Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain

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Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1989PNAS...86.6758G
P356DOI10.1073/PNAS.86.17.6758
P932PMC publication ID297925
P698PubMed publication ID2505261
P5875ResearchGate publication ID20651403

P2093author name stringW B Anderson
R Gopalakrishna
P2860cites workStudies and perspectives of protein kinase C.Q34162282
Role of insulin receptor phosphorylation in the insulinomimetic effects of hydrogen peroxideQ34367006
Evidence for the involvement of sulfhydryl oxidation in the regulation of fat cell hexose transport by insulinQ35129636
Turnover of bacterial glutamine synthetase: oxidative inactivation precedes proteolysisQ35342066
Competitive inhibition by diacylglycerol of specific phorbol ester bindingQ36248225
Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasisQ37483919
Phorbol diester receptor copurifies with protein kinase CQ37600158
Activation of soluble guanylate cyclase from rat lung by incubation or by hydrogen peroxideQ39127107
Protein kinases 1988: a current perspectiveQ39488279
Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brainQ40106798
Cell division in normal and transformed cells: The possible role of superoxide and hydrogen peroxideQ41550141
Susceptibility of protein kinase C to oxidative inactivation: loss of both phosphotransferase activity and phorbol diester bindingQ41994316
Hydrogen peroxide stimulates tyrosine phosphorylation of the insulin receptor and its tyrosine kinase activity in intact cellsQ42158317
Diminution of mouse epidermal superoxide dismutase and catalase activities by tumor promotersQ42472051
Factors influencing chelator-stable, detergent-extractable, phorbol diester-induced membrane association of protein kinase C. Differences between Ca2+-induced and phorbol ester-stabilized membrane bindings of protein kinase C.Q42809835
Formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Is haemoglobin a biological Fenton reagent?Q42857484
Differential expression of multiple protein kinase C subspecies in rat central nervous tissueQ45095382
Differential distribution of protein kinase C isozymes in the various regions of brainQ48183333
Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetateQ48428081
Rapid purification of calcium-activated protease by calcium-dependent hydrophobic-interaction chromatographyQ48470657
Stimulation of tyrosine-specific protein phosphorylation in the rat liver plasma membrane by oxygen radicalsQ69636459
The effects of chemical modification of calmodulin on Ca2+-induced exposure of a hydrophobic region. Separation of active and inactive forms of calmodulinQ69938508
Binding to erythrocyte membrane is the physiological mechanism for activation of Ca2+-dependent neutral proteinaseQ70082398
A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca2+-Dependent Protein KinaseQ72811344
Modulation of Ca2+-activated, phospholipid-dependent protein kinase in platelets treated with a tumor-promoting phorbol esterQ72819449
Stimulation of human polymorphonuclear leukocyte superoxide anion radical production by tumor promotersQ72897858
P433issue17
P407language of work or nameEnglishQ1860
P1104number of pages5
P304page(s)6758-6762
P577publication date1989-09-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCa2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain
P478volume86

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cites work (P2860)
Q26741122"Oxygen Sensing" by Na,K-ATPase: These Miraculous Thiols
Q410142323-Aminobenzamide inhibition of protein kinase C at a cellular level
Q36662707A direct redox regulation of protein kinase C isoenzymes mediates oxidant-induced neuritogenesis in PC12 cells
Q44614776A novel role of protein kinase C-delta in cell signaling triggered by glutathione depletion.
Q48511497A role for superoxide in protein kinase C activation and induction of long-term potentiation.
Q34845287Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion.
Q35281343Activation of promoter activity of the catalytic subunit of γ-glutamylcysteine ligase (GCL) in brain endothelial cells by insulin requires antioxidant response element 4 and altered glycemic status: implication for GCL expression and GSH synthesis
Q36590164Activation of protein kinase C by tyrosine phosphorylation in response to H2O2.
Q49079404An in vitro promoting role for hydrogen peroxide in human sperm capacitation
Q33541802Antioxidant therapy against cerebral vasospasm following aneurysmal subarachnoid hemorrhage
Q28391506Basic principles and emerging concepts in the redox control of transcription factors
Q42590427Calcium-dependent photodynamic action of di- and tetrasulphonated aluminium phthalocyanine on normal and tumour-derived rat pancreatic exocrine cells
Q41816401Cardioprotective effects of anesthetic preconditioning in rats with ischemia-reperfusion injury: propofol versus isoflurane
Q36778740Cell proliferation, reactive oxygen and cellular glutathione
Q34816510Cell signalling and the glutathione redox system
Q50787090Cellularly generated active oxygen species and HeLa cell proliferation.
Q42159924Characterization of two forms of protein kinase C alpha, with different substrate specificities, from skeletal muscle
Q37171029DNA damage by oxygen-derived species Its mechanism and measurement in mammalian systems
Q68091293Decavanadate acts like an alpha-adrenergic agonist in redistributing protein kinase C activity
Q40202662Diazoxide-induced respiratory inhibition - a putative mitochondrial K(ATP) channel independent mechanism of pharmacological preconditioning
Q44066867Different modes of NF-kappaB/Rel activation in pancreatic lobules
Q41669586Differential distribution of protein phosphatase 2A in human breast carcinoma cell lines and its relation to estrogen receptor status.
Q44535853Dual action of hydrogen peroxide on synaptic transmission at the frog neuromuscular junction
Q44820342EGF-Receptor phosphorylation and signaling are targeted by H2O2 redox stress
Q36702384Electron and proton transport across the plasma membrane
Q43641253Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism
Q77322522Ethanol-induced effects on expression level, activity, and distribution of protein kinase C isoforms in rat liver Golgi apparatus
Q37350706Evidence for an essential role of reactive oxygen species in the genesis of late preconditioning against myocardial stunning in conscious pigs
Q49923465Evolving Mechanisms of Vascular Smooth Muscle Contraction Highlight Key Targets in Vascular Disease
Q51377507Flumazenil preconditions cardiomyocytes via oxygen radicals and K(ATP) channels.
Q43512223Glutathione depletion induces apoptosis of rat hepatocytes through activation of protein kinase C novel isoforms and dependent increase in AP-1 nuclear binding
Q36967326Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) phosphorylation by protein kinase Cδ (PKCδ) inhibits mitochondria elimination by lysosomal-like structures following ischemia and reoxygenation-induced injury
Q41833977Green tea polyphenols precondition against cell death induced by oxygen-glucose deprivation via stimulation of laminin receptor, generation of reactive oxygen species, and activation of protein kinase Cε.
Q73405511H(2)O(2) activity on platelet adhesion to fibrinogen and protein tyrosine phosphorylation
Q43917359H(2)O(2) opens mitochondrial K(ATP) channels and inhibits GABA receptors via protein kinase C-epsilon in cardiomyocytes
Q41019400Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase
Q40853498Hydrogen peroxide attenuates store-operated calcium entry and enhances calcium extrusion in thyroid FRTL-5 cells
Q28566012Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2
Q51842518Hydrogen peroxide inhibits cell cycle progression by inhibition of the spreading of mitotic CHO cells.
Q40405835Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C.
Q42201370Hyperoxia, unlike phorbol ester, induces glutathione peroxidase through a protein kinase C-independent mechanism
Q30812494Identification of oxidative stress-regulated genes in rat aortic smooth muscle cells by suppression subtractive hybridization
Q88797989Imbalance in Protein Thiol Redox Regulation and Cancer-Preventive Efficacy of Selenium
Q42799858Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol
Q39455174Inhibition of long-term potentiation by CuZn superoxide dismutase injection in rat dentate gyrus: involvement of muscarinic M1 receptor
Q40934232Insulin signaling is inhibited by micromolar concentrations of H(2)O(2). Evidence for a role of H(2)O(2) in tumor necrosis factor alpha-mediated insulin resistance
Q23918464Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway
Q51543526Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes.
Q30435292Isoflurane induces a postconditioning effect on bovine pulmonary arterial endothelial cells exposed to oxygen-glucose deprivation
Q30429156Isoflurane preconditioning increases endothelial cell tolerance to in-vitro simulated ischaemia
Q48314499Lipid peroxides in the free radical pathophysiology of brain diseases
Q34257440Local regulation of arterial L-type calcium channels by reactive oxygen species.
Q35676885Locally generated methylseleninic acid induces specific inactivation of protein kinase C isoenzymes: relevance to selenium-induced apoptosis in prostate cancer cells
Q45182908Location and functional significance of retinol-binding sites on the serine/threonine kinase, c-Raf
Q53389923Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model.
Q77313307Mechanisms of inactivation of hepatocyte protein kinase C isoforms following acute ethanol treatment
Q38198449Mitochondrial reactive oxygen species production and elimination
Q33770814Monograph: reassessment of human cancer risk of aldrin/dieldrin
Q74482550Nitric oxide mediates protein kinase C isoform translocation in rat heart during postischemic reperfusion
Q28594421Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase
Q37347008Oxidant stress and carcinogenesis
Q47863964Oxidant stress with hydrogen peroxide attenuates calcium paradox injury: role of protein kinase C and ATP-sensitive potassium channel
Q41389726Oxidant-induced activation of protein kinase C in UC11MG cells
Q41260199Oxidants as stimulators of signal transduction
Q33624234Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling
Q73024305Oxidative modulation of cyclic AMP-dependent protein kinase in human fibroblasts: possible role in psoriasis
Q37658133Oxidative stress and oxidative damage in carcinogenesis
Q28083707Oxidative stress as activators of sensory nerves for cough
Q33655444PKC expression is regulated by dietary K intake and mediates internalization of SK channels in the CCD.
Q28477084PKCδ sensitizes neuroblastoma cells to L-buthionine-sulfoximine and etoposide inducing reactive oxygen species overproduction and DNA damage
Q64983755Paradoxical effect of reagents for sulfhydryl and disulfide groups on human sperm capacitation and superoxide production.
Q54110304Pharmacological inhibition of the mitochondrial NADPH oxidase 4/PKCα/Gal-3 pathway reduces left ventricular fibrosis following myocardial infarction.
Q37257282Phosphorylated extracellular signal-regulated protein kinases 1 and 2 phosphorylate Sp1 on serine 59 and regulate cellular senescence via transcription of p21Sdi1/Cip1/Waf1.
Q43640310Preconditioning attenuates apoptosis and necrosis: role of protein kinase C epsilon and -delta isoforms
Q33972677Preconditioning the Myocardium: From Cellular Physiology to Clinical Cardiology
Q47131231Protein Kinase C as Regulator of Vascular Smooth Muscle Function and Potential Target in Vascular Disorders
Q38969623Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification.
Q37423295Protein kinase C inhibitors prevent induction and continued expression of cell memory in Hermissenda type B photoreceptors
Q38345935Protein kinase C isoenzymes in airway smooth muscle
Q33992775Protein kinase C isoenzymes: a review of their structure, regulation and role in regulating airways smooth muscle tone and mitogenesis
Q42831341Protein kinase C phosphorylation of rat liver S-adenosylmethionine synthetase: dissociation and production of an active monomer
Q33989848Protein kinase C signaling and oxidative stress
Q41971372Protein kinase C: an attractive target for cancer therapy.
Q44185576ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel
Q40452410Reactive cysteine in the structural Zn(2+) site of the C1B domain from PKCα.
Q38196174Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathology
Q46384311Reactive oxygen species and protein kinases modulate the level of phospho-MEK-like proteins during human sperm capacitation
Q37097685Reactive oxygen species and respiratory plasticity following intermittent hypoxia.
Q37739212Reactive oxygen species in early and delayed cardiac adaptation
Q28396273Reactive oxygen species in inflammation and tissue injury
Q48129089Reactive oxygen species mediate activity-dependent neuron-glia signaling in output fibers of the hippocampus
Q42218987Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload.
Q57464810Reconstitution of protein kinase C-induced contractile Ca2+ sensitization in triton X-100-demembranated rabbit arterial smooth muscle
Q26740191Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy
Q27004547Redox balance dynamically regulates vascular growth and remodeling
Q44648822Redox control of changes in protein sulfhydryl levels during human sperm capacitation
Q40958774Redox modulation of intracellular free calcium concentration in thyroid FRTL-5 cells: evidence for an enhanced extrusion of calcium
Q42109141Redox regulation of cardiac protein kinase C
Q33595625Redox regulation of cellular signalling
Q35819835Redox regulation of mammalian sperm capacitation
Q38035382Redox regulation of sodium and calcium handling
Q39174495Redox regulation of the actin cytoskeleton and its role in the vascular system
Q37446110Redox signaling in cardiovascular health and disease.
Q36460627Redox signaling pathways involved in neuronal ischemic preconditioning
Q38890566Redox signaling: An evolution from free radicals to aging
Q38190300Redox-mediated signal transduction by cardiovascular Nox NADPH oxidases.
Q36666637Regulation of smooth muscle by inducible nitric oxide synthase and NADPH oxidase in vascular proliferative diseases
Q39939488Remote ischaemic preconditioning shortens QT intervals during exercise in healthy subjects
Q36462042Role of Subplasmalemmal Mitochondria in Angiotensin II-Mediated Contraction
Q43640271Role of nitric oxide and protein kinase C in ACh-induced cardioprotection
Q41599095Role of phosphoinositide 3-kinase {alpha}, protein kinase C, and L-type Ca2+ channels in mediating the complex actions of angiotensin II on mouse cardiac contractility
Q38789318Role of reactive oxygen species and TRP channels in the cough reflex
Q44620928Roles of Superoxide, Peroxynitrite, and Protein Kinase C in the Development of Tolerance to Nitroglycerin
Q30912462Scanning electrochemical microscopy of living cells: different redox activities of nonmetastatic and metastatic human breast cells
Q36101833Scanning electrochemical microscopy: detection of human breast cancer cells by redox environment
Q33584619Sensory nerve terminal mitochondrial dysfunction induces hyperexcitability in airway nociceptors via protein kinase C
Q42804533Sequential modification of serines 621 and 624 in the Raf-1 carboxyl terminus produces alterations in its electrophoretic mobility.
Q31940626Signal transduction of flumazenil-induced preconditioning in myocytes
Q34307275Signalling apoptosis: a radical approach.
Q28391160Spatiotemporal regulation of Src and its substrates at invadosomes
Q72370936Stimulation of NADPH-dependent reactive oxygen species formation and DNA damage by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat peritoneal lavage cells
Q41972833Stimulation of arterial smooth muscle L-type calcium channels by hydrogen peroxide requires protein kinase C.
Q72036022Superoxide anion production by human spermatozoa as a part of the ionophore‐induced acrosome reaction process
Q45981272The alveolar macrophage as a model of calcium signaling in oxidative stress.
Q37771597The cell biology of ischemic renal injury
Q36368891The cysteine-rich regions of the regulatory domains of Raf and protein kinase C as retinoid receptors
Q42480123The effect of active oxygen generated by xanthine/xanthine oxidase on genes and signal transduction in mouse epidermal JB6 cells
Q37610009The exercising heart at altitude.
Q30478263The fundamental organization of cardiac mitochondria as a network of coupled oscillators
Q46195510The influence of diet on protein oxidation
Q42553382The mitogenic effect of H2O2 for vascular smooth muscle cells is mediated by an increase of the affinity of basic fibroblast growth factor for its receptor
Q28290101The nitric oxide hypothesis of late preconditioning
Q24670939The noble gas xenon induces pharmacological preconditioning in the rat heart in vivo via induction of PKC-epsilon and p38 MAPK
Q74293279The role of the phosphoinositide signalling system in the pathogenesis of sporadic Alzheimer's disease: a hypothesis
Q35969287Tobacco smoke tumor promoters, catechol and hydroquinone, induce oxidative regulation of protein kinase C and influence invasion and metastasis of lung carcinoma cells
Q40953044Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis
Q41070814Transmembrane redox signaling activates NF-kappaB in macrophages
Q42437003UV irradiation increases ROS production via PKCdelta signaling in primary murine fibroblasts
Q53795722UVB radiation exposes fibrinogen binding sites on platelets by activating protein kinase C via reactive oxygen species.
Q52569094Urate synthesis in the blood-sucking insect rhodnius prolixus. Stimulation by hemin is mediated by protein kinase C.
Q89063384VCAM-1 induces signals that stimulate ZO-1 serine phosphorylation and reduces ZO-1 localization at lung endothelial cell junctions
Q37263935VCAM-1 signals activate endothelial cell protein kinase Calpha via oxidation
Q42155786Various Molecular Species of Diacylglycerol Hydroperoxide Activate Human Neutrophils via PKC Activation
Q35734162Vitamin E isoforms directly bind PKCα and differentially regulate activation of PKCα.
Q50751700Vitamin E succinate inhibits proliferation and migration of retinal pigment epithelial cells in vitro: therapeutic implication for proliferative vitreoretinopathy.

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