Structural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches.

scientific article

Structural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.STR.2004.03.004
P698PubMed publication ID15062086
P5875ResearchGate publication ID8639587

P50authorRolf BoelensQ28468897
Cyril DominguezQ37391239
Alexandre BonvinQ43077287
Sebastiaan WinklerQ73394576
P2093author name stringH Th Marc Timmers
Frederik M A van Schaik
P2860cites workCrystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
P433issue4
P304page(s)633-644
P577publication date2004-04-01
P1433published inStructureQ15709970
P1476titleStructural model of the UbcH5B/CNOT4 complex revealed by combining NMR, mutagenesis, and docking approaches
P478volume12

Reverse relations

cites work (P2860)
Q28596587A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125
Q58692523A Dynamic Overview of Antimicrobial Peptides and Their Complexes
Q27678094A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms
Q24336529A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system
Q24303673A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.
Q58484044A structural model for the adduct between cytochrome c and cytochrome c oxidase
Q27646351Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78
Q24314049An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair
Q35378702Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface.
Q40660615Architecture of the ubiquitylation module of the yeast Ccr4-Not complex.
Q27676126Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b
Q51584347Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms: New structural insights to unravel CCR4-NOT mRNA processing machinery.
Q28553904Blocking the Interactions between Calcium-Bound S100A12 Protein and the V Domain of RAGE Using Tranilast
Q55342042Blocking the interaction between S100A9 protein and RAGE V domain using S100A12 protein.
Q29619578Building ubiquitin chains: E2 enzymes at work
Q44942257Combining NMR and small angle X-ray and neutron scattering in the structural analysis of a ternary protein-RNA complex
Q34017765Comprehensively surveying structure and function of RING domains from Drosophila melanogaster
Q36949327Conformer selection and induced fit in flexible backbone protein-protein docking using computational and NMR ensembles
Q27677106Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions
Q30980755Data-driven docking for the study of biomolecular complexes
Q38027979Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex
Q27644344Determination of the Three-Dimensional Structure of the Mrf2−DNA Complex Using Paramagnetic Spin Labeling †
Q42160240Different HECT domain ubiquitin ligases employ distinct mechanisms of polyubiquitin chain synthesis
Q28484775Dynamic control of selectivity in the ubiquitination pathway revealed by an ASP to GLU substitution in an intra-molecular salt-bridge network
Q37588018Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination
Q35065158E2 conjugating enzyme selectivity and requirements for function of the E3 ubiquitin ligase CHIP.
Q24293777E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages
Q24316067E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification
Q28301074E2s: structurally economical and functionally replete
Q27679081Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3
Q33827610Fertilization in C. elegans requires an intact C-terminal RING finger in sperm protein SPE-42
Q42196349Functional characterization of residues required for the herpes simplex virus 1 E3 ubiquitin ligase ICP0 to interact with the cellular E2 ubiquitin-conjugating enzyme UBE2D1 (UbcH5a)
Q27649110High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment
Q24293751Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription
Q35774953Human proteome-scale structural modeling of E2-E3 interactions exploiting interface motifs
Q41818024Identification of a non-covalent ternary complex formed by PIAS1, SUMO1, and UBC9 proteins involved in transcriptional regulation
Q28118367Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligase
Q30363357Insights into the structure and architecture of the CCR4-NOT complex
Q28603010Integrative NMR for biomolecular research
Q27650632Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes
Q34230579Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases
Q35844930Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae
Q27663996Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4
Q24319435Molecular basis of Pirh2-mediated p53 ubiquitylation
Q39710578PHF8 targets histone methylation and RNA polymerase II to activate transcription.
Q44099201RING domains functioning as E3 ligases reveal distinct structural features: a molecular dynamics simulation study.
Q26853207RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis
Q24315785Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex
Q27678117Selective Recruitment of an E2 Ubiquitin Complex by an E3 Ubiquitin Ligase
Q24294553Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4
Q46404140Solution structure of the C-terminal domain of TFIIH P44 subunit reveals a novel type of C4C4 ring domain involved in protein-protein interactions
Q41768339Solution structure of the ubiquitin-associated domain of human BMSC-UbP and its complex with ubiquitin
Q22254803Structural and functional characterization of the monomeric U-box domain from E4B
Q34575687Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.
Q33987001Structural and functional insights to ubiquitin-like protein conjugation.
Q24621898Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl
Q24293794Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1
Q38916854Structural insights into the catalysis and regulation of E3 ubiquitin ligases
Q35064292Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.
Q42939085Structural model of ubiquitin transfer onto an artificial RING finger as an E3 ligase
Q27652850Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
Q27643921Structure, interactions, and dynamics of the RING domain from human TRAF6
Q81596406Structure-based approaches to create new E2-E3 enzyme pairs
Q27652077Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment
Q24306758The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
Q34460686The MDM2 gene family
Q38200937The dynamic duo: combining NMR and small angle scattering in structural biology
Q24299024Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53
Q31102154Tranilast Blocks the Interaction between the Protein S100A11 and Receptor for Advanced Glycation End Products (RAGE) V Domain and Inhibits Cell Proliferation
Q24323309Ubiquitin-conjugating enzyme UBE2D2 is responsible for FBXW2 (F-box and WD repeat domain containing 2)-mediated human GCM1 (glial cell missing homolog 1) ubiquitination and degradation
Q29619405X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution

Search more.