Distinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides

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Distinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.50.1.324-331.2006
P932PMC publication ID1346820
P698PubMed publication ID16377704

P50authorMira EdgertonQ88247586
P2093author name stringSlavena Vylkova
Xuewei S Li
Jennifer C Berner
P2860cites workCandidacidal activities of human lactoferrin peptides derived from the N terminusQ24290527
Human salivary histatin 5 causes disordered volume regulation and cell cycle arrest in Candida albicansQ24537545
Candida albicans Ssa1/2p is the cell envelope binding protein for human salivary histatin 5Q28205819
A cascade of 24 histatins (histatin 3 fragments) in human saliva. Suggestions for a pre-secretory sequential cleavage pathwayQ28273563
Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistanceQ31136813
Histatin 3-mediated killing of Candida albicans: effect of extracellular salt concentration on binding and internalizationQ33977671
Salivary histatin 5 and human neutrophil defensin 1 kill Candida albicans via shared pathways.Q33980976
Susceptibility of nontypeable Haemophilus influenzae to human beta-defensins is influenced by lipooligosaccharide acylationQ34130303
Rapid membrane permeabilization and inhibition of vital functions of gram-negative bacteria by bactenecinsQ35107874
Fungistatic and fungicidal activity of human parotid salivary histidine-rich polypeptides on Candida albicansQ37085706
Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranesQ37662088
The TRK1 potassium transporter is the critical effector for killing of Candida albicans by the cationic protein, Histatin 5.Q38335411
Human beta-defensins: differential activity against candidal species and regulation by Candida albicansQ40433088
Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganismsQ40638341
Endogenous vertebrate antibiotics. Defensins, protegrins, and other cysteine-rich antimicrobial peptidesQ41307316
Interactions of histatin 5 and histatin 5-derived peptides with liposome membranes: surface effects, translocation and permeabilizationQ42013682
beta-defensin expression in immunocompetent and immunodeficient germ-free and Candida albicans-monoassociated miceQ42467013
Candidacidal activity of salivary histatins. Identification of a histatin 5-binding protein on Candida albicansQ42540712
Defensins from insects and plants interact with fungal glucosylceramidesQ47398270
Delineation of an active fragment and poly(L-proline) II conformation for candidacidal activity of bactenecin 5.Q52519123
Structure-biological activity relationships of 11-residue highly basic peptide segment of bovine lactoferrin.Q52522425
A helical region on human lactoferrin. Its role in antibacterial pathogenesis.Q52532252
Characterization of Histatin 5 with Respect to Amphipathicity, Hydrophobicity, and Effects on Cell and Mitochondrial Membrane Integrity Excludes a Candidacidal Mechanism of Pore FormationQ60314973
The Cellular Target of Histatin 5 onCandida albicansIs the Energized MitochondrionQ60314983
Salivary histatin 5: dependence of sequence, chain length, and helical conformation for candidacidal activityQ68929515
HIV-1 protein Vpr causes gross mitochondrial dysfunction in the yeast Saccharomyces cerevisiaeQ73545330
Salivary histatin 5 induces non-lytic release of ATP from Candida albicans leading to cell deathQ77926810
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectCandida albicansQ310443
P304page(s)324-331
P577publication date2006-01-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleDistinct antifungal mechanisms: beta-defensins require Candida albicans Ssa1 protein, while Trk1p mediates activity of cysteine-free cationic peptides
P478volume50

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