The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development.

scientific article

The central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.3408-03.2004
P932PMC publication ID6730001
P698PubMed publication ID14724251
P5875ResearchGate publication ID8466219

P50authorYves JossinQ54901112
P2093author name stringAndré M Goffinet
Joachim Herz
Thomas Hiesberger
Catherine Lambert de Rouvroit
Nina Ignatova
P2860cites workReelin promotes peripheral synapse elimination and maturationQ44534391
Inhibition of Src Family Kinases and Non-Classical Protein Kinases C Induce a Reeler-Like Malformation of Cortical Plate DevelopmentQ44637022
Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler miceQ45713976
A panel of monoclonal antibodies against reelin, the extracellular matrix protein defective in reeler mutant miceQ48222828
The reeler mouse as a model of brain developmentQ48350261
Regulation of Purkinje cell alignment by reelin as revealed with CR-50 antibody.Q48706946
Dab1 tyrosine phosphorylation sites relay positional signals during mouse brain development.Q52165759
Reelin binds alpha3beta1 integrin and inhibits neuronal migration.Q55034150
Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2Q22010158
Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylationQ22010836
Reelin molecules assemble together to form a large protein complex, which is inhibited by the function-blocking CR-50 antibodyQ24675499
Colocalization of integrin receptors and reelin in dendritic spine postsynaptic densities of adult nonhuman primate cortexQ24677027
Proteins of the CNR family are multiple receptors for ReelinQ28141368
Reelin and brain developmentQ28207865
Role of the reelin signaling pathway in central nervous system developmentQ28214353
Aberrant splicing of a mouse disabled homolog, mdab1, in the scrambler mouseQ28248620
Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in miceQ28251984
Neuronal position in the developing brain is regulated by mouse disabled-1Q28251995
Reelin activates SRC family tyrosine kinases in neuronsQ28513455
Platelet-derived growth factor mediates tyrosine phosphorylation of the cytoplasmic domain of the low Density lipoprotein receptor-related protein in caveolaeQ28570390
An LDL-receptor-related protein mediates Wnt signalling in miceQ28588625
A protein related to extracellular matrix proteins deleted in the mouse mutant reelerQ29618965
Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutationsQ33845128
Reelin, the extracellular matrix protein deficient in reeler mutant mice, is processed by a metalloproteinase.Q33857894
Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptorQ33982023
Brain development: integrins and the Reelin pathwayQ34105449
Platelet-derived growth factor (PDGF)-induced tyrosine phosphorylation of the low density lipoprotein receptor-related protein (LRP). Evidence for integrated co-receptor function betwenn LRP and the PDGF.Q34114977
Secreted Reelin molecules form homodimers.Q34140685
Fyn tyrosine kinase is a critical regulator of disabled-1 during brain developmentQ34170326
Differential binding of ligands to the apolipoprotein E receptor 2.Q34219781
The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.Q34310467
Reelin is a secreted glycoprotein recognized by the CR-50 monoclonal antibody.Q34412746
Signalling cascade of CNR cadherins (Reelin receptors) in the mammalian brain.Q34684266
The reelin signaling pathway: some recent developments.Q35134864
Reelin-induced tyrosine [corrected] phosphorylation of disabled 1 during neuronal positioningQ35192054
Disruption of hippocampal development in vivo by CR-50 mAb against reelinQ36304368
The gene encoding disabled-1 (DAB1), the intracellular adaptor of the Reelin pathway, reveals unusual complexity in human and mouseQ38360596
Identification of reelin-induced sites of tyrosyl phosphorylation on disabled 1.Q43560391
Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortexQ43715204
A hypomorphic allele of dab1 reveals regional differences in reelin-Dab1 signaling during brain developmentQ43878497
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectproteolysisQ33123
P304page(s)514-521
P577publication date2004-01-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleThe central fragment of Reelin, generated by proteolytic processing in vivo, is critical to its function during cortical plate development
P478volume24

Reverse relations

cites work (P2860)
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