Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation

scientific article

Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M402362200
P698PubMed publication ID15073167

P50authorAnn-Lii ChengQ38639483
Kun-Huei YehQ57092723
P2093author name stringShuang-En Chuang
Pei Yen Yeh
Ying Chyi Song
P433issue25
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
P304page(s)26143-26148
P577publication date2004-04-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleSuppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation
P478volume279

Reverse relations

cites work (P2860)
Q24626425A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication
Q24313389A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity
Q39332430Anti-Metastatic Effect of Semi-Purified Nuphar Lutea Leaf Extracts
Q28391506Basic principles and emerging concepts in the redox control of transcription factors
Q38779104CXCR3 signaling in glial cells ameliorates experimental autoimmune encephalomyelitis by restraining the generation of a pro-Th17 cytokine milieu and reducing CNS-infiltrating Th17 cells
Q34089685Cellular Responses to Cisplatin‐Induced DNA Damage
Q54964255Characterization of Site-Specific Phosphorylation of NF-κB p65 in Retinal Cells in Response to High Glucose and Cytokine Polarization.
Q28481351Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells
Q37491590Cleavage and proteasome-mediated degradation of the basal transcription factor TFIIA.
Q41780620Conditional knockout mice reveal an essential role of protein phosphatase 4 in thymocyte development and pre-T-cell receptor signaling
Q33636430Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases
Q37269248DEPTOR promotes survival of cervical squamous cell carcinoma cells and its silencing induces apoptosis through downregulating PI3K/AKT and by up-regulating p38 MAP kinase
Q37277091Epigenetic roles of MLL oncoproteins are dependent on NF-κB
Q90464925Functional Roles of Protein Phosphatase 4 in Multiple Aspects of Cellular Physiology: A Friend and A Foe
Q54977122Gastrin inhibits gastric cancer progression through activating the ERK-P65-miR23a/27a/24 axis.
Q35787254Genome-wide siRNA screen for mediators of NF-κB activation
Q28291669Good cop, bad cop: the different faces of NF-kappaB
Q35559402High expression of protein phosphatase 4 is associated with the aggressive malignant behavior of colorectal carcinoma
Q24299472Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4.
Q59125995Mechanisms of NF-κB p65 and strategies for therapeutic manipulation
Q40238594Modulation of the age-related nuclear factor-kappaB (NF-kappaB) pathway by hesperetin
Q92069747NF-kB as a key player in regulation of cellular radiation responses and identification of radiation countermeasures
Q36906395Neuronatin: a new inflammation gene expressed on the aortic endothelium of diabetic mice.
Q43110174Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs
Q53265126Oral administration of oleuropein attenuates cisplatin-induced acute renal injury in mice through inhibition of ERK signaling.
Q36160050Overexpression of protein phosphatase 4 correlates with poor prognosis in patients with stage II pancreatic ductal adenocarcinoma
Q91598891PP4 deficiency leads to DNA replication stress that impairs immunoglobulin class switch efficiency
Q28542954PP4 is essential for germinal center formation and class switch recombination in mice
Q42224760PP4R1 accelerates cell growth and proliferation in HepG2 hepatocellular carcinoma
Q34072134Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
Q36637883Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
Q37723806Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway
Q38737137Protein phosphatase 4 catalytic subunit is overexpressed in glioma and promotes glioma cell proliferation and invasion
Q34343619Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation
Q34347995Protein phosphatase 4 is a positive regulator of hematopoietic progenitor kinase 1.
Q37111119Protein phosphatase 4 mediates localization of the Miranda complex during Drosophila neuroblast asymmetric divisions.
Q39836083Protein phosphatase 4 regulates apoptosis in leukemic and primary human T-cells.
Q36137554Protein phosphatase 4--from obscurity to vital functions
Q91826128Protein phosphatase 6 is a key factor regulating spermatogenesis
Q36156141ROCK I-mediated activation of NF-kappaB by RhoB
Q35066471Role of mitogen-activated protein kinases in peptidoglycan-induced expression of inducible nitric oxide synthase and nitric oxide in mouse peritoneal macrophages: extracellular signal-related kinase, a negative regulator
Q92932427Role of protein phosphatases PP1, PP2A, PP4 and Cdc14 in the DNA damage response
Q92945873Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy
Q26752951The Regulation of NF-κB Subunits by Phosphorylation
Q55035093The Renin-Angiotensin-Aldosterone System as a Therapeutic Target in Late Injury Caused by Ischemia-Reperfusion.
Q38126565The complexity of NF-κB signaling in inflammation and cancer
Q39301372Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation

Search more.