The Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance

scientific article

The Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.74.2.1043-1049.2006
P932PMC publication ID1360352
P698PubMed publication ID16428751
P5875ResearchGate publication ID7343709

P2093author name stringEric T Harvill
Mylisa R Pilione
P2860cites workInterleukin-10Q28263225
Multiple defects of immune cell function in mice with disrupted interferon-gamma genesQ28267397
IL-10 inhibits cytokine production by activated macrophagesQ29619453
Adenylate cyclase toxin from Bordetella pertussis synergizes with lipopolysaccharide to promote innate interleukin-10 production and enhances the induction of Th2 and regulatory T cells.Q30449654
Pregenomic comparative analysis between bordetella bronchiseptica RB50 and Bordetella pertussis tohama I in murine models of respiratory tract infectionQ34002563
Multiple roles for Bordetella lipopolysaccharide molecules during respiratory tract infectionQ34005187
Mechanisms of Bordetella pathogenesisQ34100028
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunityQ34529549
Role of Bordetella O antigen in respiratory tract infectionQ34531338
BvgAS-mediated signal transduction: analysis of phase-locked regulatory mutants of Bordetella bronchiseptica in a rabbit modelQ34533729
IL-10-producing T cells suppress immune responses in anergic tuberculosis patientsQ35159232
Interferon-gamma activation of polymorphonuclear neutrophil functionQ35750735
Pathogen-specific T regulatory 1 cells induced in the respiratory tract by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussiQ36369855
Role of antibodies in immunity to Bordetella infectionsQ39741874
Toll-like receptor 4-mediated innate IL-10 activates antigen-specific regulatory T cells and confers resistance to Bordetella pertussis by inhibiting inflammatory pathology.Q40636724
pagP is required for resistance to antibody-mediated complement lysis during Bordetella bronchiseptica respiratory infectionQ40763994
Modulation of host immune responses, induction of apoptosis and inhibition of NF-kappaB activation by the Bordetella type III secretion systemQ40894557
The BvgAS virulence control system regulates type III secretion in Bordetella bronchisepticaQ41025688
The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-betaQ41600919
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cellsQ41684085
Hepatitis C virus non-structural protein 4 suppresses Th1 responses by stimulating IL-10 production from monocytes.Q42981482
Bordetella bronchiseptica PagP is a Bvg‐regulated lipid A palmitoyl transferase that is required for persistent colonization of the mouse respiratory tractQ43544576
IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophagesQ44173170
Bordetella type III secretion and adenylate cyclase toxin synergize to drive dendritic cells into a semimature stateQ44987484
Antibody-mediated bacterial clearance from the lower respiratory tract of mice requires complement component C3.Q47199485
The complex mechanism of antibody-mediated clearance of Bordetella from the lungs requires TLR4.Q47687255
Bordetella type III secretion modulates dendritic cell migration resulting in immunosuppression and bacterial persistenceQ47724256
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alphaQ57339973
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruziQ58843169
Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient miceQ73082077
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
Bordetella bronchisepticaQ137446
P304page(s)1043-1049
P577publication date2006-02-01
P1433published inInfection and ImmunityQ6029193
P1476titleThe Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearance
P478volume74

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cites work (P2860)
Q34446897A Type VI secretion system encoding locus is required for Bordetella bronchiseptica immunomodulation and persistence in vivo
Q37075478Active and passive immunizations with Bordetella colonization factor A protect mice against respiratory challenge with Bordetella bronchiseptica
Q90626707Analysis of the lung microbiota in dogs with Bordetella bronchiseptica infection and correlation with culture and quantitative polymerase chain reaction
Q58758919Blood or Serum Exposure Induce Global Transcriptional Changes, Altered Antigenic Profile, and Increased Cytotoxicity by Classical Bordetellae
Q33384933Boolean network simulations for life scientists
Q33590435Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN
Q91780268Canine Infectious Respiratory Disease
Q58583885Colonization Limits Efficacy, but Not Immunogenicity, of Live-Attenuated Influenza Virus Vaccine and Enhances Pathogenesis After Influenza Challenge
Q40033232Constraint-based network model of pathogen-immune system interactions
Q36746359Decreased leukocyte accumulation and delayed Bordetella pertussis clearance in IL-6-/- mice
Q39335351Development and characterization of attenuated metabolic mutants of Bordetella bronchiseptica for applications in vaccinology.
Q92335399Enhancement of immune response against Bordetella spp. by disrupting immunomodulation
Q41453869Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infection
Q36591125Generating super-shedders: co-infection increases bacterial load and egg production of a gastrointestinal helminth
Q37529638IL-10 induction by Bordetella parapertussis limits a protective IFN-gamma response
Q44797322Identification of a new protective antigen of Bordetella pertussis
Q33672341Immune regulation of a chronic bacteria infection and consequences for pathogen transmission
Q33402920Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity
Q34484529Interleukin-1 Receptor Signaling Is Required To Overcome the Effects of Pertussis Toxin and for Efficient Infection- or Vaccination-Induced Immunity against Bordetella pertussis
Q43078103Lack of cross-protection against Bordetella holmesii after pertussis vaccination
Q33287189Modeling systems-level regulation of host immune responses
Q34130164Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth.
Q33502706O antigen allows B. parapertussis to evade B. pertussis vaccine-induced immunity by blocking binding and functions of cross-reactive antibodies
Q35805470Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine
Q35042275Resident microbiota affect Bordetella pertussis infectious dose and host specificity
Q58773207Respiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice
Q37333410Role of the type III secretion system in a hypervirulent lineage of Bordetella bronchiseptica.
Q51153411Seasonal breeding drives the incidence of a chronic bacterial infection in a free-living herbivore population.
Q37066697Single-dose, virus-vectored vaccine protection against Yersinia pestis challenge: CD4+ cells are required at the time of challenge for optimal protection
Q42080014Snapshot of spatio-temporal cytokine responses to single and co-infections with helminths and bacteria.
Q40022559Supplementation of whole-cell pertussis vaccines with lipopolysaccharide analogs: modification of vaccine-induced immune responses
Q37643836The Bordetella bronchiseptica type III secretion system is required for persistence and disease severity but not transmission in swine
Q37457083The Bordetella type III secretion system effector BteA contains a conserved N-terminal motif that guides bacterial virulence factors to lipid rafts
Q42613134The O antigen is a critical antigen for the development of a protective immune response to Bordetella parapertussis
Q37534202Toll-like receptor 4 limits transmission of Bordetella bronchiseptica.
Q36191639Transcriptional profiling of Bordetella pertussis reveals requirement of RNA chaperone Hfq for Type III secretion system functionality.
Q35913617Use of a genetically defined double mutant strain of Bordetella bronchiseptica lacking adenylate cyclase and type III secretion as a live vaccine
Q36662611Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits.
Q37627029Vesicular Stomatitis Virus-Vectored Multi-Antigen Tuberculosis Vaccine Limits Bacterial Proliferation in Mice following a Single Intranasal Dose
Q37382931Virulence factor secretion and translocation by Bordetella species

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