| scholarly article | Q13442814 |
| P2093 | author name string | Ward CA | |
| Giles WR | |||
| P2860 | cites work | Protein kinase C and lipid signaling for sustained cellular responses | Q28300819 |
| Susceptibility of cloned K+ channels to reactive oxygen species | Q28378738 | ||
| Ca2+- and phospholipid-independent activation of protein kinase C by selective oxidative modification of the regulatory domain | Q34301849 | ||
| Effects of exogenous free radicals on electromechanical function and metabolism in isolated rabbit and guinea pig ventricle. Implications for ischemia and reperfusion injury | Q34574070 | ||
| Direct measurement of free radical generation following reperfusion of ischemic myocardium | Q34602572 | ||
| Modulation of cardiac Na+ channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C | Q35167168 | ||
| Modification of inactivation in cardiac sodium channels: ionic current studies with Anthopleurin-A toxin | Q36435540 | ||
| Phosphorylation of S1505 in the cardiac Na+ channel inactivation gate is required for modulation by protein kinase C. | Q36435813 | ||
| Oxygen-free radicals at myocardial level: effects of ischaemia and reperfusion | Q40539347 | ||
| Strontium, nifedipine and 4-aminopyridine modify the time course of the action potential in cells from rat ventricular muscle | Q41748354 | ||
| Augmentation and subsequent attenuation of Ca2+ current due to lipid peroxidation of the membrane caused by t-butyl hydroperoxide in the rabbit sinoatrial node | Q41833376 | ||
| Alterations in electrical and contractile behavior of isolated cardiomyocytes by hydrogen peroxide: possible ionic mechanisms | Q43550490 | ||
| Oxidative stress alters specific membrane currents in isolated cardiac myocytes | Q43604718 | ||
| Oxidation-induced persistent activation of protein kinase C in hippocampal homogenates | Q43721611 | ||
| Modulation of K+ channels by hydrogen peroxide | Q44114353 | ||
| Potential cellular mechanisms of hydrogen peroxide-induced cardiac arrhythmias | Q45244226 | ||
| Role of protein kinase C in mediating effects of hydrogen peroxide in guinea-pig ventricular myocytes | Q46232120 | ||
| Cellular electrophysiological basis for oxygen radical-induced arrhythmias. A patch-clamp study in guinea pig ventricular myocytes | Q46922801 | ||
| A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties | Q48479782 | ||
| A novel conformationally restricted protein kinase C inhibitor, Ro 31-8425, inhibits human neutrophil superoxide generation by soluble, particulate and post-receptor stimuli | Q48623563 | ||
| Intracellular calcium homeostasis during hydrogen peroxide injury to cultured P388D1 cells. | Q50906462 | ||
| Opposite effects of angiotensin II and the protein kinase C activator OAG on cardiac Na+ channels | Q67509937 | ||
| Modification of cardiac ionic currents by photosensitizer-generated reactive oxygen | Q67965025 | ||
| Abnormal electrical activity induced by free radical generating systems in isolated cardiocytes | Q68074350 | ||
| Effects of oxidant stress on steady-state background currents in isolated ventricular myocytes | Q68263277 | ||
| A video system for measuring motion in contracting heart cells | Q68326828 | ||
| Translocation and enhancement of phosphotransferase activity of protein kinase C following exposure in mouse epidermal cells to oxidants | Q69234942 | ||
| Modification of cardiac action potential by photosensitizer-generated reactive oxygen | Q69725660 | ||
| Comparison of potassium currents in rabbit atrial and ventricular cells | Q69854114 | ||
| Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide | Q70527483 | ||
| Creatine kinase is the main target of reactive oxygen species in cardiac myofibrils | Q71089410 | ||
| Mechanisms of the killing of cultured hepatocytes by hydrogen peroxide | Q71268888 | ||
| Excitation-contraction coupling in single guinea-pig ventricular myocytes exposed to hydrogen peroxide | Q72153674 | ||
| Interactions of H2O2, EGTA and patch pipette recording methods in feline ventricular myocytes | Q72153912 | ||
| Effects of action potential duration on excitation-contraction coupling in rat ventricular myocytes. Action potential voltage-clamp measurements | Q72187813 | ||
| Reperfusion-induced arrhythmias: mechanisms and prevention | Q72584453 | ||
| Heterogeneity of action potential waveforms and potassium currents in rat ventricle | Q72692180 | ||
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 631-642 | |
| P577 | publication date | 1997-05-01 | |
| P1433 | published in | Journal of Physiology | Q7743612 |
| P1476 | title | Ionic mechanism of the effects of hydrogen peroxide in rat ventricular myocytes. | |
| P478 | volume | 500 ( Pt 3) |
| Q34180327 | A mathematical model of the electrophysiological alterations in rat ventricular myocytes in type-I diabetes |
| Q33964929 | A mutation causing Brugada syndrome identifies a mechanism for altered autonomic and oxidant regulation of cardiac sodium currents |
| Q28510409 | A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages |
| Q43287608 | A slowly inactivating sodium current contributes to spontaneous diastolic depolarization of atrial myocytes |
| Q44463965 | Altered excitability of intestinal neurons in primary culture caused by acute oxidative stress |
| Q41873666 | Angiotensin II induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling. |
| Q35147202 | Anti-anginal and anti-ischemic effects of late sodium current inhibition |
| Q87331010 | Antiarrhythmic ionic mechanism of Guanfu base A--Selective inhibition of late sodium current in isolated ventricular myocytes from guinea pigs |
| Q52681248 | Antioxidant defense and protection against cardiac arrhythmias: lessons from a mammalian hibernator (the woodchuck). |
| Q60922070 | Arrhythmias and Heart Rate: Mechanisms and Significance of a Relationship |
| Q90282403 | Arrhythmogenic mechanisms of obstructive sleep apnea in heart failure patients |
| Q38076111 | Atrial fibrillation in the elderly: the potential contribution of reactive oxygen species |
| Q50088130 | Barbaloin inhibits ventricular arrhythmias in rabbits by modulating voltage-gated ion channels |
| Q51448905 | Both D-cis- and L-cis-diltiazem attenuate hydrogen peroxide-induced derangements in rat hearts. |
| Q54541558 | Calmodulin kinase II and protein kinase C mediate the effect of increased intracellular calcium to augment late sodium current in rabbit ventricular myocytes. |
| Q35019379 | Cardiac fibrosis as a determinant of ventricular tachyarrhythmias |
| Q36201210 | Changes in Intracellular Na+ following Enhancement of Late Na+ Current in Virtual Human Ventricular Myocytes |
| Q28505358 | Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy |
| Q44653155 | Differential modulation of voltage-dependent K+currents in colonic smooth muscle by oxidants |
| Q36193662 | Docosahexaenoic Acid reduces the incidence of early afterdepolarizations caused by oxidative stress in rabbit ventricular myocytes |
| Q46550780 | Effect of hydrogen peroxide on persistent sodium current in guinea pig ventricular myocytes |
| Q51380036 | Effect of hydrogen peroxide on the membrane currents of sinoatrial node cells from rabbit heart. |
| Q43734702 | Effects of hydrogen peroxide on the transient outward current in rabbit atrial myocytes |
| Q39144763 | Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets |
| Q36042700 | Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarization-mediated ventricular arrhythmias |
| Q37231007 | F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models |
| Q35825880 | Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts |
| Q52544321 | Gradient of sodium current across the left ventricular wall of adult rat hearts. |
| Q46346604 | H(2)O(2)-induced left ventricular dysfunction in isolated working rat hearts is independent of calcium accumulation |
| Q40853498 | Hydrogen peroxide attenuates store-operated calcium entry and enhances calcium extrusion in thyroid FRTL-5 cells |
| Q59200909 | Hydrogen peroxide causes cardiac dysfunction independent from its effects on matrix metalloproteinase-2 activationThis paper is one of a selection of papers published in this Special Issue, entitled The Cellular and Molecular Basis of Cardiovascular |
| Q44014674 | Hydrogen peroxide-induced intracellular acidosis and electromechanical inhibition in the diseased human ventricular myocardium |
| Q89787652 | Hypoxia Produces Pro-arrhythmic Late Sodium Current in Cardiac Myocytes by SUMOylation of NaV1.5 Channels |
| Q39974711 | Identification and physiological activity of survival factor released from cardiomyocytes during ischaemia and reperfusion |
| Q37706949 | In silico assessment of drug safety in human heart applied to late sodium current blockers |
| Q61454180 | In vitro effects of hydrogen peroxide on rat uterine contraction before and during pregnancy |
| Q37430956 | Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress |
| Q46446978 | Increased susceptibility of spontaneously hypertensive rats to ventricular tachyarrhythmias in early hypertension. |
| Q51435997 | Inhibition of Na+ channel or Na+/H+ exchanger attenuates the hydrogen peroxide-induced derangements in isolated perfused rat heart. |
| Q40224613 | Inhibition of cardiac voltage-gated sodium channels by grape polyphenols. |
| Q36507053 | Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine |
| Q45136282 | Inhibitions of late INa and CaMKII act synergistically to prevent ATX-II-induced atrial fibrillation in isolated rat right atria |
| Q34032676 | Irregularly Appearing Early Afterdepolarizations in Cardiac Myocytes: Random Fluctuations or Dynamical Chaos? |
| Q42016775 | Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII. |
| Q37156945 | Late sodium current inhibition as a new cardioprotective approach |
| Q51941991 | Mathematical simulations of the effects of altered AMP-kinase activity on I and the action potential in rat ventricle. |
| Q34901966 | Mechanism of action of the new anti-ischemia drug ranolazine |
| Q102152202 | Mechanisms of ranolazine pretreatment in preventing ventricular tachyarrhythmias in diabetic db/db mice with acute regional ischemia-reperfusion injury |
| Q27024176 | Mechanisms of sudden cardiac death: oxidants and metabolism |
| Q35178680 | Mitochondria-derived ROS bursts disturb Ca²⁺ cycling and induce abnormal automaticity in guinea pig cardiomyocytes: a theoretical study |
| Q60046140 | Mitochondrial Dysfunction-Associated Arrhythmogenic Substrates in Diabetes Mellitus |
| Q58130055 | Mitochondrial-Mediated Oxidative Ca/Calmodulin-Dependent Kinase II Activation Induces Early Afterdepolarizations in Guinea Pig Cardiomyocytes: An In Silico Study |
| Q35149277 | NF-kappaB-dependent transcriptional regulation of the cardiac scn5a sodium channel by angiotensin II. |
| Q33624234 | Oxidative Stress-Induced Afterdepolarizations and Protein Kinase C Signaling |
| Q73153916 | Oxidative injury of isolated cardiomyocytes: dependence on free radical species |
| Q43246929 | Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias. |
| Q42561090 | Oxidative-stress-induced afterdepolarizations and calmodulin kinase II signaling |
| Q37297663 | Parathyroid hormone activates TRPV5 via PKA-dependent phosphorylation |
| Q37276416 | Pathophysiology of the cardiac late Na current and its potential as a drug target |
| Q48196534 | Persistent sodium current and Na+/H+ exchange contributes to the augmentation of the reverse Na+/Ca2+ exchange during hypoxia or acute ischemia in ventricular myocytes |
| Q38841829 | Pharmacological Management of Chronic Stable Angina: Focus on Ranolazine |
| Q53629078 | Protein kinase C and Ca(2+) -calmodulin-dependent protein kinase II mediate the enlarged reverse INCX induced by ouabain-increased late sodium current in rabbit ventricular myocytes. |
| Q45069870 | Pyruvate prevents cardiac dysfunction and AMP-activated protein kinase activation by hydrogen peroxide in isolated rat hearts |
| Q37495337 | Ranolazine for congenital and acquired late INa-linked arrhythmias: in silico pharmacological screening. |
| Q28260201 | Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity |
| Q46624550 | Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulation |
| Q35599994 | Ranolazine reduces Ca2+ overload and oxidative stress and improves mitochondrial integrity to protect against ischemia reperfusion injury in isolated hearts |
| Q34573997 | Ranolazine, an inhibitor of the late sodium channel current, reduces postischemic myocardial dysfunction in the rabbit |
| Q38196174 | Reactive oxygen species and excitation-contraction coupling in the context of cardiac pathology |
| Q37362566 | Reactive oxygen species modulate neuronal excitability in rat intrinsic cardiac ganglia |
| Q42218987 | Reactive oxygen species-activated Ca/calmodulin kinase IIδ is required for late I(Na) augmentation leading to cellular Na and Ca overload. |
| Q38035054 | Redox control of cardiac excitability |
| Q46689827 | Redox reaction modulates transient and persistent sodium current during hypoxia in guinea pig ventricular myocytes |
| Q38035382 | Redox regulation of sodium and calcium handling |
| Q88598915 | Regional increase in ROS within stretched region exacerbates arrhythmias in rat trabeculae with nonuniform contraction |
| Q47651784 | Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and C. |
| Q38369684 | Regulation of the cardiac Na+ channel NaV1.5 by post-translational modifications. |
| Q41811863 | Role of redox state in modulation of ion channel function by fatty acids and phospholipids |
| Q27339434 | Role of sodium and calcium dysregulation in tachyarrhythmias in sudden cardiac death |
| Q36104438 | Role of the transient outward potassium current in the genesis of early afterdepolarizations in cardiac cells |
| Q37599625 | Safety and Efficacy of Ranolazine for the Treatment of Chronic Angina Pectoris. |
| Q37658443 | Selective inhibition of late sodium current suppresses ventricular tachycardia and fibrillation in intact rat hearts |
| Q33760881 | Statins Decrease Oxidative Stress and ICD Therapies. |
| Q37200197 | Stretch-activated channel activation promotes early afterdepolarizations in rat ventricular myocytes under oxidative stress |
| Q30622882 | Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine |
| Q30486315 | Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias |
| Q44408343 | Tamoxifen inhibits Na+ and K+ currents in rat ventricular myocytes |
| Q39663271 | Targeting cardiac fibrosis: a new frontier in antiarrhythmic therapy? |
| Q35543129 | Targeting the late component of the cardiac L-type Ca2+ current to suppress early afterdepolarizations |
| Q38060419 | The Ca-calmodulin dependent kinase II: a promising target for future antiarrhythmic therapies? |
| Q38821307 | The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine |
| Q46163207 | The antianginal agent, ranolazine, reduces myocardial infarct size but does not alter anatomic no-reflow or regional myocardial blood flow in ischemia/reperfusion in the rabbit |
| Q37345048 | The arrhythmogenic consequences of increasing late INa in the cardiomyocyte |
| Q37028768 | The cardiac persistent sodium current: an appealing therapeutic target? |
| Q26861522 | The late Na current as a therapeutic target: where are we? |
| Q26864515 | The late Na+ current--origin and pathophysiological relevance |
| Q26823149 | The role of late I Na in development of cardiac arrhythmias |
| Q34658210 | The role of sodium channel current in modulating transmural dispersion of repolarization and arrhythmogenesis. |
| Q42492910 | Tyrosine kinase and phosphatase regulation of slow delayed-rectifier K+ current in guinea-pig ventricular myocytes |
| Q46480933 | Ultraviolet photoalteration of late Na+ current in guinea-pig ventricular myocytes. |
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