Intramolecular regulation of the opposing (p)ppGpp catalytic activities of Rel(Seq), the Rel/Spo enzyme from Streptococcus equisimilis

scientific article

Intramolecular regulation of the opposing (p)ppGpp catalytic activities of Rel(Seq), the Rel/Spo enzyme from Streptococcus equisimilis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JB.184.11.2878-2888.2002
P932PMC publication ID135074
P698PubMed publication ID12003927
P5875ResearchGate publication ID247694002

P2093author name stringHelen Murphy
Michael Cashel
Undine Mechold
Larissa Brown
P2860cites workSynthesis of Guanosine Tetra- and Pentaphosphate Requires the Presence of a Codon-Specific, Uncharged Transfer Ribonucleic Acid in the Acceptor Site of RibosomesQ24564295
Overexpression of the relA gene in Escherichia coli.Q54700280
A rapid test for the rel a mutation in E. coliQ57177256
Residual guanosine 3',5'-bispyrophosphate synthetic activity of relA null mutants can be eliminated by spoT null mutationsQ70119536
Escherichia coli ppGpp synthetase II activity requires spoTQ70119540
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Dissection of glutathionylspermidine synthetase/amidase from Escherichia coli into autonomously folding and functional synthetase and amidase domainsQ71985246
Co-ordination of legionella pneumophila virulence with entry into stationary phase by ppGppQ78127783
A switch in the kinase domain of rat testis 6-phosphofructo-2-kinase/fructose-2,6-bisphosphataseQ27619677
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoterQ27860697
Guanosine 5'-triphosphate, 3'-diphosphate 5'-phosphohydrolase. Purification and substrate specificityQ28260926
Isocitrate dehydrogenase kinase/phosphatase. Kinetic characteristics of the wild-type and two mutant proteinsQ28284364
The stringent response of Mycobacterium tuberculosis is required for long-term survivalQ28486427
Differential regulation of opposing RelMtb activities by the aminoacylation state of a tRNA.ribosome.mRNA.RelMtb complexQ28487211
Cloning and characterization of a bifunctional RelA/SpoT homologue from Mycobacterium tuberculosisQ28487236
The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiationQ28504059
Culture medium for enterobacteriaQ29616466
The HD domain defines a new superfamily of metal-dependent phosphohydrolasesQ31944351
Control of asgE expression during growth and development of Myxococcus xanthusQ33792155
The two opposing activities of adenylyl transferase reside in distinct homologous domains, with intramolecular signal transductionQ33887447
Regulation of Escherichia coli RelA requires oligomerization of the C-terminal domainQ33995334
Stringent response activates quorum sensing and modulates cell density-dependent gene expression in Pseudomonas aeruginosaQ33996839
Functional analysis of relA and rshA, two relA/spoT homologues of Streptomyces coelicolor A3(2).Q34011883
Revisiting the stringent response, ppGpp and starvation signaling.Q34204989
In vitro degradation of guanosine 5'-diphosphate, 3'-diphosphateQ35051944
Arabidopsis RelA/SpoT homologs implicate (p)ppGpp in plant signalingQ35122280
The guanosine nucleotide (p)ppGpp initiates development and A-factor production in myxococcus xanthusQ35195957
Functional analysis of a relA/spoT gene homolog from Streptococcus equisimilisQ35603438
Cloning the spoT gene of Escherichia coli: identification of the spoT gene productQ36338420
Mutations in the spoT gene of Salmonella typhimurium: effects on his operon expressionQ36363316
Cloning and characterization of a relA/spoT homologue from Bacillus subtilisQ36893182
Comparative genomics and evolution of genes encoding bacterial (p)ppGpp synthetases/hydrolases (the Rel, RelA and SpoT proteins).Q37873492
The relA/spoT-homologous gene in Streptomyces coelicolor encodes both ribosome-dependent (p)ppGpp-synthesizing and -degrading activities.Q39567167
The rel gene is essential for in vitro growth of Staphylococcus aureusQ39587810
Characterization of the stringent and relaxed responses of Streptococcus equisimilisQ39845359
In vitro degradation of guanosine tetraphosphate (ppGpp) by an enzyme associated with the ribosomal fraction fromEscherichia coliQ40847037
Mutants of Escherichia coli defective in the degradation of guanosine 5′-triphosphate, 3′-diphosphate (pppGpp)Q41023922
Basal ppGpp level adjustment shown by new spoT mutants affect steady state growth rates and rrnA ribosomal promoter regulation in Escherichia coliQ42489489
Control of spoT-dependent ppGpp synthesis and degradation in Escherichia coliQ42518408
A relA/spoT homologous gene from Streptomyces coelicolor A3(2) controls antibiotic biosynthetic genesQ42630092
Codon-usage based regulation of colicin K synthesis by the stress alarmone ppGpp.Q43674779
Guanosine Tetra- and Pentaphosphate Promote Accumulation of Inorganic Polyphosphate in Escherichia coliQ46183930
Guanosine tetraphosphate inhibits protein synthesis in vivo. A possible protective mechanism for starvation stress in Escherichia coliQ46263543
Ectopic production of guanosine penta- and tetraphosphate can initiate early developmental gene expression in Myxococcus xanthusQ46611032
Characterization of the relA/spoT gene from Bacillus stearothermophilus.Q47821931
Characterization of the relA1 mutation and a comparison of relA1 with new relA null alleles in Escherichia coliQ48280672
Mutational analysis of the Escherichia coli spoT gene identifies distinct but overlapping regions involved in ppGpp synthesis and degradation.Q54592691
Isolation and properties of a ribosome-bound factor required for ppGpp and ppGpp synthesis in Escherichia coli.Q54610023
P4510describes a project that usesImageQuantQ112270642
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectStreptococcus equisimilisQ7623348
P304page(s)2878-2888
P577publication date2002-06-01
P1433published inJournal of BacteriologyQ478419
P1476titleIntramolecular regulation of the opposing (p)ppGpp catalytic activities of Rel(Seq), the Rel/Spo enzyme from Streptococcus equisimilis
P478volume184

Reverse relations

cites work (P2860)
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