factor Bcl11b/Ctip2. |
Q42008502 | TNF-α-dependent hematopoiesis following Bcl11b deletion in T cells restricts metastatic melanoma |
Q30882980 | Targeted deletion of p73 in mice reveals its role in T cell development and lymphomagenesis |
Q41715977 | Tcrδ translocations that delete the Bcl11b haploinsufficient tumor suppressor gene promote atm-deficient T cell acute lymphoblastic leukemia |
Q35483684 | The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia |
Q44538932 | The D4Mit12 locus on mouse chromosome 4 provides susceptibility to both gamma-ray-induced and N-methyl-N-nitrosourea-induced thymic lymphomas |
Q46262817 | The E-Id Protein Axis Specifies Adaptive Lymphoid Cell Identity and Suppresses Thymic Innate Lymphoid Cell Development. |
Q47332416 | The N-terminal CCHC zinc finger motif mediates homodimerization of the transcription factor BCL11B. |
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Q37802422 | The intrathymic crossroads of T and NK cell differentiation |
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Q36444458 | The role of BCL11B in hematological malignancy |
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Q38291702 | The role of cerebellar genes in pathology of autism and schizophrenia |
Q35671263 | The transcription factor Bcl11b is specifically expressed in group 2 innate lymphoid cells and is essential for their development |
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