Michael J Holtzman

researcher

Michael J Holtzman is …
instance of (P31):
humanQ5

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P496ORCID iD0000-0001-8750-3716

P166award receivedFellow of the American Association for the Advancement of ScienceQ5442484
P108employerWashington University in St. LouisQ777403
P734family nameHoltzmanQ21508288
HoltzmanQ21508288
HoltzmanQ21508288
P735given nameMichaelQ4927524
MichaelQ4927524
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q35971078"Hit-and-run" effects of paramyxoviruses as a basis for chronic respiratory disease
Q30521450A New Electrospray Aerosol Generator with High Particle Transmission Efficiency
Q36131651A centennial history of research on asthma pathogenesis
Q42738479A transgenic FOXJ1-Cre system for gene inactivation in ciliated epithelial cells.
Q36237040Acute and chronic airway responses to viral infection: implications for asthma and chronic obstructive pulmonary disease
Q80752775Airway epithelial versus immune cell Stat1 function for innate defense against respiratory viral infection
Q48599917Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum.
Q26823579Alternatively activated macrophages and airway disease
Q84500726Alternatively activated macrophages as cause or effect in airway disease
Q51489659An acoustofluidic sputum liquefier.
Q43688175Antigen-nonspecific recruitment of Th2 cells to the lung as a mechanism for viral infection-induced allergic asthma
Q35923242Antiviral IFN-γ responses of monocytes at birth predict respiratory tract illness in the first year of life
Q35160445Apoptosis in the airways: another balancing act in the epithelial program.
Q36129053Asthma as a chronic disease of the innate and adaptive immune systems responding to viruses and allergens
Q44730526Asthma exacerbations after glucocorticoid withdrawal reflects T cell recruitment to the airway
Q112641961Asthma reduces glioma formation by T cell decorin-mediated inhibition of microglia
Q91361919Author Correction: The choroid plexus is an important circadian clock component
Q34331327Blocking airway mucous cell metaplasia by inhibiting EGFR antiapoptosis and IL-13 transdifferentiation signals.
Q24629014Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active
Q43180215Chemokine complexity: the case for CCL5.
Q45103698Chemokine signaling regulates apoptosis as well as immune cell traffic in host defense
Q33799656Chemosensory functions for pulmonary neuroendocrine cells
Q34268993Cigarette smoke induces nucleic-acid oxidation in lung fibroblasts
Q112650259Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate
Q53539376Controls for lung dendritic cell maturation and migration during respiratory viral infection.
Q45766026Correction: SH2 Modified STAT1 Induces HLA-I Expression and Improves IFN-γ Signaling in IFN-α Resistant HCV Replicon Cells.
Q34222345Cutting Edge: CD49d+ Neutrophils Induce FcεRI Expression on Lung Dendritic Cells in a Mouse Model of Postviral Asthma
Q50736187Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation.
Q36232689Defining and adjusting divergent host responses to viral infection
Q114599006Dentate gyrus morphogenesis is regulated by β-CATENIN function in hem-derived fimbrial glia
Q34477691Detection of respiratory viruses and the associated chemokine responses in serious acute respiratory illness
Q44444560Detection of severe human metapneumovirus infection by real-time polymerase chain reaction and histopathological assessment
Q51723360Determinants of outcome for patients admitted to a long-term ventilator unit.
Q35082461Developing the epithelial, viral, and allergic paradigm for asthma: Giles F. Filley lecture.
Q44772898Differential role of Janus family kinases (JAKs) in interferon-gamma-induced lung epithelial ICAM-1 expression: involving protein interactions between JAKs, phospholipase Cgamma, c-Src, and STAT1.
Q37001817Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection
Q60727869Does chloride channel accessory 3 have a role in arthritis pain? A study on murine antigen-induced arthritis
Q35183997Drug development for asthma
Q36949866Emerging role of dendritic cells in respiratory viral infection
Q42118445Epithelial Chloride Transport by CFTR Requires TMEM16A.
Q34720201Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma.
Q30441389Epithelial cell proliferation contributes to airway remodeling in severe asthma
Q65000582Genetic segregation of airway disease traits despite redundancy of calcium-activated chloride channel family members.
Q43412278Genetic variability of human metapneumovirus infection: evidence of a shift in viral genotype without a change in illness
Q97530052Group 2 Innate Lymphoid Cells Must Partner with the Myeloid-Macrophage Lineage for Long-Term Postviral Lung Disease
Q24301056Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain
Q28483402High throughput screening for small molecule enhancers of the interferon signaling pathway to drive next-generation antiviral drug discovery
Q34824028High-throughput screening normalized to biological response: application to antiviral drug discovery
Q36466493Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis
Q35186305Host epithelial-viral interactions as cause and cure for asthma
Q84305104Hypersusceptibility to respiratory viruses as a shared mechanism for asthma, chronic obstructive pulmonary disease, and cystic fibrosis
Q27675276IL-13-induced airway mucus production is attenuated by MAPK13 inhibition
Q36810817IL13 activates autophagy to regulate secretion in airway epithelial cells
Q34440425Immune pathways for translating viral infection into chronic airway disease.
Q34482538Immunity, inflammation, and remodeling in the airway epithelial barrier: epithelial-viral-allergic paradigm
Q36423688Immunogenetic programs for viral induction of mucous cell metaplasia
Q34779037Impaired CD8(+) T cell immunity after allogeneic bone marrow transplantation leads to persistent and severe respiratory viral infection
Q33553600Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary disease
Q36414300Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection
Q36229077Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia
Q35023814Influenza virus receptor specificity and cell tropism in mouse and human airway epithelial cells
Q34663804Interferon response and respiratory virus control are preserved in bronchial epithelial cells in asthma
Q43829868Interferon-gamma-induced epithelial ICAM-1 expression and monocyte adhesion. Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway
Q28209456Intravital microscopy comparing T lymphocyte trafficking to the spleen and the mesenteric lymph node
Q46703569Involvement of the p38 MAPK pathway in IL-13-induced mucous cell metaplasia in mouse tracheal epithelial cells
Q26827549Linking acute infection to chronic lung disease. The role of IL-33-expressing epithelial progenitor cells
Q37123845Long-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease.
Q55647022Long-term IL-33–producing epithelial progenitor cells in chronic obstructive lung disease.
Q42559997Macrophage chitinase 1 stratifies chronic obstructive lung disease
Q27490827Melanoma Differentiation-Associated Gene 5 (MDA5) Is Involved in the Innate Immune Response to Paramyxoviridae Infection In Vivo
Q46656248Modification of the Stat1 SH2 domain broadly improves interferon efficacy in proportion to p300/CREB-binding protein coactivator recruitment
Q35812785Molecular heterogeneity in the choroid plexus epithelium: the 22-member γ-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation
Q35994701Monitoring in vivo changes in lung microstructure with ³He MRI in Sendai virus-infected mice
Q31814881Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms
Q34692122New immune pathways from chronic post-viral lung disease
Q34992604Novel mode of ISG15-mediated protection against influenza A virus and Sendai virus in mice
Q34668099OSCAR is a receptor for surfactant protein D that activates TNF-α release from human CCR2+ inflammatory monocytes
Q37395759Oxidative damage to nucleic acids in severe emphysema
Q24631289P-glycoprotein is a major determinant of norbuprenorphine brain exposure and antinociception
Q36299937PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection
Q51221187PET-based Imaging of Chemokine Receptor 2 in Experimental and Disease-related Lung Inflammation.
Q37377444Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma
Q28591976Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells
Q36955908Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease
Q37693601Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases
Q98906984Publisher Correction: SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
Q33756809Reactive oxygen species induce antiviral innate immune response through IFN-λ regulation in human nasal epithelial cells
Q54266462Recurrent wheezing in children following human metapneumovirus infection.
Q39280203Removal of aquaporin-4 from glial and ependymal membranes causes brain water accumulation
Q33883942Respiratory syncytial virus nonstructural proteins NS1 and NS2 mediate inhibition of Stat2 expression and alpha/beta interferon responsiveness
Q35900909Role of PKCdelta in IFN-gamma-inducible CIITA gene expression
Q98665285SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
Q52579592STAT1 activation causes translocation of Bax to the endoplasmic reticulum during the resolution of airway mucous cell hyperplasia by IFN-gamma.
Q36035457STAT1 modification improves therapeutic effects of interferons on lung cancer cells
Q36451996Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.
Q21145827Skin-derived TSLP triggers progression from epidermal-barrier defects to asthma
Q35316115Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.
Q38334057Specification of a Foxj1-dependent lineage in the forebrain is required for embryonic-to-postnatal transition of neurogenesis in the olfactory bulb
Q40139880Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses.
Q35568471TREM-2 promotes macrophage survival and lung disease after respiratory viral infection
Q33756674The Induction of Pattern-Recognition Receptor Expression against Influenza A Virus through Duox2-Derived Reactive Oxygen Species in Nasal Mucosa
Q44873576The Red journal at 25 years. Looking back and looking ahead
Q52655398The choroid plexus is an important circadian clock component.
Q39338365The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation.
Q40107499The microbial metabolite desaminotyrosine protects from influenza through type I interferon.
Q28657590The role of CLCA proteins in inflammatory airway disease
Q36663025The role of airway epithelial cells and innate immune cells in chronic respiratory disease
Q40613525Toxoplasma Effector Recruits the Mi-2/NuRD Complex to Repress STAT1 Transcription and Block IFN-γ-Dependent Gene Expression
Q50686930Tracking cell lineage to rediscover (again) the switch from ciliated to mucous cells.
Q73562472Transition, sunlight, and the art of journal maintenance
Q41919811Triggering Receptor Expressed on Myeloid Cells-2 (TREM-2) expression tracks with M2-like macrophage activity and disease severity in COPD.
Q82034252Viral and Host Strategies to Take Advantage of the Innate Immune Response
Q39738116Viral induction of a chronic asthma phenotype and genetic segregation from the acute response
Q73008335Where are the gaps in asthma research? A counter-perspective

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