scholarly article | Q13442814 |
P50 | author | Michael J Holtzman | Q88059520 |
Steven L Brody | Q88932351 | ||
Edy Yong Kim | Q90559889 | ||
Alexander Patterson | Q92621911 | ||
Yingjian You | Q114293992 | ||
William T Roswit | Q114293997 | ||
Jeffrey W. Tyner | Q42182973 | ||
Anand C. Patel | Q55711828 | ||
John Battaile Hall | Q64867142 | ||
P2093 | author name string | Mario Castro | |
Jeffrey D Morton | |||
Kyotaro Ide | |||
Melanie S Spoor | |||
Mark R Pelletier | |||
P2860 | cites work | Segregation of receptor and ligand regulates activation of epithelial growth factor receptor | Q24298164 |
Activation of the epidermal growth factor receptor by respiratory syncytial virus results in increased inflammation and delayed apoptosis | Q24314721 | ||
Platelet-activating factor receptor and ADAM10 mediate responses to Staphylococcus aureus in epithelial cells | Q28215261 | ||
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways | Q28274882 | ||
Interleukin-13: central mediator of allergic asthma | Q28291712 | ||
Mouse strain modulates the role of the ciliated cell in acute tracheobronchial airway injury-distal airways | Q28344816 | ||
Oxidative stress causes mucin synthesis via transactivation of epidermal growth factor receptor: role of neutrophils | Q28368945 | ||
Activation of the EGF receptor signaling pathway in human airway epithelial cells exposed to metals | Q28376514 | ||
CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection | Q28508659 | ||
IL-13-induced Clara cell secretory protein expression in airway epithelium: role of EGFR signaling pathway | Q28568180 | ||
Distribution of epidermal growth factor receptor and ligands during bronchiolar epithelial repair from naphthalene-induced Clara cell injury in the mouse | Q28762835 | ||
ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions | Q29615216 | ||
Vanadium stimulates human bronchial epithelial cells to produce heparin-binding epidermal growth factor-like growth factor: a mitogen for lung fibroblasts | Q31834419 | ||
Epidermal growth factor receptors: critical mediators of multiple receptor pathways | Q33597368 | ||
The distribution and structure of cells in the tracheal epithelium of the mouse | Q72855518 | ||
Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival | Q73755005 | ||
Epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor localization in the baboon (Papio anubis) oviduct during steroid treatment and the menstrual cycle | Q74008173 | ||
Combinatorial chemoprevention of intestinal neoplasia | Q74268548 | ||
Differential signaling and regulation of apical vs. basolateral EGFR in polarized epithelial cells | Q77649292 | ||
Immunolocalization of transforming growth factor alpha and epidermal growth factor receptor in lungs of patients with cystic fibrosis | Q78109803 | ||
The role of the epidermal growth factor receptor in sustaining neutrophil inflammation in severe asthma | Q78966845 | ||
Integration of growth factor, extracellular matrix, and retinoid signals during bronchial epithelial cell differentiation | Q33781551 | ||
Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma | Q33852115 | ||
Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness | Q33883942 | ||
Effects of paramyxoviral infection on airway epithelial cell Foxj1 expression, ciliogenesis, and mucociliary function | Q34104058 | ||
Role of f-box factor foxj1 in differentiation of ciliated airway epithelial cells | Q34207601 | ||
Expression of epidermal growth factor (EGF) receptor and its ligands, EGF and transforming growth factor-alpha, in human fallopian tubes | Q34481293 | ||
Epidermal growth factor system regulates mucin production in airways | Q35065617 | ||
Tumor necrosis factor alpha-converting enzyme mediates MUC5AC mucin expression in cultured human airway epithelial cells | Q36161369 | ||
Interleukin 12 p40 production by barrier epithelial cells during airway inflammation | Q36376199 | ||
Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli | Q37273953 | ||
Expression of c-erbB receptors and ligands in human bronchial mucosa | Q38325152 | ||
Viral induction of a chronic asthma phenotype and genetic segregation from the acute response | Q39738116 | ||
IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells | Q39947194 | ||
EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes | Q40530279 | ||
Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor | Q40732059 | ||
Increased expression of the human Ca2+-activated Cl- channel 1 (CaCC1) gene in the asthmatic airway | Q40737976 | ||
Human eosinophils induce mucin production in airway epithelial cells via epidermal growth factor receptor activation | Q40769833 | ||
Nuclear localization of EGF receptor and its potential new role as a transcription factor | Q40782527 | ||
Involvement of the epidermal growth factor receptor in epithelial repair in asthma | Q40870399 | ||
Requirement for IL-13 independently of IL-4 in experimental asthma | Q41881960 | ||
The epidermal growth factor receptor (EGF-R) is present on the basolateral, but not the apical, surface of enterocytes in the human gastrointestinal tract | Q41885559 | ||
Pathogenesis of mucous cell metaplasia in a murine asthma model | Q41925077 | ||
IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation | Q42442635 | ||
Ultrastructure of goblet-cell metaplasia from Clara cell in the allergic asthmatic airway inflammation in a mouse model of asthma in vivo | Q42453587 | ||
Distribution of epidermal growth factor and epidermal growth factor receptor in human lung: immunohistochemical and immunoelectron-microscopic studies | Q42496037 | ||
Relationship of epidermal growth factor receptors to goblet cell production in human bronchi | Q42499386 | ||
Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells | Q42515752 | ||
Expression of epidermal growth factor and its receptor in normal and diseased human kidney: an immunohistochemical and in situ hybridization study | Q42518413 | ||
Expression and localization of epidermal growth factor, transforming growth factor-alpha, and localization of their common receptor in fetal human lung development | Q42527275 | ||
Activation of the EGF receptor signaling pathway in airway epithelial cells exposed to Utah Valley PM. | Q43660377 | ||
Interleukin-13 induces goblet cell differentiation in primary cell culture from Guinea pig tracheal epithelium | Q44191935 | ||
Mucin is produced by clara cells in the proximal airways of antigen-challenged mice | Q44932430 | ||
IL-13 induces mucin production by stimulating epidermal growth factor receptors and by activating neutrophils. | Q46023002 | ||
Modification of the Stat1 SH2 domain broadly improves interferon efficacy in proportion to p300/CREB-binding protein coactivator recruitment | Q46656248 | ||
IL-4 receptor signaling in Clara cells is required for allergen-induced mucus production | Q47732346 | ||
Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis. | Q47897731 | ||
Expression of epidermal growth factor and epidermal growth factor receptor immunoreactivity in the asthmatic human airway | Q47991162 | ||
Interleukin-13 and -4 expression in the central airways of smokers with chronic bronchitis. | Q51646661 | ||
Ontogeny of epidermal growth factor receptor and lipocortin-1 in fetal and neonatal human lungs. | Q52242492 | ||
Number and proliferation of clara cells in normal human airway epithelium | Q57890950 | ||
Eosinophils Express Functional IL-13 in Eosinophilic Inflammatory Diseases | Q61959803 | ||
Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells | Q70818579 | ||
Immunolocalization of transforming growth factor-alpha, epidermal growth factor (EGF), and EGF-receptor in normal and injured developing human lung | Q71051727 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 309-321 | |
P577 | publication date | 2006-02-01 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals | |
P478 | volume | 116 |
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Q35614978 | CD45/CD11b positive subsets of adult lung anchorage-independent cells harness epithelial stem cells in culture |
Q51625277 | CYT003, a TLR9 agonist, in persistent allergic asthma - a randomized placebo-controlled Phase 2b study. |
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Q54352157 | Epidermal growth factor receptor signaling mediates vesicant-induced airway epithelial secretion of interleukin-6 and production of mucin. |
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