Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infection

scientific article published on June 2006

Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infection is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/IAI.00185-06
P932PMC publication ID1479272
P698PubMed publication ID16714568
P5875ResearchGate publication ID7066329

P2093author name stringFrank M Szaba
Lawrence W Kummer
Stephen T Smiley
Isis K Mullarky
Michelle A Parent
Lindsey B Wilhelm
P2860cites workYersinia pestis grows within phagolysosomes in mouse peritoneal macrophagesQ37078811
Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogensQ37868873
Cell-mediated protection against pulmonary Yersinia pestis infectionQ39393406
Expression of plasminogen activator pla of Yersinia pestis enhances bacterial attachment to the mammalian extracellular matrix.Q39573935
Plague Immunization. I. Past and Present TrendsQ39940120
Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient miceQ41185362
Stat 4 but not Stat 6 mediated immune mechanisms are essential in protection against plagueQ41461188
The SCID/Beige mouse as a model to investigate protection against Yersinia pestisQ41483548
Protection against experimental bubonic and pneumonic plague by a recombinant capsular F1-V antigen fusion protein vaccineQ41485426
Short- and long-term efficacy of single-dose subunit vaccines against Yersinia pestis in miceQ41485594
Multidrug resistance in Yersinia pestis mediated by a transferable plasmidQ41487671
In vivo neutralization of tumor necrosis factor-alpha and interferon-gamma abrogates resistance to Yersinia enterocolitica infection in miceQ41507498
Plague Bacillus: Survival within Host PhagocytesQ41524761
The role of multiplication of Pasteurella pestis in mononuclear phagocytes in the pathogenesis of flea-borne plague.Q41569171
Immunity in plague; a critical consideration of some recent studies.Q41575211
Interferon-γ: an overview of signals, mechanisms and functionsQ28207081
Nitric oxide and macrophage functionQ29615327
Yersinia pestis--etiologic agent of plagueQ29619320
Pathogenesis of Yersinia pestis infection in BALB/c mice: effects on host macrophages and neutrophilsQ33225645
T cell responses to bacterial infectionQ33711392
Plague as a biological weapon: medical and public health management. Working Group on Civilian BiodefenseQ33901607
Replication of Yersinia pestis in interferon gamma-activated macrophages requires ripA, a gene encoded in the pigmentation locusQ33943840
TNF-alpha and IL-12: a balancing act in macrophage functioningQ34184417
Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activityQ34201893
Yersinia pestis (plague) vaccinesQ34324211
The Bordetella bronchiseptica type III secretion system inhibits gamma interferon production that is required for efficient antibody-mediated bacterial clearanceQ34334393
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cellsQ34388169
Exacerbated susceptibility to infection-stimulated immunopathology in CD1d-deficient miceQ34440132
Association between virulence of Yersinia pestis and suppression of gamma interferon and tumor necrosis factor alpha.Q34520336
Interleukin-10 and inhibition of innate immunity to Yersiniae: roles of Yops and LcrV (V antigen)Q35159314
Antibody regulation of Tcell immunity: implications for vaccine strategies against intracellular pathogensQ35648247
Interferon-gamma activation of polymorphonuclear neutrophil functionQ35750735
Immune responses to Yersinia enterocolitica in susceptible BALB/c and resistant C57BL/6 mice: an essential role for gamma interferonQ35783031
Insights into mechanisms of antibody-mediated immunity from studies with Cryptococcus neoformansQ36174591
Uptake of Leishmania major by dendritic cells is mediated by Fcgamma receptors and facilitates acquisition of protective immunityQ36227843
Fibrin-mediated protection against infection-stimulated immunopathologyQ36370606
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectYersinia pestisQ153875
P304page(s)3381-3386
P577publication date2006-06-01
P1433published inInfection and ImmunityQ6029193
P1476titleGamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infection
P478volume74

Reverse relations

cites work (P2860)
Q91760327A Combined YopB and LcrV Subunit Vaccine Elicits Protective Immunity against Yersinia Infection in Adult and Infant Mice
Q92090453A Recombinant Attenuated Yersinia pseudotuberculosis Vaccine Delivering a Y. pestis YopENt138-LcrV Fusion Elicits Broad Protection against Plague and Yersiniosis in Mice
Q36898462A nasal interleukin-12 DNA vaccine coexpressing Yersinia pestis F1-V fusion protein confers protection against pneumonic plague
Q33816162A parenteral DNA vaccine protects against pneumonic plague
Q33557963Absence of inflammation and pneumonia during infection with nonpigmented Yersinia pestis reveals a new role for the pgm locus in pathogenesis
Q35418294Advanced Development of the rF1V and rBV A/B Vaccines: Progress and Challenges
Q37066749An IL-12 DNA vaccine co-expressing Yersinia pestis antigens protects against pneumonic plague
Q34163944An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague
Q41441607Antibodies and cytokines independently protect against pneumonic plague.
Q34045080Biosafety level 2 model of pneumonic plague and protection studies with F1 and Psa.
Q33310431Broad T cell immunity to the LcrV virulence protein is induced by targeted delivery to DEC-205/CD205-positive mouse dendritic cells
Q33500145CD8(+) T cells restrict Yersinia pseudotuberculosis infection: bypass of anti-phagocytosis by targeting antigen-presenting cells
Q36845217Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ.
Q36984064Cell-mediated defense against Yersinia pestis infection
Q35810279Complete Protection against Pneumonic and Bubonic Plague after a Single Oral Vaccination.
Q34189701Contrasted patterns of selection on MHC-linked microsatellites in natural populations of the Malagasy plague reservoir
Q36628038Current challenges in the development of vaccines for pneumonic plague
Q37355852D27-pLpxL, an avirulent strain of Yersinia pestis, primes T cells that protect against pneumonic plague
Q37450884Dual-function antibodies to Yersinia pestis LcrV required for pulmonary clearance of plague
Q35113336Enhancement of immune response to an antigen delivered by vaccinia virus by displaying the antigen on the surface of intracellular mature virion
Q33798021Evaluation of imipenem for prophylaxis and therapy of Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague
Q34633478HSP70 domain II of Mycobacterium tuberculosis modulates immune response and protective potential of F1 and LcrV antigens of Yersinia pestis in a mouse model
Q64092755Human Macrophages Clear the Biovar Microtus Strain of More Efficiently Than Murine Macrophages
Q37287818Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis.
Q34786724IL-17 contributes to cell-mediated defense against pulmonary Yersinia pestis infection
Q33584403Immune defense against pneumonic plague
Q40512106Immunology of Yersinia pestis Infection
Q41384167Improving the Th1 cellular efficacy of the lead Yersinia pestis rF1-V subunit vaccine using SA-4-1BBL as a novel adjuvant
Q90169705Induction of protective anti-plague immune responses by self-adjuvanting bionanoparticles derived from the engineered Yersinia pestis
Q36288336Induction of pulmonary mucosal immune responses with a protein vaccine targeted to the DEC-205/CD205 receptor
Q37415511Innate immune response during Yersinia infection: critical modulation of cell death mechanisms through phagocyte activation
Q36594020Interaction between Yersinia pestis and the host immune system
Q36911486Intranasal prophylaxis with CpG oligodeoxynucleotide can protect against Yersinia pestis infection
Q34819434Involvement of CD8+ T cell-mediated immune responses in LcrV DNA vaccine induced protection against lethal Yersinia pestis challenge
Q34298699LcrV delivered via type III secretion system of live attenuated Yersinia pseudotuberculosis enhances immunogenicity against pneumonic plague
Q36960814Lipid A mimetics are potent adjuvants for an intranasal pneumonic plague vaccine
Q34645327Mathematical relationship between cytokine concentrations and pathogen levels during infection
Q41447516Modulation of dendritic cell differentiation and function by YopJ of Yersinia pestis
Q41400297Multiple antigen peptide containing B and T cell epitopes of F1 antigen of Yersinia pestis showed enhanced Th1 immune response in murine model
Q33786763Multiple roles of Myd88 in the immune response to the plague F1-V vaccine and in protection against an aerosol challenge of Yersinia pestis CO92 in mice
Q35836140Nanoparticulate STING agonists are potent lymph node-targeted vaccine adjuvants.
Q33502706O antigen allows B. parapertussis to evade B. pertussis vaccine-induced immunity by blocking binding and functions of cross-reactive antibodies
Q27343051Opposing roles for interferon regulatory factor-3 (IRF-3) and type I interferon signaling during plague
Q36372952Oral administration of a recombinant attenuated Yersinia pseudotuberculosis strain elicits protective immunity against plague
Q56706594Plague
Q36099515Protection against pneumonic plague following oral immunization with a non-replicating vaccine
Q37688618Rational considerations about development of live attenuated Yersinia pestis vaccines
Q36373952Recombinant Bivalent Fusion Protein rVE Induces CD4+ and CD8+ T-Cell Mediated Memory Immune Response for Protection Against Yersinia enterocolitica Infection
Q92644859Robust Th1 cellular and humoral responses generated by the Yersinia pestis rF1-V subunit vaccine formulated to contain an agonist of the CD137 pathway do not translate into increased protection against pneumonic plague
Q34380204TNFα and IFNγ contribute to F1/LcrV-targeted immune defense in mouse models of fully virulent pneumonic plague.
Q41432452Targeting of LcrV virulence protein from Yersinia pestis to dendritic cells protects mice against pneumonic plague.
Q33496136The role of relA and spoT in Yersinia pestis KIM5 pathogenicity
Q36845312Type III secretion decreases bacterial and host survival following phagocytosis of Yersinia pseudotuberculosis by macrophages
Q41451306Vaccination with live Yersinia pestis primes CD4 and CD8 T cells that synergistically protect against lethal pulmonary Y. pestis infection
Q34290878Yersinia pestis biovar Microtus strain 201, an avirulent strain to humans, provides protection against bubonic plague in rhesus macaques
Q41437577Yersinia pestis can bypass protective antibodies to LcrV and activation with gamma interferon to survive and induce apoptosis in murine macrophages
Q33675781Yersinia pestis with regulated delayed attenuation as a vaccine candidate to induce protective immunity against plague
Q35073117YopP-expressing variant of Y. pestis activates a potent innate immune response affording cross-protection against yersiniosis and tularemia [corrected].
Q64906371γ-herpesvirus latency attenuates Mycobacterium tuberculosis infection in mice.

Search more.