The BCL11 gene family: involvement of BCL11A in lymphoid malignancies

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The BCL11 gene family: involvement of BCL11A in lymphoid malignancies is …
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scholarly articleQ13442814

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P356DOI10.1182/BLOOD.V98.12.3413
P698PubMed publication ID11719382

P2093author name stringLiu H
Siebert R
Schlegelberger B
Steinemann D
Dyer MJ
Willis TG
Gesk S
Harder L
Oscier DG
Satterwhite E
Sonoki T
Tucker PW
Nowak R
Price HP
Arriola EL
P2860cites workDistinct types of diffuse large B-cell lymphoma identified by gene expression profilingQ27860529
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)3413-3420
P577publication date2001-12-01
P1433published inBloodQ885070
P1476titleThe BCL11 gene family: involvement of BCL11A in lymphoid malignancies
P478volume98

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cites work (P2860)
Q41083450A Compendium of Chromatin Contact Maps Reveals Spatially Active Regions in the Human Genome.
Q35946229A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology
Q37644812A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis.
Q60345371A comprehensive genetic and histopathologic analysis identifies two subgroups of B-cell malignancies carrying a t(14;19)(q32;q13) or variant BCL3-translocation
Q35739462A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues.
Q29615157A highly efficient recombineering-based method for generating conditional knockout mutations
Q34315758A novel t(6;14)(q25-q27;q32) in acute myelocytic leukemia involves the BCL11B gene.
Q37081986A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene
Q37327614A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.
Q33569262A survey of well conserved families of C2H2 zinc-finger genes in Daphnia
Q36110400A unique cytogenetic abnormality, t(2;7)(p13.1;p21.3), in a Philadelphia-positive chronic myeloid leukemia
Q46215182AML1/RUNX1 gene point mutations in childhood myeloid malignancies
Q37708916Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas.
Q40660936Activation of HOX11L2 by juxtaposition with 3'-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2).
Q42630118Activation-induced cytidine deaminase induces reproducible DNA breaks at many non-Ig Loci in activated B cells
Q38347126Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair
Q35349869An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development
Q40689379An unbalanced translocation involving chromosome 14 is the probable cause for loss of potentially functional rearranged immunoglobulin heavy chain genes in the Epstein-Barr virus-positive Hodgkin's lymphoma-derived cell line L591.
Q45973697Array comparative genomic hybridization identifies genetic regions associated with outcome in aggressive diffuse large B-cell lymphomas.
Q41808692Array comparative genomic hybridization reveals genomic copy number changes associated with outcome in diffuse large B-cell lymphomas
Q35622991B lymphoid neoplasms of mice: characteristics of naturally occurring and engineered diseases and relationships to human disorders
Q37152985BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription
Q97066987BCL11A Is Oncogenic and Predicts Poor Outcomes in Natural Killer/T-Cell Lymphoma
Q91713543BCL11A Promotes the Progression of Laryngeal Squamous Cell Carcinoma
Q90698092BCL11A confers cell invasion and migration in androgen receptor-positive triple-negative breast cancer
Q64054082BCL11A enhances stemness and promotes progression by activating Wnt/β-catenin signaling in breast cancer
Q36964364BCL11A overexpression predicts survival and relapse in non-small cell lung cancer and is modulated by microRNA-30a and gene amplification.
Q24650585BCL11A-dependent recruitment of SIRT1 to a promoter template in mammalian cells results in histone deacetylation and transcriptional repression
Q34441819BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter
Q93164819Bcl11 Transcription Factors Regulate Cortical Development and Function
Q73451255Bcl11: sibling rivalry in lymphoid development
Q24315994Bcl11A/CTIP1 regulates expression of DCC and MAP1b in control of axon branching and dendrite outgrowth
Q41363689Bcl11a Deficiency Leads to Hematopoietic Stem Cell Defects with an Aging-like Phenotype
Q34760844Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo
Q36478284Bcl11a is essential for lymphoid development and negatively regulates p53.
Q28511014Bcl11a is essential for normal lymphoid development
Q28592191Bcl11b is required for differentiation and survival of αβ T lymphocytes
Q33302970Bcl11b mutations identified in murine lymphomas increase the proliferation rate of hematopoietic progenitor cells
Q48447959Bcl11b prevents the intrathymic development of innate CD8 T cells in a cell intrinsic manner.
Q38692964Bcl11b-A Critical Neurodevelopmental Transcription Factor-Roles in Health and Disease.
Q33361902Bcl11b: A New Piece to the Complex Puzzle of Amyotrophic Lateral Sclerosis Neuropathogenesis?
Q24534913COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein
Q33642286CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis
Q30862469CTIP2 expression in human head and neck squamous cell carcinoma is linked to poorly differentiated tumor status
Q34148512Cancer biology and NuRD: a multifaceted chromatin remodelling complex
Q54608168Characterization of a recurrent translocation t(2;3)(p15-22;q26) occurring in acute myeloid leukaemia.
Q53620559Characterization of target genes at the 2p15-16 amplicon in diffuse large B-cell lymphoma.
Q58001012Chromosome 14q32 translocations involving the immunoglobulin heavy chain locus in chronic lymphocytic leukaemia identify a disease subset with poor prognosis
Q33437080Chronic Lymphocytic Leukemia with Translocation (2;14)(p16;q32): A Case Report and Review of the Literature
Q35742367Clinical and biological significance of de novo CD5+ diffuse large B-cell lymphoma in Western countries.
Q92646611Clinical significance of BCL11A expression in ER-negative and PR-negative endometrial carcinoma
Q33864314Combination of BCL11A siRNA with vincristine increases the apoptosis of SUDHL6 cells
Q39105585Comparative analysis of hepatocellular carcinoma and cirrhosis gene expression profiles
Q33935974Contingent gene regulatory networks and B cell fate specification
Q47290416Corrected and Republished from: BCL11A Is a Critical Component of a Transcriptional Network That Activates RAG Expression and V(D)J Recombination
Q27319539Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers
Q35213318Cytogenetic evolution of follicular lymphoma
Q91680524DNA methylation profiling implicates exposure to PCBs in the pathogenesis of B-cell chronic lymphocytic leukemia
Q36800496DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease
Q41921064De novo 2p16.1 microdeletion with metastatic esophageal adenocarcinoma
Q37659927Dendritic cell fate is determined by BCL11A.
Q28273746Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32)
Q34387780Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.
Q37641982Downregulation of BCL11A by siRNA induces apoptosis in B lymphoma cell lines
Q47409251Enforced expression of MIR142, a target of chromosome translocation in human B-cell tumors, results in B-cell depletion
Q92052916Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia
Q64933372Epsilon-Globin HBE1 Enhances Radiotherapy Resistance by Down-Regulating BCL11A in Colorectal Cancer Cells.
Q40537994Epstein-Barr virus is integrated between REL and BCL-11A in American Burkitt lymphoma cell line (NAB-2).
Q30478328Expression of the brain transcription factor OTX1 occurs in a subset of normal germinal-center B cells and in aggressive Non-Hodgkin Lymphoma
Q35909440Expression profiling of uterine leiomyomata cytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional profilingof the t(12;14) and evidence in support of predisposing genetic heterogeneity
Q58700685Functional characterization of TBR1 variants in neurodevelopmental disorder
Q21093284Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells
Q55042257Gains of the proto-oncogene BCL11A and nuclear accumulation of BCL11A(XL) protein are frequent in primary mediastinal B-cell lymphoma.
Q61312181Gains ofREL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL protein
Q45012890Gene expression analysis of plasmablastic lymphoma identifies downregulation of B-cell receptor signaling and additional unique transcriptional programs
Q38973429Gene expression profile analysis of SUDHL6 cells with siRNA-mediated BCL11A downregulation
Q35041552Gene expression profiles in BCL11B-siRNA treated malignant T cells
Q39630988Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion.
Q36287371Genetic polymorphisms and plasma levels of BCL11A contribute to the development of laryngeal squamous cell carcinoma
Q37622580Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer
Q24652468Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of beta-thalassemia
Q93182953Genomic alterations important for the prognosis in patients with follicular lymphoma treated in SWOG study S0016
Q36513564Genomic alterations in Hodgkin's lymphoma
Q26822390HEB in the spotlight: Transcriptional regulation of T-cell specification, commitment, and developmental plasticity
Q33361527Hemoglobin switching's surprise: the versatile transcription factor BCL11A is a master repressor of fetal hemoglobin
Q37298691High expression of MAP7 predicts adverse prognosis in young patients with cytogenetically normal acute myeloid leukemia
Q34161181High incidence of Hox11L2 expression in children with T-ALL.
Q38486378Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2.
Q28508746Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas
Q60921425Identification of key genes and specific pathways potentially involved in androgen-independent, mitoxantrone-resistant prostate cancer
Q48315981Identification of novel BCL11A variants in patients with epileptic encephalopathy: Expanding the phenotypic spectrum.
Q47824801Identification of novel mutations in the HbF repressor gene BCL11A in patients with autism and intelligence disabilities.
Q38441009Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS.
Q36824956Immunoglobulin gene translocations in chronic lymphocytic leukemia: A report of 35 patients and review of the literature
Q34463668Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL
Q54342522Influences of genetic variation on fetal hemoglobin.
Q61312332Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci
Q24650557Involvement of the histone deacetylase SIRT1 in chicken ovalbumin upstream promoter transcription factor (COUP-TF)-interacting protein 2-mediated transcriptional repression
Q34609906Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication stress and damages
Q34126438Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene
Q34469099Low expression of T-cell transcription factor BCL11b predicts inferior survival in adult standard risk T-cell acute lymphoblastic leukemia patients
Q34055169MiR-3960 binding sites with mRNA of human genes
Q34673170MicroRNA-486-3p regulates γ-globin expression in human erythroid cells by directly modulating BCL11A.
Q38484538Molecular cytogenetic detection of chromosomal breakpoints in T-cell receptor gene loci
Q91940302Molecular simulation studies on B-cell lymphoma/leukaemia 11A (BCL11A)
Q36224328Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.
Q36579119Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an International DLBCL rituximab-CHOP Consortium Program Study
Q49513753Predictors of lymphovascular invasion identified from pathological factors in Chinese patients with breast cancer
Q37015302Protein Kinase C-Mediated Phosphorylation of BCL11B at Serine 2 Negatively Regulates Its Interaction with NuRD Complexes during CD4+ T-Cell Activation
Q34342958Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.
Q33244998Proteomics of acute myeloid leukaemia: Cytogenetic risk groups differ specifically in their proteome, interactome and post-translational protein modifications
Q83995851REL-positive double minute chromosomes in follicular lymphoma
Q36759660RETRACTED: The BCL11A transcription factor directly activates RAG gene expression and V(D)J recombination
Q80890208Rapid amplification of immunoglobulin heavy chain switch (IGHS) translocation breakpoints using long-distance inverse PCR
Q34576134Reduced level of the BCL11B protein is associated with adult T-cell leukemia/lymphoma
Q39323710Regulation of prostate cancer immunity-related genes in PC3 prostate cancer cells by ETS-1
Q80731905Remarkable leukemogenic potency and quality of a constitutively active neurotrophin receptor, deltaTrkA
Q35094507Retroviral insertional mutagenesis: tagging cancer pathways
Q27014084Role of the transcription factor Bcl11b in development and lymphomagenesis
Q49910540SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia
Q36605667Somatic stem cells and the origin of cancer
Q40529812Spontaneously immortalized human T lymphocytes develop gain of chromosomal region 2p13-24 as an early and common genetic event.
Q90439002Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome
Q48726361Systematic tracking of dysregulated modules identifies novel genes in cancer
Q36138285The BCL11A-XL expression predicts relapse in squamous cell carcinoma and large cell carcinoma
Q57447372The BCL11AXL transcription factor: its distribution in normal and malignant tissues and use as a marker for plasmacytoid dendritic cells
Q91658641The Unsolved Puzzle of c-Rel in B Cell Lymphoma
Q101403190The bone marrow microenvironment of pre-B acute lymphoblastic leukemia at single-cell resolution
Q28241767The c-Rel transcription factor and B-cell proliferation: a deal with the devil
Q34662848The configuration of the immunoglobulin genes in B cell chronic lymphocytic leukemia
Q50201177The expression pattern of Bcl11a, Mdm2 and Pten genes in B-cell acute lymphoblastic leukemia.
Q24294822The functional interactome landscape of the human histone deacetylase family
Q42944687The gene expression patterns of BMPR2, EP300, TGFβ2, and TNFAIP3 in B-Lymphoma cells
Q91723487The global clonal complexity of the murine blood system declines throughout life and after serial transplantation
Q35140188The pathogenetic role of oncogenes deregulated by chromosomal translocation in B-cell malignancies.
Q36444458The role of BCL11B in hematological malignancy
Q64246815The rs61742690 (S783N) single nucleotide polymorphism is a suitable target for disrupting BCL11A-mediated foetal-to-adult globin switching
Q33301651Three-dimensional culturing of the Hodgkin lymphoma cell-line L1236 induces a HL tissue-like gene expression pattern
Q35610677Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation.
Q27011507Using mouse models to study function of transcriptional factors in T cell development
Q27015808Vitamin D and microRNAs in bone
Q73826929[Genetic changes in chronic lymphocytic leukemia]
Q34163536p53-Dependent transcriptional responses to interleukin-3 signaling

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