TNFα and IFNγ contribute to F1/LcrV-targeted immune defense in mouse models of fully virulent pneumonic plague.

scientific article

TNFα and IFNγ contribute to F1/LcrV-targeted immune defense in mouse models of fully virulent pneumonic plague. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.VACCINE.2010.08.099
P932PMC publication ID2997115
P698PubMed publication ID20840834
P5875ResearchGate publication ID46272568

P50authorJeffrey J AdamoviczQ55778983
Kei AmemiyaQ89513808
P2093author name stringJames B Bliska
Jr-Shiuan Lin
Stephen T Smiley
David S Perlin
Steven Park
Christopher K Cote
Jim Hill
P2860cites workInterleukin-12 and the regulation of innate resistance and adaptive immunityQ29614602
Yersinia pestis--etiologic agent of plagueQ29619320
Pathogenesis of Yersinia pestis infection in BALB/c mice: effects on host macrophages and neutrophilsQ33225645
Absence of inflammation and pneumonia during infection with nonpigmented Yersinia pestis reveals a new role for the pgm locus in pathogenesisQ33557963
Immune defense against pneumonic plagueQ33584403
Human immune response to a plague vaccine comprising recombinant F1 and V antigensQ33788286
The yersiniabactin transport system is critical for the pathogenesis of bubonic and pneumonic plagueQ33826085
Plague as a biological weapon: medical and public health management. Working Group on Civilian BiodefenseQ33901607
Replication of Yersinia pestis in interferon gamma-activated macrophages requires ripA, a gene encoded in the pigmentation locusQ33943840
Anti-LcrV antibody inhibits delivery of Yops by Yersinia pestis KIM5 by directly promoting phagocytosisQ34034184
Progression of primary pneumonic plague: a mouse model of infection, pathology, and bacterial transcriptional activityQ34201893
Risk of person-to-person transmission of pneumonic plagueQ34406504
Association between virulence of Yersinia pestis and suppression of gamma interferon and tumor necrosis factor alpha.Q34520336
Administration of antibody to the lung protects mice against pneumonic plague.Q34601788
A plasminogen-activating protease specifically controls the development of primary pneumonic plagueQ34606584
Suppression of cytokines in mice by protein A-V antigen fusion peptide and restoration of synthesis by active immunization.Q35429159
Regions of Yersinia pestis V antigen that contribute to protection against plague identified by passive and active immunizationQ35557573
Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred miceQ35689282
Development of in vitro correlate assays of immunity to infection with Yersinia pestis.Q35783560
Current challenges in the development of vaccines for pneumonic plagueQ36628038
Single-dose, virus-vectored vaccine protection against Yersinia pestis challenge: CD4+ cells are required at the time of challenge for optimal protectionQ37066697
Dual-function antibodies to Yersinia pestis LcrV required for pulmonary clearance of plagueQ37450884
Predictive models and correlates of protection for testing biodefence vaccinesQ37745002
Cell-mediated protection against pulmonary Yersinia pestis infectionQ39393406
Synergistic protection of mice against plague with monoclonal antibodies specific for the F1 and V antigens of Yersinia pestisQ39741669
Modified caspase-3 assay indicates correlation of caspase-3 activity with immunity of nonhuman primates to Yersinia pestis infection.Q39755573
Neutralization of Yersinia pestis-mediated macrophage cytotoxicity by anti-LcrV antibodies and its correlation with protective immunity in a mouse model of bubonic plagueQ40008433
Anti-V antigen antibody protects macrophages from Yersinia pestis -induced cell death and promotes phagocytosisQ40724134
CpG oligodeoxynucleotides augment the murine immune response to the Yersinia pestis F1-V vaccine in bubonic and pneumonic models of plague.Q41438984
Antibodies and cytokines independently protect against pneumonic plague.Q41441607
Development of a recombinant vaccine against aerosolized plagueQ41450195
Immunogenicity of the rF1+rV vaccine for plague with identification of potential immune correlatesQ41451391
Gamma interferon, tumor necrosis factor alpha, and nitric oxide synthase 2, key elements of cellular immunity, perform critical protective functions during humoral defense against lethal pulmonary Yersinia pestis infectionQ41453869
Stat 4 but not Stat 6 mediated immune mechanisms are essential in protection against plagueQ41461188
Oral immunisation with live aroA attenuated Salmonella enterica serovar Typhimurium expressing the Yersinia pestis V antigen protects mice against plagueQ41466529
Protection conferred by a fully recombinant sub-unit vaccine against Yersinia pestis in male and female mice of four inbred strainsQ41478713
The SCID/Beige mouse as a model to investigate protection against Yersinia pestisQ41483548
Protection against experimental bubonic and pneumonic plague by a recombinant capsular F1-V antigen fusion protein vaccineQ41485426
Protection of mice from fatal bubonic and pneumonic plague by passive immunization with monoclonal antibodies against the F1 protein of Yersinia pestisQ41488613
Immunity in plague; a critical consideration of some recent studies.Q41575211
New drug and biological drug products; evidence needed to demonstrate effectiveness of new drugs when human efficacy studies are not ethical or feasible. Final rule.Q53432317
PlagueQ56706594
PlagueQ84740727
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages6
P304page(s)357-362
P577publication date2010-09-15
P1433published inVaccineQ7907941
P1476titleTNFα and IFNγ contribute to F1/LcrV-targeted immune defense in mouse models of fully virulent pneumonic plague
P478volume29

Reverse relations

cites work (P2860)
Q92090453A Recombinant Attenuated Yersinia pseudotuberculosis Vaccine Delivering a Y. pestis YopENt138-LcrV Fusion Elicits Broad Protection against Plague and Yersiniosis in Mice
Q88964571A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model
Q35418294Advanced Development of the rF1V and rBV A/B Vaccines: Progress and Challenges
Q33601814Direct neutralization of type III effector translocation by the variable region of a monoclonal antibody to Yersinia pestis LcrV
Q93375305Escherichia coli expressed flagellin C (FliC) of Salmonella Typhi improved the protective efficacy of YopE against plague infection
Q33798021Evaluation of imipenem for prophylaxis and therapy of Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague
Q39736724Fibrin facilitates both innate and T cell-mediated defense against Yersinia pestis
Q93015468Flagellin adjuvanted F1/V subunit plague vaccine induces T cell and functional antibody responses with unique gene signatures
Q34633478HSP70 domain II of Mycobacterium tuberculosis modulates immune response and protective potential of F1 and LcrV antigens of Yersinia pestis in a mouse model
Q34786724IL-17 contributes to cell-mediated defense against pulmonary Yersinia pestis infection
Q47293934Immunisation of two rodent species with new live-attenuated mutants of Yersinia pestis CO92 induces protective long-term humoral- and cell-mediated immunity against pneumonic plague
Q40512106Immunology of Yersinia pestis Infection
Q41384167Improving the Th1 cellular efficacy of the lead Yersinia pestis rF1-V subunit vaccine using SA-4-1BBL as a novel adjuvant
Q36288336Induction of pulmonary mucosal immune responses with a protein vaccine targeted to the DEC-205/CD205 receptor
Q35530270Intranasal administration of an inactivated Yersinia pestis vaccine with interleukin-12 generates protective immunity against pneumonic plague
Q40485593Intranasal delivery of a protein subunit vaccine using a Tobacco Mosaic Virus platform protects against pneumonic plague
Q41400297Multiple antigen peptide containing B and T cell epitopes of F1 antigen of Yersinia pestis showed enhanced Th1 immune response in murine model
Q33786763Multiple roles of Myd88 in the immune response to the plague F1-V vaccine and in protection against an aerosol challenge of Yersinia pestis CO92 in mice
Q28678943Mutated and bacteriophage T4 nanoparticle arrayed F1-V immunogens from Yersinia pestis as next generation plague vaccines
Q38671761Novel CTL epitopes identified through a Y. pestis proteome-wide analysis in the search for vaccine candidates against plague
Q91826998Oral vaccination with live attenuated Yersinia pseudotuberculosis strains delivering a FliC180-LcrV fusion antigen confers protection against pulmonary Y. Pestis infection
Q38514208Plague vaccines: current developments and future perspectives
Q26823422Protecting against plague: towards a next-generation vaccine
Q92644859Robust Th1 cellular and humoral responses generated by the Yersinia pestis rF1-V subunit vaccine formulated to contain an agonist of the CD137 pathway do not translate into increased protection against pneumonic plague
Q92241416Shift from primary pneumonic to secondary septicemic plague by decreasing the volume of intranasal challenge with Yersinia pestis in the murine model
Q55361721Single vector platform vaccine protects against lethal respiratory challenge with Tier 1 select agents of anthrax, plague, and tularemia.
Q90696345Single-dose combination nanovaccine induces both rapid and long-lived protection against pneumonic plague
Q33650538TNFα and IFNγ but not perforin are critical for CD8 T cell-mediated protection against pulmonary Yersinia pestis infection
Q38589273The role of immune correlates and surrogate markers in the development of vaccines and immunotherapies for plague
Q35091255Yersinia pestis YopE contains a dominant CD8 T cell epitope that confers protection in a mouse model of pneumonic plague
Q35073117YopP-expressing variant of Y. pestis activates a potent innate immune response affording cross-protection against yersiniosis and tularemia [corrected].

Search more.